Evolutionary forces drive a glaring gender imbalance in the occurrence of many health conditions, including autism, a team of genetics researchers has concluded.
DALLAS – Feb. 24, 2021 – Using machine learning tools to analyze hundreds of proteins, UT Southwestern researchers have identified a group of biomarkers in blood that could lead to an earlier diagnosis of children with autism spectrum disorder (ASD) and, in turn, more effective therapies sooner.
Efforts to improve the social success of autistic adolescents and adults have often focused on teaching them ways to think and behave more like their non-autistic peers and to hide the characteristics that define them as autistic.
DALLAS – Feb. 3, 2021 – Inactivating a gene in young songbirds that’s closely linked with autism spectrum disorder (ASD) prevents the birds from forming memories necessary to accurately reproduce their fathers’ songs, a new study led by UT Southwestern shows.
Researchers have demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells.
A collaborative study found that compared with their non-autistic peers, young autistic drivers have lower rates of moving violations and license suspensions, as well as similar to lower crash rates.
Researchers at Washington University School of Medicine in St. Louis have found that immune cells stationed in sinuses in the meninges — the covering of the brain and spinal cord — monitor the brain and initiate an immune response if they detect a problem.
UC Davis MIND Institute researchers used machine learning to crunch 10,000 autoantibody pattern combinations to identify maternal biomarkers associated with a sub-type of autism. The findings have implications for early diagnosis and intervention.
Mutations that occur in certain DNA regions, called tandem repeats, may play a significant role in autism spectrum disorders, according to research led by Melissa Gymrek, assistant professor in the UC San Diego Department of Computer Science and Engineering and School of Medicine. The study, which was published in Nature on Jan. 14, was co-authored by UCLA professor of human genetics Kirk Lohmueller and highlights the contributions these understudied mutations can make to disease.
As a former school nurse in the Columbia Public Schools, Gretchen Carlisle would often interact with students with disabilities who took various medications or had seizures throughout the day.
Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder.
A unifying explanation of the cause of autism and the reason for its rising prevalence has eluded scientists for decades, but a theoretical model published in the journal Medical Hypotheses describes the cause as a combination of socially valued traits, common in autism, and any number of co-occurring disabilities.
The Seaver Autism Center for Research and Treatment at the Icahn School of Medicine at Mount Sinai and Rumi Scientific announced today that they will team up to initiate a drug discovery pipeline for rare genetic disorders that carry a high risk of autism.
People with certain genetic conditions are likely to have significant symptoms of autism, even if they do not meet all diagnostic criteria, a study concludes.
Notable executive Sheri Marino joins Hackensack Meridian Health Foundation
DALLAS – Dec. 22, 2020 – UT Southwestern scientists have adapted a classic research technique called forward genetics to identify new genes involved in autism spectrum disorder (ASD). In a study published this week in eLife, the researchers used this approach in mice to find one such gene called KDM5A.
Researchers found that a long-accepted theory about brain size in some children with autism may not be true. In a separate study, they linked development of white matter with changes in autism symptom severity.
A deficiency in Vitamin D on the mother's side could explain why Autism spectrum disorder is three times more common in boys, say researchers from The University of Queensland.
A new drug discovered through a research collaboration between the University at Buffalo and Tetra Therapeutics took a major step toward becoming a first-in-class treatment for Fragile X Syndrome, a leading genetic cause of autism.
Results from phase two study show improved language and daily functioning among participants
UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.
In children with autism, repetitive behaviors and gastrointestinal problems may be connected, new research has found. The study found that increased severity of other autism symptoms was also associated with more severe constipation, stomach pain and other gut difficulties.
A team of researchers from Michigan State University, University of Michigan and tech-training company SIMmersion received a $3 million grant from the National Institute of Mental Health to develop a virtual reality training tool for youth with autism spectrum disorder, or ASD, to improve their social skills as they transition from high school to the workforce.
Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.
Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Specific regions in cord blood DNA can help identify kids who might develop autism, a study led by UC Davis MIND Institute researchers. The findings may hold clues for early diagnosis and intervention.
Researchers at Mount Sinai have proposed a groundbreaking new way to study the interaction between complex biological systems in the body and the environment. Their theory suggests the existence of “biodynamic interfaces,” an intermediate entity between the two realms, as opposed to conventional approaches that analyze individual aspects of the interaction between the environment and humans in isolation, according to a paper published in BioEssays in October.
Two prominent early intervention models for toddlers with autism show a very similar impact, whether delivered at 15-hours or 25-hours per week intensities, a study led by UC Davis MIND Institute researchers has found.
Autism is considered a disorder of the brain. But a new study suggests that the peripheral nervous system, the nerves that control our sense of touch, pain and other sensations, may play a role as well. The exploratory study is published in the October 14, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A new, residential four-year college program for students with intellectual disabilities is the first of its kind in the west and is expected to serve as a model for other California schools.
The Society for Obstetric Anesthesia and Perinatology (SOAP),the American Society of Anesthesiologists (ASA), the Society for Pediatric Anesthesia (SPA) the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM) aim to clearly reassure pregnant women that the article “Association Between Epidural Analgesia During Labor and Risk of Autism Spectrum Disorders in Offspring,” a new retrospective database study published in JAMA Pediatrics on October 12th, 2020 does not provide credible scientific evidence that epidurals for pain relief cause autism.
A grant from the National Institutes of Health will allow a Penn State College of Medicine researcher to lead a three-year, multi-institution project to create an atlas of developing mice brains.
A study of pregnant mice found high levels of folic acid were associated with significant changes in brain development of offspring.
Training parents of children with autism spectrum disorder virtually about early behavioral intervention is an accessible and effective approach during the coronavirus pandemic or in other instances when in-person instruction is not possible, according to a Rutgers researcher.
Researchers at the Institute for Autism Research at Canisius College find innovative outpatient treatment (MAXout) highly effective for children with higher-functioning autism spectrum disorder (HFASD). Children demonstrate significant improvements in social skills, ASD symptoms, social-cognitive skills, and problem behaviors.
A study of more than 3.5 million Nordic children suggests that the risk of autism spectrum disorder (ASD) may increase slightly for each week a child is born before or after 40 weeks of gestation.
The Yang-Tan Institute of Employment and Disability at Cornell University has joined a multi-institution team that has received a $5 million grant from the National Science Foundation (NSF) to help create better job outcomes for people with autism spectrum disorder.
Why do some adolescents take more risks than others? New research from University of Delaware Biomedical Engineer Curtis Johnson and graduate student Grace McIlvain suggests that two centers in the adolescent brain, one that makes them want to take risks and the other prevents them from acting on those impulses, physically mature at different rates and that adolescents with large differences in the rate of development between these two brain regions are more likely to be risk-takers.
A study on serotonin, a mood-regulating molecule in the brain that regulates many brain synapses, is helping to unravel the puzzle surrounding its role in autism. The activity and regulation of the serotonin transporter (SERT), protein is critically dependent on a number of other proteins that tell the protein where to locate on nerve cells and how to act. Shifts in the transporter’s activity can significantly impact the ability of serotonin to act in the brain.
Developing a physiological test for diagnosing autism spectrum disorder (ASD), one that measures certain components in the blood, has the potential to be a paradigm shift for diagnosing ASD. However, the large heterogeneity of how ASD affects individuals has long been viewed as a key obstacle to the development of such a test. Research conducted at Rensselaer Polytechnic Institute, and published online today in the journal Research in Autism Spectrum Disorders, represents a significant step toward addressing this challenge.
Molecules known as tRNAs are often overlooked in studies of disease processes. Researchers have now found that a mutation in a tRNA gene called n-Tr20—expressed only in the brain—can disrupt the landscape of entire cells, leading to chain reactions that alter brain function and behavior.
Using a simple 'thermometer scale survey' to measure public attitudes towards people with autism could help improve public understanding and acceptance, say researchers.
Study identifies genetic link between cholesterol alterations and autism. Lipid abnormalities found in nearly 7 percent of individuals diagnosed with an autism-spectrum disorder. Results can inform the design of precision-targeted therapies for this form of autism. Findings set the stage for studies to determine the clinical value of lipid abnormalities as biomarkers for autism.
Most of modern medicine has physical tests or objective techniques to define much of what ails us.
Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found. Offspring sex may also interact with maternal immune conditions to influence outcomes, particularly in terms of a child’s cognition.
Autism spectrum disorder (ASD) is rarely diagnosed until symptoms arise, often well into childhood. Evidence however, is mounting that developmental abnormalities likely emerge in the brain long before then: early identification of babies at risk for ASD could allow for interventions that would improve their developmental outcomes.
A new UC Davis Health study found that common gastrointestinal (GI) symptoms such as diarrhea, constipation and bloating are linked to troubling sleep problems, self-harm and physical complaints in preschool children. According to the study, published Aug. 6 in Autism Research, these GI symptoms are much more common and potentially disruptive in young kids with autism.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right