As AI is deployed in clinical centers across the U.S., one important consideration is to assure that models are fair and perform equally across patient groups and populations. To better understand the fairness of medical imaging AI, a team of researchers trained over 3,000 models spanning multiple model configurations, algorithms, and clinical tasks.
Cancer cells frequently overhaul their surroundings, making tumors stiffer than nearby healthy tissue. While tumor stiffening makes some cancers easier to detect — this is why physicians feel for hard lumps in the body — it can also ramp up tumor growth and drug resistance. New research suggests that these detrimental changes are not set in stone, however.
A lumbar puncture, also known as a spinal tap, can be challenging for physicians to perform manually. A new ultrasound navigation system could provide accurate, real-time, and intuitive needle insertion planning and guidance.
Blueprint MedTech is a National Institutes of Health (NIH) technology incubator program that is part of the NIH Blueprint for Neuroscience Research and for the past two years has provided funding and expertise to fast-track the development of therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems.
A pilot study shows that a new wearable lung sensor combined with deep learning can automatically detect wheezes, a common indicator of asthma and COPD
Physical human feats require a high level of coordination between the sensory functions of our skin and motor functions of our muscles. What kind of achievements could robots perform with the same cohesion between sensing and action? In the medical space, researchers have begun to explore the possibilities.
Now in its 13th year, the annual DEBUT Challenge calls on teams of undergraduate students to identify healthcare problems and develop technological solutions. NIH and VentureWell selected 11 winners and five honorable mentions and will award prizes totaling $160,000.
A team of NIBIB-funded researchers recently developed an AI platform that can analyze 3D pathology images to predict disease outcomes. Their method had improved performance in predicting prostate cancer outcomes when compared with traditional pathology approaches, such as analysis by expert pathologists using 2D images.
Because of its high accuracy, laboratory-based polymerase chain reaction (PCR) testing is the gold standard for infectious disease diagnostics. Yet PCR requires highly trained staff and costly equipment, hindering its availability, especially in low-resource settings. New research suggests a different kind of test could be more streamlined without sacrificing performance.
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body, reducing the burden on patients who require frequent drug administrations.
NIBIB-funded researchers are working to make bladder surgeries better, tackling the issue from two vantage points: improving bladder function using a biodegradable construct that facilitates tissue regeneration, and enhancing patient monitoring by developing an implantable bladder sensor.
To date, nine medical device developers participating in the RADx® Tech Independent Test Assessment Program have received emergency use authorization for at-home and point-of care test products that simultaneously detect COVID-19 and flu A/B.
Wounds that are superficial for some can be life-threatening for others. With diabetic wounds, healing can be slow, particularly in the feet, increasing the tissue’s susceptibility to infection. Foot ulcers and other diabetic foot complications have similar mortality rates to some cancers, yet progress toward improved treatments has plateaued.
A team of scientists at the Massachusetts Institute of Technology (MIT), Brigham and Women’s Hospital, and Harvard University have developed a noninvasive alternative—an oral capsule containing a tiny vibrating motor that is designed to stimulate the stomach to produce the same sense of fullness people experience after eating a large meal.
A collaborative NIH-funded team is using AI to mine common chest CT scans to predict mortality. Their research identified a collection of cardiac factors that were predictive of death in a large group of patients, potentially setting the stage for improved cardiac screening.
Measuring heart rate or body temperature may sound easy, but retrieving the data from small animals with bulky traditional tech is difficult, especially during behavioral tests, which are critical for understanding brain disorders. Thanks to a recent study, the animal data is now in reach.
How a non-invasive technique temporarily opened the blood-brain barrier to deliver an immunotherapy drug to the brain in a large animal study.
NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a signal using an optical imaging technique known as Raman spectroscopy.
To mark the 10-year anniversary of the NIBIB-led Concept to Clinic: Commercializing Innovation (C3i) program, we feature three innovators who participated in the program at the early stages of their biomedical technologies.
While pacemakers have been instrumental in treating many patients with heart rhythm disorders, their bulky design and dependence on wires can limit their usefulness and poses a risk of heart damage or infection. Researchers have cut the cords, shrunk the size, and expanded the capabilities of current designs.
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