Early Life Exposure to Nicotine: Postnatal Neurobehavioral and Metabolic Outcomes and the Development of Childhood CancersSociety of Toxicology
Published in this month’s edition of Toxicological Sciences are articles on biotransformation, toxicokinetics, and pharmacokinetics; developmental and reproductive toxicology; nanotoxicology; and more.
This month’s issue of Toxicological Sciences offers cutting-edge toxicological research in many areas. It includes special features as well as research in developmental and reproductive toxicology; emerging technologies, methods, and models; immunotoxicology; and more.
During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.
The April 2020 issue of the Society of Toxicology’s official journal, Toxicological Sciences, features leading research in toxicology, including several manuscripts covering emerging technologies, methods, and models.
The March 2020 issue of Toxicological Sciences features leading research in toxicology, covering investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.
With 80+ Featured and Scientific Sessions and 2,000+ presentations showcasing advances in fundamental and translational sciences and emerging disciplines and technologies, the 59th Annual Meeting and ToxExpo of the Society of Toxicology is the largest forum for toxicological research in the world.
The February 2020 issue of Toxicological Sciences includes cutting-edge research spanning the toxicological field, from molecular, biochemical, and systems toxicology and nanotoxicology to regulatory science, risk assessment, and decision-making.
In addition to research exploring such areas as biomarkers, nano- and neurotoxicology, and developmental and reproductive toxicology, the January 2020 issue of Toxicological Sciences features a new article category, ToxPoint, to underscore cutting-edge topics in toxicology.
The Society of Toxicology (SOT) is pleased to announce the 2020 SOT award recipients. This year’s honorees come from a variety of backgrounds, educational experiences, and career paths and are recognized for their immense contributions to toxicology.
The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.
Toxicological Sciences continues to deliver cutting-edge research in toxicology in the November 2019 issue. This issue features research on computational toxicology and databases, developmental and reproductive toxicology, and more.
Papers on the epigenetic changes to mouse livers induced by a specific ligand and prenatal dexamethasone exposure-induced alterations in neurobehavior in female rat offspring are featured in latest issue of Toxicological Sciences.
Papers on the relationship between endocrine and renal findings in γ-secretase inhibitor Avagacestat studies and environmental exposure to phthalates during prostate development in rats are featured in latest issue of Toxicological Sciences.
The SOT 2019–2020 Presidential Chain has released a statement in response to the US EPA Memorandum released on September 10, 2019, with the Subject Line “Directive to Prioritize Efforts to Reduce Animal Testing.”
Papers on assessing drug-induced long QT using stem-cell derived cardiomyocytes and measuring sensitivity to inhibition of CYP19 activity in freshwater fish are featured in latest issue of Toxicological Sciences.
Papers on current concepts in natural killer cell biology; the role of copper in Alzheimer’s disease; how sulfane sulfur may act as a defense against electrophilic stress, assessing the proarrhythmic potential of drugs, and more are featured in latest issue of Toxicological Sciences.
Papers on dieldrin and disrupted DNA methylome, novel ach’ase reactivators, developmental neurotoxicity screening, and sex effects in ozone-mediated airway dysfunction are featured in latest issue of Toxicological Sciences.
Editor’s Highlights include papers on CRISPR screening, predicting renal toxicity, PAHs and endocrine effects on testicular gap junctions, and vincristine-induced atresia in ovarian follicles
Papers on transgenerational effects of metals; optimizing toxicity models; and thyroid deionidase screening are featured in latest issue of Toxicological Sciences.
Papers on nuclear receptor function in zebrafish; and whether PCB 95 and dendritic arborization effects are sex-dependent are featured in latest issue of Toxicological Sciences.
Taking place, March 10–14, 2019, in Baltimore, Maryland, the meeting's scientific program represents the breadth and depth of the toxicological field and includes more than 100 Featured Sessions, Scientific Sessions, and Continuing Education courses and more than 2,100 individual presentations.
Papers on developmental Nrf2 regulation by AHR in zebrafish; in vitro mechanistic assays and drug hepatotoxicity; and concentrated ambient particles and TRPA1 are featured in latest issue of Toxicological Sciences.
Description: Papers on CAR and xenobiotic metabolism; HTS for in vitro and in vivo testing; and graphene derivative toxicity featured in latest issue of Toxicological Sciences.
The Society of Toxicology (SOT) is pleased to announce the recipients of its 2019 awards. The awardees include early-career scientists to groundbreaking researchers who have impacted the field for many years.
Description: Papers on BPA and phthalates; EDCs and obesity; air pollution; respiratory outcomes in deployed soldiers; and miRNAs featured in latest issue of Toxicological Sciences.
Description: Papers on inflammasomes and Parkinson’s disease; gas extraction and amphibian health; SeqAPASS; and androgen receptor HTS featured in latest issue of Toxicological Sciences.
Description: Papers on carcinogenesis; organophosphate flame retardants and zebrafish behavior; AHR gene targeting and hepatotoxicity; nontoxic substructures; and genistein and type 1 diabetes featured in latest issue of Toxicological Sciences.
Papers on stem cell methods and models in toxicology; comparative toxicogenomics and AOPs; machine vs. animal models; pesticides and asthma; and estimating risk without animals featured in latest issue of Toxicological Sciences.
Papers on nephrotoxicity, nanomaterial genotoxicity, machine learning; arsenic and telomere length in children; iPSC-derived cardiomyoctes for drug safety studies; and asthma, air pollution, and immunity featured in latest issue of Toxicological Sciences
Air pollution; thorax toxicology; PBPK modeling of antibiotics in dairy cattle; PCBs & steatohepatitis; uranium mine particles & cardiopulmonary toxicity; green plasticizers & reproductive health; and antiandrogenic mixtures & male reproduction featured in latest issue of Toxicological Sciences
Copper exposure’s link Alzheimer’s disease, the effects of consumer microbials on the colon, a potential prostate-based activation of a carcinogen in cooked meat, and the impact of hydraulic fracturing mixtures on the immune system featured in latest issue of Toxicological Sciences.
New Toxicological Sciences features a historical perspective and contemporary review of zebrafish as a model in toxicology. There also are highlighted papers on dietary intervention for pulmonary injury; PBPK modeling for PFOA risk; IVIVE and toxicokinetics; and microelectrode arrays and seizures.
Articles on personal care product chemicals; PBPK modeling; 2D vs 3D for drug-induced liver injury; zebrafish and drug discovery; glutathione restoration and acetaminophen; high-throughput screening for thyroid hormone T4; and genetically engineered food crops featured in new Toxicological Sciences.
The Toxicological Sciences 20th anniversary celebration continues with articles on mitochondrial toxicity and organophosphorus compounds, in addition to featured papers on metabolic syndrome; paternal exposures and offspring’s mitochondria; data fusion and AOPs; DNA damage assay predictability; and imaging mammary epithelial organoids.
Despite a worldwide increase in individuals aged 60 or older, few issues in toxicological science associated with the aging process have been addressed, and the elderly remain a largely understudied, vulnerable population. SOT hosting meeting to discuss research and issues related to this topic.
With more than 6,500 individuals from around the world in attendance, the Society of Toxicology (SOT) 57th Annual Meeting and ToxExpo will feature leading experts from across the broad range of disciplines and specialties that inform and advance toxicology.
Through its awards, SOT honors more than two dozen groundbreaking scientists, emerging leaders, postdoctoral researchers, and graduate students who are advancing the science of toxicology. The SOT Awards also recognize the contributions of educators and science communicators as they work to encourage students to pursue STEM careers and improve public understanding of the connection between scientific research and public health.
The Society of Toxicology (SOT) has approved a new Issue Statement on the issues and complexities associated with understanding the health risk from low-level arsenic exposure.
The Society of Toxicology (SOT) has approved a new Issue Statement on food and feed safety related to genetically engineered (GE) crops (commonly referred to as GMOs). The Society's journal, Toxicological Sciences, also has published a new forum article that provides an in-depth review of 20+ years of GE research.
Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.
The October 2017 issue of Toxicological Sciences (Vol. 159, Issue 2) includes a wide range of articles on topics representing the latest in toxicological research and advances.
Scientific research and publishing over the past decade has experienced some substantial transformations—and not in a good way. With an increasing number of poor-quality scientific journals appearing in the marketplace, it is important to know how to recognize potential scams.
With increasing reports of and concerns about opioid abuse, there are actions toxicologists can take to help prevent and treat the problem.
A rise in caloric consumption combined with a decrease in physical activity has contributed to a boom of metabolic diseases, such as type 2 diabetes mellitus and cardiovascular diseases (e.g., heart failure and stroke).
The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.
The 2017 SOT Awards recipients have studied the role of pesticide exposure on neurodegenerative diseases, connections between chemicals and the susceptibility to allergies and asthma, risk assessment, alternative test methods and strategies, and more, in their efforts to improve public, animal and environmental health.
Toxicologists who research health, exposure-related disease, and susceptibility are actually concurrently studying the consequences of epigenetic regulation, which is why an understanding of toxicoepigenetics is so important.
There generally are two approaches used to indirectly assess proarrhythmic risk, but some researchers believe that human induced pluripotent stem-cell derived (hiPSC)-cardiomyocytes offer an opportunity to change the paradigm.