Newswise — Low Anterior Resection Syndrome and Quality of Life After Sphincter-Sparing Rectal Cancer Surgery
A Long-term Longitudinal Follow-up
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 14–20
doi: 10.1097/DCR.0000000000001228
Original Contributions: Colorectal Cancer
BACKGROUND: Despite low anterior resection syndrome being a well-known consequence of sphincter-preserving rectal cancer surgery, the long-term effect on bowel function and quality of life is not fully understood.
A Changing Spectrum of Colorectal Cancer Biology With Age
Implications for the Young Patient
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 21–26
doi: 10.1097/DCR.0000000000001188
Original Contributions: Colorectal Cancer
BACKGROUND: The methylator pathway of colorectal carcinogenesis, characterized by CpG island hypermethylation and BRAF mutations, accounts for ≈25% of colorectal cancers. Because these cancers tend to be right sided and because DNA methylation in the right colon increases with age, we expect an increasing proportion of right-sided cancer over time. Conversely, we expect young patients (age <50 y) to have less methylated and fewer right-sided cancers.
A Decision Analysis for Rectal-Sparing Familial Adenomatous Polyposis
Total Colectomy With Ileorectal Anastomosis Versus Proctocolectomy With IPAA
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 27–32
doi: 10.1097/DCR.0000000000001186
Original Contributions: Colorectal Cancer
BACKGROUND: There are different approaches for the surgical management of rectal-sparing familial adenomatous polyposis with variable impacts on both quality of life and survival.
Conditional Probability of Survival After Neoadjuvant Chemoradiation and Proctectomy for Rectal Cancer
What Matters and When
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 33–39
doi: 10.1097/DCR.0000000000001239
Original Contributions: Colorectal Cancer
BACKGROUND: Disease-free survival estimated from the time of surgery does not account for the changing likelihood of survival based on time already accrued. Conditional disease-free survival is defined as the probability of remaining disease free after reaching a specific time point without recurrence.
Short- and Long-term Outcomes of Minimally Invasive Versus Open Multivisceral Resection for Locally Advanced Colorectal Cancer
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 40–46
doi: 10.1097/DCR.0000000000001255
Original Contributions: Colorectal Cancer
BACKGROUND: Colorectal cancer invading the adjacent organs/structures is detected in 5% to 20% of all surgical interventions performed for the management of colorectal cancer.
Laparoscopic Ventral Rectopexy Versus Stapled Transanal Rectal Resection for Treatment of Obstructed Defecation in the Elderly
Long-term Results of a Prospective Randomized Study
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 47–55
doi: 10.1097/DCR.0000000000001256
Original Contributions: Pelvic Floor
BACKGROUND: Obstructed defecation is a common complaint in coloproctology. Many anal, abdominal, and laparoscopic procedures are adopted to correct the underlying condition.
The Contributions of Internal Intussusception, Irritable Bowel Syndrome, and Pelvic Floor Dyssynergia to Obstructed Defecation Syndrome
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 56–62
doi: 10.1097/DCR.0000000000001250
Original Contributions: Pelvic Floor
BACKGROUND: Recently, there has been a trend toward surgical management of internal intussusceptiondespite an unclear correlation with constipation symptoms.
A Quality-of-Life Comparison of Two Fecal Incontinence Phenotypes
Isolated Fecal Incontinence Versus Concurrent Fecal Incontinence With Constipation
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 63–70
doi: 10.1097/DCR.0000000000001242
Original Contributions: Pelvic Floor
BACKGROUND: Many patients with fecal incontinence report coexisting constipation. This subset of patients has not been well characterized or understood.
The Effect of Surgical Training and Operative Approach on Outcomes in Acute Diverticulitis
Should Guidelines Be Revised?
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 71–78
doi: 10.1097/DCR.0000000000001240
Original Contributions: Socioeconomic
BACKGROUND: Current guidelines accept partial colectomy and primary anastomosis with proximal diversion for select patients with perforated diverticulitis based on low-quality evidence.
Emergent Colon Resections
Does Surgeon Specialization Influence Outcomes?
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 79–87
doi: 10.1097/DCR.0000000000001230
Original Contributions: Socioeconomic
BACKGROUND: Relationships between high-volume surgeons and improved postoperative outcomes have been well documented. Colorectal procedures are often performed by general surgeons, particularly in emergent settings, and may form a large component of their practice. The influence of subspecialized training on outcomes after emergent colon surgery, however, is not well described.
C-Reactive Protein Values After Colorectal Resection
Can We Discharge a Patient With a C-Reactive Protein Value >100? A Retrospective Cohort Study
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 88–96
doi: 10.1097/DCR.0000000000001216
Original Contributions: Socioeconomic
BACKGROUND: C-reactive protein is a useful negative predictive test for the development of anastomotic leakage following colorectal surgery. Evolution of procedures (laparoscopy, enhanced recovery program, early discharge, complex redo surgery) may influence C-reactive protein values; however, this is poorly studied to date.
Effect of Medicaid Expansion on Colorectal Cancer Screening Rates
Diseases of the Colon & Rectum: January 2019 - Volume 62 - Issue 1 - p 97–103
doi: 10.1097/DCR.0000000000001260
Original Contributions: Socioeconomic
BACKGROUND: Colorectal cancer screening decreases incidence and improves survival. Minorities and low-income patients have lower screening rates. The Affordable Care Act increased insurance coverage for low-income Americans by funding Medicaid expansion. Not all states expanded Medicaid. The effect of Medicaid expansion on colorectal cancer screening is unknown.
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