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The researchers will investigate how to design antibodies to deliver drugs to fight chronic lymphocytic leukemia.

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“As researchers, they take risks without knowing the answers...I really admire it.”

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The findings could shed light on sickle cell diseases and other disorders where red blood cells are deformed.

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Scientists at The Scripps Research Institute have discovered a new aspect of the flu virus and how it interacts with antibodies in the lungs.

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“This study is a good example of a host/pathogen arms race playing out in real-time—this time with the host a likely winner."

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The Skaggs Graduate School of Chemical and Biological Sciences at The Scripps Research Institute is ranked among the top ten in the nation according to a recent survey by U.S. News & World Report.

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TSRI scientists investigate a phenomenon that may guard against disease as we age.

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Researchers at The Scripps Research Institute (TSRI) have designed a new molecule-building method that uses sulfones as partners for cross-coupling reactions, or the joining of two distinct chemical entities in a programmed fashion aided by a catalyst.

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Scientists at The Scripps Research Institute (TSRI) have now shown a path to developing treatments for disease subtype CMT2D.

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‘This study identifies the missing link between Lewy bodies and the type of damage that’s been observed in neurons affected by Parkinson’s."

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Scientists on the Florida campus of The Scripps Research Institute (TSRI) have discovered a new target for treating major depressive disorder, a disease that affects more than 16 million American adults.

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The breakthrough may expand research on the roles of glycans in human diseases, including cancers.

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These new areas of interest belong to the so-called “non-coding” genome—the 98 percent of the genome that doesn’t directly code for proteins but instead regulates how key proteins are produced.

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A team from The Scripps Research Institute (TSRI) has revealed that by crossing two species of flies, they can use what they learn from the proteome of the hybrid offspring to find new clues about how proteins interact with each other

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“These results lay the groundwork for the next steps toward FDA approval,” says John Griffin, PhD, professor at TSRI, whose team invented 3K3A-APC.

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Researchers at The Scripps Research Institute (TSRI) have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.

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The researchers will spend the next five years collecting data from Ebola and Lassa survivors to learn how they fought off the virus.

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A study from scientists at The Scripps Research Institute (TSRI) explains why the risk of osteoarthritis increases as we age and offers a potential avenue for developing new therapies to maintain healthy joints.

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Scientists at The Scripps Research Institute (TSRI) have achieved a major milestone toward designing a safe and effective vaccine to both treat heroin addiction and block lethal overdose of the drug.

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Understanding how the dynein-dynactin complex is assembled and organized provides a critical foundation to explain the underlying causes of several dynein-related neurodegenerative diseases.

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TSRI scientists identify molecule that fuels cancer metastasis.

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The five-year grant will support five individual research projects and three core resources at the TSRI Alcohol Research Center.

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Scientists often struggle to predict how these cells will act in different environments in the body.

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Researchers from the Scripps Translational Science Institute (STSI) at The Scripps Research Institute (TSRI) have launched an open-access, peer-reviewed online journal—npj Digital Medicine.

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Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

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Scientists at The Scripps Research Institute have discovered the workings of the first promising treatment for Marburg virus, a pathogen with the same pandemic potential as Ebola virus.

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Following the chemistry, scientists develop fascinating new theory for how life on Earth may have begun.

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Nobel laureate Kurt Wüthrich investigates the structure of an important drug target.

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The findings point the way to targeting diseases where this protein is mutated.

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The scientists hope understanding how immune cells adapt as they enter different tissues will spur the design of better, more specific, medicines.

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"Eric is an esteemed colleague with a clear vision for integrating scientific discovery and translational medicine."

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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now uncovered new insights into the regulatory network behind neuron growth.

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Jeffery Kelly, Ph.D., co-chair of the Department of Molecular Medicine at The Scripps Research Institute (TSRI), has been named a fellow of the esteemed National Academy of Inventors (NAI), the organization announced today.

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New research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

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How do killer T cells “learn” to leave their home base and amass within specific tissues like the skin, gut, and lung, or solid tumors?

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A team of researchers from The Scripps Research Institute (TSRI) and Duke University has made the first determination of the atomic structure of Transient Receptor Potential Melastatin 8 (TRPM8), a molecular sensor in nerve ends that detects cold temperatures as well as menthol and other chemicals that induce cold sensations.

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Telenti is a leading data scientist and genomic researcher whose research foci include human genomics, as well as infectious disease research.

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This “semi-synthetic” strain of E. coli is the first to both contain unnatural bases in its DNA and use the bases to instruct cells to make a new protein.

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Understanding how brains actively erase memories may open new understanding of memory loss and aging, and open the possibility of new treatments for neurodegenerative disease.

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A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction—which can be caused by aging, pesticides and pollution—may contribute to Parkinson’s disease.

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The research shows that a range of compounds can deliver pain-blocking potency without affecting respiration.

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New research could boost the development of a more potent vaccine against the global killer.

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NitroSynapsin is intended to restore an electrical signaling imbalance in the brain found in virtually all forms of autism spectrum disorder (ASD).

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Celgene Corporation recently announced results from two phase 3 trials evaluating the efficacy and safety of the drug ozanimod. Ozanimod was invented by scientists at The Scripps Research Institute (TSRI).

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Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth.

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Egg-based production causes virus to target bird cells, making vaccine less effective.

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The MyGeneRank app allows individuals with genetic data from 23andMe to obtain an estimated genetic risk score for coronary artery disease.

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Scientists from the Florida campus of The Scripps Research Institute have created a new class of antibody-drug conjugates for cancer therapy.