In the first such procedures in Tennessee, Vanderbilt University Medical Center has successfully used technology to bring two donor hearts that stopped beating back to life before transplanting them into patients.
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.
A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.
The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Changecompetition for a single $100 million grant to help solve one of the world’s most critical societal challenges.
Most Tennessee infants exposed to hepatitis C at birth are not later tested to see if they acquired the virus, according to a study by researchers at Monroe Carell Jr. Children’s Hospital at Vanderbilt and the Vanderbilt Center for Child Health Policy.
Emergency Medicine and Trauma Surgery researchers at Vanderbilt University Medical Center (VUMC) are joining the Nashville Fire Department and nearly two dozen emergency medical service agencies across the country in a Department of Defense (DOD)-funded clinical trial aimed at improving survival with breathing techniques used to keep patients alive at the scene of a trauma.
VICC is the first cancer center to enroll a patient in a clinical trial for this new technology developed by SQZ Biotechnologies of Watertown, Massachusetts. The investigational product is generated from the company’s technology that uses high-speed cell deformation to squeeze cells, creating a temporary disruption of their membranes and offering a window for the insertion of tumor antigens.
High levels of protein in a patient’s urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function.
The CEASAR (Comparative Effectiveness Analysis of Surgery and Radiation for Localized Prostate Cancer) study, coordinated by Vanderbilt University Medical Center, is a multi-site research study conducting long-term followup on men who were diagnosed with localized prostate cancer between 2011 and 2012.
The benefits of fetal surgery to repair spina bifida, a procedure pioneered at Vanderbilt University Medical Center (VUMC) in 1997, continue through school age, a National Institutes of Health (NIH) study reports today in the journal Pediatrics.
A molecule produced by the brain that activates the same receptors as marijuana is protective against stress by reducing anxiety-causing connections between two brain regions, Vanderbilt University Medical Center researchers report.
An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms: cleft palate, cataracts, tooth abnormality, intellectual disability, facial dysmorphism and ADHD. The investigators report in Nature Medicine that the new disease is caused by a defect in collagen secretion.
Shon Dwyer, MBA, RN, executive director of Michigan Medicine’s (University of Michigan, Ann Arbor) University Hospital and Frankel Cardiovascular Center, has been named the new president of Vanderbilt University Adult Hospital (VUAH). She will join Vanderbilt University Medical Center on March 2.
In Southern states that expanded their Medicaid programs under the Affordable Care Act, adults experienced lower rates of decline in both physical and mental health, according to research published this month in the journal Health Affairs.
One of the nation’s largest health information technology companies, Epic Systems Corp., based in Verona, Wisconsin, has released a system update that stands to advance prevention of ICU delirium and improve patient outcomes.
The new report is designed to be a comprehensive reference for organizational leaders, health care professionals, data analysts, model developers and those who are working to integrate machine learning into health care, said Vanderbilt University Medical Center’s Michael Matheny, MD, MS, MPH, Associate Professor in the Department of Biomedical Informatics, and co-editor of AI in Healthcare: The Hope, The Hype, The Promise, The Peril.
The National Institutes of Health (NIH) has selected Joshua C. Denny, MD, MS, vice president of Personalized Medicine at Vanderbilt University Medical Center (VUMC), to be the Chief Executive Officer of the federal All of Us Research Program.
While it can be difficult to decipher symptoms, Michele Walsh, MD, assistant professor of Pediatrics and medical director of the Pediatric Emergency Department at Children's Hospital, offers tips on when it is best to bring a child to an emergency department (ED) versus making a call or visit to the family pediatrician.
The popular heartburn drug ranitidine, commonly known as Zantac, was voluntarily recalled due to the contamination of a human carcinogen that could potentially cause cancer. The recall includes oral tablets, capsules, and syrup.
According to the Centers for Disease Control and Prevention (CDC), each year an estimated 48 million people, about one in six, contract a foodborne illness. Approximately 128,000 require hospitalization, and 3,000 cases are fatal.
Researchers from the Vanderbilt Bill Wilkerson Center and the Marcus Autism Center at Emory University School of Medicine are partnering to study musical rhythm synchronization as a part of social development and how it’s disrupted in children with autism spectrum disorder (ASD) in hopes of developing music interventions for improving social communication.
A new study by Vanderbilt-Ingram Cancer Center (VICC) researchers published in Clinical Cancer Research, a journal of the American Association for Cancer Research, indicates that a lower threshold is needed for male patients to predict mortality using the genetic assay, Oncotype DX®, a commercial diagnostic test. The study’s lead author is Fei Wang, MD, PhD, a visiting research fellow at Vanderbilt University, and its senior author is Xiao-Ou Shu, MD, PhD, MPH, Ingram Professor of Cancer Research and associate director for Global Health and co-leader of the Cancer Epidemiology Research Program at VICC.
The procedure, called Endobronchial Lung Volume Reduction (ELVR), is for patients with emphysema who have hyperinflated lungs. These patients can inhale but have difficulty exhaling because air trapped in their lungs causes them to become hyperinflated. Until now, such patients were typically treated with inhalers, lung surgery to reduce volume or lung transplants.
Kathryn Edwards, MD, who holds the Sarah H. Sell and Cornelius Vanderbilt Endowed Chair in Pediatrics and is a professor of Pediatrics at Vanderbilt University School of Medicine, is the recipient of the 2020 John Howland Award, the highest honor given by the American Pediatric Society (APS).
When the Nashville Predators hockey team hits the ice Saturday, Nov. 2, the players will take on an important opponent: childhood cancer.
The Hockey Fights Cancer game against the New York Rangers will raise funds for the 365 Pediatric Cancer Fund at Monroe Carell Jr. Children’s Hospital at Vanderbilt. The team and the players will also honor one of the hospital’s most passionate advocates, Luke Gregory, chief executive officer for Children’s Hospital, who died Oct. 18 after a battle with non-Hodgkin’s lymphoma.
Meg Rush, MD, MMHC, who began her career at Vanderbilt University Medical Center more than three decades ago, has been named interim president of Monroe Carell Jr. Children’s Hospital at Vanderbilt, effective immediately.
Clinician burnout is affecting between one-third and one-half of all of U.S. nurses and physicians, and 45 to 60% of medical students and residents, according to a National Academy of Medicine (NAM) report released today.
A new multisite study funded by the National Institute on Aging will examine whether co-occurring Alzheimer’s disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.
Among the 30 million U.S. adults with Type 2 diabetes, 20% have impaired kidney function. In patients like this, metformin, the recommended first-line drug therapy for Type 2 diabetes, is associated in the new study with 20 percent decreased risk of major adverse cardiovascular events when compared to a class of common diabetes drugs called sulfonylureas.
After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.
A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25% in a study published today in the New England Journal of Medicine (NEJM).
Researchers at Vanderbilt University Medical Center (VUMC) are partnering with the Dutch biopharmaceutical firm Batavia Biosciences and Nashville-based IDBiologics to bring to the clinic a highly potent Zika virus neutralizing antibody they isolated three years ago.
The number of teens and young adults treated for severe respiratory injury after e-cigarette use is increasing at Monroe Carell Jr. Children’s Hospital at Vanderbilt, which is consistent with a nationwide trend that led to a recent communication to physicians from the Centers for Disease Control and Prevention (CDC).
Heavy cigarette smokers with at least a 20 pack-year smoking history can reduce their risk of cardiovascular disease (CVD) by 39% within five years if they quit, according to a study published today in the Journal of the American Medical Association (JAMA).
In November 2018 Dyer underwent peripheral nerve surgery at the Nashville Veterans Affairs Hospital with the goal of relieving her chronic migraine headaches. The outpatient surgery is now also being offered by the same team of plastic surgeons at Vanderbilt University Medical Center.
Leaders of Vanderbilt University Medical Center (VUMC) today announced completion of the acquisition of Tennova Healthcare-Lebanon, a two-campus facility licensed for 245 beds, from subsidiaries of Community Health Systems, Inc. (CHS). Terms of the transaction will remain confidential.
The Vanderbilt Eye Institute (VEI) has received a $10 million gift — the Institute’s largest to date — that will fund regenerative visual neuroscience research to develop transformative therapies for eye diseases.
SUDEP occurs in about 1-2 per 1,000 patients with chronic epilepsy and 3-9 per 1,000 in those with severe, refractory seizures, though its frequency is difficult to calculate. It is most common in patients 20 to 40 years old.
The results, published July 22 in Nature Medicine, are the latest findings by VICC researchers chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies. The researchers have previously identified myocarditis, pneumonitis, hepatitis, colitis and vasculitis as possible complications. Checkpoint inhibitors unleash the immune system to attack cancer, but they may also spur an attack on organs, resulting in inflammation that can, in most cases, be effectively treated with steroids.