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Released: 1-Feb-2024 3:05 PM EST
UHN and YouTube Health Join Forces to Deliver Trusted Health Information to Canadians
University Health Network (UHN)

University Health Network (UHN), Canada’s #1 hospital and a leading healthcare institution dedicated to providing exceptional patient care & advancing biomedical research, and YouTube Health, a global initiative committed to making high-quality health information available, are thrilled to announce a strategic partnership aimed at delivering timely, reliable & accurate health information to Canadians.

Released: 30-Nov-2023 11:00 AM EST
To safely deploy generative AI in health care, models must be open source
University Health Network (UHN)

Large-language models could soon become essential tools for diagnosing diseases. To protect people’s privacy, medical professionals must drive the development and deployment of such models.

   
Newswise: Andrea_Furlan.jpg
Released: 29-Nov-2023 12:05 PM EST
Chronic pain program at Toronto Rehab awarded for its ECHOing effects
University Health Network (UHN)

In 2014, Dr. Andrea Furlan, a physician at Toronto Rehab and a leader in chronic pain treatment, had a vision: to bring together a group of experts who could equip health care professionals in the community with the knowledge they'd need to provide proper pain treatment.

Newswise: Tiano_Kosyachkova.jpg
Released: 29-Nov-2023 12:05 PM EST
Living – and thriving – without a stomach
University Health Network (UHN)

When Teresa Tiano had her stomach removed, she didn't know how she was going to survive.

Newswise: Tartaglia_Ozzoude.jpg
Released: 29-Nov-2023 11:05 AM EST
Matters of the brain
University Health Network (UHN)

​Researchers at UHN's Krembil Brain Institute have uncovered links between structural changes in the brain and neuropsychiatric symptoms of various neurodegenerative diseases.

Newswise:Video Embedded study-using-novel-approach-for-glioblastoma-treatment-shows-promising-results-extending-survival
VIDEO
Released: 16-May-2023 8:05 PM EDT
Study using novel approach for glioblastoma treatment shows promising results, extending survival
University Health Network (UHN)

A new international study published in and presented as a late-breaking abstract at the American Association of Neurological Surgeons (AANS) annual conference, shows great promise for patients with glioblastoma. Drs. Farshad Nassiri and Gelareh Zadeh, neurosurgeons and scientists at the University Health Network (UHN) in Toronto, published the results of a Phase 1/2 clinical trial investigating the safety and effectiveness of a novel therapy which combines the injection of an oncolytic virus – a virus that targets and kills cancer cells – directly into the tumour, with intravenous immunotherapy.

Newswise: Researchers identify a potential new therapeutic target in Parkinson's disease
Released: 19-Apr-2023 12:05 PM EDT
Researchers identify a potential new therapeutic target in Parkinson's disease
University Health Network (UHN)

In a study published in Nature Communications, a team led by Krembil Brain Institute at UHN Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease. In the disease, a protein called α-synuclein (a-syn) accumulates in the brain and leads to cell death.

Released: 11-Apr-2023 2:10 PM EDT
Takeda licenses small molecule developed by Krembil Brain Institute researchers, targeting tau protein implicated in Alzheimer’s disease
University Health Network (UHN)

Global pharmaceutical company Takeda has agreed to exclusively license a group of small molecules that target tau – a protein in which misfolding and aggregation are believed to be a cause of Alzheimer’s disease.

Newswise: Single-dose treatment reduces risk of COVID-19 hospitalization by half for high-risk patients in a largely vaccinated population
8-Feb-2023 12:20 PM EST
Single-dose treatment reduces risk of COVID-19 hospitalization by half for high-risk patients in a largely vaccinated population
University Health Network (UHN)

A single-dose of the antiviral drug peginterferon lambda reduced by half the risk of hospitalization or a visit to the Emergency Department due to COVID-19, according to a study published today in the New England Journal of Medicine.

Newswise: Dr. Jaideep Bains to join UHN as new Director of the Krembil Research Institute
Released: 3-Oct-2022 11:05 AM EDT
Dr. Jaideep Bains to join UHN as new Director of the Krembil Research Institute
University Health Network (UHN)

(Toronto, Oct. 3, 2022) – University Health Network (UHN) is pleased to announce that Dr. Jaideep Bains will be joining our team as the new Director of the Krembil Research Institute. The Krembil Research Institute, one of the principal institutes within UHN, comprises the Krembil Brain Institute, the Schroeder Arthritis Institute and the Donald K.

Newswise: Great Actions Leave a Mark campaign celebrates the Gift of Life through Living Organ Donation
7-Sep-2022 2:00 PM EDT
Great Actions Leave a Mark campaign celebrates the Gift of Life through Living Organ Donation
University Health Network (UHN)

UHN’s Ajmera Transplant Centre and The Centre for Living Organ Donation announce today the launch of a new campaign, Great Actions Leave a Mark, www.greatactions.ca. The campaign showcases through artistic photos and video, the stories and scars (the mark) from 39 living organ donors and transplant recipients across Canada.

Newswise: Anonymous $11 million gift to support and expand neurofibromatosis research at UHN's Krembil Brain Institute
Released: 17-May-2022 1:25 PM EDT
Anonymous $11 million gift to support and expand neurofibromatosis research at UHN's Krembil Brain Institute
University Health Network (UHN)

Anonymous $11M donation will go toward research, care for Neurofibromatosis patients

Newswise:Video Embedded living-donation-opens-new-doors-for-colorectal-cancer-patients-in-need-of-liver-transplants
VIDEO
28-Mar-2022 4:00 PM EDT
Living Donation Opens New Doors for Colorectal Cancer Patients in Need of Liver Transplants
University Health Network (UHN)

A study published in the Journal of the American Medical Association Surgery is the first in North America to demonstrate that living-donor liver transplant is a viable option for patients who have systemically controlled colorectal cancer and liver tumors that cannot be surgically removed.

6-Dec-2021 4:00 AM EST
Boys 10 times more likely to get HPV vaccine in provinces where programs are publicly funded
University Health Network (UHN)

Boys are 10 times more likely to be vaccinated against human papillomavirus (HPV) in provinces where the vaccine is publicly funded than in places where it is not, according to a new study published by a researcher at the Princess Margaret Cancer Centre and colleagues at McGill University, Université de Montréal, and the Jewish General Hospital.

Released: 17-Nov-2021 4:05 PM EST
Connecting the Dots for Health Data
University Health Network (UHN)

The Canadian Distributed Infrastructure for Genomics (CanDIG) is a collaboration of computer scientists, AI specialists, clinicians, and geneticists working together to enable studies needed to address the health challenges faced by Canadians.

Newswise:Video Embedded university-health-network-reported-top-canadian-research-commercialization-institution-for-2nd-year-running
VIDEO
Released: 1-Nov-2021 11:05 AM EDT
University Health Network reported top Canadian research commercialization institution for 2nd year running
University Health Network (UHN)

According to the latest Association of University Technology Managers (AUTM) North American Annual Licensing Survey, the University Health Network (UHN) ranks as the #1 research commercialization institution in Canada for the second year running according to gross licensing revenue from the research it has commercialized.

Newswise:Video Embedded new-study-reveals-heart-patients-orphaned-following-aortic-dissection-repair-despite-ongoing-risk-of-complications-and-death
VIDEO
Released: 27-Oct-2021 11:25 AM EDT
New study reveals heart patients "orphaned" following aortic dissection repair despite ongoing risk of complications and death
University Health Network (UHN)

A new study from the Peter Munk Cardiac Centre reveals that patients who survive an aortic dissection often fail to receive comprehensive post-surgical follow-up care leaving them vulnerable to a lifetime of sustained risk.

Newswise: Discovery of a potential new therapy for inflammatory arthritis
Released: 20-Oct-2021 2:25 PM EDT
Discovery of a potential new therapy for inflammatory arthritis
University Health Network (UHN)

Ankylosing spondylitis is a painful and inflammatory form of axial spondyloarthritis (SpA) which affects 1-2% of Canadians and causes inflammation in the spine, joints, eyes, gut and skin. In a new paper recently published in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute at UHN have made a discovery that could lead to new treatments for SpA.

Newswise: World-first: experts at UHN, Sinai Health and SickKids develop plan to save critically ill mother and her baby
Released: 4-Oct-2021 8:25 AM EDT
World-first: experts at UHN, Sinai Health and SickKids develop plan to save critically ill mother and her baby
University Health Network (UHN)

Physicians recommend that patients with pulmonary hypertension avoid pregnancy, given the high risk of death for the mother and baby. However, Candice Cruise was unaware of her condition until she reached 21 weeks of pregnancy.

Newswise: Princess Margaret Cancer Centre researchers refine test to achieve 'ultrasensitive' detection of HPV in the bloodstream
Released: 27-Sep-2021 2:10 PM EDT
Princess Margaret Cancer Centre researchers refine test to achieve 'ultrasensitive' detection of HPV in the bloodstream
University Health Network (UHN)

Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.

Released: 20-Aug-2021 6:00 PM EDT
Former Medical Director at Princess Margaret Cancer Centre to lead new commission on global cancer care
University Health Network (UHN)

Dr. Mary Gospodarowicz, former Medical Director of the Princess Margaret Cancer Centre, will co-chair a new The Lancet Commission on cancer and health systems as it examines and makes recommendations to improve global cancer care and health systems.

10-Aug-2021 5:20 PM EDT
World-First COVID Vaccine Booster Randomized Clinical Trial in Transplant Patients Proves Third Shot Is Very Effective
University Health Network (UHN)

The study enrolled 120 transplant patients between May 25th and June 3rd. None of them had COVID previously and all of them had received two doses of the Moderna vaccine. Half of the participants received a third shot of the vaccine (at the 2-month mark after their second dose) and the other half received placebo. The primary outcome was based on antibody level greater than 100 U/ml against the spike protein of the virus. In the placebo group - after three doses (where the third dose was placebo), the response rate was only 18% whereas in the Moderna three-dose group, the response rate was 55%.

11-Aug-2021 2:40 PM EDT
World-first COVID vaccine booster randomized clinical trial in transplant patients proves third shot is very effective
University Health Network (UHN)

The study enrolled 120 transplant patients between May 25th and June 3rd. None of them had COVID previously and all of them had received two doses of the Moderna vaccine. Half of the participants received a third shot of the vaccine (at the 2-month mark after their second dose) and the other half received placebo. The primary outcome was based on antibody level greater than 100 U/ml against the spike protein of the virus. In the placebo group - after three doses (where the third dose was placebo), the response rate was only 18% whereas in the Moderna three-dose group, the response rate was 55%.

2-Aug-2021 8:00 AM EDT
Princess Margaret Cancer Centre Researchers Discover Key Stem Cell Dormancy Mechanism Which Could Help Unlock Future Cancer Treatments
University Health Network (UHN)

Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.

Released: 13-Jul-2021 4:00 PM EDT
Study Finds Disparity in Pay for Female Ophthalmologists in Ontario, Canada
University Health Network (UHN)

A team led by researchers and clinicians from the Donald K. Johnson Eye Institute, part of the Krembil Research Institute at University Health Network (UHN), studied 22,389 Ontario physicians across three decades and found a significant payment gap between female and male ophthalmologists even after accounting for age, and some practice differences. This disparity was more pronounced among ophthalmologists when compared to other surgical, medical procedural and medical non-procedural specialty groups.

8-Jul-2021 2:05 PM EDT
Concussion calculator predicts recovery time, risk of long-term symptoms
University Health Network (UHN)

The ability to determine who will recover quickly, and who will continue to suffer from symptoms has largely eluded the medical community. Until now.

Released: 4-Jun-2021 12:20 PM EDT
UHN announces first-in-Canada Social Medicine Modular Housing in Parkdale, in partnership with the City and United Way Greater Toronto
University Health Network (UHN)

University Health Network (UHN) and the Gattuso Centre for Social Medicine, in partnership with the City of Toronto and United Way Greater Toronto (UWGT), are creating what is believed to be the first of its kind in Canada, Social Medicine Supportive Housing site in Parkdale, Toronto.

3-Jun-2021 10:00 AM EDT
AI outperforms humans in creating cancer treatments, but do doctors trust it? It depends!
University Health Network (UHN)

The impact of deploying Artificial Intelligence (AI) for radiation cancer therapy in a real-world clinical setting has been tested by Princess Margaret researchers in a unique study involving physicians and their patients.

   
7-May-2021 1:00 PM EDT
Turning a pancreatic cancer cell’s addiction into a death sentence
University Health Network (UHN)

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them. Led by Princess Margaret Cancer Centre Scientist Dr. Marianne Koritzinsky, researchers showed that about half of patient-derived pancreatic cancer cell lines are highly dependent or “addicted” to the protein peroxiredoxin 4 (PRDX4), as a result of the altered metabolic state of the cancer cell. This addiction, which is vital for the cancer cell's survival, makes it a precise, potential target against the cancer.

13-Apr-2021 9:05 PM EDT
Triple Combination Therapy Shows Promise Against a Rare Deadly Asbestos Cancer
University Health Network (UHN)

Combining immune-boosting drugs with radiation and surgery increased the survival and anticancer immune response in mouse models of mesothelioma in preclinical research by Princess Margaret Cancer Centre researchers.



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