Researchers at Albert Einstein College of Medicine have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer. The drug was tested in rats, and the findings were published online today in JCI Insight.
Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population—but their ability to do so depends on their type of cancer and the treatments they’ve received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of Medicine. The findings, published online today in Nature Cancer, may lead to better care for cancer patients, who face a heightened risk of dying from COVID-19, and suggests that cancer patients should respond well to COVID-19 vaccines.
People hospitalized with COVID-19 and neurological problems including stroke and confusion, have a higher risk of dying than other COVID-19 patients, according to a study published online today by researchers at Montefiore Health System and Albert Einstein College of Medicine in the journal Neurology®, the medical journal of the American Academy of Neurology. These findings have the potential to identify and focus treatment efforts on individuals most at risk and could decrease COVID-19 deaths.
A team of scientists from Albert Einstein College of Medicine has received a five-year, $4.9 million grant from the National Institutes of Health (NIH) to establish a research center to investigate HIV- and human papillomavirus (HPV)-related cancers in Africa.
According to the National Institute of Mental Health (NIMH), in 2017 approximately 13% of adolescents in the United States, or 3.2 million children aged 12 to 17, had at least one major episode of depression. While many recover from such an episode, a significant portion will develop severe depression or a chronic mood disorder. There is an urgent need to identify adolescents who are at higher risk for serious problems and may benefit from aggressive treatment.
Joe Verghese, M.B.B.S., M.S., an international leader in aging and cognition research at Albert Einstein College of Medicine and Montefiore Health System, has received two grants from the National Institutes of Health totaling $13.8 million to conduct studies on pre-dementia and Alzheimer’s disease.
The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives—but an unfortunate consequence of people living longer with HIV is an increased risk of cancer. For 25 years, the AIDS Malignancy Consortium (AMC) has led national and international efforts to prevent and treat of HIV-related cancers. Now, Montefiore Health System and Albert Einstein College of Medicine have received a five-year, $111 million grant from the National Cancer Institute (NCI) to lead this research consortium.
The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults. The findings also have important implications for vaccines and drugs being developed to curb COVID-19. The study was published today in Science Translational Medicine and was conducted by scientists at Albert Einstein College of Medicine, Children’s Hospital at Montefiore (CHAM), and Yale University.
Chemotherapy usually cures children diagnosed with acute lymphoblastic leukemia (ALL), but the treatment may hamper brain development and impact key cognitive functions including sensory processing, memory, and attention. Researchers at Albert Einstein College of Medicine, Children’s Hospital at Montefiore (CHAM), and Rutgers Cancer Institute of New Jersey have received a five-year, $4.6 million grant from the National Institutes of Health (NIH) to determine how chemotherapy exerts its damaging effects on the brain. Their long-term objective is to use this information to develop protective interventions that can prevent permanent harm.
A new study shows how chronic psychological stress leads to painful vessel-clogging episodes—the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible ways to prevent them. The research was conducted by scientists at Albert Einstein College of Medicine and published online today in Immunity.
Britta Will, Ph.D., assistant professor of medicine and of cell biology at Albert Einstein College of Medicine, has won a 2020 Pershing Square Sohn Prize for Young Investigators in Cancer Research. Dr. Will is one of seven New York City area-based scientists to receive the prestigious award, which provides $600,000 over three years for innovative basic science cancer research.
Earle Chambers, Ph.D., M.P.H., has been appointed director of the division of research in the department of family and social medicine at Albert Einstein College of Medicine and Montefiore Health System. In this role, Dr. Chambers will help determine the priorities and focus of the department’s research agenda and manage the resources available for the research faculty. He is currently an associate professor of family and social medicine and of epidemiology & population health, and a member of the leadership team for the New York Regional Center for Diabetes Translation Research at Einstein.
Albert Einstein College of Medicine has received a $9.5 million, five-year grant from the National Institutes of Health (NIH) to support the Einstein-Mount Sinai Diabetes Research Center (ES-DRC). The multi-institutional center is a leader in basic, translational, clinical, and community-based research and training in type 1 and type 2 diabetes, obesity, and other metabolic disorders.
Montefiore Health System and Albert Einstein College of Medicine have begun the next stage of the Adaptive COVID-19 Treatment Trial (ACTT), to evaluate treatment options for people hospitalized with severe COVID-19 infection. The new iteration of the trial, known as ACTT 2, is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
While most children infected with the novel coronavirus have mild symptoms, a subset requires hospitalization and a small number require intensive care. A new report from pediatric anesthesiologists, infectious disease specialists and pediatricians at the Children’s Hospital at Montefiore (CHAM) and Albert Einstein College of Medicine, describes the clinical characteristics and outcomes of children hospitalized with COVID-19, during the early days of the pandemic.
Montefiore Health System, Albert Einstein College of Medicine and NYU Langone have launched a new clinical trial to study if convalescent plasma—taken from people who have recovered from COVID-19—is effective in treating the disease.
Researchers at Montefiore Health System and Albert Einstein College of Medicine have begun testing the drug hydroxychloroquine for the treatment of COVID-19, as part of a nationwide trial sponsored by the National Heart, Lung, and Blood Institute (NHLBI).
Answering the call for additional medical workers to join the frontlines of the COVID-19 pandemic, today more than 100 medical students at Albert Einstein College of Medicine graduated a month early. Many of will immediately join the staff of hospitals in New York City.
Researchers at Montefiore Health System and Albert Einstein College of Medicine showed for the first time that men clear the novel coronavirus from their bodies slower than women and found a possible explanation: a potential male-only “reservoir” for coronavirus.
Montefiore Health System and Albert Einstein College of Medicine has joined a clinical trial to evaluate the experimental drug remdesivir to treat people who are hospitalized with severe COVID-19 infection.
Researchers at Albert Einstein College of Medicine secured $178 million from the National Institutes of Health in federal fiscal year 2019, marking the largest annual total in the institution’s history (excluding supplemental stimulus funding distributed as a part of the American Recovery and Reinvestment Act of 2009). Major grants included those to lead international consortiums to study Ebola and HIV, as well as those focusing on neuroscience, genetics, and improving health among minority groups.
Albert Einstein College of Medicine and the CUNY Graduate School of Public Health and Health Policy (CUNY SPH) announced an agreement today to offer Einstein medical students an opportunity to complete a five-year program resulting in a Doctor of Medicine (M.D.) degree from Einstein and a Master’s Degree in Public Health (M.P.H.) degree from CUNY SPH.
A study of New York City firefighters finds that exposure to 9/11 World Trade Center (WTC) dust is associated with an increased risk of cardiovascular disease (CVD). Researchers at Albert Einstein College of Medicine, Montefiore Health System, and the Fire Department of the City of New York (FDNY) report in JAMA Network Open that those who arrived first at the WTC site have a 44% increased risk of CVD compared to those who arrived later.
Members of Albert Einstein College of Medicine’s class of 2023 received monogrammed white coats and stethoscopes last week in a ceremony marked with pride and reminders of responsibility as they embark on their lifelong journey of medical education.
In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism. The study includes adults of both sexes and reveals substantial differences between them.
The National Institutes of Health (NIH) has awarded a seven-year, $23 million grant to researchers at Albert Einstein College of Medicine and Montefiore Health System to study HIV and the chronic illnesses that often accompany HIV infection, including cardiovascular and lung disease, diabetes, and cancer.
Dr. Sanjay Gupta, CNN’s chief medical correspondent, told graduates of Albert Einstein College of Medicine to embrace fear, savor opportunities to do the impossible, and practice empathy as they embark on what he called “the best job in the world.”
In research that could make biopsies more useful for many diseases, scientists have used a powerful new tool to zero in on individual cells in a patient’s diseased organ and reveal the cells’ underlying glitches in gene expression—information that may allow for more precise and effective treatment. The findings, by scientists at Albert Einstein College of Medicine, Montefiore Health System, and other medical institutions, are published online today in Nature Immunology.
Sanjay Gupta, M.D., CNN’s award-winning chief medical correspondent, will deliver the keynote address at the 2019 commencement ceremony for Albert Einstein College of Medicine. Dr. Gupta, a practicing neurosurgeon, has covered major health stories from around the world, including the successful 27-hour surgical separation of conjoined twins Jadon and Anias McDonald at Children’s Hospital of Montefiore (CHAM) in 2016.
Ana Maria Cuervo, M.D., Ph.D., cell biologist and internationally recognized expert on the cellular process autophagy, has been elected to the National Academy of Sciences (NAS). Dr. Cuervo is professor of developmental and molecular biology, of anatomy and structural biology, and of medicine, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein.
Albert Einstein College of Medicine has been recognized by Forbes as one of the country’s best midsize employers in 2019.
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments.
Research in the past several years has shown that children can outgrow a diagnosis of autism spectrum disorder (ASD), once considered a lifelong condition. In a new study, researchers at Albert Einstein College of Medicine and Montefiore Health System have found that the vast majority of such children still have difficulties that require therapeutic and educational support. The study was published online today in the Journal of Child Neurology.
More than six decades after it first opened its doors, Albert Einstein College of Medicine is now an independent academic institution, with the authority to confer its own medical and graduate degrees. This achievement had been set in motion more than three years ago, when Yeshiva University entered into a strategic joint collaboration with longtime Einstein affiliate, Montefiore. Einstein’s academic independence is the result of a vote by the Board of Regents of New York State’s Department of Education, which awarded Einstein an absolute charter, establishing it as an autonomous educational institution.
In a study published online today in the journal Science, researchers at Albert Einstein College of Medicine, part of Montefiore, prove for the first time that the brain’s cerebellum—long thought to be mainly involved in coordinating movement—helps control the brain’s reward circuitry. The surprising finding indicates that the cerebellum plays a major role in reward processing and social behaviors and could potentially lead to new strategies for treating addiction.
Hantaviruses cause severe and sometimes fatal respiratory infections, but how they infect lung cells has been a mystery. In today’s issue of Nature, an international team including researchers at Albert Einstein College of Medicine reports that hantaviruses gain entry to lung cells by “unlocking” a cell-surface receptor called protocadherin-1 (PCDH1). Deleting this receptor made lab animals highly resistant to infection. The findings show that targeting PCDH1 could be a useful strategy against deadly hantavirus pulmonary syndrome (HPS).
By incorporating a gene-suppressing drug into an over-the-counter gel, researchers at Albert Einstein College of Medicine and their colleagues cut healing time by half and significantly improved healing outcomes compared to control treatments. Results from the combination therapy, which was tested in mice, were published online today in Advances in Wound Care.
Dr. Chinazo Cunningham, M.D., M.S., a New York City-based expert in opioid use disorder will serve on a national board advising the CDC on best approaches to address the nation's opioid epidemic.
Women’s brains are much more vulnerable than men’s to injury from repeated soccer heading, according to a new study by researchers at Albert Einstein College of Medicine, part of Montefiore. The study found that regions of damaged brain tissue were five times more extensive in female soccer players than in males, suggesting that sex-specific guidelines may be warranted for preventing soccer-related head injuries. The results were published online today in Radiology.
It’s been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today’s online edition of Nature, offers a novel approach for attacking many disease-causing viruses.
A study in today’s issue of JAMA Oncology reports that New York City firefighters exposed to the 9/11 World Trade Center disaster site face an increased risk for developing myeloma precursor disease (MGUS), which can lead to the blood cancer multiple myeloma. The study was conducted by researchers at Albert Einstein College of Medicine, Montefiore Health System, the Fire Department of the City of New York (FDNY) and Memorial Sloan Kettering Cancer Center.
Ever wonder why intense exercise temporarily curbs your appetite? In research described in today’s issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head—more specifically, your arcuate nucleus.
Worse cognitive function in soccer players stems mainly from frequent ball heading rather than unintentional head impacts due to collisions, researchers at Albert Einstein College of Medicine have found. The findings suggest that efforts to reduce long-term brain injuries may be focusing too narrowly on preventing accidental head collisions. The study published online today in the Frontiers in Neurology.
In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute myeloid leukemia (AML) and describe how the drug works at the molecular level. The findings have led to a Phase I/II clinical trial for patients with advanced AML and advanced myelodysplastic syndrome (MDS), now underway at Montefiore Health System.
A newly discovered family of viruses appears to play a major role in killing marine bacteria and maintaining the ocean’s ecology. Preliminary evidence suggests that related bacterial viruses also occur in the human gut. The study, by researchers at Albert Einstein College of Medicine and Massachusetts Institute of Technology (MIT), was published online today in the journal Nature.
Researchers at Albert Einstein College of Medicine, part of Montefiore, and Hackensack Meridian Health John Theurer Cancer Center at Hackensack University Medical Center have secured a five-year, $6.4 million grant from the National Institutes of Health (NIH) to identify biomarkers that can predict which women with pre-cancerous tissue in their breast will develop invasive breast cancer. This research could help personalize treatment and improve outcomes for tens of thousands of women each year.
The number of older adults with Alzheimer’s disease continues to rise, but the number of treatments for the condition has not kept pace. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have received a $6.3 million grant from the National Institutes of Health (NIH) to identify networks of genes in healthy centenarians that protect them against dementia. The results could help identify new targets for drugs to treat Alzheimer’s.
The National Institutes of Health has awarded Albert Einstein College of Medicine nutrition scientist Yasmin Mossavar-Rahmani, Ph.D., R.D., a five-year, $4 million grant to test whether a diet rich in foods with anti-inflammatory properties can reduce cognitive decline and Alzheimer's disease risk. Middle-aged and older participants from the Bronx will follow this diet, which is designed to appeal to a multicultural population, and researchers will measure cognitive function over time to assess its impact.
Albert Einstein College of Medicine researchers report that the composition of people’s gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal cancer. The findings, described online today in npj Biofilms and Microbiomes, a Nature research journal, could help predict which patients will suffer side effects and prevent complications in susceptible patients.
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