Latest News from: University of California San Diego Health

Add to Favorites Subscribe Share
Go to Advanced Search

Showing results

110 of 1417
MHC-II_UCSDHealth.png

Article ID: 700863

Cancer Immunotherapy Might Benefit From Previously Overlooked Immune Players

University of California San Diego Health

Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell’s binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.

Released:
20-Sep-2018 1:05 PM EDT
endo_cells_GPCR_and_E3_ligase.jpg

Article ID: 700730

How Cells Repurpose their Garbage Disposal Systems to Promote Inflammation

University of California San Diego Health

Researchers at University of California San Diego School of Medicine have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.

Released:
18-Sep-2018 1:05 PM EDT
cannabis_2_leaf_pixabay.jpg

Article ID: 700703

Study to Examine Possible Effects of Cannabis Compound for Common Movement Disorder

University of California San Diego Health

Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor (ET). Currently, ET is treated using repurposed medications originally developed for high blood pressure or seizures.

Released:
18-Sep-2018 10:05 AM EDT
UCHealthHack_2018.jpg

Article ID: 700650

When it Comes to Health Care, Can You Hack It?

University of California San Diego Health

On Saturday, October 6, hundreds of hackers are expected to descend upon the University of California San Diego campus to put their collaborative problem-solving capabilities to the test.

Released:
17-Sep-2018 12:05 PM EDT
nfowleri_tamoxifen_epiminolanosterol_UCSDHealth.jpg
  • Embargo expired:
    13-Sep-2018 2:00 PM EDT

Article ID: 700346

Cancer Drug and Antidepressants Provide Clues for Treating Fatal Brain-Eating Amoeba Infections

University of California San Diego Health

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.

Released:
11-Sep-2018 2:05 PM EDT
sirius_red_casp2_karin.jpg
  • Embargo expired:
    13-Sep-2018 11:00 AM EDT

Article ID: 700321

Caspase-2 Enzyme Inhibition Shows Promise for Ameliorating Fatty Liver Disease

University of California San Diego Health

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.

Released:
11-Sep-2018 11:05 AM EDT
spencer_eli.png

Article ID: 700402

Researchers Develop Biometric Tool for Newborn Fingerprinting

University of California San Diego Health

Researchers at the University of California San Diego say they have dramatically advanced the science of biometric identification, creating a novel technology that can capture the fingerprints of infants and children, even on the first day of birth.

Released:
12-Sep-2018 11:05 AM EDT
runners_pixabay.jpg
  • Embargo expired:
    11-Sep-2018 7:05 PM EDT

Article ID: 700062

A Single Gene Mutation May Have Helped Humans Become Optimal Long-Distance Runners

University of California San Diego Health

Two to three million years ago, the functional loss of a single gene triggered a series of changes in what would eventually become the modern human species. Researchers at University of California San Diego School of Medicine report on studies of mice engineered to lack the same gene and resulting data that suggest the lost gene may also have contributed to humanity’s well-documented claim to be among the best long-distance runners in the animal kingdom.

Released:
5-Sep-2018 4:30 PM EDT
carlin_human_macrophages_zika.jpg

Article ID: 700275

Zika Virus Strips Immune Cells of Their Identity

University of California San Diego Health

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.

Released:
10-Sep-2018 3:05 PM EDT
mitocondrion_deerinck_tem_horiz.jpg

Article ID: 700214

Chronic Diseases Driven by Metabolic Dysfunction

University of California San Diego Health

Progress in treating chronic illness, where the cause of the problem is often unknown, has lagged. Chronic conditions like cancer, diabetes and cardiovascular disease defy easy explanation, let alone remedy. In a new paper, a researcher at University of California San Diego School of Medicine, posits that chronic disease is essentially the consequence of the natural healing cycle becoming blocked, specifically by disruptions at the metabolic and cellular levels.

Released:
7-Sep-2018 2:05 PM EDT

Showing results

110 of 1417

Chat now!