Researchers conducted a systematic assessment of more than 200,000 scientific publications to understand the breadth and diversity of biological pathways that contribute to Alzheimer’s disease by research over the last 30 years.
In a letter published in the New England Journal of Medicine, physician-scientists report that the three Omicron subvariants currently dominant in the United States – officially known as subvariants BA.2.12.1, BA.4, and BA.5 – substantially escape neutralizing antibodies induced by both vaccination and previous infection.
Endocrinologists have identified a key enzyme in the synthesis of a new class of lipids (or fats), called FAHFAs, that are made in human tissues and have beneficial effects on insulin sensitivity, blood sugar control and other metabolic-related parameters in humans and mice. The discovery, published in Nature, opens the door to potential new treatments for Types 1 and 2 diabetes.
While earlier guidelines had restricted screening to only those individuals with BRCA 1/2 who had a family history of pancreatic cancer, the new guidelines expand indication for screening for all with the gene variations regardless of family history.
In a new paper published in JAMA, researchers evaluated mental health and substance use among homeless and housed high school students surveyed voluntarily and anonymously in 2019.
In a recent study, scientists at the Harvard T.H. Chan School of Public Health and Beth Israel Deaconess Medical Center used live virus culture to assess how well four rapid antigen tests are able to detect these COVID variants of concern.
Scientists sought to determine whether high blood glucose blunts the body’s response to exercise and whether lowering it can restore the ability to improve aerobic capacity with training.
Joslin Diabetes Center, the preeminent institution for diabetes research and care, affiliated with Harvard Medical School and a part of Beth Israel Lahey Health, has again been awarded $8.5 million from the National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases (NIH/NIDDK) in continued support for Joslin’s Diabetes Research Center (DRC) program. The grant, which officially began April 1, 2022, marks the 36th continuous year of NIH investment in Joslin’s DRC.
Northshore Magazine has named 13 physicians and surgeons from 11 medical specialties affiliated with Winchester Hospital to its annual ‘Top Doctors’ guide. Drawing from a Castle Connolly Medical Ltd. Physician database, the list consists of Northshore-area physicians and is available in the printed version or online subscription of Northshore Magazine.
Northshore Magazine has named 125 physicians and surgeons from 32 medical specialties affiliated with Lahey Hospital & Medical Center to its annual ‘Top Doctors’ guide. Drawing from a Castle Connolly Medical Ltd. Physician database, the list consists of Northshore-area physicians and is available in the printed version or online subscription of Northshore Magazine.
Northshore Magazine has named 10 physicians and surgeons from 6 medical specialties affiliated with Anna Jaques Hospital to its annual ‘Top Doctors’ guide. Drawing from a Castle Connolly Medical Ltd. Physician database, the list consists of Northshore-area physicians and is available in the printed version or online subscription of Northshore Magazine.
Reflecting on two years of the COVID-19 pandemic and its impact on society, we asked experts across Beth Israel Lahey Health about managing another year of the unknown, how to shore up our mental resources to heal from what we’ve been through and how to prepare for whatever may lie ahead.
Scientists have generated an atlas of the cell types present in the white adipose tissue of humans and in mice, allowing them to look at the composition of fat in unprecedented detail.
Joslin Diabetes Center is pleased to announce that Chief Scientific Officer George L. King, MD, has been named the inaugural incumbent of the Thomas J. Beatson, Jr. Professorship in the Field of Diabetes at Harvard Medical School.
Beth Israel Lahey Health announced the opening of an on-site pharmacy at Bowdoin Street Health Center that will expand access to convenient medications for the health center’s approximately 11,000 patients other members of the Bowdoin-Geneva community in Massachusetts.
A new study demonstrates that cellular immunity induced by current COVID-19 vaccines provided robust protection against severe disease caused by both the Delta and Omicron variants.
Beth Israel Lahey Health and Cape Cod Healthcare announced plans for a broad affiliation that will expand access to comprehensive care for patients, families and visitors on Cape Cod in Massachusetts.
In a nationwide study of Medicare beneficiaries, researchers evaluated differences in procedural care and mortality for acute cardiovascular conditions between rural and urban hospitals.
In a new meta-analysis of randomized, placebo-controlled COVID-19 vaccine trials, researchers compared the rates of adverse events reported by participants who received the vaccines to the rates of adverse events reported by those who received a placebo injection.
Physician-scientists at Beth Israel Deaconess Medical Center reported that a common type of N95 respirator reprocessed with VHP maintained its function and effectiveness through 25 cycles of re-use.
In a pair of papers and a guest editorial published in Dimensions of Critical Care Nursing, nurse-scientists share their experiences nearly doubling the hospital’s intensive care unit capacity; identifying, training and redeploying staff; and developing and implementing a proning team to manage patients with acute respiratory distress syndrome during the first COVID-19 surge.
Researchers at Beth Israel Deaconess Medical Center (BIDMC) conducted a head-to-head test of the second-generation vaccine CV2CoV compared with CVnCoV. The scientists assessed the vaccines’ ability to provoke an immune response as well as their protective efficacy against COVID-19 in non-human primates.
A new study suggests that because of improvements in stent technology and changes in the types of patients receiving stents, the risks of DAPT may now outweigh the benefits for the average patient.
A new analysis by a researcher at Beth Israel Deaconess Medical Center (BIDMC) finds a link between large gatherings of unvaccinated county residents – both students and non-students – and an increase in COVID-19 infections in the university’s community.
In a paper published in the New England Journal of Medicine, a team of experts at Beth Israel Deaconess Medical Center compared immune responses induced by the three COVID-19 vaccines over an eight-month follow-up period.
Researcher-physicians at Beth Israel Deaconess Medical Center used a novel, highly-sensitive test to measure the amount of toxin produced by C. difficile in the stool of patients with suspected infections.
Physician-scientists from Beth Israel Deaconess Medical Center developed a 12-week mind-body program that takes a new approach to chronic back pain. The team demonstrated that the mind-body intervention was highly beneficial for treating back pain when compared to standard care
In the first randomized trial examining the role of a deep-learning based computer-aided detection system during colonoscopy in the U.S., researchers reported a relative reduction of the miss rate by nearly a third when computer-aided detection was used in conjunction with standard-of-care colonoscopy.
In a research letter in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) found that the vast majority of patients who had a diagnosis of either cognitive impairment, Alzheimer’s disease, or Alzheimer’s disease related disorders, including cardiovascular disease, prior stroke, use of blood thinners, and age over 85 years, would have been excluded them from the aducanumab clinical trials.
A new analysis by a team of physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) provides the first evidence that monoclonal antibodies were indeed underutilized in the first six months of FDA authorization.
Researchers uncovered the precise hypothalamic neurons that regulate the drive to engage in mating behaviors in mice. The study sets the stage for developing a targeted therapy to offset the sexual side effects linked to antidepressants that can discourage patients from treating mental illnesses.
Researchers systematically reviewed federally funded cardiovascular disease trials run between 2000 and 2019 to determine whether various recruitment strategies impacted the number of Black participants enrolled.
A team led by Dan H. Barouch, MD, PhD, has been awarded $4.9 million in annual funding over the next five years to find a cure for HIV. Barouch was one of ten primary investigators to receive a 2021 National Institutes of Health (NIH) Martin Delaney Collaboratories for HIV Cure Research award, which aims to expedite human immunodeficiency virus (HIV) cure research by bringing together research partners in academia, government, the private sector and the community; coordinating complex research studies, and mentoring the next generation of HIV cure researchers.
Researchers conducted the largest and longest observational study to date, using multiple body weight measurements among a racially and ethnically diverse population of gender diverse individuals treated at an academic medical center and non-profit community health center in Washington, D.C. The findings suggest that transgender patients taking gender-affirming hormone therapy should be monitored for changes in body weight, body mass index and for complications that may accompany high body weight, such as cardiovascular disease.
In a real-world trial, a team of clinician-researchers at Beth Israel Deaconess Medical Center have demonstrated that tests of self-collected saliva provided comparable results to tests performed by trained healthcare professionals using NP swabs.
With the goal of dramatically accelerating discoveries in health and disease, Beth Israel Deaconess Medical Center has opened a Spatial Technologies Unit, the first center in Massachusetts and one of the first of its kind worldwide. The new space will provide access to ground-breaking technologies that allow scientists to examine cells as they function within intact tissues. Made possible by a grant from the Massachusetts Life Sciences Center, the BIDMC unit will be a nexus of the state’s precision medicine community, empowering researchers across healthcare, academia, research and industry.
A study conducted by clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) found older patients with chronic conditions and their caregivers can benefit from accessing their medical appointment notes.
In a new study, a multi-disciplinary team of researchers has demonstrated that a metabolic regulatory molecule called Them1 prevents fat burning in cells by blocking access to their fuel source, which may contribute to the development of a new type of obesity treatment.