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Released: 21-Jul-2020 12:40 PM EDT
Next-Generation Risk Assessment, Antimicrobials, and More Featured in July 2020 Toxicological Sciences
Society of Toxicology

Published in this month’s edition of Toxicological Sciences are articles on biotransformation, toxicokinetics, and pharmacokinetics; developmental and reproductive toxicology; nanotoxicology; and more.

Released: 5-Jun-2020 10:50 AM EDT
Brain Barrier Systems, Murine Acetaminophen Hepatotoxicity, and More Featured in June 2020 Toxicological Sciences
Society of Toxicology

This month’s issue of Toxicological Sciences offers cutting-edge toxicological research in many areas. It includes special features as well as research in developmental and reproductive toxicology; emerging technologies, methods, and models; immunotoxicology; and more.

Released: 7-May-2020 1:50 PM EDT
Xenobiotic Receptor Activation, CRISPR/Cas9, Magnetic Resonance-Guided Radiotherapy, and More Featured in May 2020 Toxicological Sciences
Society of Toxicology

During these difficult times, the Society of Toxicology’s official journal, Toxicological Sciences, remains a source for leading research in toxicology, including in the areas of biomarkers, carcinogenesis, and organ-specific toxicology.

Released: 30-Mar-2020 4:50 PM EDT
Read-Across of Chemical Hepatotoxicants; Exposure-Based Cholinergic Synaptic Functional Deficits; and More Featured in April 2020 Toxicological Sciences
Society of Toxicology

The April 2020 issue of the Society of Toxicology’s official journal, Toxicological Sciences, features leading research in toxicology, including several manuscripts covering emerging technologies, methods, and models.

Released: 5-Mar-2020 9:40 AM EST
Vinyl Chloride, Nerve Growth Factor, Chemical Warfare, and More Examined in March 2020 Toxicological Sciences
Society of Toxicology

The March 2020 issue of Toxicological Sciences features leading research in toxicology, covering investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.

Released: 12-Feb-2020 12:30 PM EST
Toxicological Research on E-cigarettes, PFAS, Cannabinoids, Wildfires, and More to Be Presented during the SOT 59th Annual Meeting and ToxExpo
Society of Toxicology

With 80+ Featured and Scientific Sessions and 2,000+ presentations showcasing advances in fundamental and translational sciences and emerging disciplines and technologies, the 59th Annual Meeting and ToxExpo of the Society of Toxicology is the largest forum for toxicological research in the world.

Released: 4-Feb-2020 4:35 PM EST
Serum Biomarkers, Metabolite Indicators for Kidney Toxicity, Estrogenic Compound Screening, and More Featured in February 2020 Toxicological Sciences
Society of Toxicology

The February 2020 issue of Toxicological Sciences includes cutting-edge research spanning the toxicological field, from molecular, biochemical, and systems toxicology and nanotoxicology to regulatory science, risk assessment, and decision-making.

Released: 8-Jan-2020 11:35 AM EST
Tissue-Engineering, Estrogenic Chemical–Induced Responses, and Life-Stage Physiologically Based Pharmacokinetic Modeling Featured in January 2020 Toxicological Sciences
Society of Toxicology

In addition to research exploring such areas as biomarkers, nano- and neurotoxicology, and developmental and reproductive toxicology, the January 2020 issue of Toxicological Sciences features a new article category, ToxPoint, to underscore cutting-edge topics in toxicology.

Released: 12-Dec-2019 5:05 PM EST
Scientists at the Forefront of Disease Etiology, Endocrine Disruption, Risk Assessment, and More Recognized with 2020 SOT Awards
Society of Toxicology

The Society of Toxicology (SOT) is pleased to announce the 2020 SOT award recipients. This year’s honorees come from a variety of backgrounds, educational experiences, and career paths and are recognized for their immense contributions to toxicology.

Released: 4-Dec-2019 8:15 AM EST
Articles on Chronic Hexavalent Chromium Exposure, Titanium Dioxide Nanoparticles, and Bisphenol A Featured in December 2019 Toxicological Sciences
Society of Toxicology

The December 2019 issue of Toxicological Sciences features research on the leading edge of toxicology, including in the areas of carcinogenesis, developmental and reproductive toxicology, and more.

Released: 1-Nov-2019 9:50 AM EDT
Cyp2F2-Mediated Lung Cancer, Rapid Risk Assessment of Color Additives, and More Featured in November 2019 Toxicological Sciences
Society of Toxicology

Toxicological Sciences continues to deliver cutting-edge research in toxicology in the November 2019 issue. This issue features research on computational toxicology and databases, developmental and reproductive toxicology, and more.

Released: 1-Oct-2019 3:05 PM EDT
Mechanisms of Chronic Fialuridine Hepatotoxicity; Comparison of Models for Predicting Cardiotoxicity in Humans; and More Featured in October 2019 Toxicological Sciences
Society of Toxicology

Papers on the epigenetic changes to mouse livers induced by a specific ligand and prenatal dexamethasone exposure-induced alterations in neurobehavior in female rat offspring are featured in latest issue of Toxicological Sciences.

Released: 13-Sep-2019 11:00 AM EDT
Polycyclic Aromatic Hydrocarbon Exposure in Chimney Sweeps; Disruption of Lipid Homeostasis in Neonatal Mouse Brains; and More Featured in September 2019 Toxicological Sciences
Society of Toxicology

Papers on the relationship between endocrine and renal findings in γ-secretase inhibitor Avagacestat studies and environmental exposure to phthalates during prostate development in rats are featured in latest issue of Toxicological Sciences.

Released: 11-Sep-2019 5:00 PM EDT
SOT Statement on the US EPA Memorandum “Directive to Prioritize Efforts to Reduce Animal Testing”
Society of Toxicology

The SOT 2019–2020 Presidential Chain has released a statement in response to the US EPA Memorandum released on September 10, 2019, with the Subject Line “Directive to Prioritize Efforts to Reduce Animal Testing.”

Released: 1-Aug-2019 5:05 PM EDT
Role of TGFβ1 Receptor Antagonist in Mice; Genes for AHR Receptor-Dependent Induction of CYP1A1; and More Featured in August 2019 Toxicological Sciences
Society of Toxicology

Papers on assessing drug-induced long QT using stem-cell derived cardiomyocytes and measuring sensitivity to inhibition of CYP19 activity in freshwater fish are featured in latest issue of Toxicological Sciences.

Released: 1-Jul-2019 11:05 PM EDT
Copper-Induced Upregulation of microRNAs; ahr2 and Cardiotoxicity; and Natural Killer Cells Explored in July 2019 ToxSci
Society of Toxicology

Papers on current concepts in natural killer cell biology; the role of copper in Alzheimer’s disease; how sulfane sulfur may act as a defense against electrophilic stress, assessing the proarrhythmic potential of drugs, and more are featured in latest issue of Toxicological Sciences.

Released: 6-Jun-2019 3:05 PM EDT
Importance of Reproducibility in Science; Dieldrin and Disrupted DNA Methylome; Novel Ach’ase Reactivators; and More Featured in June 2019 Toxicological Sciences
Society of Toxicology

Papers on dieldrin and disrupted DNA methylome, novel ach’ase reactivators, developmental neurotoxicity screening, and sex effects in ozone-mediated airway dysfunction are featured in latest issue of Toxicological Sciences.

Released: 8-May-2019 2:05 PM EDT
CRISPR Screening and Acetaldehyde Tolerance; Systems Toxicology for Predicting Renal Toxicity; and More Featured in May 2019 Toxicological Sciences
Society of Toxicology

Editor’s Highlights include papers on CRISPR screening, predicting renal toxicity, PAHs and endocrine effects on testicular gap junctions, and vincristine-induced atresia in ovarian follicles

Released: 3-Apr-2019 5:05 PM EDT
2018 Papers of the Year; Macrophages in Lung Injury and Fibrosis; Ozone Exposure and Implantation; and More Featured in April 2019 Toxicological Sciences
Society of Toxicology

Papers on transgenerational effects of metals; optimizing toxicity models; and thyroid deionidase screening are featured in latest issue of Toxicological Sciences.

Released: 5-Mar-2019 5:05 PM EST
Zinc Oxide Nanoparticles and Alternative Splicing; 3D GI Models for Predicting Drug-Induced Diarrhea; and More Featured in March 2019 Toxicological Sciences
Society of Toxicology

Papers on nuclear receptor function in zebrafish; and whether PCB 95 and dendritic arborization effects are sex-dependent are featured in latest issue of Toxicological Sciences.

Released: 13-Feb-2019 10:00 AM EST
Society of Toxicology 58th Annual Meeting and ToxExpo Features Latest in Toxicological Research and Technology
Society of Toxicology

Taking place, March 10–14, 2019, in Baltimore, Maryland, the meeting's scientific program represents the breadth and depth of the toxicological field and includes more than 100 Featured Sessions, Scientific Sessions, and Continuing Education courses and more than 2,100 individual presentations.

Released: 11-Feb-2019 4:55 PM EST
Predicting Drug Safety; Integrating Mechanistic Data in Assessment of Carcinogens; All-Trans Retinoic Acid and Fetal Testicular Development; and More Featured in February 2019 Toxicological Sciences
Society of Toxicology

Papers on developmental Nrf2 regulation by AHR in zebrafish; in vitro mechanistic assays and drug hepatotoxicity; and concentrated ambient particles and TRPA1 are featured in latest issue of Toxicological Sciences.

Released: 8-Jan-2019 5:05 PM EST
NTP Neurotoxicology Screening Strategies Initiative; Drivers of Smoke Neurotoxicity; and More Featured in January 2019 Toxicological Sciences
Society of Toxicology

Description: Papers on CAR and xenobiotic metabolism; HTS for in vitro and in vivo testing; and graphene derivative toxicity featured in latest issue of Toxicological Sciences.

Released: 20-Dec-2018 5:00 PM EST
Scientists at the Forefront of Alternative Toxicological Methods, Pharmaceutical Safety, the Effects of Environmental Exposures on Genetics, and More Recognized with 2019 SOT Awards
Society of Toxicology

The Society of Toxicology (SOT) is pleased to announce the recipients of its 2019 awards. The awardees include early-career scientists to groundbreaking researchers who have impacted the field for many years.

Released: 4-Dec-2018 6:05 PM EST
Bisphenol A (BPA) and Phthalates; miRNAs and Nephrotoxicity; and More Featured in December 2018 Toxicological Sciences
Society of Toxicology

Description: Papers on BPA and phthalates; EDCs and obesity; air pollution; respiratory outcomes in deployed soldiers; and miRNAs featured in latest issue of Toxicological Sciences.

Released: 2-Nov-2018 4:05 PM EDT
Inflammasomes and Parkinson’s Disease; Androgen Receptor High-Throughput Screening; and More Featured in November 2018 Toxicological Sciences
Society of Toxicology

Description: Papers on inflammasomes and Parkinson’s disease; gas extraction and amphibian health; SeqAPASS; and androgen receptor HTS featured in latest issue of Toxicological Sciences.

Released: 8-Oct-2018 5:05 PM EDT
Carcinogenesis, Organophosphate Flame Retardants and Zebrafish Behavior, and More Featured in October 2018 Toxicological Sciences
Society of Toxicology

Description: Papers on carcinogenesis; organophosphate flame retardants and zebrafish behavior; AHR gene targeting and hepatotoxicity; nontoxic substructures; and genistein and type 1 diabetes featured in latest issue of Toxicological Sciences.

Released: 4-Sep-2018 4:30 PM EDT
Stem Cell Models, Estimating Risk without Animals, and More Featured in September 2018 Toxicological Sciences
Society of Toxicology

Papers on stem cell methods and models in toxicology; comparative toxicogenomics and AOPs; machine vs. animal models; pesticides and asthma; and estimating risk without animals featured in latest issue of Toxicological Sciences.

Released: 3-Aug-2018 9:00 AM EDT
Nephrotoxicity, Nanomaterial Genotoxicity, Arsenic in Children, and More Featured in August 2018 Toxicological Sciences
Society of Toxicology

Papers on nephrotoxicity, nanomaterial genotoxicity, machine learning; arsenic and telomere length in children; iPSC-derived cardiomyoctes for drug safety studies; and asthma, air pollution, and immunity featured in latest issue of Toxicological Sciences

Released: 9-Jul-2018 5:45 PM EDT
Air Pollution, Green Plasticizers' Effect on Reproductive Health, and More Featured in July 2018 Toxicological Sciences
Society of Toxicology

Air pollution; thorax toxicology; PBPK modeling of antibiotics in dairy cattle; PCBs & steatohepatitis; uranium mine particles & cardiopulmonary toxicity; green plasticizers & reproductive health; and antiandrogenic mixtures & male reproduction featured in latest issue of Toxicological Sciences

Released: 5-Jun-2018 10:00 AM EDT
Antimicrobials and Colon Effects, Copper and Alzheimer’s Disease, and More Featured in June 2018 Toxicological Sciences
Society of Toxicology

Copper exposure’s link Alzheimer’s disease, the effects of consumer microbials on the colon, a potential prostate-based activation of a carcinogen in cooked meat, and the impact of hydraulic fracturing mixtures on the immune system featured in latest issue of Toxicological Sciences.

Released: 8-May-2018 5:30 PM EDT
Zebrafish for Toxicology Testing, Dietary Intervention for Pulmonary Injury & In Vitro Screening Featured in ToxSci
Society of Toxicology

New Toxicological Sciences features a historical perspective and contemporary review of zebrafish as a model in toxicology. There also are highlighted papers on dietary intervention for pulmonary injury; PBPK modeling for PFOA risk; IVIVE and toxicokinetics; and microelectrode arrays and seizures.

Released: 9-Apr-2018 4:00 PM EDT
In Vitro Chemical Screens; Ovary Effects of Personal Care Product Chemicals & More in April 2018 Toxicological Sciences
Society of Toxicology

Articles on personal care product chemicals; PBPK modeling; 2D vs 3D for drug-induced liver injury; zebrafish and drug discovery; glutathione restoration and acetaminophen; high-throughput screening for thyroid hormone T4; and genetically engineered food crops featured in new Toxicological Sciences.

Released: 8-Mar-2018 5:30 PM EST
Articles on Mitochondrial Toxicity, Metabolic Syndrome, AOPs, and More Featured in March 2018 Toxicological Sciences
Society of Toxicology

The Toxicological Sciences 20th anniversary celebration continues with articles on mitochondrial toxicity and organophosphorus compounds, in addition to featured papers on metabolic syndrome; paternal exposures and offspring’s mitochondria; data fusion and AOPs; DNA damage assay predictability; and imaging mammary epithelial organoids.

Newswise: Toxicological Concerns in Older Adults, a Neglected Majority
Released: 1-Mar-2018 5:15 PM EST
Toxicological Concerns in Older Adults, a Neglected Majority
Society of Toxicology

Despite a worldwide increase in individuals aged 60 or older, few issues in toxicological science associated with the aging process have been addressed, and the elderly remain a largely understudied, vulnerable population. SOT hosting meeting to discuss research and issues related to this topic.

Released: 19-Feb-2018 2:05 PM EST
Latest Research on Lead Exposure, Alternative Test Methods, Endocrine-Disrupting Chemicals, Nanoparticles, Perfluorinated Alkyl Substances (PFAS), and More Featured at SOT 57th Annual Meeting and ToxExpo
Society of Toxicology

With more than 6,500 individuals from around the world in attendance, the Society of Toxicology (SOT) 57th Annual Meeting and ToxExpo will feature leading experts from across the broad range of disciplines and specialties that inform and advance toxicology.

Released: 9-Jan-2018 5:05 PM EST
Toxicological Sciences Celebrates 20 Years
Society of Toxicology

January 2018 issue of SOT journal honors the publication's 20-year history and features the newest, groundbreaking research in toxicology.

Released: 14-Dec-2017 9:00 AM EST
Scientists at the Forefront of Understanding Exposure Risks and Leading Innovations in Toxicology Research Recognized with 2018 SOT Awards
Society of Toxicology

Through its awards, SOT honors more than two dozen groundbreaking scientists, emerging leaders, postdoctoral researchers, and graduate students who are advancing the science of toxicology. The SOT Awards also recognize the contributions of educators and science communicators as they work to encourage students to pursue STEM careers and improve public understanding of the connection between scientific research and public health.

Released: 7-Dec-2017 12:00 PM EST
SOT Releases Issue Statement on Low-Level Arsenic Exposure
Society of Toxicology

The Society of Toxicology (SOT) has approved a new Issue Statement on the issues and complexities associated with understanding the health risk from low-level arsenic exposure.

Released: 4-Dec-2017 9:00 AM EST
SOT Releases Issue Statement on Safety of Genetically Engineered Food Crops
Society of Toxicology

The Society of Toxicology (SOT) has approved a new Issue Statement on food and feed safety related to genetically engineered (GE) crops (commonly referred to as GMOs). The Society's journal, Toxicological Sciences, also has published a new forum article that provides an in-depth review of 20+ years of GE research.

Released: 9-Nov-2017 2:05 PM EST
Research Articles on Transcriptomics to Aid Risk Assessment, Pregnancy and Carcinogen Metabolism, and More Featured in Toxicological Sciences
Society of Toxicology

Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.

Released: 25-Oct-2017 3:05 PM EDT
October 2017 ToxSci Online: Impact of Gene-Editing Tools on Safety Assessment
Society of Toxicology

The October 2017 issue of Toxicological Sciences (Vol. 159, Issue 2) includes a wide range of articles on topics representing the latest in toxicological research and advances.

Released: 24-Aug-2017 10:00 AM EDT
Predatory Journals: How to Spot and Avoid Them
Society of Toxicology

Scientific research and publishing over the past decade has experienced some substantial transformations—and not in a good way. With an increasing number of poor-quality scientific journals appearing in the marketplace, it is important to know how to recognize potential scams.

Newswise: Opioid Abuse and Overdose: How Toxicologists Are Addressing This Public Health Crisis
Released: 24-May-2017 1:00 PM EDT
Opioid Abuse and Overdose: How Toxicologists Are Addressing This Public Health Crisis
Society of Toxicology

With increasing reports of and concerns about opioid abuse, there are actions toxicologists can take to help prevent and treat the problem.

Released: 6-Mar-2017 12:00 PM EST
Metabolic Syndrome: Toxicology’s Next Patient
Society of Toxicology

A rise in caloric consumption combined with a decrease in physical activity has contributed to a boom of metabolic diseases, such as type 2 diabetes mellitus and cardiovascular diseases (e.g., heart failure and stroke).

Released: 27-Jan-2017 8:00 AM EST
Latest Research on Data Science, Precision Medicine, Epigenetics, Food Safety, Arsenic, Pesticides, Alternative Test Methods, and More Featured at SOT 56th Annual Meeting and ToxExpo
Society of Toxicology

The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.

Released: 14-Dec-2016 10:00 AM EST
Researchers Studying Neurodegenerative Diseases, Painkillers, Animal Testing Alternatives, and More Recognized with 2017 SOT Awards
Society of Toxicology

The 2017 SOT Awards recipients have studied the role of pesticide exposure on neurodegenerative diseases, connections between chemicals and the susceptibility to allergies and asthma, risk assessment, alternative test methods and strategies, and more, in their efforts to improve public, animal and environmental health.

Released: 5-Oct-2016 4:05 PM EDT
Toxicoepigenetics: The Emerging Field Many Are Exploring Without Knowing It
Society of Toxicology

Toxicologists who research health, exposure-related disease, and susceptibility are actually concurrently studying the consequences of epigenetic regulation, which is why an understanding of toxicoepigenetics is so important.

Released: 29-Sep-2016 8:00 AM EDT
A New Way to Define Proarrhythmic Risk? Exploring Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes
Society of Toxicology

There generally are two approaches used to indirectly assess proarrhythmic risk, but some researchers believe that human induced pluripotent stem-cell derived (hiPSC)-cardiomyocytes offer an opportunity to change the paradigm.


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