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Newswise: New treatment demonstrated for people with vaccine clots
8-Jun-2021 10:50 AM EDT
New treatment demonstrated for people with vaccine clots
McMaster University

The treatment’s effectiveness was described in a report describing three Canadian patients who received the AstraZeneca vaccine, and who subsequently developed VITT. Two suffered clotting in their legs and the third had clots blocking arteries and veins inside their brain.

Released: 3-Jun-2021 1:05 PM EDT
Heavy-drinking young adults reduce problematic alcohol use early in pandemic, but young women face increased mental health burden
McMaster University

In a sample of nearly 500 young adults ranging in age from 18 to 25, researchers saw a reduction in problematic drinking and alcohol consequences during the initial phase of the pandemic for both men and women. This is in contrast to many anecdotal reports of increased drinking and increased household spending on alcohol during that time period. Additional findings showed increased rates of depression and anxiety symptoms among young women – increases that were not observed to a significant degree among male participants.

Released: 19-May-2021 12:10 PM EDT
Triple-Drug Therapy Safely Cuts Serious Asthma Flares
McMaster University

Findings are from a systematic review and meta-analysis. Data from 20 randomized controlled trials, which included a total of almost 12,000 patients, were analyzed in the study, providing strong and clear evidence in support of triple-drug therapy.

Newswise: Peatlands pose complex, poorly understood fire risk, researchers warn
Released: 18-May-2021 10:35 AM EDT
Peatlands pose complex, poorly understood fire risk, researchers warn
McMaster University

Five years after the disastrous wildfire in Fort McMurray, Alberta, researchers are warning that the complex role of peatlands, a factor critical to projecting the risk and behaviour of future fires, is missing from the forecasting model.

Newswise: Lung disease specialist takes up chair named for mentor
Released: 18-May-2021 10:15 AM EDT
Lung disease specialist takes up chair named for mentor
McMaster University

Kolb is research director at the Firestone Institute for Respiratory Health at McMaster and St. Joseph’s Healthcare Hamilton, as well as division director for respirology at the Department of Medicine. He is also the European Respiratory Journal’s chief editor.

Released: 17-May-2021 8:50 AM EDT
Stair climbing offers significant cardiovascular and muscular benefits for heart patients, researchers find
McMaster University

A team of McMaster University researchers who studied heart patients found that stair-climbing routines, whether vigorous or moderate, provide significant cardiovascular and muscular benefits.

Newswise: Preemie boys age faster as men, study shows
12-May-2021 2:15 PM EDT
Preemie boys age faster as men, study shows
McMaster University

Using an epigenetic clock, the researchers looked at the genes of 45 of those who were ELBW babies along with 47 who were normal birth weight when they were age 30 to 35 to compare their biological age, controlling for chronic health problems and sensory impairments.

Newswise: Simple surgery prevents strokes in heart patients
11-May-2021 1:40 PM EDT
Simple surgery prevents strokes in heart patients
McMaster University

The study tracked 4,811 people in 27 countries who are living with atrial fibrillation and taking blood thinners. Consenting patients undertaking cardiopulmonary bypass surgery were randomly selected for the additional left atrial appendage occlusion surgery; their outcomes compared with those who only took medicine. They were all followed for a median of four years.

Newswise: Bacteria do not colonize the gut before birth, says collaborative study
Released: 10-May-2021 12:05 PM EDT
Bacteria do not colonize the gut before birth, says collaborative study
McMaster University

Researchers examined prenatal stool (meconium) samples collected from 20 babies during breech Cesarean delivery. By including only breech caesarean deliveries in healthy pregnant women they were able to avoid the transmission of bacteria that occurs naturally during a vaginal birth.

3-May-2021 7:05 AM EDT
New guidelines for schools recommend against food bans
McMaster University

The international guideline panel included 22 health-care professionals, school administrators, and parents of children with and without food allergy, along with a team of six researchers with methodology expertise. A systematic literature review of practices for managing food allergy in schools found a lack of high-quality evidence, so the guideline recommendations are graded as conditional.

Newswise: McMaster scientists discover trained immune cells are highly effective against cancer
Released: 14-Apr-2021 5:30 PM EDT
McMaster scientists discover trained immune cells are highly effective against cancer
McMaster University

McMaster University researchers Ali Ashkar and Sophie Poznanski have uncovered that changing the metabolism of natural killer (NK) immune cells allows these cells to overcome the hostile conditions found inside tumours and destroy advanced ovarian and lung cancer.

Released: 14-Apr-2021 10:05 AM EDT
Grant accelerates McMaster University, SQI Diagnostics effort to move infection testing innovation from lab to market
McMaster University

A new grant is helping McMaster University engineers and a Toronto precision-medicine diagnostics company to get infection-testing technology to market while generating opportunities for students.

Newswise: Doctors still reluctant to prescribe medical cannabis: McMaster
12-Apr-2021 9:00 AM EDT
Doctors still reluctant to prescribe medical cannabis: McMaster
McMaster University

Ontario doctors are still hesitant to prescribe medical cannabis to patients suffering long-term pain 20 years after it was first introduced, says a new study carried out at McMaster University.

Released: 12-Apr-2021 9:00 AM EDT
Pandemic Paradox: People Want to Improve Mental Health by Exercising, but Stress and Anxiety Get in the Way, Research Shows
McMaster University

The pandemic has created a paradox where mental health has become both a motivator for and a barrier to physical activity.

1-Apr-2021 1:20 PM EDT
Are you using antihistamines properly?
McMaster University

People need to rethink what they stock in their home cabinets as allergy medicines, what hospitals keep on formulary, and what policymakers recommend. The message needs to get out. This publication is on time for the spring allergy season and as COVID vaccines roll out, for which rashes are common and antihistamines can be helpful

Released: 1-Apr-2021 12:55 PM EDT
Possible trigger for Crohn’s disease identified
McMaster University

AIEC bacteria grow in a biofilm that coats cells lining the intestinal wall, protecting them from both the immune system and antibiotics. In this research, the team identified a critical protein structure on the surface of the bacteria that allow them to grow in biofilms.

29-Mar-2021 11:50 AM EDT
Worldwide study ratifies link of processed meat to cardiovascular disease and death
McMaster University

The information comes from the diets and health outcomes of 134,297 people from 21 countries spanning five continents, who were tracked by researchers for data on meat consumption and cardiovascular illnesses. After following the participants for almost a decade, the researchers found consumption of 150 grams or more of processed meat a week was associated with a 46 per cent higher risk of cardiovascular disease and a 51 per cent higher risk of death than those who ate no processed meat. However, the researchers also found moderate levels of consumption of non-processed meats had a neutral effect on health.

Released: 23-Mar-2021 4:10 PM EDT
McMaster scientist resolves COVID-19 clot question
McMaster University

Blood from critically ill COVID-19 patients contains antibodies that can contribute to clotting. These antibodies form immune complexes that activate platelets, the cells that lead to blood clot formation. Some blood-thinner medications can block these immune complexes and potentially reduce clots.

Released: 19-Mar-2021 12:05 PM EDT
Nearly two-thirds of middle-aged and older adults in Canada report adverse childhood experiences
McMaster University

The study used data collected from 44,817 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), a large, national population-based study of health and aging. The participants completed questionnaires about adverse childhood experiences through telephone and face-to-face interviews between 2015 and 2018.

Newswise:Video Embedded how-well-does-vaccination-work-in-residents-of-long-term-care-homes
VIDEO
Released: 18-Mar-2021 10:55 AM EDT
How well does vaccination work in residents of long-term care homes
McMaster University

The study will involve more than 2,000 residents, staff, and visitors of long-term care homes in Ontario over the course of a year. Blood and saliva will be examined.

Released: 8-Mar-2021 12:50 PM EST
Study finds two servings of fish per week can help prevent recurrent heart disease
McMaster University

An analysis of several large studies involving participants from more than 60 countries, spearheaded by researchers from McMaster University, has found that eating oily fish regularly can help prevent cardiovascular disease (CVD) in high-risk individuals, such as those who already have heart disease or stroke.

Newswise: Five days of antibiotics fine for children with pneumonia
5-Mar-2021 5:30 PM EST
Five days of antibiotics fine for children with pneumonia
McMaster University

The study, involving 281 Ontario children, found that 85.7% of those who received the short course of antibiotics and 84.1% of those who received the longer course of medication were cured two to three weeks later.

Newswise: Evolution drives autism and other conditions to occur much more frequently in boys, genetic researchers say
Released: 3-Mar-2021 10:45 AM EST
Evolution drives autism and other conditions to occur much more frequently in boys, genetic researchers say
McMaster University

Evolutionary forces drive a glaring gender imbalance in the occurrence of many health conditions, including autism, a team of genetics researchers has concluded.

Newswise: Global study finds diet high in poor quality carbohydrates increases heart disease and death
22-Feb-2021 1:55 PM EST
Global study finds diet high in poor quality carbohydrates increases heart disease and death
McMaster University

A total of 137,851 people aged 35 to 70 years old were followed for a median of 9.5 years through the Population Urban and Rural Epidemiology (PURE) study run by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences.

Newswise: Researchers take early step toward leukemia drug therapy
Released: 16-Feb-2021 1:55 PM EST
Researchers take early step toward leukemia drug therapy
McMaster University

The research team has discovered that for acute myeloid leukemia (AML) patients, there is a dopamine receptor pathway that becomes abnormally activated in the cancer stem cells. This inspired the clinical investigation of a dopamine receptor-inhibiting drug thioridazine as a new therapy for patients, and their focus on adult AML has revealed encouraging results.

Released: 9-Feb-2021 11:45 AM EST
New Study to Test Drugs for Early COVID-19 Infection
McMaster University

The McMaster research team is partnering with research clinic Cardresearch and the Pontifical Catholic University of Minas Gerais in Brazil as well as the University of Stellenbosch in South Africa on an ongoing clinical trial established to answer multiple questions of drug effectiveness over time.

Newswise: Researchers find link between children’s time perception and risk for developmental coordination disorder
Released: 5-Feb-2021 8:45 AM EST
Researchers find link between children’s time perception and risk for developmental coordination disorder
McMaster University

Neuroscientists at McMaster University have found a link between children who are at risk for developmental coordination disorder (DCD), a common condition that can cause clumsiness, and difficulties with time perception such as interpreting changes in rhythmic beats.

Newswise: New immunotherapy combination shows great promise for lung cancer, McMaster researchers find
Released: 21-Jan-2021 7:00 PM EST
New immunotherapy combination shows great promise for lung cancer, McMaster researchers find
McMaster University

Researchers at Canada's McMaster University have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.

Released: 20-Jan-2021 4:50 PM EST
Treating moms with postpartum depression helps their babies’ brains
McMaster University

For the study 40 infants of women diagnosed with postpartum depression were matched with 40 infants of non-depressed mothers on infant age, gender and socioeconomic status. The mothers with postpartum depression received nine weeks of group CBT. The infants were all tested before the treatment and nine weeks later, including a questionnaire on the infant behaviour completed by the mother and her partner.

Newswise: Canadian researchers create new form of cultivated meat
Released: 19-Jan-2021 11:30 AM EST
Canadian researchers create new form of cultivated meat
McMaster University

Researchers at Canada's McMaster University have developed a new form of cultivated meat using a method that promises more natural flavour and texture than other alternatives to traditional meat from animals.

Newswise: New delivery method cuts required dose, promises relief from adverse side effects of antipsychotic medication
Released: 15-Jan-2021 10:35 AM EST
New delivery method cuts required dose, promises relief from adverse side effects of antipsychotic medication
McMaster University

A team of neuroscientists and engineers at McMaster University has created a nasal spray to deliver antipsychotic medication directly to the brain instead of having it pass through the body.

Newswise:Video Embedded researchers-use-modern-techniques-to-unravel-an-18th-century-mystery
VIDEO
Released: 12-Jan-2021 11:35 AM EST
Researchers use modern techniques to unravel an 18th century mystery
McMaster University

The mysterious death of a young, 18th century socialite has inspired a research project which could yield new information about the dangers of lead exposure.

Newswise: Discovery of 2-Million-Year-Old Stone Tools in East Africa Reveal Early Humans Could Make Plans and Adapt to Environmental Change
Released: 7-Jan-2021 10:05 AM EST
Discovery of 2-Million-Year-Old Stone Tools in East Africa Reveal Early Humans Could Make Plans and Adapt to Environmental Change
McMaster University

An international team, including Canadian researchers from the University of Calgary and McMaster University, has discovered stone tools in Tanzania dating back 2 million years, the oldest evidence of human activity in what is known as the Cradle of Humankind.

Released: 7-Jan-2021 10:00 AM EST
Perception of Palliative Care in South Asian populations
McMaster University

Funded by a McMaster University, Department of Family Medicine, Pilot Research Project Funding Grant, the observational study is one of the few person-centered palliative care studies focused on the South Asian community outside India. The results showed that seventy per cent of participants in the study had a lack of understanding of palliative care and forty-four per cent thought that palliative care went against their values and beliefs.

Newswise:Video Embedded back-to-basics-researchers-find-simple-exercises-are-a-practical-time-efficient-way-to-boost-fitness
VIDEO
Released: 4-Jan-2021 9:00 AM EST
Back to basics: Researchers find simple exercises are a practical, time-efficient way to boost fitness
McMaster University

Kinesiologists at McMaster University who examined the effectiveness of old-school physical training have found that simple bodyweight exercises, when performed vigorously over short periods, improve cardiorespiratory fitness.

Newswise: Infectious disease detectives: Researchers track and analyze smallpox epidemics over three centuries
18-Dec-2020 11:10 AM EST
Infectious disease detectives: Researchers track and analyze smallpox epidemics over three centuries
McMaster University

Researchers from McMaster University have studied and analyzed thousands of weekly records documenting the deaths of smallpox victims in London, England over the span of nearly 300 years. The analysis provides new and rare insights into the ecology of infectious disease, establishing that the time between epidemics, the size of the outbreaks, and even the season when the epidemics occurred, changed over the centuries.

Newswise: Study finds pandemic impacts retirement homes differently
Released: 14-Dec-2020 10:45 AM EST
Study finds pandemic impacts retirement homes differently
McMaster University

The study found that between March 1 and Sept 24, 2020, 92 per cent of resident and staff infections occurred at 10 per cent of retirement homes. During that time there were 172 retirement home outbreaks involving 1,045, or 1.9 per cent, of residents and 548, or 1.5 per cent) of staff. Fifty-one retirement homes had one or more of the 215 resident deaths.

Newswise: A gene mutation that protects against disease
18-Nov-2020 11:05 AM EST
A gene mutation that protects against disease
McMaster University

Called PCSK9Q152H, the mutation of the PCSK9 gene was initially thought to protect against cardiovascular diseases. Recent studies reveal that it may protect against other human illnesses, mainly liver diseases. It may allow the PCSK9Q152H mutant subjects to stay in good health and live longer, the researchers say in a study published today in the prestigious Journal of Clinical Investigation.

Newswise: Polypill along with aspirin cuts heart attacks and strokes by up to 40%: International study
12-Nov-2020 3:05 PM EST
Polypill along with aspirin cuts heart attacks and strokes by up to 40%: International study
McMaster University

The information came from the International Polycap Study 3 (TIPS-3) study which followed the participants an average of 4.6 years. The study of 5,714 people from nine countries, particularly India and the Philippines, looked at the polypill alone compared to a placebo; aspirin alone versus a placebo, and the polypill plus aspirin versus a double placebo. The men in the study were 50 or older and the women were 55 or older.

Released: 30-Oct-2020 12:40 PM EDT
Government of Canada awards $2.5M to McMaster University to support the COVID-19 border study with McMaster HealthLabs
McMaster University

McMaster University has been awarded $2.5 million from the Government of Canada to support the McMaster HealthLabs (MHL) Canadian International COVID-19 Surveillance Border Study at Toronto Pearson International Airport, being run in partnership with Air Canada and the Greater Toronto Airports Authority (GTAA).

Newswise: More turkey dinners for people with celiac disease?
21-Oct-2020 9:30 AM EDT
More turkey dinners for people with celiac disease?
McMaster University

An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet. The findings highlight the potential therapeutic value of targeting tryptophan metabolism in the gut in celiac disease to better control symptoms, despite the gluten-free diet, and accelerate intestinal healing.

Released: 20-Oct-2020 10:25 AM EDT
The biological 'record' of extremely preterm birth differs in men and women, researchers find
McMaster University

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

19-Oct-2020 4:05 PM EDT
Researchers Create a Tool That Can Pull an Elusive COVID-19 Marker From Human Blood
McMaster University

Researchers at Canada's McMaster University and SQI Diagnostics have created a surface that repels every other element of human blood except a critical indicator of infection, opening a timely window for understanding the progress of COVID-19 in individual patients.

Newswise: Scientists Find Medieval Plague Outbreaks Picked Up Speed Over 300 Years
Released: 19-Oct-2020 3:15 PM EDT
Scientists Find Medieval Plague Outbreaks Picked Up Speed Over 300 Years
McMaster University

McMaster University researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

Newswise: Researchers create hand-held device for patients to read levels of cancer biomarker in their own blood
Released: 8-Oct-2020 12:35 PM EDT
Researchers create hand-held device for patients to read levels of cancer biomarker in their own blood
McMaster University

Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.

Newswise: New research collaboration enhances primary care
Released: 30-Sep-2020 11:35 AM EDT
New research collaboration enhances primary care
McMaster University

The collaborate will bring together researchers, clinicians, educators and partners to work on issues that will address the diverse needs of our community, including bringing paramedics into subsidized housing, prison health research, indigenous teaching through art, bringing trained volunteers into the homes of older adults, studying how to reduce the number of unnecessary medications a patient takes, and more.

Newswise: International research team develops articifial lung to support pre-term babies in distress
Released: 29-Sep-2020 10:40 AM EDT
International research team develops articifial lung to support pre-term babies in distress
McMaster University

An international team led by current and former McMaster University researchers has developed an artificial lung to support pre-term and other newborn babies in respiratory distress.

Newswise: Thousands of species in a speck of soil: Researchers reveal a much richer picture of the past with new DNA recovery technique
Released: 10-Sep-2020 7:00 AM EDT
Thousands of species in a speck of soil: Researchers reveal a much richer picture of the past with new DNA recovery technique
McMaster University

Researchers at McMaster University have developed a new technique to tease ancient DNA from soil, pulling the genomes of hundreds of animals and thousands of plants – many of them long extinct – from less than a gram of sediment.

Newswise:Video Embedded mastodons-traveled-vast-distances-across-north-america-to-adapt-to-climate-change-research
VIDEO
26-Aug-2020 12:00 PM EDT
Mastodons traveled vast distances across North America to adapt to climate change: research
McMaster University

New research from an international team of evolutionary geneticists, bioinformaticians and paleontologists suggests that dramatic environmental changes accompanying the shift or melting of continental glaciers played a key role as American mastodons moved north from their southern ranges.


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