Research Alert

Article title: Helicobacter pylori infection impairs chaperone-assisted maturation of Na,K-ATPase in gastric epithelium

Authors: Elizabeth A. Marcus, Elmira Tokhtaeva, Jossue L. Jimenez, Yi Wen, Bita V. Naini, Ashley N. Heard, Samuel Kim, Joseph Capri, Whitaker Cohn, Julian P. Whitelegge, Olga Vagin

From the authors: “This work provides evidence that Helicobacter pylori decreases levels of Na-K-ATPase, a vital transport enzyme, in gastric epithelia, both in acutely infected cultured cells and in chronically infected patients and animals.” 

This study is highlighted as one of May's "best of the best" as part of the American Physiological Society's APSselect program.

Journal Link: American Journal of Physiology - Gastrointestinal and Liver Physiology