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Newswise: Inhibiting Enzyme Helps Cancer Immunotherapy Work Better
Released: 3-Aug-2020 3:25 PM EDT
Inhibiting Enzyme Helps Cancer Immunotherapy Work Better
University of California San Diego Health

UC San Diego researchers discovered that people with an inactive RNA-editing enzyme respond better to cancer immunotherapy, and inhibitors of the enzyme help mice with difficult-to-treat cancers live longer.

Newswise: Precision Medicine Identifies Key Recurring Mutation in Head and Neck Cancers
Released: 30-Jul-2020 4:55 PM EDT
Precision Medicine Identifies Key Recurring Mutation in Head and Neck Cancers
University of California San Diego Health

Researchers at UC San Diego School of Medicine and Moores Cancer Center report that an investigational drug candidate called tipifarnib showed promise in treating key recurring mutation in head and neck cancers.

Newswise: Zafiris J. Daskalakis, MD, PhD, Named Chair of the Department of Psychiatry
Released: 30-Jul-2020 1:25 PM EDT
Zafiris J. Daskalakis, MD, PhD, Named Chair of the Department of Psychiatry
University of California San Diego Health

Zafiris J. “Jeff” Daskalakis, MD, PhD, has been named chair of the Department of Psychiatry at University of California San Diego School of Medicine.

Newswise: Botox Injections May Lessen Depression
28-Jul-2020 4:20 PM EDT
Botox Injections May Lessen Depression
University of California San Diego Health

By analyzing the FDA database of adverse drug effects, UC San Diego researchers discovered that people who received Botox injections — not just in the forehead — reported depression significantly less often than patients undergoing different treatments for the same conditions.

Newswise: UC San Diego Scientists Part of Special Package of Studies Describing Human Genome
Released: 29-Jul-2020 12:20 PM EDT
UC San Diego Scientists Part of Special Package of Studies Describing Human Genome
University of California San Diego Health

Researchers at UC San Diego School of Medicine are among the contributors to a package of 10 studies in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements project, a worldwide effort led by the NIH to understand how the human genome functions.

Newswise: UC San Diego Health Ranked #1 by U.S. News & World Report
Released: 28-Jul-2020 12:05 AM EDT
UC San Diego Health Ranked #1 by U.S. News & World Report
University of California San Diego Health

UC San Diego Health is ranked first in San Diego and sixth in California, placing it among the nation’s best hospitals, according to the 2020-2021 U.S. News & World Report. Eight common procedures and conditions were also rated “high performing.”

Newswise: A New Way to Target Cancers Using 'Synthetic Lethality'
27-Jul-2020 1:40 PM EDT
A New Way to Target Cancers Using 'Synthetic Lethality'
University of California San Diego Health

Researchers at Ludwig Institute for Cancer Research and University of California San Diego School of Medicine report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.

Newswise: National Clinical Trial Launches, Will Test Promising Vaccine Against Novel Coronavirus
Released: 24-Jul-2020 11:20 AM EDT
National Clinical Trial Launches, Will Test Promising Vaccine Against Novel Coronavirus
University of California San Diego Health

UC San Diego Health and the Altman Clinical and Translational Research Institute will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the coronavirus that causes COVID-19.

Newswise: Cancer Clinical Trials Tested, Continue During COVID-19 Pandemic
Released: 23-Jul-2020 2:05 PM EDT
Cancer Clinical Trials Tested, Continue During COVID-19 Pandemic
University of California San Diego Health

During the COVID-19 pandemic, Moores Cancer Center at UC San Diego Health continues to offer potentially lifesaving treatment through cancer clinical trials.

Newswise: Expanding Treatment Options for Severe Brain Trauma
Released: 23-Jul-2020 12:15 PM EDT
Expanding Treatment Options for Severe Brain Trauma
University of California San Diego Health

Researchers at UC San Diego Health have joined a national research study called Hyperbaric Oxygen Brain Injury Treatment (HOBIT) to assess whether therapy involving 100 percent oxygen under pressure might also benefit patients with severe brain injuries.

Newswise: So You Discovered Something that Might Save Lives … Now What?
Released: 16-Jul-2020 12:05 PM EDT
So You Discovered Something that Might Save Lives … Now What?
University of California San Diego Health

New UC San Diego Dissemination and Implementation Science Center provides researchers and practitioners with the training, technical assistance, mentoring and resources needed to implement their findings in real-world settings.

Newswise: Current Clinical Trial Assessing Potential of CBD in Treatment of Autism
Released: 14-Jul-2020 4:25 PM EDT
Current Clinical Trial Assessing Potential of CBD in Treatment of Autism
University of California San Diego Health

Researchers at University of California San Diego School of Medicine are recruiting eligible children between the ages of seven and fourteen years for a Phase III clinical trial to determine whether cannabidiol (CBD) reduces severe behavior problems in children with autism spectrum disorder.

Newswise: Human Sperm Stem Cells Grown in Lab, an Early Step Toward Infertility Treatment
9-Jul-2020 1:55 PM EDT
Human Sperm Stem Cells Grown in Lab, an Early Step Toward Infertility Treatment
University of California San Diego Health

By inhibiting the molecule AKT, UC San Diego researchers favor the culture of human spermatogonial stem cells in the lab, a first step toward lab-produced sperm as a treatment for male infertility.

Newswise: Does Blood Plasma from COVID-19 Survivors Help Patients Infected with Novel Coronavirus?
Released: 9-Jul-2020 4:05 PM EDT
Does Blood Plasma from COVID-19 Survivors Help Patients Infected with Novel Coronavirus?
University of California San Diego Health

Researchers at University of California San Diego School of Medicine and UC San Diego Health have launched a clinical trial to assess the safety and efficacy of convalescent plasma (CP) to prevent COVID-19 after a known exposure to the virus.

Newswise: How Old Is Your Dog in Human Years? Scientists Develop Better Method than ‘Multiply by 7’
29-Jun-2020 7:50 PM EDT
How Old Is Your Dog in Human Years? Scientists Develop Better Method than ‘Multiply by 7’
University of California San Diego Health

By mapping molecular changes in the genome over time, UC San Diego researchers developed a formula to more accurately compare dog age to human age — a tool that could also help them evaluate how well anti-aging products work.

Newswise: Universal Gut Microbiome-Derived Signature Predicts Cirrhosis
Released: 30-Jun-2020 1:05 PM EDT
Universal Gut Microbiome-Derived Signature Predicts Cirrhosis
University of California San Diego Health

UC San Diego School of Medicine researchers report that stool microbiomes of NAFLD patients are distinct enough to potentially be used to accurately predict which persons with NAFLD are at greatest risk for having cirrhosis.

Newswise: One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice
18-Jun-2020 4:25 PM EDT
One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice
University of California San Diego Health

UC San Diego researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.

Newswise: Immune Cells Infiltrating Tumors May Play Bigger Cancer Role Than Previously Thought
Released: 22-Jun-2020 3:15 PM EDT
Immune Cells Infiltrating Tumors May Play Bigger Cancer Role Than Previously Thought
University of California San Diego Health

UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells’ response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making IRE1α an attractive target for drug development.

Newswise: Novel Antisense Drug Shows Promise in Slowing Fatty Liver Disease
Released: 16-Jun-2020 1:20 PM EDT
Novel Antisense Drug Shows Promise in Slowing Fatty Liver Disease
University of California San Diego Health

A first-in-class clinical trial suggests a novel treatment measurably slowed progression of non-alcoholic fatty liver disease to its more progressive and deadly form.

Released: 15-Jun-2020 2:30 PM EDT
Longitudinal Study of Brain Aging and Cognitive Change Receives $19 Million Grant
University of California San Diego Health

Researchers at UC San Diego School of Medicine, with colleagues elsewhere, will receive almost $19 million over five years for the fourth phase of the Vietnam Era Twin Study of Aging, which investigates cognition, aging and the risk for mild cognitive impairment and Alzheimer’s disease.

Newswise: Putting “Super” in Natural Killer Cells
Released: 11-Jun-2020 1:20 PM EDT
Putting “Super” in Natural Killer Cells
University of California San Diego Health

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells — a type of immune cell — with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

Newswise: Mobile Life Support Delivered to Area Hospitals During COVID-19 Pandemic
Released: 26-May-2020 12:10 PM EDT
Mobile Life Support Delivered to Area Hospitals During COVID-19 Pandemic
University of California San Diego Health

UC San Diego Health has deployed a mobile ECMO life support system to help sustain critically-ill patients during the pandemic.

Newswise:Video Embedded during-covid-19-telehealth-reconnects-patients-with-health-care-providers
VIDEO
Released: 21-May-2020 11:55 AM EDT
During COVID-19, Telehealth Reconnects Patients with Health Care Providers
University of California San Diego Health

During COVID-19, UC San Diego Health expanded telehealth to provide patients with safe and convenient access to appointments with their health care providers. Video visits expanded by more than 50-fold.

Newswise: RNA Molecules in Maternal Blood May Predict Pregnancies at Risk for Preeclampsia
Released: 19-May-2020 12:30 PM EDT
RNA Molecules in Maternal Blood May Predict Pregnancies at Risk for Preeclampsia
University of California San Diego Health

UC San Diego researchers have identified small molecules in the blood of asymptomatic pregnant women that may predict risk for preeclampsia, responsible for a significant proportion of maternal and neonatal deaths, low birth weight and is a primary cause of premature birth.

Newswise: NIH Begins Clinical Trial of Hydroxychloroquine and Azithromycin to Treat COVID-19
Released: 15-May-2020 12:05 PM EDT
NIH Begins Clinical Trial of Hydroxychloroquine and Azithromycin to Treat COVID-19
University of California San Diego Health

The NIH has launched a major clinical trial to assess the malaria drug hydroxychloroquine and antibiotic azithromycin as a treatment for COVID-19. The trial will recruit 2,000 participants at 30 sites. A Q&A with the trial’s team leader: Davey Smith, MD, of UC San Diego School of Medicine.

Newswise: Ruth S. Waterman, MD, Named Chair of the Department of Anesthesiology
Released: 7-May-2020 4:30 PM EDT
Ruth S. Waterman, MD, Named Chair of the Department of Anesthesiology
University of California San Diego Health

Ruth S. Waterman, MD, has been named chair of the Department of Anesthesiology at University of California San Diego School of Medicine and UC San Diego Health.

Newswise: Introducing the UC San Diego Return to Learn Program
Released: 5-May-2020 4:05 PM EDT
Introducing the UC San Diego Return to Learn Program
University of California San Diego Health

Program makes COVID-19 testing available to thousands of students in effort to track the novel coronavirus and better position the campus to resume in-person activities in the fall.

Newswise: How Are You Doing? Researchers Hope to Measure Well-Being at Global Scale
Released: 5-May-2020 12:55 PM EDT
How Are You Doing? Researchers Hope to Measure Well-Being at Global Scale
University of California San Diego Health

With website, UC San Diego School of Medicine scientists will monitor health and well-being during and after pandemic.

Newswise: $55M NIH Grant Advances Clinical and Translational Research at UC San Diego
Released: 4-May-2020 1:40 PM EDT
$55M NIH Grant Advances Clinical and Translational Research at UC San Diego
University of California San Diego Health

The Altman Clinical and Translational Research Institute at University of California San Diego has received a five-year, $54.7 million Clinical and Translational Science Award from the National Center for Advancing Translational Science (NCATS), part of the National Institutes of Health.

Newswise: UC San Diego Health Offers Virtual Appointments to Patients with COVID-19
Released: 4-May-2020 11:35 AM EDT
UC San Diego Health Offers Virtual Appointments to Patients with COVID-19
University of California San Diego Health

UC San Diego Health now offers a telemedicine clinic to help patients with COVID-19 recover at home.

Newswise: Clinical Trial to Investigate Whether Hypertension Drug Ameliorates COVID-19 Severity
Released: 30-Apr-2020 4:40 PM EDT
Clinical Trial to Investigate Whether Hypertension Drug Ameliorates COVID-19 Severity
University of California San Diego Health

UC San Diego scientists have launched a clinical trial to investigate whether a drug approved for treating high blood pressure might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.

Newswise: UC San Diego Health Nationally Recognized with ‘A’ Grades for Safety
Released: 30-Apr-2020 1:05 PM EDT
UC San Diego Health Nationally Recognized with ‘A’ Grades for Safety
University of California San Diego Health

UC San Diego Health has been awarded double ‘A’ grades for the spring 2020 Leapfrog Hospital Safety Grade.

Newswise: Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia
Released: 29-Apr-2020 2:45 PM EDT
Arthritis Drug Presents Promise as Treatment for COVID-19 Pneumonia
University of California San Diego Health

UC San Diego Health has launched a Phase III clinical trial to assess whether a medication used to treat rheumatoid might also have therapeutic value for patient with COVID-19 who have developed or are at high risk of developing serious lung damage from SARS-CoV-2 infections.

Newswise: Loss of Smell Associated with Milder Clinical Course in COVID-19
Released: 27-Apr-2020 3:30 PM EDT
Loss of Smell Associated with Milder Clinical Course in COVID-19
University of California San Diego Health

Researchers at UC San Diego Health report in newly published findings that olfactory impairment suggests the resulting COVID-19 disease is more likely to be mild to moderate, a potential early indicator that could help health care providers determine which patients may require hospitalization.

Newswise: For ME/CFS Patients, Viral Immunities Come at a Devastating, Lifelong Cost
Released: 27-Apr-2020 2:10 PM EDT
For ME/CFS Patients, Viral Immunities Come at a Devastating, Lifelong Cost
University of California San Diego Health

Researchers at UC San Diego School of Medicine and three German universities describe an underlying biological basis for myalgic encephalomyelitis/chronic fatigue syndrome, illustrating how efforts by the body to boost immune system protections can come at physiological cost elsewhere.

Newswise: Gut Microbes Influence How Rat Brains React to Opioids
21-Apr-2020 12:15 PM EDT
Gut Microbes Influence How Rat Brains React to Opioids
University of California San Diego Health

Antibiotic treatment — which depletes gut microbes — drastically changes the parts of a rat’s brain that are activated during opioid addiction and withdrawal.

Newswise: Finding Leukemia’s Weakness Using Genome-Wide CRISPR Technology
Released: 20-Apr-2020 12:05 PM EDT
Finding Leukemia’s Weakness Using Genome-Wide CRISPR Technology
University of California San Diego Health

Researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia.

Newswise: UC San Diego Health Launches Novel Coronavirus Blood Testing to Identify Past Exposure
Released: 17-Apr-2020 12:05 PM EDT
UC San Diego Health Launches Novel Coronavirus Blood Testing to Identify Past Exposure
University of California San Diego Health

Physicians and scientists at UC San Diego Health have launched a pair of serological tests that will look for novel coronavirus antibodies—evidence in persons tested that they have previously been infected by the viral cause of COVID-19, even if they never experienced tell-tale symptoms.

Newswise: When Damaged, the Adult Brain Repairs Itself by Going Back to the Beginning
Released: 15-Apr-2020 2:05 PM EDT
When Damaged, the Adult Brain Repairs Itself by Going Back to the Beginning
University of California San Diego Health

When adult brain cells are injured, they revert to an embryonic state, say researchers at UC San Diego School of Medicine. In their newly adopted immature state, the cells become capable of re-growing new connections that, under the right conditions, can help to restore lost function.

Released: 14-Apr-2020 1:10 PM EDT
In Wake of COVID-19 Pandemic, a Crashing Wave of Neuropsychiatric Problems?
University of California San Diego Health

Researchers suggest that in the aftermath of the novel coronavirus pandemic, a host of neuropsychiatric challenges may remain — or emerge — for those recovering from COVID-19 infections.

Newswise: Manoj Monga, MD, Named New Chair of the Department of Urology
Released: 14-Apr-2020 11:35 AM EDT
Manoj Monga, MD, Named New Chair of the Department of Urology
University of California San Diego Health

Manoj Monga, MD, recognized as an international authority in endourology and stone disease, has been named chair of the Department of Urology at University of California San Diego School of Medicine and will see patients at UC San Diego Health.

Newswise: Loss of Smell and Taste Validated as COVID-19 Symptoms
Released: 13-Apr-2020 12:50 PM EDT
Loss of Smell and Taste Validated as COVID-19 Symptoms
University of California San Diego Health

Researchers at UC San Diego Health publish the first empirical findings that strongly associate sensory loss and COVID-19, the respiratory disease caused by the novel coronavirus.

Newswise: UC San Diego to Advance Stem Cell Therapies in New Space Station Lab
Released: 8-Apr-2020 3:45 PM EDT
UC San Diego to Advance Stem Cell Therapies in New Space Station Lab
University of California San Diego Health

UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.

Newswise: Artificial Intelligence Enables Rapid COVID-19 Lung Imaging Analysis at UC San Diego Health
Released: 7-Apr-2020 1:20 PM EDT
Artificial Intelligence Enables Rapid COVID-19 Lung Imaging Analysis at UC San Diego Health
University of California San Diego Health

With support from Amazon Web Services, UC San Diego Health physicians are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.

Newswise: Tested and Testing: UC San Diego Health Expands COVID-19 Diagnostics
Released: 6-Apr-2020 12:25 PM EDT
Tested and Testing: UC San Diego Health Expands COVID-19 Diagnostics
University of California San Diego Health

UC San Diego Health makes measurable progress addressing COVID-19 testing shortage through multiple partnerships and rapidly growing in-house testing. Success has meant more testing for more patients, first responders and other health systems.


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