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Released: 30-Nov-2017 2:05 AM EST
GBSI to Present at ASCB|EMBO 2017 in Philadelphia December 4 and 5
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) will introduce a new cell authentication training modules and videos to be available online for use by students, post-doctoral scholars, research faculty, educators and education administrators. The materials are part of a new GBSI program, “Enhancing Data Reproducibility Through Cell Authentication Training,” that will teach researchers to test for and decrease the likelihood of cell line contamination and misidentification, improving research reproducibility and decrease translation time from bench to clinic to bedside. The new step in education and training will ensuring more effective use of millions of dollars in research expenditures.

     
Released: 13-Nov-2017 8:00 AM EST
NIH Awards $2.34 Million to GBSI for Reverse Experimental Design Training to Improve Research Reproducibility
Global Biological Standards Institute (GBSI)

The National Institutes of Health (NIH) has awarded the Global Biological Standards Institute (GBSI) $2.34 million over five years for a groundbreaking experimental design training project to improve reproducibility in preclinical research. The project, entitled “Producing Reproducible Experiments by Promoting Reverse Experimental Design” (PREPaRED),* is a collaborative educational partnership between GBSI and faculty at Harvard Medical School, Vanderbilt University, Purdue University and Massachusetts Institute of Technology (MIT).

     
Released: 23-Oct-2017 9:10 AM EDT
Novel Antibody Scoring System Enters Alpha Testing
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) announced today that alpha testing has begun on a novel scorecard system to evaluate and rank research antibody performance. This first-of-its-kind antibody scorecard is a quantitative performance measuring system that will provide users detailed information as it pertains to a given antibody. The data would allow researchers to select antibodies for a given application based on their intrinsic on-target, off-target and other technical characteristics, ultimately improving accuracy and resulting in more reproducible research.

6-Oct-2017 4:55 PM EDT
GBSI BioPolicy Summit 2017 Explores the Laboratory of the Future and Technology’s Promising Impact on Reproducible Research
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) today brought top scientists and biomedical researchers together with science inventors and programmers to consider the laboratory of the future and explore how newly affordable and accessible digital tools, technologies and lab automation advances will increase reproducibility in preclinical research… and ultimately to accelerate the discovery of treatments and cures. GBSI’s 3rd BioPolicy Summit: “Improving Reproducibility of Research Through Digital Tools, Technologies and Laboratory Automation,” marked the first time the science tech community had brought their expertise to the reproducibility case.

     
Released: 4-Oct-2017 4:55 PM EDT
GBSI BioPolicy Summit 2017 Explores Newest Lab Automation, Digital Tools and Technologies Promising Improved Preclinical Research Reproducibility - October 16, in San Francisco
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute’s 3rd annual BioPolicy Summit: “Improving Reproducibility of Research Through Digital Tools, Technologies and Laboratory Automation,” will bring a diverse and interdisciplinary group of participants together—biologists, tech programmers, instrumentation manufacturers, the maker community, journals and funders—to explore how the newest life science research tools and technology can enhance reproducibility in preclinical research.

     
Released: 24-Jul-2017 5:00 PM EDT
The Global Biological Standards Institute’s 3rd Annual BioPolicy Summit: Improving Reproducibility of Research Through Digital Tools, Technologies and Laboratory Automation
Global Biological Standards Institute (GBSI)

The Global Biological Standards Institute’s 3rd annual BioPolicy Summit: Improving reproducibility of research through digital tools, technologies and laboratory automation is scheduled October 16, 2017, at the Mission Bay Conference Center in San Francisco.

16-Feb-2017 1:05 AM EST
GBSI Report Shows Encouraging Progress Towards Addressing Reproducibility to Significantly Improve Quality of Preclinical Biological Research by Year 2020
Global Biological Standards Institute (GBSI)

One year after the Global Biological Standards Institute (GBSI) issued its Reproducibility2020 challenge and action plan for the biomedical research community, the organization reports encouraging progress toward the goal to significantly improve the quality of preclinical biological research by year 2020. “Reproducibility2020 Report: Progress and Priorities,” posted today on bioRxiv, identifies action and impact that has been achieved by the life science research community and outlines priorities going forward. The report is the first comprehensive review of the steps being taken to improve reproducibility since the issue became more widely known in 2012.

   
16-Feb-2017 12:05 AM EST
Rigor and Reproducibility Policy One Year Later:How Has the Biomedical Community Responded?
Global Biological Standards Institute (GBSI)

Leonard P. Freedman, PhD, president of Global Biological Standards Institute (GBSI) will lead a panel discussion convened by GBSI, titled “Rigor and Reproducibility One Year Later: How Has the Biomedical Community Responded?” Freedman will also introduce a new GBSI report on the life science community’s multiple years of progress toward improved reproducibility by 2020. “Reproducibility2020 Report: Progress and Priorities,” also tracks the GBSI Reproducibility2020 challenge issued February 2016.

   
28-Sep-2016 4:05 AM EDT
Three Key Approaches to Increasing Research Antibody Validation Defined at GBSI Workshop
Global Biological Standards Institute (GBSI)

Leading experts from the international biomedical research community announced today that they have the fundamentals of what will become the first detailed standardized guidelines for validating research antibodies. The outcomes of this week’s Antibody Validation: Standards, Policies, and Practices workshop promise to increase reproducibility in preclinical research and improve the chances for breakthroughs in treatments and cures.

     
Released: 20-Sep-2016 1:05 AM EDT
GBSI’s Workshop Gathers 100+ Biomedical Research Experts at Asilomar toDevelop the First Practical, Implementable Antibody Validation Guidelines
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) gathers 100+ biomedical research experts from around the world next week at the scientifically historic Asilomar Conference Grounds in California for a workshop to discuss, define and vote on the first detailed standardized guidelines for validating research antibodies. Antibody Validation: Standards, Policies, and Practices will build upon the conceptual framework published September 5, in Nature Methods, in order to establish practical, applicable and implementable antibody validation guidelines. A webcast press briefing will present broad consensus-based outcomes September 28. Follow along on Twitter with #AbValidate.

     
Released: 25-Aug-2016 3:05 AM EDT
GBSI Antibody Validation Workshop Gathers Key Stakeholder Groups at Asilomar To Find Actionable Solutions for Improving Reproducibility in Research
Global Biological Standards Institute (GBSI)

The Global Biological Standards Institute (GBSI) targets the quality of research antibodies at a workshop at Asilomar next month in its ongoing efforts to improve reproducibility in preclinical research. Antibody Validation: Standards, Policies, and Practices brings together 100 leaders representing academia, antibody producers, pharma, funders, journals and policy makers to share perspectives, build consensus and recommend actionable solutions for improving accuracy in research antibody usage and validation. It is the first convening of all such stakeholder groups with the express purpose of developing antibody standards.

   
27-Jun-2016 12:05 AM EDT
GBSI Survey of Research Antibody Usage and Validation Practices Shows More Training of Younger Scientists and Efficient Methods of Validation Are Essential
Global Biological Standards Institute (GBSI)

A survey published today on research antibody usage and validation practices indicates many junior scientists are not receiving the training they need in the selection, handling, applications and reporting of research antibodies. "The need for improved education and training in research antibody usage and validation practices" by Leonard P. Freedman, PhD, published in BioTechniques, describes a perception among all researchers that antibody validation delays, rather than facilitates research progress.

Released: 17-Feb-2016 9:05 AM EST
70 Top Scientists and Industry Leaders Pinpoint Solutions to Improve Research Reproducibility at GBSI’s 2016 BioPolicy Summit
Global Biological Standards Institute (GBSI)

More than 70 leading scientists and industry leaders gathered last week in Washington, DC and via webcast to take on the problem of reproducibility in preclinical research that is a major concern in the biomedical community and continues to contribute to delays and increased costs of discoveries and development of treatments and cures. Global Biological Standard Institute (GBSI) hosted the discussion at its 2016 BioPolicy Summit—Research Reproducibility: Innovative Solutions to Drive Quality. The archived webcast is available now.

     
Released: 27-Jan-2016 12:05 AM EST
GBSI Doubles Down on Research Reproducibility at Annual BioPolicy Summit and Webcast in Washington, DC, February 9th
Global Biological Standards Institute (GBSI)

On Tuesday, February 9, at 12:00 noon EST, Global Biological Standards Institute (GBSI) will host its 2016 BioPolicy Summit at the Newseum in Washington, DC. The 2016 Summit—Research Reproducibility: Innovative Solutions to Drive Quality welcomes premiere life science thought leaders as speakers, panelists and guests who will review the complex causes of irreproducibility and focus on tangible solutions to drive greater research quality and accelerate the discovery of life-saving therapies.

Released: 17-Dec-2015 2:05 AM EST
Winning Video from GBSI #authenticate Campaign Will Promote Reproducibility Among Younger Generation of Biomedical Researchers
Global Biological Standards Institute (GBSI)

The Global Biological Standards Institute (GBSI) today announced the winner of its #authenticate video competition to promote cell authentication in biomedical research is Michael Ge, from West Covina, California. A Computer Science concentrator at Harvard University, Ge's 2.5-minute animated video amusingly illustrates the importance of cell authentication to research, suggesting a simple solution: the consistent use of an accurate and inexpensive test such as the short-tandem repeat (STR) analysis. The video will be a featured tool of the #authenticate campaign’s social media component that targets biomedical scientists, especially students and other trainees.

Released: 12-Oct-2015 3:00 PM EDT
GBSI’s Cell Authentication Survey Shows Little Progress in a Decade
Global Biological Standards Institute (GBSI)

A new survey of almost 450 biomedical researchers from every major stakeholder group (e.g., academia, industry) conducted by the Global Biological Standards Institute (GBSI) shows little has changed in cell line authentication and culture practices in the past decade—practices that contribute to irreproducible research, and delays and increased costs of drug discovery. The results are detailed in The culture of cell culture practices and authentication—Results from a 2015 Survey, by Leonard P. Freedman, Ph.D., lead author, published today in the open access journal BioTechniques.

Released: 4-Aug-2015 8:45 AM EDT
GBSI’s #Authenticate Campaign Tops 100 Supporters as Susan G. Komen® Champions Cause
Global Biological Standards Institute (GBSI)

Global Biological Standards Institute (GBSI) announced today that Susan G. Komen has signed on as Champion of its #authenticate campaign, bringing the total to more than 100 official supporters of the initiative. The campaign, launched in April 2015, seeks to expand cell line authentication in biomedical research in order to decrease the use of misidentified and contaminated cell lines and ultimately advance cures. GBSI is encouraging widespread adoption of cell authentication.

5-Jun-2015 8:05 AM EDT
New Study on Research Reproducibility Proposes Fixes for $28 Billion Problem
Global Biological Standards Institute (GBSI)

Approximately $28 billion per year is spent on preclinical research that is not reproducible AND the cumulative prevalence of irreproducible preclinical research exceeds 50 percent. The study, The Economics of Reproducibility in Preclinical Research, by Drs. Leonard P. Freedman, Iain M. Cockburn and Timothy S. Simcoe, outlines a framework for solutions and a plan for long-term improvements in life science research reproducibility rates.

   

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