A new study led by researchers from the UCLA Health Jonsson Comprehensive Cancer Center shows that using high doses of radiation while integrating an ablative radiotherapy technique called stereotactic ablative radiotherapy (SABR) concurrently with chemotherapy is safe and effective in treating people with locally advanced non-small cell lung cancer that is not suitable for surgery.
Scooter injuries nearly tripled across the U.S. from 2016 to 2020, with a concurrent increase in severe injuries requiring orthopedic and plastic surgery over the same period.
Embargoed research finds an average of 22 adolescents 14 to 18 years of age died in the U.S. each week in 2022 from drug overdoses, raising the death rate for this group to 5.2 per 100,000-- driven by fentanyl in counterfeit pills. The researchers also found 19 "hotspot" counties with particularly high overdose deaths.
Differences in blood flow in the retina could explain why some migraine patients experience visual symptoms while others do not, according to UCLA study.
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have received a five-year, $3 million grant from the National Cancer Institute to identify novel cancer biomarkers and develop AI that can detect and predict aggressive prostate cancer to help avoid unnecessary treatments and their associated negative side effects.
A new report by a UCLA neurologist and collaborators draws upon patient voices and lived experiences to identify the common pitfalls of Parkinson’s diagnoses and create a guidebook for how medical providers – from seasoned specialists to rural community physicians – can avoid them.
UCLA Health dementia care specialists say caregiving and holiday festivities do not have to be mutually exclusive, but do require some adaptations to make the season enjoyable for all.
The high-fat, low-carbohydrate ketogenic diet is more than just a trendy weight-loss tactic. It has also been known to help control seizures in children with epilepsy, particularly those who don’t respond to first-line anti-seizure medications.
Dr. Aditya Bardia, a renowned breast medical oncologist and physician scientist who specializes in developing novel targeted and personalized therapies, has joined the David Geffen School of Medicine at UCLA and the UCLA Health Jonsson Comprehensive Cancer Center where he will assume several leadership roles across the institution.
A new UCLA Health study is shedding light on how using hormonal contraceptive pills may affect women’s responses to stress and their risk for inflammation-related illnesses.
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center have received two grants totaling $9.1 million from the National Cancer Institute to advance liquid biopsy technologies for the early detection of cancer, which can significantly improve treatment outcomes and reduce the number of deaths caused by the disease.
Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow — advancements that can help explain why some prostate cancers become resistant to hormone therapy, the most commonly used treatment for men with advanced stages of the disease.
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found Black men diagnosed with more advanced stages of prostate cancer are significantly less likely to be prescribed novel hormone therapy than other racial and ethnic groups – including white or Latino men – despite the therapy being proven to effectively control the growth of prostate tumors and extend the lives of men with the disease.
A nearly decade-long study by UCLA researchers found that substance abuse treatment of any kind may help to reduce methamphetamine usage among men who have sex with other men.
Dr. Bryan Burt, an internationally recognized surgeon-scientist and surgical oncologist, has joined UCLA Health and the David Geffen School of Medicine at UCLA as the new chief of thoracic surgery and professor of surgery.
Researchers at the UCLA Jonsson Comprehensive Cancer Center have found certain immune cells can still fight cancer even when the cancer cells lack an important protein that the immune system relies on to help track down cancer cells.
New research finds female surgeons had slightly lower patient mortality than males for elective surgeries, but no gender difference for non-elective procedures.
A new study from UCLA Health researchers demonstrates that a novel treatment is effective in most patients with major depressive symptoms even after multiple failed courses of antidepressant medication.
Among the nation’s hospitals, those that serve high numbers of Black and Hispanic patients are far less likely to have advanced medical equipment and critical services that have been shown to boost the quality and effectiveness of cancer care, according to a study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.
Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.
New Jersey resident Andre LaPierre, 67, thought he had put cancer behind him. In 2019, he was diagnosed with prostate cancer and had, what he thought, a successful surgery to remove his cancerous prostate.
UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target in cholesterol treatment.
FINDINGS GPT-4 conversational artificial intelligence (AI) has the ability to diagnose and triage health conditions comparable to that provided by board certified physicians, and its performance does not vary by patient race and ethnicity. BACKGROUND While GPT-4, a conversational artificial intelligence, “learns” from information on the internet, the accuracy of this form of AI for diagnosis and triage, and whether AI’s recommendations include racial and ethnic biases possibly gleaned from that information, have not been investigated even as the technology’s use in health care settings has grown in recent years.
November marks Lung Cancer Awareness Month and UCLA Health lung cancer experts are working to spread the word about the importance of low-dose computed tomography (LDCT) of the chest. The annual scan is recommended for people with a long-term history of smoking, as well as other criteria, including age.
UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for “off-the-shelf” cell therapy to treat challenging cancers.
Researchers found that by restricting glucose in lung cancer cells, it caused the cells to lose their specialized features, making them more aggressive. This change was linked to alteration in certain molecules and how they modify DNA structure.
The National Institutes of Health (NIH) has granted $2.1 million to UCLA’s Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and the UCLA-CDU Center for AIDS Research (CFAR) to support four research projects and an implementation science consultation hub.
Two studies led by UCLA researchers offer new insights into the way neurons in the human brain represent time and space – the most basic ingredients of consciousness of human existence and the primary dimensions of experience that allow us to reconstruct the past and envision the future.
Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate, was found to significantly improve progression-free survival in patients with metastatic non-small cell lung cancer, an improvement that was primarily driven by patients with non-squamous tumors.
A study led by UCLA researchers found that the children of parents who experienced adverse childhood experiences (ACEs)– such as abuse, neglect, violence in the home, or loss of a parent – are at increased risk of arrests and convictions by young adulthood.
In a new case report, researchers at UCLA Health describe promising results using repetitive transcranial magnetic stimulation (rTMS) in the management of post-stroke cerebellar ataxia, a debilitating condition marked by impaired coordination and balance.
A new study is gathering extensive data about people with bipolar disorder to improve diagnosis and treatment of this mental health condition that affects 40 million people worldwide, according to the World Health Organization.
New findings from researchers at UCLA Health suggest that measuring changes in how pupils react to light could help predict recovery from depression and personalize transcranial magnetic stimulation (TMS) treatment of major depressive disorder.
Herceptin has saved millions of women’s lives by targeting cancer at its genetic roots. In this interview, Dr. Slamon talks about the paradigm-shifting approach to cancer treatment and how the discovery has opened up an entirely new area of research.
A UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, possibly leading to new therapies for heart disease and cardiac damage.
A team of investigators from the UCLA Jonsson Comprehensive Cancer Center and the UCLA School of Dentistry received a five-year $4.6 million grant from the National Cancer Institute to develop and improve liquid biopsy technologies for the early detection of lung cancer — the leading cause of cancer death in both men and women in the U.S.
UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new role for a protein called extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that can trigger cells to self-destruct.
The eight companies selected to participate in UCLA Health’s second TechQuity Accelerator – launched in September – are creating innovative health care tools and services in harmony with the program’s special attention to equitable access for vulnerable populations.
A UCLA-led team of researchers has found nerve pathways that supply brown adipose tissue (BAT), a type of tissue that releases chemical energy from fat metabolism as heat – a finding that could pave the way toward using it to treat obesity and related metabolic conditions.
Dr. Tanya Stoyanova, associate professor of molecular and medical pharmacology and urology at the David Geffen School of Medicine at UCLA, was awarded a $350,000 Idea Development Award from the Department of Defense.
People frequently exposed to racial or ethnic discrimination may be more susceptible to obesity and related health risks in part because of a stress response that changes biological processes and how we process food cues according to UCLA research.