Research Alert

Article title: "Exosomes derived from induced vascular progenitor cells promote angiogenesis in vitro and in an in vivo rat hindlimb ischemia model"

Authors: Takerra K. Johnson, Lina Zhao, Dihan Zhu, Yang Wang, Yan Xiao, Babayewa Oguljahan, Xueying Zhao, Ward G. Kirlin, Liya Yin

From the authors: "The results of this work demonstrate exosomes as a novel physiological mechanism by which induced vascular progenitor cells exert their angiogenic effect. Moreover, angiogenic cargo of proteins and microRNAs may define the biological contributors in activating endothelial cells to form a new capillary plexus for ischemic vascular diseases." 

This study is highlighted as one of October’s “best of the best” as part of the American Physiological Society’s APSselect program.