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Newswise: Study explores the future of at-home cancer treatment
Released: 28-Mar-2024 12:00 PM EDT
Study explores the future of at-home cancer treatment
Keck Medicine of USC

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

Newswise: New Study Examines if ‘Inoperable’ Pancreatic Tumors Can Be Safely Removed
Released: 14-Mar-2024 12:00 PM EDT
New Study Examines if ‘Inoperable’ Pancreatic Tumors Can Be Safely Removed
Keck Medicine of USC

A clinical trial from Keck Medicine of USC aims to provide a surgical solution for patients with a form of advanced pancreatic cancer previously considered inoperable.

Newswise: Phase 3 CELLEBRATE Trial Testing Regenerative Stem Cell-Based Therapy to Improve Urinary Control for Women
Released: 11-Mar-2024 2:05 PM EDT
Phase 3 CELLEBRATE Trial Testing Regenerative Stem Cell-Based Therapy to Improve Urinary Control for Women
Vanderbilt University Medical Center

The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery.

Newswise: Off-the-shelf vaccine offers hope for pancreatic and colorectal cancer patients with KRAS mutations
Released: 23-Feb-2024 10:05 AM EST
Off-the-shelf vaccine offers hope for pancreatic and colorectal cancer patients with KRAS mutations
University of California, Los Angeles (UCLA), Health Sciences

Samara Rahman, 74, enrolled in a clinical trial at UCLA Health that was evaluating an “off-the-shelf” vaccine that is given after surgery to prevent or delay the cancer from coming back in high-risk patients.

Released: 14-Feb-2024 4:05 AM EST
Can Olive Oil Reverse Genetic Predisposition for Alzheimer’s?
Alzheimer's Center at Temple University Lewis Katz School of Medicine

Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.

Released: 2-Feb-2024 11:05 AM EST
Speech Accessibility Project begins recruiting people who have had a stroke
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project has begun recruiting U.S. and Puerto Rican adults who have had a stroke.

   
Newswise: UTHealth Houston opens recruitment in RISE-UP clinical drug trial for people with sickle cell anemia
Released: 18-Jan-2024 6:05 PM EST
UTHealth Houston opens recruitment in RISE-UP clinical drug trial for people with sickle cell anemia
University of Texas Health Science Center at Houston

A medication that appeared to stabilize the function and shape of red blood cells in an earlier study for patients with sickle cell disease is now part of a Phase III clinical trial that is open for enrollment at UTHealth Houston.

Released: 16-Jan-2024 7:05 AM EST
Can recycled pacemakers from the U.S. save lives overseas? Study seeks to find out
Michigan Medicine - University of Michigan

For years, researchers and clinicians at University of Michigan have sent recycled, or reconditioned, pacemakers to low- and middle-income countries for compassionate use cases in 2010 through the “My Heart Your Heart” program. Currently, the U-M team is leading an international clinical trial that is testing the impact of sending reconditioned pacemakers abroad for standard use. If successful, the trial could greatly increase access to pacemaker treatment for patients who otherwise would not receive it.

Released: 12-Jan-2024 10:15 AM EST
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the First in the Nation to Offer Patients a New Interventional Clinical Study
Hackensack Meridian Health

Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the first ALS care provider in the United States to offer patients a new interventional clinical study.

Newswise: Personalizing Lifestyle Interventions for Cancer Survivors
Released: 10-Jan-2024 5:05 PM EST
Personalizing Lifestyle Interventions for Cancer Survivors
Sylvester Comprehensive Cancer Center

Researchers with Sylvester Comprehensive Cancer Center have received funding to better understand how personalized nutrition and exercise programs can improve quality of life after cancer treatment.

Released: 9-Jan-2024 12:05 PM EST
Voice recognition project recruiting adults with cerebral palsy
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project is now recruiting U.S. and Puerto Rican adults with cerebral palsy.

     
Newswise: UTSW-led studies are largest ever for stimulant use disorders
Released: 7-Dec-2023 3:05 PM EST
UTSW-led studies are largest ever for stimulant use disorders
UT Southwestern Medical Center

UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.

Released: 21-Nov-2023 10:05 AM EST
SLU Researcher Finds Help for Alzheimer’s-Associated Agitation with New FDA-Approved Treatment
Saint Louis University

George T. Grossberg, M.D., and colleagues were instrumental in developing the first and only Food and Drug Administration (FDA) approved treatment for agitation associated with Alzheimer's dementia.

Released: 9-Nov-2023 3:05 PM EST
Speech Accessibility Project now recruiting adults with Down syndrome
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project is now recruiting U.S. adults with Down syndrome. The project aims to make voice recognition technology more useful for people with diverse speech patterns and different disabilities.

   
Newswise: New, Promising Clinical Trial for Glioblastoma Starting at UNC Health
Released: 7-Nov-2023 1:05 PM EST
New, Promising Clinical Trial for Glioblastoma Starting at UNC Health
University of North Carolina Health Care System

UNC Health is the only academic healthcare system in North Carolina and the South participating in the randomized trial, which aims to assess the safety and efficacy of a combination immunotherapy for newly diagnosed glioblastoma patients.

Released: 2-Nov-2023 8:55 AM EDT
Can acupuncture alleviate certain kinds of chest pain?
University of Illinois Chicago

$3.12 million NIH study to look at acupuncture as a treatment for stable angina

Newswise: Are New Therapies on the Horizon for Painful Skin Condition?
Released: 17-Oct-2023 8:00 AM EDT
Are New Therapies on the Horizon for Painful Skin Condition?
University of California, San Francisco (UCSF)

Chronic inflammation of the skin, or Hidradenitis Suppurativa (HS), disproportionately affects women and people of color. It can be debilitating, negatively impacting suffers’ quality of life, physical function, work productivity, and the social and emotional wellbeing.

Released: 12-Oct-2023 5:05 PM EDT
SLU Researchers Enroll Football Coaches in Injury Prevention Study
Saint Louis University

Researchers at Saint Louis University (SLU) are enrolling participants in a clinical trial to increase youth sport coaches' knowledge of musculoskeletal injuries and how to prevent them. Principal investigator Oluwatoyosi Owoeye, Ph.D., assistant professor of physical therapy at SLU, says this is the first study of its kind.

Newswise:Video Embedded why-breast-cancer-clinical-trials-need-to-include-more-black-women
VIDEO
Released: 28-Sep-2023 2:05 PM EDT
Why Breast Cancer Clinical Trials Need to Include More Black Women
Rutgers Cancer Institute of New Jersey

Researchers are working to improve outcomes for Black women with breast cancer – including through increased participation in clinical trials, which helps find better ways to prevent, diagnose and treat cancer.

Newswise: University of Pittsburgh Launches Trial Tackling Leading Cause of Death in Kids
Released: 21-Sep-2023 10:05 AM EDT
University of Pittsburgh Launches Trial Tackling Leading Cause of Death in Kids
University of Pittsburgh

The Trauma and Transfusion Medicine Research Center (TTMRC) in the Department of Surgery at the University of Pittsburgh School of Medicine is launching a $34 million, federally funded clinical trial to simultaneously test multiple interventions for life-threatening bleeding in at least 1,000 traumatically injured children across 20 U.S. pediatric trauma centers.

Released: 8-Sep-2023 12:05 PM EDT
UChicago leads next phase of NIH program to advance precision medicine for ‘All of Us’ program in Illinois
University of Chicago Medical Center

Researchers from UChicago will lead the next phase of the Illinois Precision Medicine Consortium (IPMC)'s participation in the National Institutes of Health's All of Us Research Program.

Newswise: Bone healing research shows promise in treating malignant cancers
Released: 5-Sep-2023 9:55 AM EDT
Bone healing research shows promise in treating malignant cancers
University of the Witwatersrand, Johannesburg

Wits Bone Research Lab the only unit of its kind to show that a bone-forming protein can block growth of human squamous cell

Newswise: Speech Accessibility Project recruiting people with Parkinson’s
21-Aug-2023 12:05 AM EDT
Speech Accessibility Project recruiting people with Parkinson’s
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson’s. Project participant and Parkinson's advocate Ethan Henderson can comment.

Newswise: Clinical Trial Studying Possible New Treatment Option for Patients with NAFLD
Released: 23-Aug-2023 11:05 AM EDT
Clinical Trial Studying Possible New Treatment Option for Patients with NAFLD
UC San Diego Health

$9 million grant awarded to researchers with UC San Diego School of Medicine supports new study of semaglutide for liver disease.

Released: 21-Aug-2023 2:05 PM EDT
Volunteers Sought for Stroke Study
RUSH

Researchers at RUSH are seeking volunteers to explore how a change in diet may improve brain health after a stroke. The study, called NOURISH — short for Nutrition Effects on Brain Outcomes and Recovery in Stroke After Hospitalization — aims to prevent cognitive and memory decline that is common in stroke survivors.

Released: 15-Aug-2023 8:50 AM EDT
FDA Approves HEPZATO Kit to Treat Metastatic Ocular Melanoma
Moffitt Cancer Center

The Food and Drug Administration announced yesterday the approval of HEPZATO Kit to treat ocular melanoma that has spread to the liver. HEPZATO uses a hepatic delivery system to inject the chemotherapy drug melphalan into the liver, a procedure referred to as percutaneous hepatic perfusion (PHP). Moffitt Cancer Center’s Jonathan S. Zager, M.D., was the lead international principal investigator on the multinational FOCUS phase 3 clinical trial to test the procedure, which is manufactured by Delcath Systems, Inc.

Released: 11-Aug-2023 9:55 AM EDT
UTHealth Houston joins SATURN trial, studying role of statins in recurrent intracerebral hemorrhage
University of Texas Health Science Center at Houston

A clinical trial evaluating the role of statins in the risk of recurrent intracerebral hemorrhage (ICH) in patients presenting with ICH, has opened for enrollment at UTHealth Houston.

Released: 9-Aug-2023 10:55 AM EDT
PAN-TB Collaboration Announces the Start of a Phase 2 Clinical Trial to Evaluate Two Novel Tuberculosis Treatment Regimens
The Project to Accelerate New Treatments for Tuberculosis

The Project to Accelerate New Treatments for Tuberculosis (PAN-TB) collaboration announced today the start of a phase 2b/c clinical trial, sponsored by the Bill & Melinda Gates Medical Research Institute (Gates MRI).

Newswise: Clinical Trial Aims to Reduce Depression, Improve Quality of Life After Stroke
Released: 8-Aug-2023 9:00 AM EDT
Clinical Trial Aims to Reduce Depression, Improve Quality of Life After Stroke
University of Utah Health

Following up on positive results from preliminary research, scientists at University of Utah Health are evaluating whether an eight-week program based on positive psychology techniques can improve the mood and well-being of people who have had a stroke and those who care for them.

Released: 31-Jul-2023 12:15 PM EDT
UTHealth Houston set to enroll patients for two long COVID clinical trials through NIH
University of Texas Health Science Center at Houston

Two clinical trials that will evaluate drugs, biologics, medical devices, and other therapies for long COVID that are sponsored by the National Institutes of Health (NIH) will launch at UTHealth Houston.

Released: 31-Jul-2023 12:00 PM EDT
Duke Clinical Research Institute launches long COVID trials through NIH RECOVER Long COVID Initiative
Duke Clinical Research Institute

Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months. Treatments will include drugs, biologics, medical devices and other therapies.

Released: 12-Jul-2023 2:30 PM EDT
Velico Medical begins clinical trial on Spray Dried Plasma
Velico Medical, Inc

Velico Medical has begun a Phase I safety study for their FrontlineODP (OnDemandPlasma) Spray Dried Plasma product in a multi-center, dose escalation clinical trial.

Released: 26-Jun-2023 8:05 AM EDT
Overlook Medical Center chosen as trial site for brain tumor treatment
Atlantic Health System

Overlook Medical Center in NJ, is the 1st site in the nation to dose a patient in the Phase IIb RESTORE Trial for newly-diagnosed glioblastoma tumors. Researchers will see whether using NanO2 TM, a drug by NuvOx Pharma to infuse oxygen into hypoxic tissues, can boost traditional radiation and chemo.

Released: 23-Jun-2023 3:05 PM EDT
Mpox Vaccine Trial for Adolescents, Children Begins at UM School of Medicine
University of Maryland School of Medicine

A 2022 outbreak of mpox (formerly monkeypox) sickened more than 30,000 people and caused 38 deaths in the United States. It highlighted the lack of an approved vaccine for those under 18 years old.

Released: 14-Jun-2023 10:05 AM EDT
Multi-city trial will use community centers to bring treatment to Black opioid users 
University of Illinois Chicago

A new clinical trial run by Howard University, the University of Illinois Chicago and the University of Miami Miller School of Medicine will partner with community organizations and sites to bring life-saving care closer to a highly vulnerable population – Black people with opioid use disorder.

Released: 2-Jun-2023 8:05 AM EDT
ASCO: Adding ribociclib to hormone therapy improves outcomes in patients with early breast cancer
University of California, Los Angeles (UCLA), Health Sciences

A study involving UCLA Jonsson Comprehensive Cancer Center researchers found when ribociclib, a targeted therapy drug, is added to hormone therapy there are significant survival benefits for patients with early hormone-receptor (HR) positive/HER2 negative breast cancer.

30-May-2023 10:25 AM EDT
Liver dialysis device proved safe and effective for treating severe liver failure
University College London

The first successful in-patient trial of liver dialysis* has been completed by researchers from UCL, the Royal Free Hospital, UCL spin-out Yaqrit and their collaborators.

Released: 9-May-2023 8:55 AM EDT
Can aspirin reduce heart attack and stroke risk in patients with pneumonia?
University of Bristol

A pneumonia trial – the largest ever led by the University of Bristol – will investigate whether aspirin can reduce the risk of a heart attack or stroke in patients who are admitted to hospital with pneumonia.

Released: 27-Apr-2023 2:30 PM EDT
Society for Clinical Trials Presents CHAP Trial with Prestigious David Sackett Trial of the Year Award
Society for Clinical Trials

The Society for Clinical Trials (SCT) is pleased to announce that the prestigious David Sackett Trial of the Year Award will be presented to The Chronic Hypertension and Pregnancy (CHAP) Trial.

Released: 24-Apr-2023 6:05 PM EDT
UCLA Health seeks participants for first-of-its-kind study using injectable buprenorphine to treat methamphetamine use disorder and opioid co-use
University of California, Los Angeles (UCLA), Health Sciences

UCLA Health investigators are leading a new, six-city trial of injectable buprenorphine for treatment of methamphetamine use disorder in adults who also use opioids.

Released: 19-Apr-2023 2:15 PM EDT
Clinical trial begins using CAR T cells to potentially cure HIV
UC Davis Health

UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CART-cell therapy.

Newswise: NIH Trial Evaluating Mpox Vaccine in Adolescents
Released: 19-Apr-2023 9:30 AM EDT
NIH Trial Evaluating Mpox Vaccine in Adolescents
George Washington University

The National Institutes of Health trial to evaluate the mpox (previously known as monkeypox) vaccine JYNNEOS has now entered the next stage and is studying the immune responses to and the safety of the vaccine in adolescents. The George Washington University is one of 18 clinical trial sites across the United States that have launched this stage testing the JYNNEOS vaccine.

Released: 18-Apr-2023 3:05 PM EDT
Immunotherapy Drug Development Pipeline Shifts from Traditional Therapies to Newer Modalities
Cancer Research Institute

The immuno-oncology (IO) clinical trial landscape is shifting in new directions. While the number of total clinical trials is down, there are healthy signs of innovation.

Newswise:Video Embedded clinical-trial-investigating-innovative-way-to-control-type-2-diabetes
VIDEO
Released: 16-Mar-2023 10:05 AM EDT
Clinical trial investigating innovative way to control Type 2 diabetes
Keck Medicine of USC

Keck Medicine of USC has launched a Phase 2 clinical trial investigating the effectiveness of a new outpatient, nonsurgical endoscopic procedure in stabilizing blood glucose levels for patients.

Newswise: Can hormone replacement therapy protect the heart and brain after menopause?
Released: 9-Mar-2023 10:05 AM EST
Can hormone replacement therapy protect the heart and brain after menopause?
Keck Medicine of USC

Keck Medicine of USC has launched a clinical trial to study the effect of a novel hormone replacement therapy on postmenopausal cardiovascular disease and cognitive decline.

Released: 7-Mar-2023 10:05 AM EST
Cornell-developed anti-TB compound headed to trials
Cornell University

A novel compound that has the potential to starve the bacteria that causes tuberculosis – the world’s leading infectious killer after SARS-CoV2 – is entering human clinical trials.

Released: 27-Feb-2023 5:05 PM EST
Taking Aim at Prostate Cancer
University of New Mexico Comprehensive Cancer Center

The UNM Cancer Center will be one of a few sites in the country participating in a clinical trial to expand the application of theranostic treatment to patients with prostate cancer. This type of treatment is currently used at the cancer center for neuroendocrine tumors. The treatment is a two-part process that first injects the molecule attached to a gallium-68 radioactive isotope that can be imaged to illuminate the cancer cells, which makes them easier to see under Positron Emission Tomography, or PET scans.

Newswise: FAU, Delray Medical Center, Insightec Team Up on Groundbreaking Alzheimer’s Study
Released: 17-Feb-2023 8:30 AM EST
FAU, Delray Medical Center, Insightec Team Up on Groundbreaking Alzheimer’s Study
Florida Atlantic University

Delray Medical Center is the first hospital in Florida to treat an Alzheimer’s disease patient using non-invasive focused ultrasound technology as part of a groundbreaking study being conducted in collaboration with FAU’s Institute for Human Health and Disease Intervention (I-Health). In the FDA-approved clinical trial, focused ultrasound technology is used to disrupt the blood-brain barrier in participating Alzheimer’s patients.

Newswise: Vanderbilt Enrolling Participants for Early Alzheimer’s Study
Released: 24-Jan-2023 12:25 PM EST
Vanderbilt Enrolling Participants for Early Alzheimer’s Study
Vanderbilt University Medical Center

The Vanderbilt Memory and Alzheimer’s Center is recruiting individuals age 50 and older to participate in a study researching early drivers of Alzheimer’s disease.


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