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New research from the University of Cincinnati (UC) reveals that residents of the Mid-Ohio River Valley had higher than normal levels of perfluorooctanoic acid (PFOA) based on blood samples collected over a 22-year span. The exposure source was likely from drinking water contaminated by industrial discharges upriver. This is the first study of PFOA serum concentrations in U.S. residents in the 1990s.

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Researchers at the University of Cincinnati (UC) have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

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A recent review article in the European journal Seizure, by researchers at University of Cincinnati Epilepsy Center at the UC Gardner Neuroscience Institute, looks at the stress-seizure relationship and how adopting stress reduction techniques may provide benefit as a low risk form of treatment.

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Researchers at the University of Cincinnati (UC) College of Medicine have discovered a new potential strategy to personalize therapy for brain and blood cancers.

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A University of Cincinnati study reported that patients who sustained a concussion, followed by symptoms of visual dysfunction, experienced delayed central and peripheral vision reaction times.

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In a photo analysis study of soccer headers, University of Cincinnati researchers noticed female soccer players had their eyes closed 90 percent of the time. As a first step toward determining if less visual awareness might expose players to a higher risk of injury, the study wanted to quantify whether female athletes closed their eyes more frequently than male counterparts.

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Cancer researchers at the University of Cincinnati (UC) have found an obesity-associated protein’s role in leukemia development and drug response which could lead to more effective therapies for the illness.

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Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.

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A new study from researchers at the University of Cincinnati (UC) College of Medicine, suggests that even college-level athletes may be vulnerable to the effects of head trauma, and that even several years after graduation, college football players continue to show evidence of neuropathic brain changes.

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Patients with diabetes and suffering from acute kidney injury (AKI), proteinuria and uncontrolled blood sugar experience a sharp reduction in the number of years they have healthy renal function before being forced onto dialysis, according to researchers at the University of Cincinnati (UC) College of Medicine.

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Researchers at the University of Cincinnati (UC) have discovered that an ion channel, active within T cells (white blood cells), could be targeted to reduce the growth of head and neck cancers.

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Sufferers of migraines, cluster headaches, tension headaches or other headache disorders are at greater risk of developing a thyroid condition called hypothyroidism, according to a study by University of Cincinnati College of Medicine researchers.

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A new University of Cincinnati study looks at how young women's beliefs about alcohol and sex affect condom usage during sexual encounters involving alcohol.

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Marilyn Cotter recently needed a stress test following a bout of chest tightness. Unable to withstand exercise because of foot problems, Cotter, a 68-year-old grandmother from Delhi Township, wasn’t a candidate for a normal stress test that uses a treadmill. Instead, her physicians at University of Cincinnati Medical Center used a space-age option: an anti-gravity treadmill.

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Researchers at the University of Cincinnati (UC) are studying how cognitive therapy that uses mindfulness techniques, such as meditation, quiet reflection and facilitator-led discussion, may serve as an adjunct to pharmacological treatments for youth with anxiety disorders.

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Early findings by researchers at the University of Cincinnati (UC) College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

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Researchers at the University of Cincinnati (UC) College of Medicine have found that putting liver cancer patients on a medication regimen prior to undergoing a certain treatment could lead to shorter hospital stays and less chance for readmission due to complications.

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Female atrial fibrillation patients are less likely than their male counterparts to receive blood thinning therapies to prevent stroke, say University of Cincinnati College of Medicine researchers.

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A study led by Achala Vagal, MD, associate professor at the University of Cincinnati (UC) College of Medicine and a UC Health radiologist, looked at a group of untreated acute stroke patients and found that there was no evidence of time dependence on damage outcomes for the penumbra (tissue that is at risk of progressing to dead tissue but is still salvageable if blood flow is returned) but rather an association with collateral flow—or rerouting of blood through clear vessels.

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A team led by Achala Vagal, MD, associate professor at University of Cincinnati College of Medicine researchers wanted to see whether differences in race, sex and/or age mattered when it came to neuroimaging use, and these findings, which showed a difference for young patients, men and African-Americans, will be presented at the American Society of Neuroradiology’s annual meeting May 25 in Washington, DC.

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A new $1.7 million National Institutes of Health grant will help University of Cincinnati (UC) researchers continue their investigation of the protein Human Antigen R (HuR) and its possible role in cardiovascular disease, with the ultimate goal of translating this research to improve human health.

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Physician-researchers in the College of Medicine at the University of Cincinnati have developed a computerized decision support tool that uses a combination of patient information and characteristics to assist physicians and patients with decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation.

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Cancer researchers at the University of Cincinnati (UC) have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.

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Patients who get blood quickly after severe injuries are less likely to die, according to researchers from the University of Cincinnati (UC) Department of Emergency Medicine. In this study, researchers tracked trauma patients taken from the scene of their injury by AirCare to the University of Cincinnati Medical Center (UCMC) who received at least one unit of blood within 24 hours of arriving at the hospital. “Air Care is the only helicopter in the area to carry blood (and plasma), so we had the research platform to study how early blood transfusions impact outcomes,” explained Dr. Powell. Most patients received their first blood transfusion from AirCare or within one hour of getting to UCMC. For these patients, each 10 minute delay in getting blood increased the chances of death.

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A new, multicenter National Institutes of Health study to determine whether an over the counter fatty acid supplement, called DHA (Docosahexaenoic acid, an omega-3 fatty acid), can assist with reducing early preterm births.

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The Black Death swept Europe in the 14th century eliminating up to half of the population but it left genetic clues that now may aid a University of Cincinnati (UC) researcher in treating HIV patients co-infected with hepatitis C using an anti-retroviral drug therapy. Kenneth Sherman, MD, PhD, Gould Professor of Medicine, says he will look at the blood samples of nearly 3,000 patients, primarily individuals with hemophilia, who were exposed to HIV during the early 1980s and late 1990s, to see if an inherited genetic variant that protects against HIV might also help prevent injury from Hepatitis C and other liver diseases.

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A new study led by Michael Privitera, MD, professor of the Department of Neurology and director of the Epilepsy Center at the University of Cincinnati Neuroscience Institute, tested two generic lamotrigine (prescription antiepileptic) products and found no detectable difference in clinical effects among patients in the trial. The findings were published this week in an advance online edition of The Lancet Neurology.

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New research from the University of Cincinnati (UC) College of Medicine suggests that prenatal exposure to flame retardants and perfluoroalkyl substances (PFASs) commonly found in the environment may have a lasting effect on a child’s cognitive and behavioral development, known as executive function.