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Newswise: A gene mutation that protects against disease
18-Nov-2020 11:05 AM EST
A gene mutation that protects against disease
McMaster University

Called PCSK9Q152H, the mutation of the PCSK9 gene was initially thought to protect against cardiovascular diseases. Recent studies reveal that it may protect against other human illnesses, mainly liver diseases. It may allow the PCSK9Q152H mutant subjects to stay in good health and live longer, the researchers say in a study published today in the prestigious Journal of Clinical Investigation.

Newswise: Polypill along with aspirin cuts heart attacks and strokes by up to 40%: International study
12-Nov-2020 3:05 PM EST
Polypill along with aspirin cuts heart attacks and strokes by up to 40%: International study
McMaster University

The information came from the International Polycap Study 3 (TIPS-3) study which followed the participants an average of 4.6 years. The study of 5,714 people from nine countries, particularly India and the Philippines, looked at the polypill alone compared to a placebo; aspirin alone versus a placebo, and the polypill plus aspirin versus a double placebo. The men in the study were 50 or older and the women were 55 or older.

Released: 30-Oct-2020 12:40 PM EDT
Government of Canada awards $2.5M to McMaster University to support the COVID-19 border study with McMaster HealthLabs
McMaster University

McMaster University has been awarded $2.5 million from the Government of Canada to support the McMaster HealthLabs (MHL) Canadian International COVID-19 Surveillance Border Study at Toronto Pearson International Airport, being run in partnership with Air Canada and the Greater Toronto Airports Authority (GTAA).

Newswise: More turkey dinners for people with celiac disease?
21-Oct-2020 9:30 AM EDT
More turkey dinners for people with celiac disease?
McMaster University

An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet. The findings highlight the potential therapeutic value of targeting tryptophan metabolism in the gut in celiac disease to better control symptoms, despite the gluten-free diet, and accelerate intestinal healing.

Released: 20-Oct-2020 10:25 AM EDT
The biological 'record' of extremely preterm birth differs in men and women, researchers find
McMaster University

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

19-Oct-2020 4:05 PM EDT
Researchers Create a Tool That Can Pull an Elusive COVID-19 Marker From Human Blood
McMaster University

Researchers at Canada's McMaster University and SQI Diagnostics have created a surface that repels every other element of human blood except a critical indicator of infection, opening a timely window for understanding the progress of COVID-19 in individual patients.

Newswise: Scientists Find Medieval Plague Outbreaks Picked Up Speed Over 300 Years
Released: 19-Oct-2020 3:15 PM EDT
Scientists Find Medieval Plague Outbreaks Picked Up Speed Over 300 Years
McMaster University

McMaster University researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

Newswise: Researchers create hand-held device for patients to read levels of cancer biomarker in their own blood
Released: 8-Oct-2020 12:35 PM EDT
Researchers create hand-held device for patients to read levels of cancer biomarker in their own blood
McMaster University

Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.

Newswise: New research collaboration enhances primary care
Released: 30-Sep-2020 11:35 AM EDT
New research collaboration enhances primary care
McMaster University

The collaborate will bring together researchers, clinicians, educators and partners to work on issues that will address the diverse needs of our community, including bringing paramedics into subsidized housing, prison health research, indigenous teaching through art, bringing trained volunteers into the homes of older adults, studying how to reduce the number of unnecessary medications a patient takes, and more.

Newswise: International research team develops articifial lung to support pre-term babies in distress
Released: 29-Sep-2020 10:40 AM EDT
International research team develops articifial lung to support pre-term babies in distress
McMaster University

An international team led by current and former McMaster University researchers has developed an artificial lung to support pre-term and other newborn babies in respiratory distress.

Newswise: Thousands of species in a speck of soil: Researchers reveal a much richer picture of the past with new DNA recovery technique
Released: 10-Sep-2020 7:00 AM EDT
Thousands of species in a speck of soil: Researchers reveal a much richer picture of the past with new DNA recovery technique
McMaster University

Researchers at McMaster University have developed a new technique to tease ancient DNA from soil, pulling the genomes of hundreds of animals and thousands of plants – many of them long extinct – from less than a gram of sediment.

Newswise:Video Embedded mastodons-traveled-vast-distances-across-north-america-to-adapt-to-climate-change-research
VIDEO
26-Aug-2020 12:00 PM EDT
Mastodons traveled vast distances across North America to adapt to climate change: research
McMaster University

New research from an international team of evolutionary geneticists, bioinformaticians and paleontologists suggests that dramatic environmental changes accompanying the shift or melting of continental glaciers played a key role as American mastodons moved north from their southern ranges.

Newswise: McMaster researchers find potential to make brain cancers in children respond better to treatment
27-Aug-2020 12:40 PM EDT
McMaster researchers find potential to make brain cancers in children respond better to treatment
McMaster University

Research published today has identified a small molecule compound that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma, making these aggressive forms of cancer more responsive to therapies.The work also found the Wnt pathway, which has historically been considered cancer-promoting, to function as a cancer inhibitor in certain contexts.

Newswise: Evidence reviews support avoiding opioid prescriptions for sprains and strains: McMaster
13-Aug-2020 10:50 AM EDT
Evidence reviews support avoiding opioid prescriptions for sprains and strains: McMaster
McMaster University

Systematic reviews and meta-analyses demonstrate that opioids fail to achieve important benefits beyond alternative interventions with less harm.

Newswise: Researchers find clues to SARS-CoV-2 infection and explore why COVID-19 impacts patients differently
Released: 11-Aug-2020 8:40 AM EDT
Researchers find clues to SARS-CoV-2 infection and explore why COVID-19 impacts patients differently
McMaster University

Previously, scientists have determined that entry of SARS-CoV-2 into cells occurs through a receptor on the cell surface, known as ACE2. But the McMaster-Waterloo team has found that the ACE2 receptor is at very low levels in human lung tissue.

30-Jul-2020 10:10 AM EDT
Brace yourself: Novel experiment isolates genes that cause some people to gain muscle while others don’t
McMaster University

Researchers studying the mystery of why some weightlifters’ muscles grow much more quickly than others’ have found new answers through a novel experiment in which subjects worked out one leg and immobilized the other.

Newswise:Video Embedded malignant-cancer-diagnosed-in-a-dinosaur-for-the-first-time
VIDEO
30-Jul-2020 9:55 AM EDT
Malignant Cancer Diagnosed in a Dinosaur for the First Time
McMaster University

A collaboration led by the Royal Ontario Museum (ROM) and McMaster University has led to the discovery and diagnosis of an aggressive malignant bone cancer — an osteosarcoma — for the first time ever in a dinosaur. No malignant cancers (tumours that can spread throughout the body and have severe health implications) have ever been documented in dinosaurs previously. The paper was published August 3rd in the prestigious medical journal The Lancet Oncology.

Released: 29-Jul-2020 10:40 AM EDT
Reviews find children not major source of COVID-19, but family stress is high
McMaster University

The review found among children who were infected, transmission was traced back to community and home settings or adults, rather than amongst children within daycares or schools even in jurisdictions where schools remained open or have since reopened.

Newswise: Eradicating disease: Scientists trace and identify origin of smallpox vaccine strains used in Civil War
14-Jul-2020 8:00 AM EDT
Eradicating disease: Scientists trace and identify origin of smallpox vaccine strains used in Civil War
McMaster University

Scientists and historians working at McMaster University, the Mütter Museum and the University of Sydney have pieced together the genomes of old viruses that were used as vaccination strains during and after the American Civil War ultimately leading to the eradication of smallpox.

Newswise: McMaster and Toyota Tsusho Canada, Inc. collaborate to move pathogen-detecting food wrap from lab to market
Released: 13-Jul-2020 12:10 PM EDT
McMaster and Toyota Tsusho Canada, Inc. collaborate to move pathogen-detecting food wrap from lab to market
McMaster University

Toyota Tsusho Canada, Inc. (“TTCI”) will team up with McMaster engineers and biochemists to move a promising new food-safety technology from the lab to the marketplace.

Released: 8-Jul-2020 2:55 PM EDT
Therapy delivered electronically more effective than face to face: Hamilton researchers
McMaster University

Based on randomized control trials, the systematic review and analysis revealed that cognitive behavioural therapy that connected therapists and patients through such modes as web-based applications, video-conferencing, email and texting, improved patients’ symptoms better than face to face when measured using standardized mood symptoms scales. As well, there was no difference in the level of satisfaction or function between the two methods of delivery.

Newswise: The science of sound: Researchers suggest use of artificial tones in perception experiments could be missing the mark
Released: 7-Jul-2020 10:35 AM EDT
The science of sound: Researchers suggest use of artificial tones in perception experiments could be missing the mark
McMaster University

Researchers at McMaster University who study how the brain processes sound have discovered the common practice of using artificial tones in perception experiments could mean scientists are overlooking important and interesting discoveries in the field of brain research

Newswise: Cave divers unlock mysteries of the earliest Americans
3-Jul-2020 2:05 PM EDT
Cave divers unlock mysteries of the earliest Americans
McMaster University

A team of underwater cave explorers in Mexico have made unprecedented archeological discoveries in some of the most inaccessible places on Earth that unlock key mysteries about the earliest inhabitants of the Western Hemisphere, according to international experts who have studied the sites.

Released: 11-Jun-2020 8:05 AM EDT
Time-Saving High-Intensity Workouts Can Benefit People with Spinal Cord Injuries, Researchers Find
McMaster University

Research from the Department of Kinesiology at McMaster University has found that the practical advantages of high-intensity interval training (HIIT), or short bursts of all-out exercise, could be especially beneficial for people who have experienced spinal cord injuries (SCI).

Released: 9-Jun-2020 7:00 AM EDT
Heat and humidity battle sunshine for influence over the spread of COVID-19, researchers find
McMaster University

An international team of researchers led by McMaster University has found that while higher heat and humidity can slow the spread of COVID-19, longer hours of sunlight are associated with a higher incidence of the disease, in a sign that sunny days can tempt more people out even if this means a higher risk of infection.

Newswise: Evidence supports physical distancing, masks, and eye protection to help prevent COVID-19
1-Jun-2020 1:30 PM EDT
Evidence supports physical distancing, masks, and eye protection to help prevent COVID-19
McMaster University

he systematic review was conducted by a large, international collaborative of researchers, front-line and specialist clinicians, epidemiologists, patients, public health and health policy experts of published and unpublished literature in any language.

Newswise: Patients still not telling MDs about use of natural health products
Released: 28-May-2020 2:50 PM EDT
Patients still not telling MDs about use of natural health products
McMaster University

The research team conducted the patient survey between November 2018 and February 2019 at the Robert Schad Naturopathic Clinic in Toronto. Based on 277 completed questionnaires, 99 per cent of the patients surveyed were using natural health products, and 46 per cent were using natural health products and prescription medications concurrently. Of those using natural health products, 42 per cent did not disclose use to their primary care physician.

Newswise: Treatment shows promise in treating deadly brain cancer
25-May-2020 8:55 AM EDT
Treatment shows promise in treating deadly brain cancer
McMaster University

In this study, researchers investigated if specific targeting of CD133+ glioblastoma with cutting-edge immunotherapy drugs could eradicate the most aggressive subpopulation of cells in the tumour. They also looked at the safety of CD133-targeting therapies on normal, non-cancerous human stem cells including hematopoietic stem cells which create blood cells and progenitor cells which can form one or more kinds of cells.

Newswise: Scientists see through glass frogs’ translucent camouflage
21-May-2020 10:25 AM EDT
Scientists see through glass frogs’ translucent camouflage
McMaster University

Glass frogs are well known for their see-through skin but, until now, the reason for this curious feature has received no experimental attention.

Newswise: Evidence shows cloth masks may help against COVID-19
Released: 25-May-2020 8:55 AM EDT
Evidence shows cloth masks may help against COVID-19
McMaster University

The international research team examined a century of evidence including recent data, and found strong evidence showing that cloth and cloth masks can reduce contamination of air and surfaces.

Newswise: Global study finds women less likely to have heart disease – and die of it – than men
19-May-2020 2:05 PM EDT
Global study finds women less likely to have heart disease – and die of it – than men
McMaster University

The information came from the Prospective Urban Rural Epidemiological (PURE) study which followed the participants an average of 10 years.

Newswise: McMaster chemists develop foolproof new test to track the fats we eat
Released: 15-May-2020 10:10 AM EDT
McMaster chemists develop foolproof new test to track the fats we eat
McMaster University

A team of researchers at McMaster University has developed a reliable and accurate blood test to track individual fat intake, a tool that could guide public health policy on healthy eating.

Newswise: Researchers find one-two punch may help fight against Salmonella
13-May-2020 12:35 PM EDT
Researchers find one-two punch may help fight against Salmonella
McMaster University

Researchers found that co-administering dephostatin and colistin in mice with a lethal Salmonella infection significantly prolonged animal survival and used a lower concentration of colistin than is normally required for treatment, thereby reducing its toxic effect.

Newswise: Yes, inflammatory bowel disease and celiac disease are linked
11-May-2020 12:35 PM EDT
Yes, inflammatory bowel disease and celiac disease are linked
McMaster University

A systematic review and meta-analysis has determined there is a nine-fold increased risk of having IBD for patients with a previous diagnosis of celiac disease. Similarly, the risk for celiac disease is increased in IBD patients, though to a smaller extent.

Released: 11-May-2020 12:30 PM EDT
Evaporating northern bogs threaten to intensify fires and global warming
McMaster University

A group of 59 international scientists, led by researchers at Canada’s McMaster University, has uncovered new information about the distinct effects of climate change on boreal forests and peatlands, which threaten to worsen wildfires and accelerate global warming.

Newswise: Canadian Chiropractors Remove Vaccination Info on Websites After Media Coverage
Released: 5-May-2020 11:05 AM EDT
Canadian Chiropractors Remove Vaccination Info on Websites After Media Coverage
McMaster University

The research team conducted a prospective cohort study focused on Canadian chiropractors’ websites between July 2016 and April 2019. Researchers revisited all identified websites from 2016 in April 2019 to explore changes to posted vaccination material.

Newswise: Potato power: Spuds serve high quality protein that’s good for women’s muscle
Released: 5-May-2020 8:00 AM EDT
Potato power: Spuds serve high quality protein that’s good for women’s muscle
McMaster University

Researchers from McMaster University have found that the potato, primarily known as a starchy vegetable, can be a source of high-quality protein that helps to maintain muscle.

Newswise: Genetic complexity: A spanner in the works?
Released: 4-May-2020 1:15 PM EDT
Genetic complexity: A spanner in the works?
McMaster University

The promise of personalized medicine has not fully materialized, say two McMaster researchers, because the full sophistication of the genetic blueprint has a more complex and far-reaching influence on human health than scientists had first realized.

Newswise:Video Embedded new-guideline-on-treating-covid-19
VIDEO
Released: 29-Apr-2020 1:35 PM EDT
New guideline on treating COVID-19
McMaster University

An international team of physicians, pharmacists, medical researchers and patient partners has developed a clinical guideline for the treatment of patients with coronavirus disease 2019 (COVID-19), published in CMAJ (Canadian Medical Association Journal).

Newswise: Website launched to support families of children affected by diabetes during COVID-19
Released: 27-Apr-2020 5:05 PM EDT
Website launched to support families of children affected by diabetes during COVID-19
McMaster University

The website addresses the need for credible information and a plan to support families with children at home. Health care providers, graduate, and undergraduate students quickly developed a website that serves as a comprehensive single source for high quality COVID-19 customized for families who have a child living with diabetes.

Newswise: Move it or lose it: Sitting around while avoiding COVID-19 creates other health risks, warns exercise researcher
Released: 23-Apr-2020 10:55 AM EDT
Move it or lose it: Sitting around while avoiding COVID-19 creates other health risks, warns exercise researcher
McMaster University

Prolonged pandemic-related isolation, physical distancing and workplace closures are leading a McMaster University researcher to raise concern over the health impacts of inactivity.

Released: 21-Apr-2020 2:05 PM EDT
$1M to study treatment for first responders with PTSD
McMaster University

The randomized control trial will focus on the effectiveness of a cognitive remediation strategy called Goal Management Training that is aimed at improving cognitive functioning among PSP with PTSD. Researchers will examine changes in everyday functional outcomes, like the ability to return to work, but also in brain structure and brain function using magnetic resonance imaging (MRI).

Newswise: Researchers predict menopause will start later and possibly disappear as parents have kids later
16-Apr-2020 2:50 PM EDT
Researchers predict menopause will start later and possibly disappear as parents have kids later
McMaster University

As mothers continue having children later in life, it is inevitable that menopause will be delayed, and possibly cease to exist altogether, say researchers at McMaster University.

Newswise: McMaster University researchers closing in on home test for COVID-19
Released: 13-Apr-2020 11:40 AM EDT
McMaster University researchers closing in on home test for COVID-19
McMaster University

McMaster University researchers are racing to create a home-based COVID-19 testing kit, which could potentially be ready to move forward for approvals and manufacturing within months.

Newswise: McMaster researchers rally to help Canadian company expedite new mask to meet urgent COVID-19 demand
Released: 8-Apr-2020 10:50 AM EDT
McMaster researchers rally to help Canadian company expedite new mask to meet urgent COVID-19 demand
McMaster University

Engineering and medical researchers at McMaster University have been racing to assist Woodbridge Foam Corporation in getting a new made-in-Canada mask designed, tested and certified, as supplies of existing medical masks become less certain.

Released: 6-Apr-2020 12:45 PM EDT
Surgical masks good for most COVID-19 treatment: McMaster
McMaster University

The N95 respirator masks should be preserved for health-care workers involved in inserting breathing tubes for patients with COVID-19. More common medical masks are fine for all other COVID-19 treatment, says preliminary research from McMaster University.

Newswise: New guidelines on caring for ICU patients with COVID-19
Released: 1-Apr-2020 1:05 PM EDT
New guidelines on caring for ICU patients with COVID-19
McMaster University

An international team including McMaster University researchers has come together to issue guidelines for health-care workers treating intensive care unit (ICU) patients with COVID-19.

Newswise: McMaster professor seeks independent agency to tackle abuse in elite youth sport
16-Mar-2020 3:40 PM EDT
McMaster professor seeks independent agency to tackle abuse in elite youth sport
McMaster University

The author calls for the establishment of an independent international safeguarding agency for sports to handle athlete disclosures, investigate and process allegations, and to support victims of abuse. The expertise developed could then be used for preventive efforts. This agency would have to have sufficient cash and clout to be effective.

Newswise: Bacteria potentially involved in the development of type 2 diabetes
6-Mar-2020 1:10 PM EST
Bacteria potentially involved in the development of type 2 diabetes
McMaster University

blood and tissue samples from 40 patients suffering from severe obesity taken during bariatric surgery were used. Half of the participants suffered from type 2 diabetes, while the other subjects showed insulin resistance without being diabetic. The researchers identified the bacterial genetic material in each of the tissues sampled, which came from the liver and three abdominal fat deposits. Based on the type of bacteria present and their relative abundance, the researchers were able to determine the bacterial signature for each tissue.


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