New Scientific Review Demonstrates Effectiveness of Plant Fats in Combating Disease and Chronic Illness

EUGENE, OR. . . November 14, 2001 . . . .A scholarly review of the science surrounding the supplemental use of a proprietary blend of plant sterols and sterolins, Moducare(r), in preventing disease and immunological illness published this week in the prestigious medical journal, Current Opinion in Clinical Nutrition and Metabolic Care, concludes, "There is now clear evidence that these molecules [plant sterols and sterolins] can possibly be used to combat life threatening diseases where the immune system needs modulation."

Plant sterols and sterolins are essential plant fats that occur naturally in all fruits, vegetables, nuts, seeds and soy products.

Professor Patrick JD Bouic, PhD, the Head of Immunology at Stellenbosch University in Cape Town, South Africa, one of the world's leading experts on natural plant molecules having impacts on immunological responses, and author of the review article said, "Since the discovery of plant sterols in 1922, scientific research has concentrated on their cholesterol-lowering activities. There is now clear evidence that plant sterol molecules can possibly be used to combat life-threatening diseases where the immune system needs modulation such as rheumatoid arthritis, asthma, HIV and pulmonary tuberculosis.

"Optimal immune health is vital for the prevention of many chronic conditions including chronic fatigue syndrome, stress, anxiety, allergic rhinitis and sinusitis. Indeed, the role played by plant sterols in general health has been under estimated for too long," Professor Bouic said.

The review article examined validated clinical trials of using Moducare's(r) plant sterols and sterolins in the following areas:-- Pulmonary tuberculosis-- HIV-- Stress induced immune suppression-- Rheumatoid Arthritis-- Allergic rhinitis/sinusitis

"Professor Bouic noted, "The role of plant sterols and sterolins in the protection against cancer is unexplored at present. It is generally accepted that the immune surveillance mechanisms are vital for protection against the development of solid tumors. The current research suggests that a mixture of plant sterols and sterolins would play a pivotal role in this prevention of cancers. However, such studies are lacking at present."

All of the clinical studies cited in the review article used Moducare(r), a proprietary blend of plant sterols and sterolins.

Copies of the Abstract may be obtained at: A copy of the review article is available on line at:

Moducare's(r) safety and effectiveness has been extensively tested. Long-term studies involving 25,000 humans found no significant side effects. In addition, standard toxicology studies, pre-clinical testing and clinical observations have found no adverse effects. Since 1994, the results of clinical trials using Moducare(r) to investigate the effects of plant sterols and sterolins on pulmonary tuberculosis, HIV, stress induced immune suppression, rheumatoid arthritis, allergic rhinitis/sinusitis and tumor cell lines have been published in five other major medical journals including articles in the prestigious International Journal of Immunopharmacology, Cell Biology International, Aids Bulletin, International Journal of Tuberculosis and Lung Disease and The International Journal of Sports Medicine.

EPI is dedicated to providing the highest quality health products to our consumer base, and to achieving excellence in health care through our on-going commitment to research and education. EPI does not promote or sell food supplements, either in the United States or Canada, for the purpose of preventing, treating, mitigating or curing a specific disease or class of diseases. EPI does make its best effort to alert and inform the general public of significant scientific developments, which affect their health, including scientific papers about the ingredients, which are included in EPI's products. EPI includes the Moducare proprietary blend of sterols and sterolins in its food supplement products.

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Current Opinion in Clinical Nutrition and Metabolic Care, Nov-2001 (Nov-2001)