Latest News from: Georgetown Lombardi Comprehensive Cancer Center

Filters close
20-Jan-2020 9:00 AM EST
Gut Bacteria May be One Culprit for Increase of Colorectal Cancer in Younger People
Georgetown Lombardi Comprehensive Cancer Center

A bacteria typically linked to periodontal disease, Fusobacterium nucleatum (F. nuc), could play an important role in the rising incidence of colorectal cancer in people under the age of 45. Another type of bacteria, Moraxella osloensis, has been found in colorectal cancer tumors at a nearly four-fold higher rate in people over 75 than in those under 45 years of age, pointing out how differences in the bacteria that comprise what is known as the body’s microbiome could affect cancer outcomes to varying degrees. These are the preliminary findings of an ongoing study that will be presented at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco from January 23-25, 2020.

Released: 20-Jan-2020 10:50 AM EST
New Drug Prevents Liver Damage, Obesity and Glucose Intolerance in Mice on High-Fat Diet
Georgetown Lombardi Comprehensive Cancer Center

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body’s glucose balance.

Released: 8-Dec-2019 2:05 PM EST
Palbociclib is Safe for Women with Advanced Breast Cancer Who Have Unique Gene Alteration
Georgetown Lombardi Comprehensive Cancer Center

When FDA approved palbociclib (Ibrance ®), there was very little data about the safety of this drug in people with benign ethnic neutropenia (BEN), which is common in women of color. Some of these women didn’t qualify for the clinical trials because of the required blood count, which is lower in women with BEN.

Newswise: Brain Studies Show Chronic Fatigue Syndrome and Gulf War Illness are Distinct Conditions
18-Oct-2019 1:55 PM EDT
Brain Studies Show Chronic Fatigue Syndrome and Gulf War Illness are Distinct Conditions
Georgetown Lombardi Comprehensive Cancer Center

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise). Now, neuroscientists at Georgetown University Medical Center have evidence, derived from human brain studies, that GWI and CFS are two distinct disorders that affect the brain in opposing ways.

18-Oct-2019 7:05 AM EDT
Aggressive Form of Breast Cancer Influenced by Dual Action of Genes and RNA
Georgetown Lombardi Comprehensive Cancer Center

Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.

Released: 8-Oct-2019 7:05 AM EDT
Georgetown Offers Multiple Clinical Trials for People with Lewy Body Dementia
Georgetown Lombardi Comprehensive Cancer Center

Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson’s and Alzheimer’s disease.

29-Aug-2019 1:05 PM EDT
Georgetown Tobacco Control Expert Outlines Motivations of Altria-Juul Deal and Its Public Health Impact
Georgetown Lombardi Comprehensive Cancer Center

The pending deal for Altria to purchase 35% of Juul Labs should serve as a “wake-up call” for the careful monitoring of competition in the nicotine delivery market, and for evaluating how regulations and policies impact cigarette and non-cigarette firms selling alternative nicotine delivery products, says a Georgetown University professor.

Newswise: Revealing the Molecular Engine That Drives Pancreatic Cancer Provides Ways to Turn It Off
16-Aug-2019 12:05 PM EDT
Revealing the Molecular Engine That Drives Pancreatic Cancer Provides Ways to Turn It Off
Georgetown Lombardi Comprehensive Cancer Center

Researchers have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma—the most common and also the most lethal form of pancreatic cancer.

Newswise: Bacterial Resistance to Two Critical Antibiotics Widespread in Southeast Asia
Released: 12-Aug-2019 11:05 AM EDT
Bacterial Resistance to Two Critical Antibiotics Widespread in Southeast Asia
Georgetown Lombardi Comprehensive Cancer Center

Resistance to two critical antibiotic types, one a “drug of last resort” when all others fail against some “superbugs,” are widely distributed in Southeast Asia, raising the risk of untreatable infections, say a team of investigators led by Georgetown University Medical Center.

Newswise: Indoor Tanning May Be an Addiction Abetted by Both Genetic and Psychiatric Factors
11-Jun-2019 6:05 AM EDT
Indoor Tanning May Be an Addiction Abetted by Both Genetic and Psychiatric Factors
Georgetown Lombardi Comprehensive Cancer Center

A combination of elevated symptoms of depression along with modifications in a gene responsible for dopamine activity, important to the brain’s pleasure and reward system, appear to influence an addiction to indoor tanning in young, white non-Hispanic women.

Newswise: Labels of U.S. Probiotic Products Lacking, Researchers Find
3-Jun-2019 4:50 AM EDT
Labels of U.S. Probiotic Products Lacking, Researchers Find
Georgetown Lombardi Comprehensive Cancer Center

When it comes to buying probiotics, most product labels do not give consumers enough information to make an informed decision, according to a research team led by Georgetown University Medical Center.

Released: 30-May-2019 5:00 AM EDT
Patient Groups Untested in Cancer Immunotherapy Trials Found to Also Benefit
Georgetown Lombardi Comprehensive Cancer Center

Cancer patients previously excluded and underrepresented in immunotherapy clinical trials, such as African Americans and patients with HIV or viral hepatitis, actually benefit at the same rate as patients tested in the clinical trials, according to a Georgetown-led study to be presented at the 2019 ASCO Annual Meeting in Chicago.

Released: 30-May-2019 5:00 AM EDT
Significant “Knowledge Gap” Exists in Use of Genetic Testing to Decide Cancer Treatment
Georgetown Lombardi Comprehensive Cancer Center

A survey conducted by Georgetown investigators found a significant knowledge and practice gap among community oncologists in the understanding and usage of genetic testing in determining patients' treatment plans and potential clinical trial outcomes.

Newswise: Use of Genetic Testing in Women Diagnosed with Breast Cancer Decreases Cost of Care Nationwide
19-Apr-2019 10:30 AM EDT
Use of Genetic Testing in Women Diagnosed with Breast Cancer Decreases Cost of Care Nationwide
Georgetown Lombardi Comprehensive Cancer Center

A new study suggests that Oncotype DX-guided treatment could reduce the cost for the first year of breast cancer care in the U.S. by about $50 million (about 2 percent of the overall costs in the first year). The study by Georgetown Lombardi Comprehensive Cancer Center and National Cancer Institute researchers was published April 24, in JNCI.

14-Apr-2019 5:05 PM EDT
Large Federal Program Aimed at Providing Better Health Care Underfunds Primary Care
Georgetown Lombardi Comprehensive Cancer Center

Despite a mandate to help patients make better-informed health care decisions, a ten-year research program established under the Affordable Care Act has funded a relatively small number of studies that examine primary care, the setting where the majority of patients in the U.S. receive treatment.

Newswise: Rare but Important Gene Target Found in Many Tumor Types, Suggesting New Therapy Possible
12-Apr-2019 2:00 PM EDT
Rare but Important Gene Target Found in Many Tumor Types, Suggesting New Therapy Possible
Georgetown Lombardi Comprehensive Cancer Center

A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types.

Newswise: @LombardiCancer-Led Study Leads to First FDA-Approved Drug in Decades to Improve Survival in Small Cell Lung Cancer
Released: 18-Mar-2019 8:05 PM EDT
@LombardiCancer-Led Study Leads to First FDA-Approved Drug in Decades to Improve Survival in Small Cell Lung Cancer
Georgetown Lombardi Comprehensive Cancer Center

The U.S. Food and Drug Administration’s approval today of atezolizumab (Tecentriq®, Genentech) in combination with chemotherapy (carboplatin and etoposide) for the initial treatment of extensive-stage small cell lung cancer (SCLC) marks the end of numerous failed attempts to improve survival for those with the deadly disease.

6-Feb-2019 4:05 PM EST
Study Finds HIV+ Cancer Patients Benefit From Immunotherapy
Georgetown Lombardi Comprehensive Cancer Center

The immunotherapy that has revolutionized treatment of many cancers appear to offer similar benefit to cancer patients living with HIV.

25-Oct-2018 5:00 AM EDT
Obese Mice Lose a Third of Their Fat Using a Natural Protein
Georgetown Lombardi Comprehensive Cancer Center

To the great surprise of cancer researchers in a Georgetown University-led study, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.

Released: 18-Sep-2018 12:00 PM EDT
Use of Electrical Brain Stimulation to Foster Creativity Has Sweeping Implications
Georgetown Lombardi Comprehensive Cancer Center

In an article published in Creativity Research Journal, Georgetown researchers address neuro-ethical concerns associated with the increasing use of transcranial electrical stimulation (tES).

15-Aug-2018 6:00 AM EDT
Georgetown Breast Cancer Advocates Make Their Case in Cancer Research Journal
Georgetown Lombardi Comprehensive Cancer Center

Georgetown Breast Cancer Advocates (GBCA), a volunteer group of survivors and other advocates who support and promote cancer research at Georgetown University, have published an article that underscores ways in which both the scientific and advocacy communities can foster a mutually beneficial collaboration.

10-Aug-2018 6:00 AM EDT
Large Collection of Brain Cancer Data Now Easily, Freely Accessible to Global Researchers
Georgetown Lombardi Comprehensive Cancer Center

A valuable cache of brain cancer biomedical data, one of only two such large collections in the country, has been made freely available worldwide by researchers at Georgetown Lombardi Comprehensive Cancer Center.

Released: 4-Apr-2018 7:05 AM EDT
Georgetown University Medical Center Selected as Lewy Body Dementia Research Center of Excellence
Georgetown Lombardi Comprehensive Cancer Center

The Lewy Body Dementia Association has designated Georgetown University Medical Center as a “Research Center of Excellence.”

Released: 21-Mar-2018 9:05 AM EDT
Georgetown Among First Universities to Collaborate with the Coalition for Epidemic Preparedness Innovations U.S.
Georgetown Lombardi Comprehensive Cancer Center

Georgetown University and CEPI U.S. – the Coalition for Epidemic Preparedness Innovations U.S. – today announce a new agreement to explore joint cooperative academic and research initiatives.

8-Feb-2018 12:45 PM EST
Family History Increases Breast Cancer Risk Even in Older Women: Weighing Screening Options
Georgetown Lombardi Comprehensive Cancer Center

Family history of breast cancer continues to significantly increase chances of developing invasive breast tumors in aging women — those ages 65 and older, according to research published in JAMA Internal Medicine. The findings could impact mammography screening decisions later in life.

8-Feb-2018 7:05 AM EST
New Immunotherapy Combination Tolerable, Effective in Patients with Advanced Kidney Cancer
Georgetown Lombardi Comprehensive Cancer Center

Combining an anti-angiogenesis agent, which blocks blood vessel formation, with an immunotherapy agent, was found to have promising anti-tumor activity and no unexpected side effects in an early-phase clinical trial in patients with advanced kidney cancer.

26-Jan-2018 11:05 AM EST
Unique Research Approach Finds FDA Approved Drug Shuts Down Ewing Sarcoma Cells in Lab
Georgetown Lombardi Comprehensive Cancer Center

Based on a novel approach to drug discovery, researchers at Georgetown Lombardi Comprehensive Cancer Center say an agent approved to treat a type of leukemia might also help young people with a much rarer and aggressive form of cancer, Ewing sarcoma.

25-Jan-2018 11:05 AM EST
Language Is Learned in Brain Circuits That Predate Humans
Georgetown Lombardi Comprehensive Cancer Center

It has often been claimed that humans learn language using brain components that are specifically dedicated to this purpose. Now, new evidence strongly suggests that language is in fact learned in brain systems that are also used for many other purposes and even pre-existed humans, say researchers.

Newswise: Researchers Offer New Model for Uncovering True HIV Mortality Rates in Zambia
11-Jan-2018 12:05 PM EST
Researchers Offer New Model for Uncovering True HIV Mortality Rates in Zambia
Georgetown Lombardi Comprehensive Cancer Center

A new study that seeks to better ascertain HIV mortality rates in Zambia could provide a model for improved national and regional surveillance approaches, and ultimately, more effective HIV treatment strategies.

4-Jan-2018 5:05 AM EST
Gene Test to Predict Breast Cancer Recurrence Less Cost Effective in Real World Practice
Georgetown Lombardi Comprehensive Cancer Center

The most commonly used gene expression profile test, Oncotype DX®, used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers.

Newswise: Soy, Cruciferous Vegetables Associated with Fewer Common Side Effects of Breast Cancer Treatment
8-Dec-2017 12:05 PM EST
Soy, Cruciferous Vegetables Associated with Fewer Common Side Effects of Breast Cancer Treatment
Georgetown Lombardi Comprehensive Cancer Center

Consuming soy foods (such as soy milk, tofu and edamame) and cruciferous vegetables (such as cabbages, kale, collard greens, bok choy, Brussels sprouts, and broccoli) may be associated with a reduction in common side effects of breast cancer treatment in breast cancer survivors, say a team of scientists.

30-Nov-2017 7:05 AM EST
New Test Provides Accurate Measure of DNA Damage from Chemical Compounds
Georgetown Lombardi Comprehensive Cancer Center

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

Newswise: Indoor Tanning Dependency Common in Young Women, Especially In Those With Depression
17-Oct-2017 12:05 AM EDT
Indoor Tanning Dependency Common in Young Women, Especially In Those With Depression
Georgetown Lombardi Comprehensive Cancer Center

A survey of young, white women who have used indoor tanning at least once in the past year showed that more than one in five of them have signs of being addicted to the high dose of ultraviolet (UV) radiation from tanning beds. In addition, women with symptoms of depression were three times more likely to meet the criteria for having a tanning dependence.

Newswise: Global Health Leader Mark Dybul Elected to National Academy of Medicine
Released: 16-Oct-2017 10:05 AM EDT
Global Health Leader Mark Dybul Elected to National Academy of Medicine
Georgetown Lombardi Comprehensive Cancer Center

The National Academy of Medicine announced today the election of Mark Dybul, MD, professor of medicine at Georgetown University School of Medicine, as one of its newest member. Dybul is faculty co-director of the Center for Global Health and Quality at Georgetown University Medical Center.

Newswise: NY State Medicaid Expansion Widened Racial Gap in Access to High-Quality Cancer Surgery
1-Oct-2017 12:05 PM EDT
NY State Medicaid Expansion Widened Racial Gap in Access to High-Quality Cancer Surgery
Georgetown Lombardi Comprehensive Cancer Center

The 2001 New York State Medicaid expansion — what is considered a precursor to the Affordable Care (ACA) — widened the racial disparity gap when it came to access to high-quality hospitals for cancer surgery, according to a new study from Georgetown University.

1-Oct-2017 7:05 PM EDT
Two Agents Deliver Knockout Punches to Ewing Sarcoma
Georgetown Lombardi Comprehensive Cancer Center

When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress.

28-Sep-2017 6:05 AM EDT
Tobacco Smokers Could Gain 86 Million Years of Life if they Switch to Vaping, Study Finds
Georgetown Lombardi Comprehensive Cancer Center

Up to 6.6 million cigarette smokers will live substantially longer if cigarette smoking is replaced by vaping over a ten-year period, calculates a research team led by investigators from Georgetown Lombardi Comprehensive Cancer Center. In all, cigarette smokers who switch to e-cigarettes could live 86.7 million more years with policies that encourage cigarette smokers to switch completely to e-cigarettes.

Released: 12-Sep-2017 5:05 AM EDT
Georgetown Hosts Global Health Security Expert Beth Cameron
Georgetown Lombardi Comprehensive Cancer Center

Beth Cameron, senior director for the Nuclear Threat Initiative’s Global Biological Policy and Programs, will discuss why U.S. leadership continues to be vital in advancing the Global Health Security Agenda’s mission to build a world safe from biological threats on Friday, Sept. 15 at Georgetown University,

Newswise: E-Cigarettes Can Help Smokers Quit, But There’s a Catch
25-Aug-2017 2:05 AM EDT
E-Cigarettes Can Help Smokers Quit, But There’s a Catch
Georgetown Lombardi Comprehensive Cancer Center

Frequent e-cigarette use does help smokers quit — a finding that researchers say supports the use of e-cigarettes as a cessation aid for those trying to quit cigarette smoking. But, they note, an examination of a recent national survey uncovers important clues about who’s successful at quitting and why.

Released: 3-Jul-2017 10:05 AM EDT
Animal Study Finds High-Fat Diet in Pregnancy Increases Breast Cancer Risk Over Generations
Georgetown Lombardi Comprehensive Cancer Center

Feeding pregnant female mice a diet high in fat derived from common corn oil resulted in genetic changes that substantially increased breast cancer susceptibility in three generations of female offspring, reports a team of researchers led by scientists at Georgetown Lombardi Comprehensive Cancer Center.

26-Jun-2017 2:20 PM EDT
Subtle Molecular Changes Along the Upper Digestive Tract Could Guide Cancer Therapy
Georgetown Lombardi Comprehensive Cancer Center

Based on a new molecular study of tissues biopsied from various parts of the upper digestive tract, researchers at Georgetown Lombardi Comprehensive Cancer Center have identified significant, if subtle, differences in gene mutations and other factors that could help in developing more tailored treatment options for cancer patients.

Newswise: Immunotherapy Brings New Hope to Patients with Advanced Melanoma
Released: 26-Jun-2017 11:55 AM EDT
Immunotherapy Brings New Hope to Patients with Advanced Melanoma
Georgetown Lombardi Comprehensive Cancer Center

Until recently, melanomas that had spread to the brain could only be treated with surgery and radiation therapy. And even with treatment, patients typically lived only a median of four months. However, patients like Kathy Roberts now have alternatives. After having surgery to repair the damage from the tumors in her ankle, her doctors encouraged her to enroll in a clinical trial of immunotherapy for patients with melanoma brain tumors at Georgetown Lombardi Comprehensive Cancer Center, which she did.

14-May-2017 4:00 PM EDT
Deficiencies in Repair of DNA Identified in Many Types of Solid Tumors
Georgetown Lombardi Comprehensive Cancer Center

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

14-May-2017 4:00 PM EDT
A Counterintuitive Finding That Could Benefit Younger Colorectal Cancer Patients
Georgetown Lombardi Comprehensive Cancer Center

Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

14-May-2017 5:00 PM EDT
Number of Mutations in a Tumor Varies by Age and Type of Cancer
Georgetown Lombardi Comprehensive Cancer Center

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient’s cancer biopsy varied by age and the type of cancer, along with several other factors.

Newswise: Smoking Cessation Counseling Successful When Paired with Lung Cancer Screening
8-Feb-2017 2:05 PM EST
Smoking Cessation Counseling Successful When Paired with Lung Cancer Screening
Georgetown Lombardi Comprehensive Cancer Center

The first successful randomized trial of its kind provides preliminary evidence that telephone-based smoking cessation counseling given to smokers shortly after undergoing lung cancer screening can be effective at helping people stop smoking.

26-Jan-2017 6:05 AM EST
Understanding When Eating Soy Might Help or Harm in Breast Cancer Treatment
Georgetown Lombardi Comprehensive Cancer Center

Georgetown Lombardi Comprehensive Cancer Center researchers have used animal models to reveal new information about the impact – positive and negative – that soy consumption could have on a common breast cancer treatment.


Showing results

150 of 94

close
0.23958