Ensemble of old and new techniques escorts ESCs to bona fide embryo-like structures

Three recent studies from the Zernicka-Goetz and Hanna groups (Amadei et al., 2022; Tarazi et al., 2022; Lau et al., 2022) report the development of mouse embryo-like structures from stem cells. Using a combination of stem cell-derived sources, they show that mouse embryo-like structures develop key features mimicking post-gastrulation embryos.