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Released: 15-Jul-2000 12:00 AM EDT
Link Between Common Infection and Stroke
NewYork-Presbyterian Hospital/Columbia University Medical Center

In a study published in the July issue of the journal Stroke, Dr. Mitchell S.V. Elkind found that people infected with Chlamydia pneumoniae were four-and-a-half times more likely to have suffered a first ischemic stroke than their counterparts who had not been exposed to the bacterium.

Released: 15-Jul-2000 12:00 AM EDT
Online Internet Nutrition Education -- Nutritionu.Com
NewYork-Presbyterian Hospital/Columbia University Medical Center

Columbia University's Institute of Human Nutrition will provide its expertise in nutrition education to the development of online course content for NutritionU.com. Courses will be designed to make practical and understandable nutrition information accessible to a broad audience.

Released: 15-Jul-2000 12:00 AM EDT
Center for Advanced Practice Nursing in Dominican Republic
NewYork-Presbyterian Hospital/Columbia University Medical Center

The first health center staffed exclusively by advanced practice nurses officially opened in the Dominican Republic city of Haina, 20 minutes from the capital Santo Domingo.

Released: 17-Jun-2000 12:00 AM EDT
Clue to Diabetes-Heart Disease Link
NewYork-Presbyterian Hospital/Columbia University Medical Center

An abnormality in a protein that helps clear fat from the blood may explain the greatly increased risk of heart disease that people with diabetes face, according to research published by Columbia University College of Physicians & Surgeons colleagues in the Journal of Clinical Investigation (6-00).

Released: 10-Jun-2000 12:00 AM EDT
Breathtaking Steps Reduce Asthma Deaths in Manhattan
NewYork-Presbyterian Hospital/Columbia University Medical Center

Columbia Presbyterian physicians have launched an aggressive project to help Washington Heights/Inwood residents with asthma control their illness and live symptom-free. The Columbia University Asthma Coalition is the first outreach project to target the largely Dominican-American community.

Released: 3-Jun-2000 12:00 AM EDT
From Evita to Rudy: Caring for the Famous
NewYork-Presbyterian Hospital/Columbia University Medical Center

An article in Lancet (6-1-00) explores the story of Evita and her doctor in the context of the mid-20th century, when doctors and families often kept patients in the dark about a diagnosis of cancer, and our present time of apparent openness and patient empowerment.

Released: 19-May-2000 12:00 AM EDT
Blocking Growth Factor Halts Tumor Advance in Mice
NewYork-Presbyterian Hospital/Columbia University Medical Center

Columbia University researchers have found that blocking the interaction of two naturally occurring molecules in tumor cells restricts the growth and spread of neoplasms in mice (Nature, 5-18-00).

Released: 12-May-2000 12:00 AM EDT
Cellular Defect at Root of Heart Failure
NewYork-Presbyterian Hospital/Columbia University Medical Center

A Columbia cardiologist has identified a molecular-level malfunction in patients with heart failure that can be repaired with existing treatments (Cell, 5-12-00).

Released: 2-May-2000 12:00 AM EDT
Stabilizing Progressive, Recurrent Prostate Cancer
NewYork-Presbyterian Hospital/Columbia University Medical Center

A study by Columbia Presbyterian researchers is the first of its kind to show a significant effect of a new class of drugs that may stabilize progressive, recurrent disease in patients with advanced prostate cancer; results will be presented at the annual meeting of the American Urological Association.

Released: 14-Apr-2000 12:00 AM EDT
Slowing Progression of Lou Gehrig's Disease
NewYork-Presbyterian Hospital/Columbia University Medical Center

Columbia researchers have participated in a study that points toward a potential treatment for amyotrophic lateral sclerosis, also known as Lou Gehrig's disease (Science, 4-14-00).

Released: 14-Apr-2000 12:00 AM EDT
Restored Immunity Protects AIDS Patients
NewYork-Presbyterian Hospital/Columbia University Medical Center

HIV-infected patients who respond well to antiretroviral drugs can safely forgo antibiotics to prevent certain opportunistic infections, demonstates a study led by a Columbia researcher (NEJM, 4-13-00).

Released: 25-Mar-2000 12:00 AM EST
Doctors Reinvent the Housecall
NewYork-Presbyterian Hospital/Columbia University Medical Center

Columbia University College of Physicians & Surgeons and SUNY Upstate Medical University have received a $28 million grant from the Health Care Financing Administration to bring health care into the homes of underserved rural and inner-city residents with diabetes.

Released: 25-Mar-2000 12:00 AM EST
Imaging Tests Elucidate Post-Stroke Recovery Process
NewYork-Presbyterian Hospital/Columbia University Medical Center

A Columbia Presbyterian neurologist has used an imaging technique called functional MRI to observe the parts of the brain activated in the stroke recovery process, shedding light on how the brain reorganizes itself to restore motor function (Stroke, 3-00).

Released: 25-Mar-2000 12:00 AM EST
Columbia Presbyterian Medical Center News Tips
NewYork-Presbyterian Hospital/Columbia University Medical Center

Levels of two blood factors associated with heart disease risk vary during the course of a woman's menstrual cycle, according to Columbia Presbyterian research.

Released: 23-Jul-1999 12:00 AM EDT
Cholesterol Associated with Dementia Following Stroke
NewYork-Presbyterian Hospital/Columbia University Medical Center

The "bad" form of cholesterol just got worse. Not only are high levels of the low-density lipoprotein (LDL) form of cholesterol a significant risk factor for heart disease, they also increase a person's risk of developing dementia after a stroke, according to a study.

Released: 23-Jul-1999 12:00 AM EDT
Injured Neurons Saved After Stroke
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers have shown that a hybrid molecule can mount a potent, double-sided defense to prevent the death of brain cells following a stroke. The strategy takes advantage of a surprising discovery that injured neurons flag themselves for destruction. The findings are reported in the July 23 issue of Science.

17-Jun-1998 12:00 AM EDT
Cyrstal Structure of GP120 Reveals HIV in Action
NewYork-Presbyterian Hospital/Columbia University Medical Center

In the long battle against AIDS, investigators have sought a viral Achilles heel by dissecting the precise molecular choreography that unfolds as HIV penetrates the linchpin-like T cells of the immune system. Now, a viral surface glycoprotein caught in the act of binding a CD4 T cell receptor -- graces the covers of both the June 18 issue of Nature and the June 19 issue of Science magazines.

31-May-1998 12:00 AM EDT
Relatives of People with Colorectal Polyps face Increased Risk for Colorectal Cancer
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers at the Columbia University College of Physicians & Surgeons have discovered that close relatives of individuals who have colon polyps (non-cancerous growths, or adenomas) face as high a risk of developing colorectal cancer as do people who have relatives with colorectal cancer itself. The research is reported in the June 1 issue of Annals of Internal Medicine.

Released: 29-May-1998 12:00 AM EDT
Researchers Discover Novel Gene Family Responsible for Pacemaker Activity in the Brain and Heart
NewYork-Presbyterian Hospital/Columbia University Medical Center

Two laboratories report the discovery that pacemaker activity in both the heart and the brain is mediated by a common family of novel genes. Pacemaker cells generate rhythmic, spontaneous electrical impulses that can control muscle activity, certain automatic functions such as breathing, and behavioral states, including arousal from sleep. Inappropriate pacemaker activity can lead to both inherited and acquired cardiac arrhythmias, and may also underlie various neurological disorders.

28-Apr-1998 12:00 AM EDT
Lungs Suffer From Growing Up in a Household of Smokers
NewYork-Presbyterian Hospital/Columbia University Medical Center

More solid evidence shows that growing up in a home around smokers has an adverse impact on lung function. The strongest correlation, highlighted in a new study, was with mothers who smoked. Girls seem to suffer more than boys, probably because girls spend more time around their mothers, researchers say.

26-Apr-1998 12:00 AM EDT
Defining the Inner-City Asthma Patient: a Basis for Change
NewYork-Presbyterian Hospital/Columbia University Medical Center

Inner-city residents frequently rely on the emergency room of their local hospital for asthma treatment, a practice that is not only expensive and inefficient but a sign that they are receiving insufficient help in managing the disease on their own. New research gives a detailed picture of these patients and the difficult challenges they pose.

26-Apr-1998 12:00 AM EDT
Family Coordinator Gives Families Confidence to Manage Asthma
NewYork-Presbyterian Hospital/Columbia University Medical Center

Hospitalization and death rates due to asthma among African-American and Latino children in New York City are four times higher than the national average. One contributing factor may be the failure of families to recognize the nature of the disease and develop skills for managing it. In partnership with family physicians, a family coordinator can help families overcome an often passive attitude toward asthma and build confidence to try to prevent or minimize symptoms themselves. That is the finding of a new study.

10-Mar-1998 12:00 AM EST
African Americans and Hispanics at Higher Risk for Alzheimer's Disease
NewYork-Presbyterian Hospital/Columbia University Medical Center

Although scientists have known for several years that the presence of the 4 form of the gene known as apolipoprotein-E (APOE) or APOE- 4 allele (gene variation), is associated with an increased risk of Alzheimer's disease among whites, the risk posed by the gene has not been so clear-cut among African Americans and Hispanics. Now, researchers from Columbia University College of Physicians & Surgeons have discovered that African Americans and Hispanics have an increased risk of Alzheimer's disease whether or not they carry the APOE- 4 allele. The discovery could lead to a better understanding of other genes or risk factors that may contribute to Alzheimer's disease.

18-Feb-1998 12:00 AM EST
Genetic Test For Alzheimer's May Improve Diagnostic Reliability
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers from Columbia University College of Physicians & Surgeons in collaboration with the National Institute on Aging (NIA) have discovered that the ApoE genetic test for Alzheimer's coupled with a thorough clinical evaluation may help to confirm the diagnosis.

Released: 13-Feb-1998 12:00 AM EST
New Research Suggest REM is about Eyes not Dreams
NewYork-Presbyterian Hospital/Columbia University Medical Center

A Columbia University researcher is "stirring" up conventional views on the function of rapid eye movement(REM) sleep. According to David Maurice, Ph.D., professor of ocular physiology in the Department of Ophthalmology at Columbia-Presbyterian Medical Center, REM sleep may have more to do with vision than with dreams.

Released: 12-Feb-1998 12:00 AM EST
Researchers Establish Parameters in Epilepsy
NewYork-Presbyterian Hospital/Columbia University Medical Center

Two or three unprovoked seizures may greatly increase the risk for more seizures and should be necessary criteria for diagnosing epilepsy, according to a study by researchers at Columbia University's College of Physicians and Surgeons. The study, published in the Feb 12 New England Journal of Medicine, establishes the first mathematically sound definition of epilepsy. The data could lead to a better understanding of seizure occurance and more appropriate treatment intervention.

Released: 29-Jan-1998 12:00 AM EST
Columbia Researchers Identify Gene for Inherited Baldness
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers at Columbia University College of Physicians & Surgeons have discovered the first human gene associated with hair loss. The new gene, called hairless, is linked to a severe form of inherited baldness and may be the trigger that turns on the entire human hair cycle. The discovery could lead to a better understanding of the hair cycle and, eventually, more effective treatments for various forms of hair loss.

Released: 1-Nov-1997 12:00 AM EST
Scientists Discover New Breast Cancer Susceptibility Gene
NewYork-Presbyterian Hospital/Columbia University Medical Center

New York, N.Y.--Mutations in the gene P-TEN can increase a woman's risk of breast cancer, according to scientists at Columbia University College of Physicians & Surgeons. The findings identify the third breast cancer susceptibility gene; the other two such genes are BRCA1 and BRCA2.

Released: 1-Nov-1997 12:00 AM EST
Diabetes Tipsheet
NewYork-Presbyterian Hospital/Columbia University Medical Center

Listed below are story ideas from the Columbia University Naomi Berrie Diabetes Center at the Columbia-Presbyterian MedicalCenter: 1) Holiday Treats & Diabetes: Can The Two Mix? 2) Giving The "Sweet Talk" On Diabetes Management, 3) No Such Thing As "A Touch Of Sugar," Especially In Pregnancy, 4)Columbia University Researchers "Gaining Ground" On Obesity And Diabetes

Released: 30-Oct-1997 12:00 AM EST
Gene Therapy Holds Promise For Sickle Cell Disease
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers from Columbia University College of Physicians & Surgeons have demonstrated the long-term transfer and high level long-term expression of the normal human beta globin gene in an animal model for the first time. The study, published in the Nov. 1 issue of Blood, may lead to gene therapy for the treatment of sickle cell disease and beta thalassemia, a related disorder.

16-Oct-1997 12:00 AM EDT
New Clue to Early Neuron Damage in Alzheimer's
NewYork-Presbyterian Hospital/Columbia University Medical Center

NEW YORK, N.Y., Oct. 15, 1997--Columbia University College of Physicians & Surgeons scientists have discovered a molecule, called ERAB, that provides an important clue to how early neuron damage may occur in Alzheimer's disease. The findings, published in the Oct. 16, issue of Nature, may lead to a intracellular target for the eventual treatment of the disease.

Released: 10-Oct-1997 12:00 AM EDT
New Device May Reduce The Incidence of Pneumonia Deaths
NewYork-Presbyterian Hospital/Columbia University Medical Center

The FDA has cleared a device invented at Columbia University College of Physicians & Surgeons that may reduce the incidence of pneumonia in thousands of elderly Americans and stroke patients who develop swallowing disorders. The device, called the Air Pulse Sensory Stimulator, measures sensory loss, or numbness, in the throat and voice box. Numbness in this region can increase the risk of food and secretions inadvertently going into the lungs and causing pneumonia.

Released: 30-Sep-1997 12:00 AM EDT
Preventing Latex Allergies Before They Attack
NewYork-Presbyterian Hospital/Columbia University Medical Center

Scientists at Columbia University have developed a new topical hand cream that may prevent the two most common latex allergy reactions-- sensitization to latex after prolonged exposure and contact dermatitis. Over 100,000 people in the United States are at risk for latex allergies, which causes itching and redness and in severe cases can lead to respiratory distress or even death.

Released: 13-Sep-1997 12:00 AM EDT
Study Launched to Test Selective Serotonin Reuptake Inhibitor in Children Suffering from Anxiety Disorders
NewYork-Presbyterian Hospital/Columbia University Medical Center

Nearly 12 million children and adolescents are diagnosed with emotional disorders, including anxiety and depression, in the United States each year. Yet because the medications used to treat these disorders are tested mainly on adults, little is known about their safety and efficacy in children and adolescents. Now, a new National Institutes of Health research center at Columbia University's College of Physicians & Surgeons aims to correct that deficit.

Released: 29-Aug-1997 12:00 AM EDT
Denatl Tips From Columbia University School Of Dental And Oral Surgery
NewYork-Presbyterian Hospital/Columbia University Medical Center

Story ideas from the Columbia University School of Dental and Oral Surgery's Guide to family Dental Care: 1) The Daily Grind, 2) Reducing The Neurosis About Halitosis, 3) Preparing Your Child For A Dental Visit

Released: 9-Aug-1997 12:00 AM EDT
Huntington's Disease Findings Pave Way For Potential Cure
NewYork-Presbyterian Hospital/Columbia University Medical Center

Nearly 20 years ago, Columbia University researchers observed brain cell changes in Huntington's disease patients. Today, the significance of those changes has finally been explained--and the new findings may lead to a treatment or cure for the progressive, degenerative brain disease.

Released: 7-Aug-1997 12:00 AM EDT
Statewide Initiative to Focus Doctors on End-of Life-Care
NewYork-Presbyterian Hospital/Columbia University Medical Center

The Associated Medical Schools of New York (AMS) announced a new initiative to focus the medical community on end-of-life care. It is estimated between 65-80 percent of all deaths occur in a hospital setting and that health care providers are the primary care-givers leading up to death. AMS will form a committee in a statewide collaborative effort to strengthen the training of future physicians on the issue of death and dying.

25-Jul-1997 12:00 AM EDT
Gene Therapy in Mice Delays Onset of Lou Gehrig's Disease (ALS)
NewYork-Presbyterian Hospital/Columbia University Medical Center

Scientists studying mice genetically engineered to develop familial amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, have found that the human gene Bcl-2 may delay the onset of ALS. The study appears in the July 24 issue of Science.

25-Mar-1997 12:00 AM EST
Brain, Breast, And Prostate Cancer Gene Identified
NewYork-Presbyterian Hospital/Columbia University Medical Center

NEW YORK, NY- Researchers at Columbia-Presbyterian Medical Center, in collaboration with Cold Spring Harbor Laboratory, have identified a new tumor suppressor gene, known as P-TEN, involved in a large percentage of brain, breast, and prostate cancers. The newly discovered tumor suppressor gene is one of more than a dozen known to be involved in a large variety of cancers. The discovery could lead to better tests for early detection and more effective treatments. The finding is reported in the March 28 issue of the journal, Science. Embargoed 3-27-97 4 p.m.

Released: 18-Jan-1997 12:00 AM EST
Mouse Mimics Disorder Leading to Heart Disease
NewYork-Presbyterian Hospital/Columbia University Medical Center

Researchers at Columbia-Presbyterian Medical Center and colleagues have developed as mouse model for the most common genetic cause of a lipid disorder associated with premature heart disease.


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