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Newswise: Study focuses on repair and reversal of damage caused by Huntington’s disease
  • Embargo expired:
    16-Oct-2019 2:00 PM EDT

Article ID: 720785

Study focuses on repair and reversal of damage caused by Huntington’s disease

University of California, Los Angeles (UCLA), Health Sciences

A new study examining the role that star-shaped brain cells called astrocytes play in Huntington’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.

Released:
15-Oct-2019 1:00 PM EDT
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Newswise: UCLA opens pioneering CAR T clinical trial aimed at extending the lives of people diagnosed with the most common types of lymphoma and leukemia

Article ID: 720858

UCLA opens pioneering CAR T clinical trial aimed at extending the lives of people diagnosed with the most common types of lymphoma and leukemia

University of California, Los Angeles (UCLA), Health Sciences

This month, the UCLA Jonsson Cancer Center has launched a pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial that will attack cancer cells by simultaneously recognizing two targets – CD19 and CD20 – that are expressed on B-cell lymphoma and leukemia.

Released:
16-Oct-2019 11:05 AM EDT
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Newswise: Antibody eradicates leukemia stem cells

Article ID: 720782

Antibody eradicates leukemia stem cells

UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research

Now, in experiments in mice as well as isolated human cancer cells, UCLA researchers have discovered a way to eliminate the CML stem cells. Their approach uses an antibody to block a protein that the stem cells rely on to grow. The advance, described in a study published in the Journal of Clinical Investigation, might eventually help treat not only chronic myelogenous leukemia but other cancers as well.

Released:
15-Oct-2019 12:05 PM EDT
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  • Embargo expired:
    11-Oct-2019 11:00 AM EDT

Article ID: 720348

Expert second opinion improves reliability of melanoma diagnoses

University of California, Los Angeles (UCLA), Health Sciences

A new study led by UCLA researchers, have found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma, one of the deadliest and most aggressive forms of skin cancer.

Released:
8-Oct-2019 1:05 PM EDT
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Newswise: Clues from DNA could help predict growth of prostate cancer

Article ID: 720324

Clues from DNA could help predict growth of prostate cancer

University of California, Los Angeles (UCLA), Health Sciences

Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men’s genomes — the complete set of genetic material inherited from one’s parents — that predict how an individual person’s prostate cancer will grow. The finding suggests that predicting how a person’s cancer will evolve may lie in their inherited DNA.

Released:
7-Oct-2019 2:05 PM EDT
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Newswise: Researchers identify molecular process that could accelerate recovery from nerve injuries

Article ID: 720005

Researchers identify molecular process that could accelerate recovery from nerve injuries

UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered a molecular process that controls the rate at which nerves grow both during embryonic development and recovery from injury throughout life.

Released:
2-Oct-2019 11:05 AM EDT
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All Journal News, Neuro, Pain,

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  • Embargo expired:
    29-Sep-2019 10:30 AM EDT

Article ID: 719796

Adding Targeted Therapy Drug to Hormone Therapy Helps Women with Aggressive Breast Cancer Live Longer

University of California, Los Angeles (UCLA), Health Sciences

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

Released:
29-Sep-2019 4:05 AM EDT
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Article ID: 719721

UCLA to Lead $25 Million Opioid Study in Rural America

University of California, Los Angeles (UCLA), Health Sciences

Scientists from the UCLA Integrated Substance Abuse Programs will lead a $25 million National Institutes of Health study testing treatments, including the use of telemedicine, to help fight the opioid epidemic in rural America.

Released:
26-Sep-2019 6:05 PM EDT
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Social and Behavioral Sciences

Newswise: Researchers apply fat cells to deliver drug to suppress tumor growth
  • Embargo expired:
    25-Sep-2019 11:00 AM EDT

Article ID: 719432

Researchers apply fat cells to deliver drug to suppress tumor growth

University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice.

Released:
23-Sep-2019 10:05 AM EDT
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Newswise: Engineered killer T cells could provide long-lasting immunity against cancer

Article ID: 719485

Engineered killer T cells could provide long-lasting immunity against cancer

University of California, Los Angeles (UCLA), Health Sciences

In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals.

Released:
23-Sep-2019 5:05 PM EDT
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