Newswise — Hackensack Meridian Health Hackensack University Medical Center is pleased to announce that its hub-site affiliate, Temple University in Philadelphia, has been selected as one of 11 clinical hubs for a National Institutes of Health (NIH) emergency medicine clinical trials network.

The NIH established the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) to support the rapid implementation of high quality, large-scale clinical trials in emergency medicine. SIREN will support clinical trials aimed at improving patient outcomes for neurologic, heart, lung, blood and traumatic emergencies.

“We are proud of our five-year affiliation with Temple University in this important work and we are pleased to be invited to enroll in these significant NIH studies,” said Chinwe Ogedegbe, M.D., MPH, associate professor, Seton Hall-Hackensack Meridian School of Medicine, and section chief for Research in the Emergency and Trauma Center at Hackensack University Medical Center. “SIREN was awarded to sites that perform well in several categories, including enrollment, regulatory maintenance and research follow up.”

The Temple-SIREN clinical hub will coordinate the efforts of a large group of academic medical centers and emergency medical systems, including Hackensack University Medical Center, across Pennsylvania and New Jersey.

“Our team is enthusiastic about our continued support of NIH-funded research,” said Kevin Hewitt, M.D., interim chair, of the Department of Emergency Medicine at Hackensack University Medical Center. “We welcome the opportunity to contribute and collaborate.”

More broadly, SIREN consists of a Clinical Coordinating Center at the University of Michigan, a Data Coordinating Center at the Medical University of South Carolina, and eleven clinical centers across the country that will coordinate and conduct clinical trials in emergency department treatment and pre-hospital settings, such as the EMS system.

The trials will involve areas of emergency research from the most critical, such as heart attack and traumatic brain injury, to chronic conditions such as asthma and migraine headache, that often lead people to treatment in emergency departments.

“Temple University Hospital is a leading site for emergency care clinical trials and is proud to be selected by NIH for this innovative clinical trial network, which has the potential to change and improve practices nationwide for emergency medicine physicians treating patients with a wide variety of emergent conditions,” says Nina Gentile, M.D., professor of Emergency Medicine at the Lewis Katz School of Medicine at Temple University, and lead physician for Temple’s participation in the network. “Being one of only eleven clinical sites selected for SIREN is further confirmation of Temple’s national reputation for emergency medicine expertise.”   

About Temple Health Temple University Health System (TUHS) is a $1.8 billion academic health system dedicated to providing access to quality patient care and supporting excellence in medical education and research.   The Health System consists of Temple University Hospital (TUH), ranked among the “Best Hospitals” in the region by U.S. News & World Report; TUH-Episcopal Campus; TUH-Northeastern Campus; Fox Chase Cancer Center, an NCI-designated comprehensive cancer center;  Jeanes Hospital, a community-based hospital offering medical, surgical and emergency services; Temple Transport Team, a ground and air-ambulance company; and Temple Physicians, Inc., a network of community-based specialty and primary-care physician practices.  TUHS is affiliated with the Lewis Katz School of Medicine at Temple University, and Temple University Physicians, which is Temple Health’s physician practice plan comprised of more than 500 full-time and part-time academic physicians in 20 clinical departments.

The Lewis Katz School of Medicine (LKSOM), established in 1901, is one of the nation’s leading medical schools.  Each year, the School of Medicine educates approximately 840 medical students and 140 graduate students. Based on its level of funding from the National Institutes of Health, the Katz School of Medicine is the second-highest ranked medical school in Philadelphia and the third-highest in the Commonwealth of Pennsylvania.  According to U.S. News & World Report, LKSOM is among the top 10 most applied-to medical schools in the nation.

Temple Health refers to the health, education and research activities carried out by the affiliates of Temple University Health System (TUHS) and by the Katz School of Medicine.  TUHS neither provides nor controls the provision of health care. All health care is provided by its member organizations or independent health care providers affiliated with TUHS member organizations. Each TUHS member organization is owned and operated pursuant to its governing documents.


About Hackensack Meridian Health Hackensack University Medical Center

Hackensack Meridian Health Hackensack University Medical Center, a 775-bed nonprofit teaching and research hospital located in Bergen County, NJ, is the largest provider of inpatient and outpatient services in the state. Founded in 1888 as the county’s first hospital, it is now part of one of the largest networks in the state comprised of 33,000 team members and more than 6,500 physicians. Hackensack University Medical Center was listed as the number one hospital in New Jersey in U.S. News & World Report’s 2017-18 Best Hospital rankings - maintaining its place atop the NJ rankings since the rating system was introduced. It was also named one of the top four New York Metro Area hospitals. Hackensack University Medical Center is one of only five major academic medical centers in the nation to receive Healthgrades America’s 50 Best Hospitals Award for five or more years in a row. Becker’s Hospital Review recognized Hackensack University Medical Center as one of the 100 Great Hospitals in America 2017. The medical center is one of the top 25 green hospitals in the country according to Practice Greenhealth, and received 23 Gold Seals of Approval™ by The Joint Commission – more than any other hospital in the country. It was the first hospital in New Jersey and second in the nation to become a Magnet recognized hospital for nursing excellence; receiving its fifth consecutive designation in 2014. Hackensack University Medical Center has created an entire campus of award-winning care, including: the John Theurer Cancer Center; the Heart & Vascular Hospital; and the Sarkis and Siran Gabrellian Women’s and Children’s Pavilion, which houses the Joseph M. Sanzari Children’s Hospital and Donna A. Sanzari Women’s Hospital, which was designed with The Deirdre Imus Environmental Health Center and listed on the Green Guide’s list of Top 10 Green Hospitals in the U.S. Hackensack University Medical Center is the Hometown Hospital of the New York Giants and the New York Red Bulls and is Official Medical Services Provider to The Northern Trust PGA Golf Tournament. It remains committed to its community through fundraising and community events especially the Tackle Kids Cancer Campaign providing much needed research at the Children’s Cancer Institute housed at the Joseph M. Sanzari Children’s Hospital. To learn more, visit