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In a large study of pediatric cancer patients, researchers from Children’s Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors. The researchers found that NTRK fusions are more common in pediatric tumors and also involve a wider range of tumors than adult cancers, information that could help prioritize screening for NTRK fusions in pediatric cancer patients who might benefit from treatment with TRK inhibitors.

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AACI was invited last summer to join the Vaccine Consultation Panel (VCP) alongside other leading health and science organizations in the U.S. Through the VCP, AACI has received periodic updates on the development and distribution of COVID-19 vaccines and participated in efforts to educate the cancer center community and the general public on the importance of widespread vaccine uptake.

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Chulalongkorn University, in cooperation with the Ministry of Digital Economy and Society, will retrofit 500 old smartphones donated by Thai Samsung Electrics, Co., Ltd. with CU Smart Lens invented by Professor Sanong Akasit, Ph.D., Department of Chemistry, Faculty of Science, and turn them into microscopes. The microscopes will be donated to 500 marginal schools throughout the country as part of the “2,500 Microscopes from Old Cell Phones for Marginal Schools“ project, which supports equal opportunity in science education for all.

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Sylvester Comprehensive Cancer Center researchers are looking at ways to combine imaging and biomarkers to predict prostate cancer progression more accurately.

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The NEJM paper actually states that the efficacy between the first and second doses was found to be 52 percent when given 21 days apart. After the second dose, the efficacy raises to 95 percent.

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Chulalongkorn University launched its new Center for Social Innovation of Chulalongkorn University (CU Social Innovation Hub or CU SiHub), bringing together professors and researchers to prepare for and support the country’s sustainable development.

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A new Houston Methodist study found males are more likely to test positive for COVID-19, have complications and die from the virus than females, independent of age. The peer-reviewed observational study appears in PLOS ONE, a multidisciplinary journal published by the Public Library of Science.

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NIH Revises Treatment Guidelines for Ivermectin for the Treatment of COVID-19 Ivermectin is Now a Therapeutic Option for Doctors & Prescribers

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The Catalyst Award will be presented to Ramin Valian of Allergan, an AbbVie Company, in recognition of Allergan's ongoing leadership and commitment to the development of innovative treatments to advance glaucoma care.

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Researchers find that CRY-1, a regulator of circadian rhythms, promotes tumor progression by altering DNA repair.

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The CDC is funding a Rush-led effort in which 8 academic medical centers will track the clinical, physical and mental functioning -- including neuro-cognition and fatigue – of nearly 5000 COVID patients for two years to better assess the long-term outcomes of the disease.

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Drs. Armando Sardi, Vadim Gushchin, and Kurtis Campbell, Surgical Oncology Department at Mercy Medical Center, are regarded for their training and skills in utilizing HIPEC to treat advanced stages of abdominal cancer (peritoneal surface malignancies). New findings by a prestigious organization of clinicians adds to this reputation, placing Mercy’s program among the nation’s best.

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A new potential therapy for COVID-19 developed by researchers at Rush University Medical Center has shown success in preventing the disease’s symptoms in mice.

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Studying ancient food webs can help scientists reconstruct communities of species, many long extinct, and even use those insights to figure out how modern-day communities might change in the future. There’s just one problem: only some species left enough of a trace for scientists to find eons later, leaving large gaps in the fossil record — and researchers’ ability to piece together the food webs from the past. A new paper shines a light on those gaps and points the way to how to account for them.

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New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn’t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don’t target.

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Waldenström macroglobulinemia (WM), a rare form of lymphoma, does not have any known cure and only one FDA-approved treatment making it challenging to treat patients. Researchers at the University of New Hampshire took the novel approach of targeting specific cell proteins that control DNA information using inhibitors, or drugs, that were effective in reducing the growth of the cancer cells and when combined with a third drug were even more successful in killing the WM cancer cells which could lead to more treatment options.

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An international team of researchers has discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.

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Astronomers have catalogued 126 years of changes to HS Hydrae, a rare evolving eclipsing binary. The two stars in HS Hydrae began to eclipse each other starting around a century ago, peaking in the 1960s. The degree of eclipsing then plummeted over the course of just a half century, and will cease around Feb. 2021.

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Hubble astronomers have retraced the expanding gaseous debris from a nearby exploded star to estimate the location and time of the stellar detonation. Their analysis reveals that the light from the supernova blast reached Earth about 1,700 years ago.

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A class of undergraduate astrophysics students at the University of Chicago helped discover a galaxy that dates back to a time when the universe was only 1.2 billion years old, about one-tenth of its current age.

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S&T is working with NIST and the University of Louisville to develop guidelines to standardize Wastewater-Based Epidemiology testing methods nationwide.

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What do the 3,000-year-old actions of an Egyptian pharaoh say about how we should tackle the biggest challenges of the 21st century?

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Article displays 12 research and development highlights published by PPPL in 2020.

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Scientists can track the growing season globally for free through the NASA land surface phenology project.

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A survey of Californians finds that exposure to violence has pervasive social and emotional impacts on people, especially when firearms are involved.

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Foraging humans find food, reproduce, share parenting, and even organise their social groups in similar ways as surrounding mammal and bird species, depending on where they live in the world, new research has found.

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A new year brings a new opportunity to focus on health, and Loyola Medicine Men's Health Center Director Kevin McVary, MD is offering tips for a healthier 2021.

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Computational materials science experts at the U.S. Department of Energy’s Ames Laboratory enhanced an algorithm that borrows its approach from the nesting habits of cuckoo birds, reducing the search time for new high-tech alloys from weeks to mere seconds.

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January Snapshots: CO2 removal, water-splitting, battery mystery, thirdhand smoke remediation

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The January 6 rally that turned into riot, and the fallout and aftermath of these unprecedented events, from impeachment to the inauguration. Experts from University of Washington and others will discuss these topics and take questions from media.

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New probes allow scientists to see four-stranded DNA interacting with molecules inside living human cells, unravelling its role in cellular processes.

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A group of scientists led by the American Museum of Natural History and Bat Conservation International have discovered a new species of a striking orange and black bat in a mountain range in West Africa.

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A new computational technique that uses heat map data to reverse engineer highly detailed models of chromosomes. Through this work, researchers have uncovered new information about the close spatial relationships that chromatin folding creates between genes that can be highly distant from one another along DNA strands.

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As a new, apparently more transmissible version of the virus that causes COVID-19 has appeared in several countries, new research finds that the transmissibility of viral strains and the population density of a region will play big roles in how vaccination campaigns can help towns and cities return to more normal activities. The findings suggest that directing vaccines toward densely populated counties would help to interrupt transmission of the disease.

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A new type of stem cell - that is, a cell with regenerative abilities - could be closer on the horizon, a new study led by UNSW Sydney shows.

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The Pulmonary Fibrosis Foundation (PFF) has announced United Therapeutics' sponsorship of the PFF Registry, a research resource that tracks clinical data, blood samples and patient-reported outcomes from individuals living with pulmonary fibrosis nationwide.