Feature Channels: Personalized Medicine

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Released: 25-Oct-2021 1:50 PM EDT
مايو كلينك تتعاون مع شركة بيرسونالس لتوسيع الاختبارات الجينومية للسرطان
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا، ومينلو بارك، ولاية كاليفورنيا- أعلنت مايو كلينك عن اتفاقية يوم الثلاثاء، 12 تشرين الأول/أكتوبر، ستسمح لها بتقديم تسلسل جينومي شامل للسرطان من الدرجة السريرية لمرضى السرطان الذين يختارون المشاركة.

Released: 25-Oct-2021 1:45 PM EDT
$2.1 Million Gift Launches Comprehensive Breast Cancer Database
UC San Diego Health

Philanthropists Richard and Carol Dean Hertzberg have committed $2.1 million to develop and maintain the Dean-Hertzberg Breast Cancer Database System Initiative at UC San Diego Health Moores Cancer Center to support the work of Anne Wallace, MD and her collaborators at Moores Cancer Center.

Released: 25-Oct-2021 1:45 PM EDT
A Mayo Clinic colabora com a Personalis Inc. com o objetivo de expandir os exames genômicos oncológicos
Mayo Clinic

a Mayo Clinic anunciou na terça-feira, 12 de outubro, um acordo que lhe permitirá oferecer sequenciamento genômico oncológico abrangente de uso clínico para os pacientes portadores da doença que decidirem participar.

Released: 25-Oct-2021 1:40 PM EDT
Mayo Clinic colabora con Personalis Inc. para ampliar pruebas genómicas del cáncer
Mayo Clinic

Mayo Clinic anunció un acuerdo el martes 12 de octubre que le permitirá ofrecer secuenciación genómica integral del cáncer de grado clínico a pacientes con cáncer que decidan participar.

Released: 18-Oct-2021 11:35 AM EDT
Moffitt Researchers Use Computer Modeling to Predict Patient Tumor Responses to Radiation Therapy
Moffitt Cancer Center

Researchers at Moffitt Cancer Center are trying to improve the personalization of radiation therapy through computer modeling. In a new study published in the journal Neoplasia, they model how interactions between cancer cells and immune cells, and their subsequent responses to radiation, impact the tumor. They propose their model may help to predict how patients respond to radiation therapy.

Released: 13-Oct-2021 3:25 PM EDT
At Initial Cancer Diagnosis, a Deeply Personalized Assessment
UC San Diego Health

UC San Diego researchers report that conducting genomic evaluations of advanced malignancies can be effective in guiding first-line-of-treatment, rather than waiting until standard-of-care therapies have failed.

Newswise: New Research Center Brings Genomic Medicine to Individuals of Admixed Ancestry
Released: 12-Oct-2021 11:10 AM EDT
New Research Center Brings Genomic Medicine to Individuals of Admixed Ancestry
UC San Diego Health

Researchers at UC San Diego School of Medicine awarded $11.7 million by National Institutes of Health to identify genomic and socioeconomic factors contributing to health and disease in admixed individuals. The new center aims to bring the genomic revolution to all.

Released: 12-Oct-2021 9:45 AM EDT
Mayo Clinic collaborates with Personalis Inc. to expand cancer genomic testing
Mayo Clinic

Mayo Clinic announced an agreement on Tuesday, Oct. 12 that will allow it to offer clinical-grade comprehensive cancer genomic sequencing to cancer patients who choose to participate. Test results will be available to patients and their treating health care providers to guide therapeutic decisions, advance cancer research, and support the development of new diagnostic tests and therapies for cancer treatment.

Released: 8-Oct-2021 12:15 PM EDT
Personalized Medicine: Platform Enables Comparative Research on Cancerous Tumors
American Technion Society

An international team of researchers has developed an algorithm that enhances the ability to compare tumors between different patients, overcoming high inter-patient variability. Although the researchers tested the algorithm on leukemia tumors, they believe that it will also be relevant for other cancer types.

Released: 8-Oct-2021 10:35 AM EDT
University of Kentucky Study Suggests Personalized Medicine May be the Future of Alzheimer’s Disease Treatment
University of Kentucky

A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer’s disease pathology.

Released: 30-Sep-2021 6:15 PM EDT
Most cases of never-smokers’ lung cancer treatable with mutation-targeting drugs
Washington University in St. Louis

A new study from Washington University School of Medicine in St. Louis estimates that 78% to 92% of lung cancers in patients who have never smoked can be treated with precision drugs already approved by the Food and Drug Administration to target specific mutations in a patient’s tumor.

Newswise: Looking Beyond DNA to See Cancer with New Clarity
Released: 30-Sep-2021 2:40 PM EDT
Looking Beyond DNA to See Cancer with New Clarity
UC San Diego Health

In three Science papers, UC San Diego and UC San Francisco researchers mapped out how hundreds of gene mutations involved in cancer affect the discrete groups of proteins that are the ultimate actors behind the disease. The work points the way to identifying new precision treatments.

Released: 29-Sep-2021 11:05 AM EDT
Mount Sinai Scientists Show That a Novel Therapy Could Be Effective Against Pediatric Leukemia
Mount Sinai Health System

Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.

Released: 29-Sep-2021 8:00 AM EDT
MD Anderson and Siemens Healthineers collaborating to enable consistent clinical implementation of quantitative MRI
University of Texas MD Anderson Cancer Center

MD Anderson and Siemens Healthineers have announced the collaborative development of an education program focused on enabling the implementation of consistent, high-quality MRI in radiation oncology.

Newswise:Video Embedded research-autopsy-helps-scientists-study-why-certain-cancer-therapies-stop-working
VIDEO
Released: 28-Sep-2021 12:05 PM EDT
‘Research autopsy’ helps scientists study why certain cancer therapies stop working
Ohio State University Wexner Medical Center

A new research study at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) turns cancer scientists into molecular detectives, searching for clues for why certain cancers are able to spread and evolve by studying tissues collected within hours of death.

Released: 28-Sep-2021 9:30 AM EDT
MD Anderson and BostonGene announce strategic alliance to advance personalized cancer diagnostics and treatments
University of Texas MD Anderson Cancer Center

MD Anderson and BostonGene today announced a strategic alliance to advance the development and clinical integration of multiplatform biomarker signatures.

Newswise: Three Advances in Breast Cancer Treatment are Saving More Lives
Released: 22-Sep-2021 4:20 PM EDT
Three Advances in Breast Cancer Treatment are Saving More Lives
Rutgers Cancer Institute of New Jersey

The outlook for patients diagnosed with breast cancer has been changing for the better over time thanks to surgical advances, clinical trials & a more personalized treatment approach. Dr. Lindsay Potdevin, surgical oncologist at Rutgers Cancer Institute of New Jersey, shares how these advances are improving the lives of patients.

Released: 21-Sep-2021 11:50 AM EDT
Memorial Sloan Kettering Cancer Center Launches New Center to Expand Commitment to Meeting the Unique Needs of Adolescents and Young Adults with Cancer
Memorial Sloan Kettering Cancer Center

While overall cancer cases are declining, they are on the rise in older adolescents and young adults. Today, Memorial Sloan Kettering Cancer Center (MSK) announces the establishment of the Lisa and Scott Stuart Center for Adolescent and Young Adult Cancers (the Stuart Center), dramatically expanding MSK’s already robust efforts to address the very specific, and often unmet, needs of this patient population.

Released: 9-Sep-2021 11:40 AM EDT
‘Molecular Twin’ Initiative Will Help Advance Precision Cancer Treatment
Cedars-Sinai

Cedars-Sinai Cancer and Tempus, a leader in artificial intelligence and precision medicine, are harnessing the power of big data and AI to design personalized cancer treatment options by creating virtual replicas of patients’ DNA, RNA, protein and other information to help identify the most effective approach to each individual's disease.

Released: 1-Sep-2021 6:55 PM EDT
Researchers Discover Test to Predict Which Patients with Rare Blood Disease Will Respond to Only FDA-Approved Treatment, and Identify Alternative Therapy
Perelman School of Medicine at the University of Pennsylvania

New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.

Released: 1-Sep-2021 8:45 AM EDT
Liquid biopsies may aid diagnosis, treatment of bladder, nerve tumors
Washington University in St. Louis

Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

Released: 31-Aug-2021 8:15 AM EDT
A Pediatric Research Institution is Setting the Pace for Monitoring SARS-CoV-2 Mutations and COVID-19 Variants
Children's Hospital Los Angeles

Scientists at Children’s Hospital Los Angeles have been paying close attention to the behavior of SARS-CoV-2, since the beginning of the pandemic.

Released: 20-Aug-2021 2:45 PM EDT
GYNOCARE COST Creates International Research Collab on Rare Cancers Affecting Millions of Women Annually
Sbarro Health Research Organization (SHRO)

Sbarro Health Research Organization (SHRO) Founder and Director, Antonio Giordano, M.D., Ph.D., of Temple University and the University of Siena, Italy, is part of the GYNOCARE COST Action (CA18117) chaired by Prof Jean Calleja Agius of the University of Malta.

Released: 19-Aug-2021 3:50 PM EDT
BIDMC opens first-of-its-kind Spatial Technologies Unit to Massachusetts’ precision medicine research community
Beth Israel Deaconess Medical Center

With the goal of dramatically accelerating discoveries in health and disease, Beth Israel Deaconess Medical Center has opened a Spatial Technologies Unit, the first center in Massachusetts and one of the first of its kind worldwide. The new space will provide access to ground-breaking technologies that allow scientists to examine cells as they function within intact tissues. Made possible by a grant from the Massachusetts Life Sciences Center, the BIDMC unit will be a nexus of the state’s precision medicine community, empowering researchers across healthcare, academia, research and industry.

Released: 19-Aug-2021 3:00 PM EDT
VIDEO AND TRANSCRIPT AVAILABLE: Breakthrough Cases and COVID Boosters: Live Expert Panel for August 18, 2021
Newswise

Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.

Released: 18-Aug-2021 8:40 AM EDT
Toward Better Medicine
Harvard Medical School

• Catalyzing gift will support precision medicine efforts at Harvard Medical School and Clalit Research Institute in Israel through data science, clinical research, and training. • Work marks first-of-its-kind collaboration between Harvard Medical School and an Israeli health care system. • Collaboration melds Harvard Medical School’s and Clalit’s capabilities in computational biomedicine and big-data analysis.

Released: 13-Aug-2021 4:20 PM EDT
An Emerging Clue to Cancer Therapy: Radiotherapy-Induced Autophagy May Enhance Modulation of Cell Cycle
Sbarro Health Research Organization (SHRO)

Building on prior success combining Cyclin-Dependent Kinase (CDK) inhibitors with hormone therapy to treat breast cancer, researchers are now exploring the potential integration of CDK inhibitors with radiotherapy in a paper issued in the International Journal of Molecular Sciences.

12-Aug-2021 3:05 AM EDT
Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects
University of California San Diego

A new cancer immunotherapy pairs ultrasound with specially engineered CAR T cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice.

   
Released: 10-Aug-2021 11:25 AM EDT
CorEvitas Announces First Patient Enrollment in a New Biorepository Study focused on Precision Medicine for JAK Inhibitors in Rheumatoid Arthritis
CorEvitas

CorEvitas, LLC, the leading sponsor of registries in autoimmune and inflammatory diseases announces first patient enrollment in a new biospecimen study for patients enrolled in its rheumatology registries. Eligible rheumatology registry patients will contribute biological specimens that will be linked to longitudinal provider reported clinical and patient reported outcomes.

Released: 5-Aug-2021 1:45 PM EDT
When Provided Personalized Health Resources, Patients Often Share with Others
University of Chicago Medical Center

A survey of participants in a clinical trial for CommunityRx, a community resource referral intervention, found that nearly half of users reported sharing their personalized health resources with at least one other person.

Released: 4-Aug-2021 6:30 PM EDT
Study Confirms Effectiveness of New Personalized Approach for Radiation Therapy
Cleveland Clinic

Researchers from Cleveland Clinic, Case Western Reserve University School of Medicine, and Moffitt Cancer Center have found that the genomic adjusted radiation dose (GARD) may be used to personalize radiotherapy (RT) to maximize the therapeutic effect of a given physical RT dose. This research was published Aug. 4 in The Lancet Oncology journal.

Released: 3-Aug-2021 1:20 PM EDT
The Future of Personalized Medicine Is in Unlocking the Hidden Mechanism That Controls Which Genes Are Activated, Researcher Says
McMaster University

New research by McMaster University evolutionary biologist Rama Singh suggests there is a layer hidden in our cells that controls how genes interact, and how the many billions of possible combinations produce certain results.

Released: 2-Aug-2021 6:05 PM EDT
دراسة جديدة في مايو تُظهر أن التغييرات الجينية تؤثر على الاستجابة لعلاج الشقيقة
Mayo Clinic

الشقيقة (الصداع النصفي) يصيب الملايين من الناس حول العالم. ومع ذلك، فإن تحديد دواء وقائي فعال- أي الأدوية المتاحة فقط بوصفة طبية والأكثر شيوعًا للمصابين بالشقيقة- يظل عملية طويلة ومعقدة. غالبًا ما يتنقل المرضى بين الأدوية لأسابيع أو شهور حتى تتحقق استجابة علاجية.

Released: 2-Aug-2021 6:05 PM EDT
De acordo com novo o estudo da Mayo, as variantes genéticas influenciam a resposta ao tratamento da enxaqueca
Mayo Clinic

Enxaquecas atormentam milhões de pessoas em todo o mundo.No entanto, encontrar um medicamento preventivo eficaz, um medicamento mais comumente prescrito para pessoas com diagnóstico de enxaqueca, continua sendo um processo longo e complexo.

Released: 2-Aug-2021 6:05 PM EDT
根据妙佑医疗国际(Mayo Clinic)的新研究,基因变异会影响偏头痛治疗反应
Mayo Clinic

偏头痛困扰着全世界数百万人。然而,确定一种有效的预防药物 ― 偏头痛患者最常用的处方药 ― 仍然是一个漫长而复杂的过程。患者通常连续用药数周或数月,才能出现治疗反应。

Released: 2-Aug-2021 6:00 PM EDT
Variantes genéticas influyen sobre la reacción al tratamiento contra la migraña, dice nuevo estudio de Mayo
Mayo Clinic

Las migrañas acosan a millones de personas en todo el mundo. Sin embargo, aún es un proceso largo y complejo el identificar con precisión un medicamento profiláctico (o fármaco más frecuentemente recetado a personas diagnosticadas con migrañas) que surta efecto.

Released: 2-Aug-2021 12:20 PM EDT
UCI Receives Record $592 Million in Research Funding for Fiscal 2020-21
University of California, Irvine

Irvine, Calif., Aug. 2, 2021 — From cutting-edge research for advancing precision medicine to an innovative new effort for improving public water infrastructure to increase conservation, University of California, Irvine scholars, scientists and physicians are blazing new paths to help change the world. And their impact keeps growing.

   
Released: 29-Jul-2021 10:40 AM EDT
AMP Publishes Recommendations to Facilitate Widespread Adoption of Genetic Variant Data Sharing Practices
Association for Molecular Pathology

The Association for Molecular Pathology (AMP) today released recommendations to support and facilitate sharing of variant data through the use of public repositories.

Released: 28-Jul-2021 8:00 AM EDT
MD Anderson and Blueprint Medicines Announce Strategic Collaboration to Accelerate BLU-222 Development
University of Texas MD Anderson Cancer Center

MD Anderson and Blueprint Medicines announced a three-year strategic collaboration to accelerate the development of BLU-222, an investigational targeted therapy against CDK2.

Released: 23-Jul-2021 4:35 PM EDT
Comprehensive Clinical Sequencing Opens Door to the Promise of Precision Medicine
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient’s cancer.

Released: 22-Jul-2021 10:45 AM EDT
Rensselaer-Designed Platform Could Enable Personalized Immunotherapy
Rensselaer Polytechnic Institute (RPI)

An innovative testing platform that more closely mimics what cancer encounters in the body may allow for more precise, personalized therapies by enabling the rapid study of multiple therapeutic combinations against tumor cells. The platform, which uses a three-dimensional environment to more closely mirror a tumor microenvironment, is demonstrated in research published in Communications Biology.

Released: 19-Jul-2021 8:00 AM EDT
Personalized Immunotherapy Response Studied in Body-on-a-Chip Cancer Models
Atrium Health Wake Forest Baptist

Wake Forest researchers and clinicians are using patient-specific tumor ‘organoid’ models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer.

Released: 14-Jul-2021 4:15 PM EDT
University of Chicago Medicine Comprehensive Cancer Center Researcher Receives National Cancer Clinical Investigator Team Leadership Award
University of Chicago Medical Center

Daniel Catenacci, MD, a physician-scientist and associate professor of medicine at UChicago Medicine, has received the National Cancer Institute (NCI) 2021 Cancer Clinical Investigator Team Leadership Award (CCITLA).

Released: 8-Jul-2021 10:15 AM EDT
Precision medicine helps identify “at-risk rapid decliners” in early-stage kidney disease
Michigan Medicine - University of Michigan

A novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.

Released: 7-Jul-2021 11:45 AM EDT
How to Reduce Obesity among Latino Children, with Precision
UC San Diego Health

Researchers at UC San Diego Altman Clinical and Translational Research Institute have received $3 million to create a precision, community-based program to address specific health problems related to adverse childhood experiences that contribute to childhood obesity among Latinos.

Released: 1-Jul-2021 5:20 PM EDT
Pesquisadores da Mayo Clinic exploram abordagem personalizada para medicamentos antiobesidade
Mayo Clinic

As iniciativas de medicina individualizada se concentram principalmente nas doenças raras ou no câncer. Pouco foi tentado para individualizar o tratamento de doenças crônicas não transmissíveis, como a obesidade, uma doença crônica recorrente e uma causa primária de diabetes tipo 2, gordura hepática, doenças cardiovasculares e câncer.

Released: 1-Jul-2021 5:05 PM EDT
Investigadores de Mayo Clinic exploran método personalizado para medicamentos contra la obesidad
Mayo Clinic

Las iniciativas de la medicina personalizada se concentran, principalmente, en las enfermedades raras o en el cáncer. Han sido escasos los intentos por personalizar el tratamiento de enfermedades crónicas no contagiosas, como la obesidad, que es una afección crónica y recurrente, además de causa principal para diabetes tipo 2, hepatopatía grasa, enfermedad cardiovascular y cáncer.

Released: 1-Jul-2021 11:05 AM EDT
Newly Discovered Genetic Variants in a Single Gene Cause Neurodevelopmental Disorder
Mayo Clinic

Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with conditions that affect how the brain functions.



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