Mass General Brigham study reveals that ED visits and death are heightened weeks after major climate-driven extreme weather events – highlighting the long-lasting impacts these events may have on health and infrastructure
Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have different microenvironments.
In a meta-analysis of 5,000 participants, including more than 500 who underwent in-person assessments over two years, multivitamins showed benefits for memory and global cognition.
Mass General Brigham researchers report that women who experienced more stress before conception had higher blood sugar levels during pregnancy, apredictor of current and long-term cardiovascular health.
Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients—and it comes with bristles on one end.
Large language models (LLMs) like ChatGPT and GPT-4 have the potential to assist in clinical practice to automate administrative tasks, draft clinical notes, communicate with patients, and even support clinical decision making.
A new study highlights how stigmatizing attitudes about individuals with acne may influence social and professional perceptions.
The surgery did not improve the children’s neurodevelopmental functioning but was associated with improved quality of life, sleep symptoms, and blood pressure 12-months post-surgery according to a randomized control trial led by researchers at Brigham and Women’s Hospital and the Harvard Pilgrim Health Care Institute
Microbial communities are thought to contain keystone species, which can disproportionately affect the stability of the communities, even if only present in low abundances. Identifying these keystone species can be challenging, especially in the human gut, since it is not feasible to isolate them through systematic elimination.
Research consortium investigators analyzed over 314,000 cells from rheumatoid arthritis tissue, defining six types of inflammation involving diverse cell types and disease pathways
Bronchiectasis, a condition defined by widened lung airways, cough and sputum production, and frequent infections, often presents along with chronic obstructive pulmonary disease (COPD).
Using data from Mass General Brigham’s electronic health records, Brigham researchers quantified the burden of SARS-CoV-2-associated sepsis early in the pandemic
Gentrification can have a ripple effect on communities. While it can improve certain conditions in typically low-income areas, rising housing costs can displace residents, causing social disruption and other downstream effects.
Researchers are gaining new insights into neurological diseases by studying circular RNAs (circRNAs) in brain cells.
A study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury and those without TBI.
It’s estimated that around 25% of patients who have a cardiac arrest and receive cardiopulmonary resuscitation (CPR) in a normal hospital setting will survive.
A study led by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, reveals multiple associations between the presence of phenol biomarkers and altered thyroid hormone measurements among women seeking fertility care.
Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome are debilitating conditions with similar symptoms. Neither condition has diagnostic tests or treatments approved by the Food and Drug Administration (FDA) and each cost the United States billions of dollars each year in direct medical expenses and lost productivity.
Over 37 million Americans have diabetes, and 90-95% of that population are diagnosed with type 2 diabetes. Lifestyle interventions, such as a healthy diet and a regular physical activity program, are methods to manage diabetes.
A new study led by researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, has found that mucus plugs were also associated with greater mortality.
Through data-analysis, researchers found that people taking long siestas had higher body mass indexes and were more likely to have metabolic syndrome than those who did not take siestas.
Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit. A new study led by researchers at Brigham and Women’s Hospital, a founding member of Mass General Brigham, used public Medicare data to identify the 50 highest-selling brand-name drugs in 2020.
The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.
Burnout is associated with adverse outcomes including medical errors and lower quality of care. While many studies have focused on physician or nurse burnout, the COVID-19 pandemic increased stress across the healthcare workforce, including support staff and healthcare teams who have a crucial role in patient care.
The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.
A pilot trial by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.
To evaluate best strategies for increasing vaccination rates, researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, collaborated with Danish researchers to develop and implement a nationwide trial in Denmark testing nine different electronic messaging tactics among adults over age 65.
Heart disease is the leading cause of death worldwide, killing someone in the United States every 34 seconds, according to the Centers for Disease Control and Prevention. A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, conducted the first population-based study on patients’ nonacceptance of statin therapy recommendations.
Occupational factors, such as physical demands and work schedules, were associated with higher sperm concentrations and serum testosterone among men in the EARTH study.
Strokes are a leading cause of morbidity and mortality in the United States, as well as around the world. Various environmental and biological factors are known to affect the risks and outcomes of strokes.
Women are disproportionately affected by migraine, especially during their reproductive years.
Pulmonary arterial hypertension (PAH) is a rare and incurable disease of the lung arteries that causes early death.
Two major health conditions appear to share a connection. Multiple sclerosis (MS), a disease which eats away at the body’s central nervous system, affects millions of people globally and depression, a mood disorder with debilitating symptoms, affects hundreds of millions of people globally.
Of the nearly 4 million births each year in the United States, roughly 50,000 are marked by life-threatening complications, and up to 900 result in maternal death during delivery.
Pain in the back or the neck is extremely common and accounts for more healthcare spending than any other health condition.
With modern therapies for heart failure (HF) with reduced ejection fraction (HFrEF), some patients can improve their cardiac function during treatment.
Alzheimer’s disease (AD) is the fifth leading cause of death in adults over 65 years old. While many potential treatments for the neurodegenerative disease focus on developing drugs to target key culprits, a relatively new approach aims to more directly treat the brain.
In early 2020, before COVID-19 vaccines and effective treatments were widely available, universal mask wearing was a central strategy for preventing the transmission of COVID-19. But hospitals and other settings with mask mandates faced a challenge.
People with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate 50 percent increase in risk of CV events such as heart attack and stroke.
Since March 2020, COVID-19-related deaths claimed over a million lives in the U.S. alone.
A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, demonstrated that shingles, also known as herpes zoster, is associated with an almost 30% higher long-term risk of a major cardiovascular event such a stroke or heart attack.
Alzheimer’s Dementia and Related Disorders (ADRD) affects upwards of 5 million people in the United States, with no known treatments to stop or prevent its progression.
When it comes to heart failure (HF), sex differences are known to impact everything from risk factors to clinical presentation to response to treatment, making sex a key factor to consider in studies of emerging pharmacotherapies.
Lipoprotein(a) is a special type of bad cholesterol that is believed to contribute to heart disease, but there are no approved pharmacological therapies to decrease its concentration in the bloodstream.
Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases.
Today, patients utilizing their Medicare Hospice Benefits with end-stage kidney disease (ESKD) are forced to make the traumatic choice between continuing dialysis or enrolling in hospice.
In the United States, the electronic health record (EHR) has become increasingly prevalent in the day-to-day practice of physicians, with primary care physicians (PCPs) spending the most time in the EHR.
Alzheimer’s disease (AD) currently has no cure and is predicted to affect over 100 million people worldwide by 2050. Ongoing research is focused on two key neurotoxic proteins: amyloid beta (Aβ) and tau.
Survivors of traumatic injury often face many long-term health consequences including physical disabilities, mental illness and issues with social integration.
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