A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome.
The changes in the environment and biodiversity brought on by climate change could be responsible for increases in allergies, autoimmune diseases and autism, according to a Rutgers researcher
We may not think about it often, but our gut is home to a complex ecosystem of microorganisms that play a critical role in how we function.
New UC San Diego Dissemination and Implementation Science Center provides researchers and practitioners with the training, technical assistance, mentoring and resources needed to implement their findings in real-world settings.
A team led by UT Southwestern researchers has identified brain circuitry that plays a key role in the dysfunctional social, repetitive, and inflexible behavioral differences that characterize autism spectrum disorders (ASD). The findings, published online this week in Nature Neuroscience, could lead to new therapies for these relatively prevalent disorders.
Researchers at University of California San Diego School of Medicine are recruiting eligible children between the ages of seven and fourteen years for a Phase III clinical trial to determine whether cannabidiol (CBD) reduces severe behavior problems in children with autism spectrum disorder.
Penn State researchers have developed a new method for studying key moments in brain development.
Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have started recruiting participants for a new clinical trial to evaluate the safety, tolerability, and efficacy of a low dose of ketamine in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.
A new study from Penn Medicine lends further evidence that the social behaviors tied to autism spectrum disorders (ASD) emerge from abnormal function of sensory neurons outside the brain.
Scientists at Sanford Burnham Prebys Medical Discovery Institute and Radboud University Medical Center in the Netherlands have identified mutations in a gene called CNOT1 that affect brain development and impair memory and learning. The research, published in The American Journal of Human Genetics, also revealed that CNOT1 interacts with several known autism spectrum disorder (ASD) genes, opening new research avenues for the condition.
Dr. Laura Mead Offers Support for Parents of Children With Autism in FREEE Webinar - June 19 @ 10am, EST
A mouse study by Craig Powell, M.D., Ph.D., and colleagues suggests that early genetic rescue may be a potential therapy in autism spectrum disorder, or ASD. Powell looked at one gene called SHANK3, whose alteration is seen in about 0.5 percent of ASD patients.
School-based mindfulness programs can improve decision-making skills and teach children with autism to focus attention and react less impulsively through breathing exercises that will allow them to reduce anxiety, according to Rutgers researchers.
A UC Davis MIND Institute study found that around 30% of young children with autism have less severe autism symptoms at age 6 than they did at age 3, with some losing their autism diagnoses entirely. It also found that girls tend to show greater reduction and less rise in their autism symptom severity than boys with autism. Children with higher IQs were more likely to show a reduction in their symptoms.
Inoculation with a beneficial microorganism during pregnancy fended off an autism-like syndrome in offspring, according to a new animal study. The paper is the latest to suggest that 'good bacteria' impacts the brain.
Dr. Adrien A. Eshraghi and University of Miami Health System coauthors published a new correspondence titled COVID-19: overcoming the challenges faced by individuals with autism and their families in The Lancet Psychiatry. In this commentary, the authors address specific challenges patients with autism and their families might encounter during the pandemic, as well as what healthcare providers should know and do to ensure optimal and safe care.
The HANDS in Autism® Interdisciplinary Training & Resource Center at IUPUI launched a Coronavirus Hub for educators, families, and medical professionals to assist them in helping individuals with autism spectrum disorder cope during the pandemic.
Adolescents and young adults with autism spectrum disorder (ASD) and those with typical development show similar proactive cognitive control. However, symptoms of depression in individuals with autism were linked to less proactive control, a UC Davis study found.
A new brain imaging study of prairie voles—which are among only about 5% of mammalian species besides humans who mate for life —found that when it comes to forming bonds, longing for one another may be as important as being together. The study also sheds light on why it's so hard to social distance.
The Institute for Play Therapy Education at South Dakota State University is the first in the state to become an Association for Play Therapy-approved center.
Researchers have created 3D tissue structures that recapitulate many aspects of specific human brain regions.
Many individuals with autism spectrum disorder (ASD) struggle with finding and maintaining employment, which is an important key to helping them achieve lifelong success. To create a bridge toward employment, the Benjamin J. Geigerman Lecture Series was created at UTHealth.
Improper removal of faulty brain cells during neurodevelopment may cause lifelong behavioral issues, new research from the University of Virginia School of Medicine suggests. The finding also could have important implications for a wide range of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.
As Australia’s teachers strive to shift education online, parents everywhere are bracing for change, but no more so than parents of children with additional needs such as autism, who fear their kids may be left behind in the race to adjust.
In honor of Autism Awareness Month, ACSM partners with ACSM Certified Exercise Physiologist® to share three evidence-based teaching strategies to help get those with autism moving
As every teacher will assert, self-regulation is the key to optimal learning; it helps kids tune in, stay focussed and be ready to learn. But what if your child isn’t wired this way? For many children, self-regulation is hard to master, but for kids on the autism spectrum, it can seem insurmountable, singling them out and creating barriers to their learning.
Researchers at the Johns Hopkins Bloomberg School of Public Health contributed to a new U.S. Centers for Disease Control and Prevention report that finds the prevalence of autism spectrum disorder (ASD) among 11 surveillance sites as 1 in 54 among children aged 8 years in 2016 (or 1.85 percent).
For the eighth consecutive year, the Centers for Disease Control and Prevention finds autism prevalence increased in the United States
Expressive language sampling yielded five language-related outcome measures that may be useful for treatment studies in intellectual disabilities, especially fragile X syndrome. The measures were generally valid and reliable across the range of ages, IQs and autism symptom severity of participants. According to the study, led by UC Davis researchers and funded by NIH, the measures are also functional in supporting treatments that can improve language, providing far reaching benefits for individuals with intellectual disabilities.
A new study led by researchers at Children’s Hospital of Philadelphia (CHOP) shows that a set of simple questionnaires can help clinicians and families better evaluate the quality of life of people diagnosed with autism spectrum disorder (ASD). The newly-developed tool is designed for children, adolescents, and adults on the autism spectrum, and early findings show where clinicians can learn more about how to support the needs of autistic individuals by directly asking them these critical questions.
Wealthy, white California counties—once considered the nation’s hotbeds for autism spectrum disorder (ASD)—have seen prevalence flatten or fall in the last two decades, while rates among poor whites and minorities keep ticking up, new CU Boulder research has found.
Researchers at Johns Hopkins Bloomberg School of Public Health have demonstrated the use of stem-cell-derived “mini-brains” to detect harmful side effects of a common drug on the developing brain. Mini-brains are miniature human brain models, developed with human cells and barely visible to the human eye, whose cellular mechanisms mimic those of the developing human brain.
The UC Davis MIND Institute’s Collaborative START Lab behind three of the top 10 autism studies of 2019. The studies explore early interventions and new school transitions for children on the autism spectrum.
UCLA researchers have found that it is possible to assess a person’s ability to feel empathy by studying their brain activity while they are resting rather than while they are engaged in specific tasks.
Ever wonder how mice talk to each other? We don’t have a dictionary quite yet, but UD neuroscientist Josh Neunuebel and his lab have linked the ultrasonic vocalizations made by mice with specific behaviors. It’s a significant advance of our understanding of communication science.
Researchers found that repeats in the gene that causes Fragile X Syndrome normally regulate how and when proteins are made in neurons.
A novel research study by UC San Diego researchers will determine whether testing stored blood drops, recorded at birth, for 1,000 different molecules and chemicals can help predict autism risk years before symptoms would likely appear.
SDSC researchers used SDSC’s ‘Comet’ Supercomputer to analyze genome sequences in a recent study published in Nature Medicine by an international team of scientists led by researchers at UC San Diego School of Medicine. The study describes a method to measure disease-causing mutations found only in the sperm of the father, providing a more accurate assessment of autism spectrum disease (ASD) risk in future children.
It is not uncommon for children and teens with autism spectrum disorder to struggle with sleep. Trouble falling asleep and staying asleep or refusing to go to bed are just some of the sleep problems they can experience. To help families, neurologists and other healthcare providers make decisions on the best treatments, the American Academy of Neurology (AAN) has issued a new guideline for sleep problems in children and teens with autism, published in the February 12, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A UCLA-led study reveals a new role for a gene that’s associated with autism spectrum disorder, intellectual disability and language impairment.
Researchers at the University of New Hampshire found that the neurons involved in Pavlovian learning shift their behavior and become more synchronized when a memory is being formed – a finding that helps better understand memory mechanisms and provides clues for the development of future therapies for memory-related diseases like dementia, autism and post-traumatic stress disorder (PTSD).
Results suggest social interaction success for autistic adults revolves around partner compatibility, not just participant skill set. “If autistic people were inherently poor, you’d expect two autistic people to struggle more than an autistic and non-autistic person. That’s not what we found.”
Algorithms based on artificial intelligence do better at supporting educational and clinical decision-making, according to a new study.
Rutgers researchers have found that a test widely used to diagnose whether children have autism is less reliable than previously assumed.
With help from a prestigious National Science Foundation Career Grant, a Mississippi State faculty member is working to advance his nuclear physics research and provide a new summer school experience for Mississippi students with Autism Spectrum Disorder.
Fragile X syndrome is a debilitating genetic neurodevelopmental disorder that affects people worldwide, but many doctors don’t know anything about it, let alone have the resources to properly diagnose or treat it.
Doctors and scientists — experts in the rare and severely disabling fragile X syndrome — had arrived from the United States, including six from the UC Davis MIND Institute. They came to offer the families useful information and maybe open doors to desperately needed help in a region of the world that, until fairly recently, hardly recognized fragile X syndrome, let alone knew how to diagnose or treat it.
In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with risk for autism. The study also shows significant progress towards teasing apart the genes associated with ASD from those associated with intellectual disability and developmental delay, conditions which often overlap.
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