Latest News from: University of Alabama at Birmingham

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Released: 28-Feb-2024 10:05 PM EST
New study finds high-dose inhaled nitric oxide decreases the risk of death among critically ill Black patients with COVID-19
University of Alabama at Birmingham

In a first-of-its-kind study published in the American Journal of Respiratory and Critical Care Medicine, physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine discovered that high-dose inhaled nitric oxide therapy may improve oxygenation and reduce the risk of mortality among critically ill Black patients with COVID-19.

Newswise: An enhanced brain delivery of antibodies heightens the potential to treat brain diseases
Released: 4-Jan-2024 5:05 AM EST
An enhanced brain delivery of antibodies heightens the potential to treat brain diseases
University of Alabama at Birmingham

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

Newswise: Type 1 diabetes: B cell-derived natural antibodies suppress autoimmune pathogenesis
Released: 6-Dec-2023 5:05 AM EST
Type 1 diabetes: B cell-derived natural antibodies suppress autoimmune pathogenesis
University of Alabama at Birmingham

Researchers have discovered the novel mechanism that underlies a previously reported observation that infection by group A Streptococcus bacteria reduces the risk of later developing Type 1 diabetes.

Released: 8-May-2023 12:25 PM EDT
How interleukin-6 helps prevent allergic asthma and atopy by suppressing interleukin-2 signaling
University of Alabama at Birmingham

The immune system has a biological telecommunications system — small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

Released: 22-Mar-2023 5:20 PM EDT
Memory B cell marker predicts long-lived antibody response to flu vaccine
University of Alabama at Birmingham

In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

Released: 7-Mar-2023 4:20 PM EST
FDA mandate to limit acetaminophen in acetaminophen-opioid medications is associated with reduced serious liver injury
University of Alabama at Birmingham

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury.

Released: 16-Aug-2022 4:05 PM EDT
New understanding of how faulty metabolism triggers adrenal cancer
University of Alabama at Birmingham

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands.

Newswise: Testing a promising treatment for functional seizures in children
Released: 21-Dec-2021 5:05 PM EST
Testing a promising treatment for functional seizures in children
University of Alabama at Birmingham

Clinical psychologist Aaron Fobian, Ph.D., has developed a therapy for this debilitating condition that she is now testing in a major NIH-sponsored clinical trial.

Released: 17-Dec-2021 11:05 AM EST
New gene therapy could provide cure for sickle cell disease, according to UAB study
University of Alabama at Birmingham

Although unproven, this novel sickle cell therapy serves as a potential cure. More measures need to be taken to determine long-term function and organ improvement.

Released: 22-Nov-2021 5:55 PM EST
Superheroes: Helping or hurting children?
University of Alabama at Birmingham

Could superheroes make children participate in more dangerous play time? A UAB graduate research assistant is conducting a study to see whether superheroes could be related to adolescent injuries.

Newswise: The science behind cooking a delicious Thanksgiving meal
Released: 19-Nov-2021 10:15 AM EST
The science behind cooking a delicious Thanksgiving meal
University of Alabama at Birmingham

Lizzy Davis with the UAB Department of Nutrition Sciences shares the science of how to make your Thanksgiving worth gobbling up. “Many people think that they don’t have the skills to be a good cook, but cooking is science,” Davis said.

Released: 29-Oct-2021 11:40 AM EDT
Making the case to improve outcomes for sickle cell disease
University of Alabama at Birmingham

UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.

Released: 27-Oct-2021 2:45 PM EDT
New research shows most people are honest — except for a few
University of Alabama at Birmingham

About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.

Released: 6-Oct-2021 2:50 PM EDT
Learning magic tricks can help self-esteem of kids with ADHD
University of Alabama at Birmingham

The study, from UAB’s Institute for Arts in Medicine, shows that learning tricks in a magic camp can boost feelings of self-esteem and confidence in children and adolescents with disabilities.

Released: 30-Sep-2021 2:40 PM EDT
Differentiating between COVID-19 and chronic rhinosinusitis
University of Alabama at Birmingham

UAB’s Jessica Grayson, M.D., clears the confusion on how to tell COVID-19 from other respiratory illnesses.

Newswise: $100 million in gifts to transform UAB School of Medicine
Released: 29-Sep-2021 8:25 AM EDT
$100 million in gifts to transform UAB School of Medicine
University of Alabama at Birmingham

In grateful recognition of a transformational $95 million lead gift from longtime University of Alabama at Birmingham supporter Marnix E. Heersink, M.D., the UAB School of Medicine will now be named the UAB Marnix E. Heersink School of Medicine.

Released: 23-Sep-2021 2:05 PM EDT
COVID-19 vaccines and men’s reproductive health
University of Alabama at Birmingham

UAB’s Adam Baumgarten, M.D., shares more on the safety of the COVID-19 vaccine for men.

Released: 5-Sep-2021 7:05 PM EDT
Seven universities adopt Okanagan Charter, join UAB in U.S. Health Promoting Campus Network
University of Alabama at Birmingham

Health Promoting Universities are an international community that aspires to transform the health and sustainability of current and future societies, strengthen communities, and contribute to the well-being of people, places and the planet.

Newswise: Five common thinking traps and how to avoid them
Released: 31-Aug-2021 8:15 AM EDT
Five common thinking traps and how to avoid them
University of Alabama at Birmingham

UAB’s Megan Hays, Ph.D., shares how to overcome common negative thinking traps by using cognitive behavioral therapy.

Released: 27-Aug-2021 12:05 PM EDT
Mind over matter? Recognizing your hunger cues
University of Alabama at Birmingham

Two nutrition researchers at UAB claim that hunger cues go well beyond your stomach’s rumbling and grumbling — it has more to do with your overall mindfulness.

Released: 12-Jul-2021 1:05 PM EDT
Patient Trapped by Fallen Tree During Tornado Walks Again Thanks to UAB
University of Alabama at Birmingham

Arnoldo Vasquez Hernandez was pinned under an oak tree that fell on his house during a tornado in January 2021, requiring a rare, in-the-field amputation. After being fitted for a prosthetic leg, he is now able to take his first steps in nearly five months.

Released: 18-Jun-2021 3:10 PM EDT
Undiagnosed and Untreated Disease Identified in Rural South Africa
University of Alabama at Birmingham

A comprehensive health-screening program in rural northern KwaZulu-Natal, South Africa, has found a high burden of undiagnosed or poorly controlled non-communicable diseases, according to a study published in The Lancet Global Health.

Released: 18-Jun-2021 11:55 AM EDT
Will Reduction in Tau Protein Protect Against Parkinson’s and Lewy Body Dementias?
University of Alabama at Birmingham

A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.

Released: 15-Jun-2021 2:55 PM EDT
Data and Safety Review Board Reports How it Monitored the COVID-19 Vaccine Trials
University of Alabama at Birmingham

Evaluation of three vaccine candidates during the COVID-19 pandemic fell to 12 experts of the federally appointed COVID-19 Vaccine Data and Safety Monitoring Board. This team has now taken the unusual step of publishing details of their review process in The Journal of Infectious Diseases.

Released: 10-Jun-2021 4:45 PM EDT
How does COVID-19 affect patients with cancer? Largest U.S. study shares first results
University of Alabama at Birmingham

New findings include a significant increase in risk of death among patients who had recently had chemotherapy.

Released: 8-Jun-2021 12:05 PM EDT
A clear decision: cataract detection and removal
University of Alabama at Birmingham

For anyone experiencing changes in vision, a comprehensive eye exam is essential. However, because the changes related to cataracts can be slow and subtle, it is better not to wait until your sight is significantly affected.

Released: 27-May-2021 4:05 PM EDT
UAB’s new Immunology Institute provides new avenues for discovery
University of Alabama at Birmingham

UAB has established an interdisciplinary hub for research and patient care in the study of immunity.

Released: 25-May-2021 12:05 PM EDT
COVID-19 mRNA vaccines: How could anything developed this quickly be safe?
University of Alabama at Birmingham

For many, the arrival of COVID-19 mRNA vaccines in less than a year is, quite literally, unbelievable. That skepticism feeds hesitancy to take the vaccines. But development of mRNA vaccines against COVID-19 is no overnight success. In fact, they have a remarkable backstory stretching back decades.

Released: 21-May-2021 1:15 PM EDT
UAB’s American Chemical Society chapter honored for its work during COVID-19 pandemic
University of Alabama at Birmingham

The UAB undergraduate Student Affiliates group of the American Chemical Society has been awarded its highest recognition for the 2019-2020 academic year, Outstanding Student Chapter Award.

Released: 11-May-2021 2:50 PM EDT
Five benefits of getting a COVID-19 vaccine
University of Alabama at Birmingham

UAB experts explain some of the benefits of getting a COVID-19 vaccine.

Released: 11-May-2021 2:45 PM EDT
Physics courses inspired by ‘good games’ help draw high schoolers to STEM careers
University of Alabama at Birmingham

Coding with Physics workshops train teachers to incorporate storytelling, supportive teamwork, productive failure and other video game techniques to engage teens in science.

Released: 10-May-2021 5:10 PM EDT
Intranasal COVID-19 vaccine candidate shows sterilizing immunity in preclinical tests
University of Alabama at Birmingham

A single intranasal dose of a COVID-19 vaccine candidate created by Altimmune Inc. provides sterilizing immunity in the lungs of vaccinated animals. In contrast, non-vaccinated animals showed dense pulmonary infection and disease following infection with the virus that causes COVID-19.

Released: 28-Apr-2021 11:20 AM EDT
High consumption at night of branch chain amino acids — found in meats, eggs, fish and nuts — could negatively impact the heart
University of Alabama at Birmingham

A new study published in the Journal of Molecular and Cellular Cardiology by University of Alabama at Birmingham researchers shows that an increase in the consumption of branch chain amino acids later in the day could result in a negative effect on cardiovascular health.

Released: 26-Apr-2021 4:05 PM EDT
Study says inflammation seen in earliest stages of Parkinson’s disease, and it is different between men and women
University of Alabama at Birmingham

New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.

Released: 23-Mar-2021 4:25 PM EDT
Masking may help prevent severe allergies this spring
University of Alabama at Birmingham

Masking can prevent more than COVID-19 from spreading this spring: Allergic rhinitis symptoms have shown to be significantly reduced with facemask usage during the pandemic.

Released: 15-Mar-2021 5:20 PM EDT
Researchers identify potential therapeutic target against malignant brain tumors
University of Alabama at Birmingham

Researchers at UAB have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer. The findings indicate that an adhesive cell surface protein known as N-cad may be key in overcoming glioblastoma’s resistance to radiation therapy.

Released: 12-Feb-2021 11:25 AM EST
Studies highlight 'unprecedented and unique dangers' for children during COVID-19
University of Alabama at Birmingham

Two new studies investigating child maltreatment during the COVID-19 pandemic reveal "concerning results" that confirm warning signs seen early in the pandemic, according to researchers at UAB and the University of Michigan.

Released: 9-Feb-2021 11:45 AM EST
UAB, PathCheck Foundation, launch interactive vaccination dashboard
University of Alabama at Birmingham

A new interactive dashboard from UAB and PathCheck Foundation will enable users to see the quantity and location of vaccines distributed across the country and world in real time.

Released: 5-Feb-2021 4:35 PM EST
The truth, or fake news? How to do the research yourself with deception expert Tim Levine
University of Alabama at Birmingham

The world has many different information streams now. Levine shares his strategy for deciphering facts from fiction, no matter the topic.

Released: 27-Jan-2021 11:55 AM EST
UAB-developed research tool will help scientists better understand COVID-19
University of Alabama at Birmingham

PAGER-CoV is a database packed with nearly 12,000 (so far) pieces of genetic information on the SARS-CoV-2 virus, information that researchers and physicians can use to tailor treatments against the disease.

   
Released: 2-Dec-2020 4:10 PM EST
New activity found for CHD7, a protein factor vital in embryonic development
University of Alabama at Birmingham

Researchers inactivated the gene for CHD7 — whose mutation causes congenital birth defects — in mouse embryos, and then rigorously probed how this change in developing cardiac neural crest cells caused severe defects in the outflow tract and great arteries, leading to perinatal lethality.

Released: 25-Nov-2020 11:05 AM EST
COVID-19 vaccine candidate tested preclinically at UAB nears first clinical test in people
University of Alabama at Birmingham

Maryland-based Altimmune Inc., a clinical stage biopharmaceutical company, has submitted an Investigational New Drug, or IND, application to the United States Food and Drug Administration to commence a Phase 1 clinical study of its single-dose intranasal COVID-19 vaccine candidate, AdCOVID.

Released: 16-Nov-2020 4:10 PM EST
Keep Moving and Stay Connected: Tips for Taking Care of Older Loved Ones During a Pandemic
University of Alabama at Birmingham

Mask orders. Constant cleaning. Quarantine. The COVID-19 pandemic has completely changed how many people live. This can be especially true for older adults. As one of the most at-risk populations for COVID-related complications, many older adults have been forced to isolate themselves, causing decreased physical and mental activity.

Released: 11-Nov-2020 4:10 PM EST
Novel population of neurons identified that control binocular eye movements in 3D space
University of Alabama at Birmingham

Researchers have discovered a previously undescribed set of neurons called saccade-vergence burst neurons that help control our eyes as they view in three-dimensional space. Models had predicted the existence of such neurons, which are in the mid-brain’s central mesencephalic reticular formation.

Released: 4-Nov-2020 10:55 AM EST
Alabama Symphony Orchestra musicians perform virtual concerts for sickest COVID-19 patients at UAB Hospital
University of Alabama at Birmingham

During the COVID-19 pandemic, the sickest patients at the University of Alabama at Birmingham Hospital have had their troubles eased, however briefly, thanks to an innovative musical project. Helping those patients recover — and keeping their spirits up amid the isolation the virus requires — is the motivation for the project, an effort between UAB health care staff and the Alabama Symphony Orchestra.

Released: 29-Oct-2020 11:35 AM EDT
Study highlights link between depressive symptoms and stroke risk
University of Alabama at Birmingham

People with multiple depressive symptoms have an increased risk for stroke, with new findings showing that individuals who scored higher on a test designed to measure depressive symptoms had a higher stroke risk than those with lower scores.

Released: 22-Oct-2020 2:05 PM EDT
Type 1 diabetes: Tannic acid encapsulation protects transplanted islets from rejection
University of Alabama at Birmingham

Transplanting cadaver pancreatic islets is a promising therapy for Type 1 diabetes, but a reactivated autoimmunity means low graft viability after five years. Research now shows that a protective coating of two biopolymers can delay allograft and autoimmune-mediated rejection in mouse models of T1D.

Released: 22-Oct-2020 10:55 AM EDT
Black individuals bear heavy burden of COVID-19 mortality, but key geographic disparities in health determinants exist
University of Alabama at Birmingham

A new study published in the Mayo Clinic Proceedings: Innovations, Quality & Outcomes by University of Alabama at Birmingham researchers showed that Black individuals have a disproportionately higher COVID-19 mortality burden across all of the United States, which is driven by a high incidence of COVID-19 infection. They found that there are key geographic differences in the distribution of health determinants and COVID-19 mortality patterns.

Released: 21-Oct-2020 2:10 PM EDT
Hospital closures in rural America means longer drive times for patients needing care
University of Alabama at Birmingham

For many rural Americans, especially those in the South or Southeastern areas of the country, it is taking longer to get to a hospital. Delays in reaching appropriate health care facilities could have a profound negative effect in cases of medical emergency.



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