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Newswise: Wistar Scientists Identify Pro-aging ‘Sugar Signature’ in the Blood of People Living with HIV
Released: 10-Apr-2024 9:30 AM EDT
Wistar Scientists Identify Pro-aging ‘Sugar Signature’ in the Blood of People Living with HIV
Wistar Institute

Wistar's Dr. Abdel-Mohsen has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.

Newswise: The Wistar Institute Appoints Max Berger to its Board of Trustees
Released: 27-Feb-2024 11:05 AM EST
The Wistar Institute Appoints Max Berger to its Board of Trustees
Wistar Institute

The Wistar Institute Appoints Max Berger to its Board of Trustees

Newswise: Wistar Scientists Discover Link Between Leaky Gut and 
Accelerated Biological Aging
Released: 23-Feb-2024 10:05 AM EST
Wistar Scientists Discover Link Between Leaky Gut and Accelerated Biological Aging
Wistar Institute

Wistar Institute’s Dr. Mohamed Abdel-Mohsen has demonstrated a connection between viral damage to the gut and premature biological aging.

Newswise: The Wistar Institute Announces New Caspar Wistar Fellow, Dr. Irene Bertolini
Released: 15-Feb-2024 4:05 PM EST
The Wistar Institute Announces New Caspar Wistar Fellow, Dr. Irene Bertolini
Wistar Institute

Wistar Institute is pleased to announce the recruitment of Irene Bertolini, Ph.D., to pursue research in breast and brain cancers.

Newswise: Wistar’s Jessie Villanueva, Ph.D., Receives ‘Diversity in Business’ Award
Released: 15-Feb-2024 3:05 PM EST
Wistar’s Jessie Villanueva, Ph.D., Receives ‘Diversity in Business’ Award
Wistar Institute

Jessie Villanueva, Ph.D., is one of the recipients of the 2024 Diversity in Business Award from the Philadelphia Business Journal.

Newswise: The Wistar Institute Recruits Dr. Filippo Veglia to the Ellen and Ronald Caplan Cancer Center
Released: 4-Jan-2024 10:05 AM EST
The Wistar Institute Recruits Dr. Filippo Veglia to the Ellen and Ronald Caplan Cancer Center
Wistar Institute

The Wistar Institute is pleased to announce the recruitment of Filippo Veglia, Ph.D., to the Ellen and Ronald Caplan Cancer Center, where he joins Wistar’s Immunology, Microenvironment and Metastasis Program as an Assistant Professor.

Newswise: The Wistar Institute Announces the Appointment of Aleister Saunders, Ph.D., and Patrick Oates, Ph.D., to its Board of Trustees
Released: 18-Dec-2023 10:05 AM EST
The Wistar Institute Announces the Appointment of Aleister Saunders, Ph.D., and Patrick Oates, Ph.D., to its Board of Trustees
Wistar Institute

The Wistar Institute is pleased to welcome Aleister Saunders, Ph.D., and Patrick Oates, Ph.D., to its Board of Trustees. The two new trustees bring a wealth of experience in biomedical research, technology transfer, and drug development to Wistar’s mission.

Newswise: Wistar Scientists Enhance Cell-Based Therapy to Destroy Solid Tumors
Released: 13-Dec-2023 11:35 AM EST
Wistar Scientists Enhance Cell-Based Therapy to Destroy Solid Tumors
Wistar Institute

Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells — an approach known as “cell-based therapy,” which uses specially designed T cells to fight cancer.

Newswise: Wistar President Dario Altieri, M.D., recognized as one of Philadelphia’s Most Admired CEOs
4-Dec-2023 10:05 AM EST
Wistar President Dario Altieri, M.D., recognized as one of Philadelphia’s Most Admired CEOs
Wistar Institute

Dario C. Altieri, M.D. — The Wistar Institute’s president and CEO, director of its Ellen and Ronald Caplan Cancer Center and the Robert & Penny Fox Distinguished Professor — is a recipient of the 2023 Most Admired CEO Awards recognized by the Philadelphia Business Journal for his leadership and service to Wistar.

Newswise: Dean Stoios Joins The Wistar Institute as Chief Financial Officer
Released: 17-Oct-2023 2:05 PM EDT
Dean Stoios Joins The Wistar Institute as Chief Financial Officer
Wistar Institute

The Wistar Institute announces the appointment of Dean Stoios as Chief Financial Officer. 

Newswise: Wistar President and CEO Dario Altieri, M.D., honored by Justinian Society of Philadelphia for Civic Engagement and Leadership
Released: 26-Sep-2023 1:05 PM EDT
Wistar President and CEO Dario Altieri, M.D., honored by Justinian Society of Philadelphia for Civic Engagement and Leadership
Wistar Institute

Dario C. Altieri, M.D., Wistar president and CEO, will be honored by the Justinian Foundation and Society of Philadelphia for exemplifying the finest qualities of scholarship, civic leadership and integrity.

Newswise: Wistar Researchers Discover Possible New Treatment for Triple-Negative Breast Cancer 
Released: 18-Sep-2023 12:05 PM EDT
Wistar Researchers Discover Possible New Treatment for Triple-Negative Breast Cancer 
Wistar Institute

Zachary Schug, Ph.D., assistant professor at The Wistar Institute, has published a new paper in the journal Nature Cancer demonstrating a double-acting mechanism for fighting a particularly aggressive, difficult-to-treat form of breast cancer.

Newswise: The Wistar Institute Recruits Dr. Avi Srivastava as Assistant Professor 
  
Released: 7-Sep-2023 2:05 PM EDT
The Wistar Institute Recruits Dr. Avi Srivastava as Assistant Professor   
Wistar Institute

Wistar is pleased to announce the recruitment of Avi Srivastava, Ph.D., to the Ellen and Ronald Caplan Cancer Center, where he joins Wistar’s Gene Expression and Regulation Program as an Assistant Professor.

Newswise: Wistar Researchers Discover Potential Target for Gastric Cancers Associated with Epstein-Barr Virus
Released: 22-Aug-2023 12:00 PM EDT
Wistar Researchers Discover Potential Target for Gastric Cancers Associated with Epstein-Barr Virus
Wistar Institute

Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.

Newswise: The Wistar Institute Recruits Virology Expert Alexander Price, Ph.D., to Cancer Center
9-Aug-2023 8:45 AM EDT
The Wistar Institute Recruits Virology Expert Alexander Price, Ph.D., to Cancer Center
Wistar Institute

The Wistar Institute is pleased to announce the appointment of Alexander Price, Ph.D., as assistant professor in the Gene Expression and Regulation Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute.

Newswise: The Wistar Institute Appoints Life Sciences Consultant and Entrepreneur Joy Taylor to its Board of Trustees
Released: 8-Aug-2023 11:10 AM EDT
The Wistar Institute Appoints Life Sciences Consultant and Entrepreneur Joy Taylor to its Board of Trustees
Wistar Institute

The Wistar Institute, a global leader in biomedical research in cancer, immunology and infectious disease, is pleased to welcome Joy Taylor to its Board of Trustees. Taylor is CEO of EastEdge Consulting Services, a Pennsylvania-based management consulting firm focused on organizational and operational improvement.

   
Newswise: New Community Partnership Model Boosts Inclusion of Participants into HIV Cure-Directed Research
Released: 19-Jul-2023 12:05 PM EDT
New Community Partnership Model Boosts Inclusion of Participants into HIV Cure-Directed Research
Wistar Institute

Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.

   
Newswise: Wistar Honors Pediatric HIV Researcher in 27th Annual Jonathan Lax Memorial Award Lecture
Released: 22-Jun-2023 10:00 AM EDT
Wistar Honors Pediatric HIV Researcher in 27th Annual Jonathan Lax Memorial Award Lecture
Wistar Institute

Wistar hosts its 27th Jonathan Lax Memorial Lecture Thursday, June 29th at 5:30 pm EST.

Released: 20-Jun-2023 10:05 AM EDT
Wistar Institute Study Gives New Insight into How Cancer Metastasizes to the Brain 
Wistar Institute

PHILADELPHIA — (June 20, 2023) — When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

Newswise: Former Philadelphia City Solicitor Sozi Tulante Appointed to Wistar Institute Board of Trustees
Released: 14-Jun-2023 10:05 AM EDT
Former Philadelphia City Solicitor Sozi Tulante Appointed to Wistar Institute Board of Trustees
Wistar Institute

Wistar is pleased to welcome Sozi Tulante to its Board of Trustees. He is currently General Counsel of Form Energy, a Massachusetts-based energy storage technology and manufacturing company.

Newswise: The Wistar Institute, Pennsylvania Biotechnology Center and Baruch S. Blumberg Institute Forge Strategic Collaboration to Support Regional Biotech Startups
Released: 9-May-2023 10:05 AM EDT
The Wistar Institute, Pennsylvania Biotechnology Center and Baruch S. Blumberg Institute Forge Strategic Collaboration to Support Regional Biotech Startups
Wistar Institute

Wistar Institute has formed a collaboration with the Pennsylvania Biotechnology Center and the Baruch S. Blumberg Institute to accelerate the advancement of “bench to bedside” biomedical research discoveries in the tri-state region.

Newswise: Wistar Scientists Discover Innate Tumor Suppression Mechanism
4-May-2023 9:20 AM EDT
Wistar Scientists Discover Innate Tumor Suppression Mechanism
Wistar Institute

Wistar Institute researchers have uncovered a key mechanism as to how p53 suppresses tumors.

   
Newswise: Researchers Identify a Plant-based Compound that Inhibits Reactivation of the HIV Viral Reservoir, Giving the Immune System a Break
Released: 28-Mar-2023 12:05 PM EDT
Researchers Identify a Plant-based Compound that Inhibits Reactivation of the HIV Viral Reservoir, Giving the Immune System a Break
Wistar Institute

Wistar Institute researchers identified hopeaphenol, a natural plant-based compound, as possessing antiviral properties that are effective against HIV.

   
Newswise: Wistar Scientists Identify a Gene Signature to Assess Cancer Risk in People
Released: 6-Feb-2023 3:45 PM EST
Wistar Scientists Identify a Gene Signature to Assess Cancer Risk in People
Wistar Institute

Wistar scientists have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

   
Released: 31-Jan-2023 10:05 AM EST
Wistar Institute Announces New Cotswold Foundation Postdoctoral Fellowship and Selected Fellow
Wistar Institute

The Cotswold Foundation Postdoctoral Fellowship is a new fellowship totaling $500,000 over the course of five years to support a postdoctoral researcher studying immunology, cancer research, or vaccine biology at The Wistar Institute.

Newswise: Michael Criscuolo joins The Wistar Institute as Vice President of Development
Released: 24-Jan-2023 1:45 PM EST
Michael Criscuolo joins The Wistar Institute as Vice President of Development
Wistar Institute

The Wistar Institute, which has recently launched a $75 million programmatic campaign investing in biomedical advances, announces the appointment of Michael Criscuolo as Vice President of Development.

Newswise: Wistar Institute HIV Researchers Win Grant to Explore Genetically Engineered Natural Killer Cells as HIV Therapy
Released: 19-Jan-2023 2:35 PM EST
Wistar Institute HIV Researchers Win Grant to Explore Genetically Engineered Natural Killer Cells as HIV Therapy
Wistar Institute

amfAR, The Foundation for AIDS Research, has awarded Luis J. Montaner, D.V.M., D.Phil., in collaboration with Mohamed Abdel-Mohsen, Ph.D., a Target Grant for $397,663 over two years.

Newswise: Wistar Institute’s Maureen Murphy Named Deputy Director of the Ellen and Ronald Caplan Cancer
Released: 12-Jan-2023 1:20 PM EST
Wistar Institute’s Maureen Murphy Named Deputy Director of the Ellen and Ronald Caplan Cancer
Wistar Institute

Maureen Murphy, Ph.D., has been named Deputy Director of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute. Murphy will guide the growth of the Cancer Center through expanding research initiatives and collaboration, education and training programs, and recruitment to fast-track innovative basic cancer research discoveries into future transformative drugs and therapies.

Newswise: BioBuzz Workforce Champion Award goes to Wistar’s New Biomedical Technician Training Program
Released: 14-Dec-2022 2:25 PM EST
BioBuzz Workforce Champion Award goes to Wistar’s New Biomedical Technician Training Program
Wistar Institute

The Wistar Institute Biomedical Technician Training (BTT) Program was awarded Workforce Champion of the Year in the 3rd Annual 2022 BioBuzz Awards. The program is a collaborative that includes The Wistar Institute, West Philadelphia Skills Initiative, Iovance Biotherapeutics, PIDC, and others.

   
Newswise: “The London Patient” Adam Castillejo Speaks at William Way Community Center to Spread Hope for a Future HIV  Cure
Released: 20-Oct-2022 2:05 PM EDT
“The London Patient” Adam Castillejo Speaks at William Way Community Center to Spread Hope for a Future HIV  Cure
Wistar Institute

The Wistar Insitute, William Way Community Center, Philadelphia FIGHT, BEAT-HIV Delaney Collaboratory, Philadelphia Foundation, and The Penn Center for AIDS Research are proud to announce that “The London Patient” Adam Castillejo will take part in a panel conversation and Q&A on Wednesday, October 26 from 5 to 8 pm

Newswise: Wistar Scientists Identify Link Between Mitochondria and Pancreatic Cancer Risk
12-Oct-2022 11:15 AM EDT
Wistar Scientists Identify Link Between Mitochondria and Pancreatic Cancer Risk
Wistar Institute

In a research paper published in PLOS ONE, The Wistar Institute's Dario C. Altieri, M.D., alongside national and international collaborators, distinguish a specific gene signature indicative of mitochondrial reprogramming in tumors that correlates with poor patient outcome.

Newswise: Wistar’s Dr. Amelia Escolano Earns NIH Director’s New Innovator Award
Released: 4-Oct-2022 10:00 AM EDT
Wistar’s Dr. Amelia Escolano Earns NIH Director’s New Innovator Award
Wistar Institute

The National Institutes of Health has awarded Amelia Escolano, Ph.D., assistant professor in The Wistar Institute’s Vaccine & Immunotherapy Center, the 2022 NIH Director’s New Innovator Award.

Newswise: Wistar Scientists Identify Key Biomarkers that Reliably Predict Response to Immune Checkpoint Inhibitor Therapy for Melanoma 
Released: 19-Sep-2022 9:00 AM EDT
Wistar Scientists Identify Key Biomarkers that Reliably Predict Response to Immune Checkpoint Inhibitor Therapy for Melanoma 
Wistar Institute

Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research out of The Wistar Institute now provides evidence of novel, reliable biomarkers that predict therapy response using advanced computer technology.

Newswise: The Wistar Institute Welcomes Michele A. Schiavoni, New Vice President of Communications &  Marketing
Released: 8-Sep-2022 12:55 PM EDT
The Wistar Institute Welcomes Michele A. Schiavoni, New Vice President of Communications &  Marketing
Wistar Institute

The Wistar Institute is pleased to announce the appointment of Michele A. Schiavoni, M.S., as Vice President of Communications & Marketing, in a central leadership role that will bolster the visibility of the Institute’s ambitious biomedical research science initiatives and programs advancing the organization’s newly launched Bold Science // Global Impact Capital Campaign.

   
Newswise: The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils Halts Cancer Progression and Metastasis
Released: 7-Sep-2022 11:05 AM EDT
The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils Halts Cancer Progression and Metastasis
Wistar Institute

Researchers in the laboratory of Yulia Nefedova, M.D., Ph.D., at The Wistar Institute and collaborators at Jubilant Therapeutics Inc. have uncovered a novel mechanism by which protein arginine deiminase 4 (PAD4) in neutrophils promotes cancer progression. The paper also found that inhibition of this function of PAD4 reduces primary tumor growth and metastasis and enhances checkpoint inhibitor treatments.

Newswise: Wistar Receives Merit Extension from the National Cancer Institute
Released: 2-Aug-2022 10:35 AM EDT
Wistar Receives Merit Extension from the National Cancer Institute
Wistar Institute

The National Cancer Institute (NCI) has granted a Merit Extension Award to The Wistar Institute’s Ellen and Ronald Caplan Cancer Center totaling more than $5 million.

Newswise: Wistar Scientists Reveal New Function of Enzyme ADAR1 Linking it to Age-Related Diseases via a Role Independent of RNA-editing During Aging
18-Jul-2022 8:05 AM EDT
Wistar Scientists Reveal New Function of Enzyme ADAR1 Linking it to Age-Related Diseases via a Role Independent of RNA-editing During Aging
Wistar Institute

Published today in Nature Cell Biology, Wistar scientists revealed a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence and its potential implications in tissue aging.

Newswise: The Wistar Institute Names Gelvina Rodriguez Stevenson, Esq., as Vice President, General Counsel, Secretary and Government Relations
Released: 13-Jul-2022 10:00 AM EDT
The Wistar Institute Names Gelvina Rodriguez Stevenson, Esq., as Vice President, General Counsel, Secretary and Government Relations
Wistar Institute

The Wistar Institute announces the appointment of Gelvina Rodriguez Stevenson, Esq., as vice president, general counsel, secretary and government relations.

Newswise: Collaboration Advances DNA-delivered Antibodies to Prevent COVID-19
7-Jul-2022 9:20 AM EDT
Collaboration Advances DNA-delivered Antibodies to Prevent COVID-19
Wistar Institute

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

Newswise: Jonathan Lax Memorial Award Lecture Streams Globally
Released: 24-Jun-2022 9:35 AM EDT
Jonathan Lax Memorial Award Lecture Streams Globally
Wistar Institute

Wistar announces that for the first time it will globally stream its 26th Annual Jonathan Lax Memorial Award Lecture, celebrating 26 years of providing state-of-research updates to the community, on Tuesday, June 28 from 9:30 to 11:00 a.m. EST.

Newswise: Wistar Scientists Identify Novel Therapeutic Approach to Re-Activate Immune Response Against Tumors
Released: 21-Jun-2022 10:00 AM EDT
Wistar Scientists Identify Novel Therapeutic Approach to Re-Activate Immune Response Against Tumors
Wistar Institute

Wistar scientists identified that inhibiting therapeutic target KDM5A boosts a person’s immune response to tumors.

   
Newswise: Wistar Institute Launches Bold Science // Global Impact Capital Campaign to Rechart the Future of Human Health
Released: 16-Jun-2022 10:05 AM EDT
Wistar Institute Launches Bold Science // Global Impact Capital Campaign to Rechart the Future of Human Health
Wistar Institute

Wistar Institute announces its Bold Science // Global Impact Capital Campaign to support a five-year plan that sets out Wistar’s roadmap for accelerated progress to drive breakthroughs in biomedical science and technology and educate and train the next generation of innovators.

   
Newswise: Wistar Scientists Move HIV Vaccine Research Forward by Developing an Immunogen that Produces Tier-2 Antibodies—the Kind That Matter for Combatting HIV
3-Feb-2022 3:55 PM EST
Wistar Scientists Move HIV Vaccine Research Forward by Developing an Immunogen that Produces Tier-2 Antibodies—the Kind That Matter for Combatting HIV
Wistar Institute

Wistar Institute scientists take a promising step in the direction of developing an HIV vaccine that uses a unique native-like trimer to develop Tier-2 neutralizing antibodies—the kind that matter for combatting HIV—in mice for the first time.

Newswise: Novel Nanoparticle SARS-CoV-2 Vaccine Combines Immune Focusing and Self-assembling Nanoparticles to Elicit More Potent Protection
Released: 1-Feb-2022 11:35 AM EST
Novel Nanoparticle SARS-CoV-2 Vaccine Combines Immune Focusing and Self-assembling Nanoparticles to Elicit More Potent Protection
Wistar Institute

The first generation of COVID-19 vaccines have been highly effective, but also have limitations. Now Wistar scientists have developed a more targeted vaccine that, in animal studies, shows stronger, broader, and more durable protection in a single, low dose.

   
Newswise: Wistar Scientists Identify Therapeutic Target for Epstein-Barr Virus
17-Jan-2022 5:00 AM EST
Wistar Scientists Identify Therapeutic Target for Epstein-Barr Virus
Wistar Institute

A new study by Wistar researchers has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

Newswise: The Wistar Institute and Stanford Medicine to Begin Phase 2 Clinical Trial of VK-2019 in Patients with Epstein-Barr Virus (EBV)-Positive Advanced Nasopharyngeal Carcinoma
Released: 5-Jan-2022 9:35 AM EST
The Wistar Institute and Stanford Medicine to Begin Phase 2 Clinical Trial of VK-2019 in Patients with Epstein-Barr Virus (EBV)-Positive Advanced Nasopharyngeal Carcinoma
Wistar Institute

Wistar announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

Newswise: Fox Chase Cancer Center, The Wistar Institute Announce Opening of Phase 1 Clinical Trial of Anticancer Drug Candidate
Released: 2-Dec-2021 11:20 AM EST
Fox Chase Cancer Center, The Wistar Institute Announce Opening of Phase 1 Clinical Trial of Anticancer Drug Candidate
Wistar Institute

Fox Chase Cancer Center has opened an investigator-initiated, phase 1 clinical trial to evaluate the safety and efficacy of gamitrinib in patients with advanced cancer.

29-Nov-2021 6:00 PM EST
Wistar Scientists Identify Genes Critical to Protecting Ovarian Cancer from the Immune System
Wistar Institute

Scientists at The Wistar Institute have identified two genes that play a critical role in protecting ovarian cancer from the immune system.

23-Nov-2021 8:50 AM EST
The Wistar Institute Receives $4 Million in Funding From the Commonwealth of Pennsylvania to Advance COVID-19 Research, Address COVID-19 Risk on Vulnerable Populations, and Assess Pandemic Preparedness
Wistar Institute

The Commonwealth of Pennsylvania has granted The Wistar Institute $4 million to fund COVID-19 research focused on understanding the impact of COVID-19 on certain at-risk populations and supporting the commonwealth’s preparation and emergency response planning for future pandemics.

11-Nov-2021 1:05 PM EST
Wistar Scientists Discover Sugar Molecule on HIV-infected Cell Plays Role in Evading Immune System — They Exploit as Weakness to Make More Effective “Natural Killers” Against HIV
Wistar Institute

A new Wistar Institute study shows how key features on the surface of HIV-infected cells help the disease evade detection by the immune system.


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