Clinical psychologist Aaron Fobian, Ph.D., has developed a therapy for this debilitating condition that she is now testing in a major NIH-sponsored clinical trial.
Although unproven, this novel sickle cell therapy serves as a potential cure. More measures need to be taken to determine long-term function and organ improvement.
Could superheroes make children participate in more dangerous play time? A UAB graduate research assistant is conducting a study to see whether superheroes could be related to adolescent injuries.
Lizzy Davis with the UAB Department of Nutrition Sciences shares the science of how to make your Thanksgiving worth gobbling up.
“Many people think that they don’t have the skills to be a good cook, but cooking is science,” Davis said.
About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.
The study, from UAB’s Institute for Arts in Medicine, shows that learning tricks in a magic camp can boost feelings of self-esteem and confidence in children and adolescents with disabilities.
In grateful recognition of a transformational $95 million lead gift from longtime University of Alabama at Birmingham supporter Marnix E. Heersink, M.D., the UAB School of Medicine will now be named the UAB Marnix E. Heersink School of Medicine.
Health Promoting Universities are an international community that aspires to transform the health and sustainability of current and future societies, strengthen communities, and contribute to the well-being of people, places and the planet.
Two nutrition researchers at UAB claim that hunger cues go well beyond your stomach’s rumbling and grumbling — it has more to do with your overall mindfulness.
Arnoldo Vasquez Hernandez was pinned under an oak tree that fell on his house during a tornado in January 2021, requiring a rare, in-the-field amputation. After being fitted for a prosthetic leg, he is now able to take his first steps in nearly five months.
A comprehensive health-screening program in rural northern KwaZulu-Natal, South Africa, has found a high burden of undiagnosed or poorly controlled non-communicable diseases, according to a study published in The Lancet Global Health.
A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.
Evaluation of three vaccine candidates during the COVID-19 pandemic fell to 12 experts of the federally appointed COVID-19 Vaccine Data and Safety Monitoring Board. This team has now taken the unusual step of publishing details of their review process in The Journal of Infectious Diseases.
For anyone experiencing changes in vision, a comprehensive eye exam is essential. However, because the changes related to cataracts can be slow and subtle, it is better not to wait until your sight is significantly affected.
For many, the arrival of COVID-19 mRNA vaccines in less than a year is, quite literally, unbelievable. That skepticism feeds hesitancy to take the vaccines. But development of mRNA vaccines against COVID-19 is no overnight success. In fact, they have a remarkable backstory stretching back decades.
The UAB undergraduate Student Affiliates group of the American Chemical Society has been awarded its highest recognition for the 2019-2020 academic year, Outstanding Student Chapter Award.
Coding with Physics workshops train teachers to incorporate storytelling, supportive teamwork, productive failure and other video game techniques to engage teens in science.
A single intranasal dose of a COVID-19 vaccine candidate created by Altimmune Inc. provides sterilizing immunity in the lungs of vaccinated animals. In contrast, non-vaccinated animals showed dense pulmonary infection and disease following infection with the virus that causes COVID-19.
A new study published in the Journal of Molecular and Cellular Cardiology by University of Alabama at Birmingham researchers shows that an increase in the consumption of branch chain amino acids later in the day could result in a negative effect on cardiovascular health.
New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.
Masking can prevent more than COVID-19 from spreading this spring: Allergic rhinitis symptoms have shown to be significantly reduced with facemask usage during the pandemic.
Researchers at UAB have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer. The findings indicate that an adhesive cell surface protein known as N-cad may be key in overcoming glioblastoma’s resistance to radiation therapy.
Two new studies investigating child maltreatment during the COVID-19 pandemic reveal "concerning results" that confirm warning signs seen early in the pandemic, according to researchers at UAB and the University of Michigan.
A new interactive dashboard from UAB and PathCheck Foundation will enable users to see the quantity and location of vaccines distributed across the country and world in real time.
PAGER-CoV is a database packed with nearly 12,000 (so far) pieces of genetic information on the SARS-CoV-2 virus, information that researchers and physicians can use to tailor treatments against the disease.
Researchers inactivated the gene for CHD7 — whose mutation causes congenital birth defects — in mouse embryos, and then rigorously probed how this change in developing cardiac neural crest cells caused severe defects in the outflow tract and great arteries, leading to perinatal lethality.
Maryland-based Altimmune Inc., a clinical stage biopharmaceutical company, has submitted an Investigational New Drug, or IND, application to the United States Food and Drug Administration to commence a Phase 1 clinical study of its single-dose intranasal COVID-19 vaccine candidate, AdCOVID.
Mask orders. Constant cleaning. Quarantine. The COVID-19 pandemic has completely changed how many people live. This can be especially true for older adults. As one of the most at-risk populations for COVID-related complications, many older adults have been forced to isolate themselves, causing decreased physical and mental activity.
Researchers have discovered a previously undescribed set of neurons called saccade-vergence burst neurons that help control our eyes as they view in three-dimensional space. Models had predicted the existence of such neurons, which are in the mid-brain’s central mesencephalic reticular formation.
During the COVID-19 pandemic, the sickest patients at the University of Alabama at Birmingham Hospital have had their troubles eased, however briefly, thanks to an innovative musical project. Helping those patients recover — and keeping their spirits up amid the isolation the virus requires — is the motivation for the project, an effort between UAB health care staff and the Alabama Symphony Orchestra.
People with multiple depressive symptoms have an increased risk for stroke, with new findings showing that individuals who scored higher on a test designed to measure depressive symptoms had a higher stroke risk than those with lower scores.
Transplanting cadaver pancreatic islets is a promising therapy for Type 1 diabetes, but a reactivated autoimmunity means low graft viability after five years. Research now shows that a protective coating of two biopolymers can delay allograft and autoimmune-mediated rejection in mouse models of T1D.
A new study published in the Mayo Clinic Proceedings: Innovations, Quality & Outcomes by University of Alabama at Birmingham researchers showed that Black individuals have a disproportionately higher COVID-19 mortality burden across all of the United States, which is driven by a high incidence of COVID-19 infection. They found that there are key geographic differences in the distribution of health determinants and COVID-19 mortality patterns.
For many rural Americans, especially those in the South or Southeastern areas of the country, it is taking longer to get to a hospital. Delays in reaching appropriate health care facilities could have a profound negative effect in cases of medical emergency.
An inhaled monoclonal antibody treatment against the SARS-CoV-2 virus may lead to self-administered therapy for COVID-19, according to preclinical tests. It was discovered at UAB and the Texas Biomedical Research Institute, and it has been licensed for development to Aridis Pharmaceuticals.
A COVID-19 vaccine candidate that underwent extensive preclinical testing this spring and summer shows potent preclinical immune responses — including several that distinguish it from other COVID-19 vaccine approaches — according to a preprint deposited in the BioRxiv repository.
Reports that some young athletes testing positive for COVID-19 also had increased rates of heart swelling have concerned sports medicine physicians around the country, concerned about the possible impact of myocarditis, a potentially fatal heart condition.
Research in pigs shows that using the exosomes naturally produced from a mix of heart muscle, endothelial and smooth muscle cells — all derived from human induced pluripotent stem cells — yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells.
Researchers combined a lung-epithelial cell host interactome with a SARS-CoV-2 interactome. Network biology analysis of this human/SARS-CoV-2 interactome revealed potential molecular mechanisms of pathogenesis for SARS-CoV-2, the virus responsible for the COVID-19 pandemic.