Around 1 per cent of the population carry a gene which could mean they have hearts ‘primed to fail’.
New treatment leaves liver cancer cells in limbo
This time next week, on Tuesday 11 October at Bletchley Park, sees the launch of an initiative to celebrate women in maths and computing. As a new branch of the existing Suffrage Science scheme, it will encourage women into science, and to reach senior leadership roles.
A team at the MRC Clinical Sciences Centre (CSC), based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer’s Disease.
Most molecular biologists look at how to switch on and regulate single genes. Scientists at the MRC Clinical Sciences Centre (CSC) have gone further, and have explored how to reawaken an entire set of inactive genes, a chromosome, that is present in every female human cell.
Scientists have shown that people who exercise for even a few hours each week can enlarge their hearts. This is a normal and beneficial response to exercise, but until now has only been recognised in athletes. The researchers say that doctors should now consider an individual’s activity level before diagnosing common heart conditions.
Star role for ‘Wars2’ gene in heart disease risk
Two-in-one approach could help keep brain cancer in check
A unique awards ceremony to raise the number of women in senior leadership roles in science will take place today (Tuesday 8th March), International Women's Day.
The organs in our body may have a sexual identity of their own, new research suggests.
Scientists have shown that the chemical signal dopamine plays an unexpected role in social interactions. In mice, nerve cells in the brain that release dopamine became particularly active in animals kept on their own for a short time.
Research suggests we do not yet have the whole story about how fertilised eggs produce the many different types of cell that make up our adult bodies.
Scientists have found that women who suffer unexplained heart failure towards the end of pregnancy or shortly after giving birth share certain genetic changes.
Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.
Scientists have shown for the first time that an enzyme crucial to keeping our immune system healthy “surfs” along the strands of DNA inside our cells.
Babies born with heart problems have a number of genetic changes in common, even when there is no family history of heart disease, scientists have found.
A promising new drug for sepsis is on the horizon thanks to new funding from the British Heart Foundation, which could help take the laboratory discovery into the clinic.
Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.
Researchers exploring the complex structure in which our DNA is stored inside our body’s cells have demonstrated that this structure depends crucially on a protein called ‘Hira’.
Researchers have shown that people with high blood pressure develop changes in their hearts even before symptoms appear.
A study, published today in the American Journal of Psychiatry, is the first to find that immune cells are more active in the brains of people at risk of schizophrenia* as well as those already diagnosed with the disease.
When our cells copy their DNA to grow and replicate, it’s vital the process runs smoothly. To get this right, cells use a complex “machine”, made from many hundreds of components.
The wriggling and writhing of worms may hold clues to the inner workings of our brains, according to scientists at the MRC’s Clinical Sciences Centre at Imperial College London. The researchers have developed a pioneering tool to analyse a worm’s posture as it wriggles, and will use the tool to investigate how exactly the worm’s brain controls its movements.
For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it’s a cellular pathway that’s found in everything from yeast to mammals.
Scientists have shown that women may not need to “eat for two” during pregnancy because the body adapts to absorb more energy from the same amount of food. The findings may also help to explain why some women struggle to lose weight after giving birth.
Research published in the journal Cell Reports challenges the most popular theory about why our bodies deteriorate in old age. Scientists know that as we grow older our cells accumulate particles, called free radicals. It has long been thought that free radicals wreak havoc by damaging proteins and impairing their function – but the new research shows that proteins can survive unscathed.
A gene called Jarid2, may play a wider role than previously thought in co-ordinating the way that stem cells change in a developing embryo to form the specialised cells that make up our bodies.
Scientists at the MRC’s Clinical Sciences Centre (CSC) in West London are the first to show that a small molecule circulates in the blood of people who are in the early stages of type 1 diabetes. A simple blood test could detect this biological marker years, maybe decades, before symptoms develop.
In a study published today in Genes & Development, Dr Christian Speck from the MRC Clinical Sciences Centre’s DNA Replication group, in collaboration with Brookhaven National Laboratory (BNL), New York, reveal the intricate mechanisms involved in the enzyme that governs DNA duplication during cell division.
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