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Newswise: Researchers create accurate model of organ scarring using stem cells in a lab

Researchers create accurate model of organ scarring using stem cells in a lab

University of California, Los Angeles (UCLA), Health Sciences

A team led by Dr. Brigitte Gomperts at UCLA has developed a “scar in a dish” model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.

Channels: All Journal News, Cancer, Cell Biology, Stem Cells, Cell (journal),

Released:
10-Dec-2019 5:05 PM EST
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Newswise: UCLA study shows inhibition of gene helps overcome resistance to immunotherapy
  • Embargo expired:
    9-Dec-2019 11:00 AM EST

UCLA study shows inhibition of gene helps overcome resistance to immunotherapy

University of California, Los Angeles (UCLA), Health Sciences

A new study from scientists at UCLA helps explain why some people with advanced cancer may not respond to one of the leading immunotherapies, PD-1 blockade, and how a new combination approach may help overcome resistance to the immunotherapy drug.

Channels: All Journal News, Cancer, Healthcare, Immunology, Pharmaceuticals, Nature (journal),

Released:
5-Dec-2019 12:25 PM EST
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Newswise: Taming chronic inflammation may reduce illness, save lives
  • Embargo expired:
    5-Dec-2019 11:00 AM EST
Released:
5-Dec-2019 5:00 AM EST
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Newswise: Automated technique helps identify cancer cell metabolism inhibitors
  • Embargo expired:
    29-Nov-2019 6:00 AM EST

Automated technique helps identify cancer cell metabolism inhibitors

University of California, Los Angeles (UCLA), Health Sciences

UCLA Jonsson Comprehensive Cancer Center researchers have developed a new automated method for testing hundreds of molecules at a time to find out which ones block cancer cells from consuming glucose — the sugars they need to spread and grow.

Channels: All Journal News, Cancer, National Institutes of Health (NIH),

Released:
28-Nov-2019 6:05 AM EST
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Newswise: Researchers identify protein that governs human blood stem cell self-renewal

Researchers identify protein that governs human blood stem cell self-renewal

University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions

Channels: All Journal News, Blood, Cancer, Cell Biology, Stem Cells, Nature (journal),

Released:
27-Nov-2019 2:25 PM EST
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Newswise: New screening method identifies inhibitors of cancer cell metabolism

New screening method identifies inhibitors of cancer cell metabolism

University of California, Los Angeles (UCLA), Health Sciences

A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell – nucleotide metabolism – to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.

Channels: All Journal News, Cancer, Cell Biology, Healthcare, Pharmaceuticals, Cell (journal),

Released:
18-Nov-2019 4:30 PM EST
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Newswise: Lung Cancer in Women - UCLA Health Pulmonologist describes the signs & symptoms of this deadly disease

Lung Cancer in Women - UCLA Health Pulmonologist describes the signs & symptoms of this deadly disease

University of California, Los Angeles (UCLA), Health Sciences

It's Lung Cancer Awareness Month and there are few stories about women who are diagnosed with lung cancer. Here’s one story about a 42-year-old, non-smoking Mom of two who was surprised with a lung cancer diagnosis last Thanksgiving. The story also features tips from a UCLA pulmonologist on the signs and symptoms of lung cancer.

Channels: All Journal News, Cancer, Healthcare, Men's Health, Women's Health,

Released:
15-Nov-2019 1:50 PM EST
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