New Cleveland Clinic-led research provides evidence that video laryngoscopy significantly decreased the number of attempts needed to achieve intubation in adult surgical patients who required single-lumen endotracheal intubation for general anesthesia, compared with direct laryngoscopy. The research was published today in JAMA.
CLEVELAND, OH and TITUSVILLE, FL: Cleveland Clinic and Parrish Medical Center, a Parrish Healthcare integrated care partner, jointly announced that Parrish Medical Center has become a member of Cleveland Clinic Connected.
New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients.
Sildenafil is the main component of drugs used to treat erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio).
Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi’s sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.
Research by Cleveland Clinic and three other U.S. medical centers has found that bariatric surgery provides better long-term control of blood glucose levels in patients with obesity and type 2 diabetes, compared with medical therapy.
David Liska, M.D., a colorectal surgeon and director of Cleveland Clinic's Center for Young-Onset Colorectal Cancer, explains that multiple factors are contributing to the uptick in young-onset colorectal cancer cases.
Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.
New Cleveland Clinic research has mapped changes in tumor-related bacteria to uncover potential new strategies to combat the rise of young-onset colorectal cancer (CRC) in people under the age of 50.
Researchers from Cleveland Clinic and IBM have published a strategy for identifying new targets for immunotherapy through artificial intelligence (AI).
Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly. The results highlight a potential new strategy for developing targeted treatments for triple-negative breast cancer, which currently has no approved options.
Targeted drugs attack cancer cell functions directly, offering a more precise approach to complement broader treatments like chemotherapy. A research team led by Ofer Reizes, PhD, and Justin Lathia, PhD, designed a peptide therapeutic that disrupts the molecular processes behind aggressive cancer growth when delivered into cells.
The drug stopped cancer growth and induced tumor cell death, and only affected cancerous cells in preclinical work. The study was highlighted in the January issue of Molecular Cancer Therapeutics.
Hani Najm, M.D., Cleveland Clinic Children’s Chair of Pediatric and Congenital Heart Surgery, has been named the first winner of the Great Arab Minds award in medicine in recognition of his outstanding contributions to pediatric and adult cardiac surgery, including his innovations to surgically treat congenital heart diseases.
A Cleveland Clinic study looked at the long-term use of anti-obesity medications and found that only 19% of the study participants continued to use the medications one year after their initial prescriptions.
November 27, 2023: Cleveland Clinic and Canon Inc. have announced intentions to form a strategic research partnership to develop innovative imaging and healthcare IT technologies aimed at improving diagnosis, care and outcomes for patients.
Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer’s and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women’s increased risk for the disease and its severity.
Cleveland Clinic is the first medical center in the United States to have performed a minimally invasive gastric sleeve procedure using a recently FDA-approved surgery robot with magnetic technology.
New Cleveland Clinic research reveals how BRCA1 and BRCA2 gene mutations may impact cell communication in breast tissue, furthering the understanding of how cancer develops.
The findings, published in Molecular Cancer Research, provide a foundation for personalized approaches to prevent and treat breast cancer based on a patient's genetics. The discovery paves the road for future studies of the process where normal cells become cancerous in BRCA1- and BRCA2-deficient breast tissue.
Cleveland Clinic has launched the Cleveland Clinic Quantum Innovation Catalyzer Program, a competitive program for start-up companies to explore quantum computing applications in healthcare and life sciences.
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Findings from a trial led by Cleveland Clinic show that patients with atrial fibrillation undergoing a transcatheter aortic valve replacement (TAVR) at the same time as a left atrial appendage occlusion (LAAO) procedure using the Watchman™ device had similar outcomes when compared to patients getting TAVR in addition to medical therapy or blood thinners.
The Arthritis Foundation has named Cleveland Clinic as the future home for its Osteoarthritis Imaging Center (OIC), designed to become the largest repository in the country for imaging data from post-traumatic osteoarthritis clinical trials and therapies.
More and more, people are using the internet and online platforms to research health conditions, and it is vital users have access to accurate, quality information on these platforms. To kick-off World Mental Health Day on October 10th, Cleveland Clinic has teamed up with TikTok to help users find educational and accurate mental health content.
Tuesday, October 10, 2023, CLEVELAND: Cleveland Clinic and RedSalud – a private healthcare network in Chile – have formed a joint advisory council with the goal of providing strategic and transparent leadership guidance in the areas of operations, growth and patient experience.
Timothy Chan, M.D., Ph.D., chair of Cleveland Clinic's Global Center for Immunotherapy and Precision Immuno-Oncology and Sheikha Fatima Bint Mubarak Endowed Chair in Immunotherapy and Precision Immuno-Oncology, has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.
CLEVELAND: A team from Cleveland Clinic has developed a new model for prioritizing patients waiting for a lung transplant, aimed at improving outcomes and reducing deaths among those in need of donor lungs. The new method offers an improved strategy for organ allocation by taking into account how the time a patient has spent on the waiting list could impact the severity of their disease and the urgency of their need for a transplant.
The results of a study looking at this new method were published today in The American Journal of Respiratory and Critical Care Medicine.
New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with Omicron subvariants.
Cleveland Clinic’s 8th annual MENtion It educational campaign examined various aspects of men’s health including physical activity levels, sexual health, mental well-being, and cancer screening practices.
Cleveland Clinic London is the first hospital in London to successfully perform a total knee replacement procedure with the assistance of an augmented reality-based surgical platform that was designed with artificial intelligence and machine learning.
A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.
Cleveland Clinic researchers have found that starting peanut oral immunotherapy under medical supervision during infancy can improve a child’s immune response to the food over time. The findings were recently published in the Journal of Allergy & Clinical Immunology: In Practice.
A multidisciplinary team of 25 Cleveland Clinic Sports Medicine physicians, athletic trainers, physical therapists and primary care staff will be traveling with the clubs and providing care for the teams during training, matches and after matches.
Researchers presenting preliminary data from a clinical trial aimed at discovering a cure for sickle cell disease reveal positive results among its first patients. Sickle cell disease, a genetic blood disorder, is a painful and debilitating condition for which there are few approved therapies.
New research from Cleveland Clinic supports the theory that environmental exposures – such as red meat consumption and sugar intake – may play a role in the rising incidence of young-onset colorectal cancer.
Researchers found that people younger than age 50 with colorectal cancer had lower levels of citrate, which is created in the process of converting food into energy, compared to older people diagnosed with colorectal cancer.
In honor of Mother’s Day, American Greetings and the Women’s Alzheimer’s Movement at Cleveland Clinic have partnered to encourage the celebration of women everywhere and raise critical research funds in the process.
Cleveland Clinic has been designated a Rare Disease Center of Excellence by the National Organization for Rare Disorders (NORD). The new Cleveland Clinic Center for Rare Diseases is one of 40 U.S. academic medical centers selected to join the first-of-it-kind national network dedicated to diagnosing, treating and researching all rare diseases.
Findings from a Cleveland Clinic-led study showed for patients with community-acquired pneumonia treated with intravenous (IV) antibiotics, earlier switching to oral antibiotics in clinically stable patients was associated with shorter duration of antibiotics and hospital stay.
A Cleveland Clinic landmark study on obesity and cancer, led by Ali Aminian, M.D., director of Cleveland Clinic’s Bariatric & Metabolic Institute, was recognized with a 2023 Top Ten Clinical Research Achievement Award by the Clinical Research Forum (CR Forum). The award-winning paper, the SPLENDID study that was published in JAMA, also received an additional recognition as a Distinguished Clinical Research Awardee.
Cleveland Clinic researchers found 41% of patients with long COVID, had moderate to severe sleep disturbances. The retrospective analysis also identified risk factors for moderate to severe sleep disturbances, including race, hospitalization for COVID-19, greater anxiety severity and fatigue. After adjusting for demographics, Black patients were three times more likely to develop these sleep disturbances. The findings were published in Journal of General Internal Medicine.
Cleveland Clinic has opened a new state-of-the-art cancer facility, named the Fatima bint Mubarak Center, at Cleveland Clinic Abu Dhabi, located in the United Arab Emirates capital.
Cleveland Clinic has received a transformational philanthropic gift from the United Arab Emirates, in the name of H.H. Sheikha Fatima bint Mubarak, that will support global pathogen and cancer research.