The National Cancer Institute has awarded a four-year, more than $1.87 million grant to University of North Carolina Lineberger Comprehensive Cancer Center researchers to study the impact of implementing financial navigation services at five rural cancer centers in North Carolina to help patients cope with the financial burden, or financial toxicity, related to cancer care.
The National Cancer Institute has awarded a University of North Carolina Lineberger Comprehensive Cancer Center researcher a five-year, $2.7 million grant to develop more effective health warnings for little cigars and cigarillos.
In a study published in the journal Cancer Immunology Research, University of North Carolina Lineberger Comprehensive Cancer Center researchers reported on the discovery of a method for predicting whether abnormal proteins produced by cancer cells could trigger an immune response.
UNC Health Care leads the innovation of telehealth by developing a fully integrated solution that enables patients to easily access providers through enhanced functionality of their My UNC Chart patient portal. Partnering with American Well, UNC Health Care launched the Telehealth (clinical) app into its Epic electronic health record (EHR) workflow that now offers patients video visits and video consultations with one click.
Scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers used in PET imaging.
University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection.
The Center for Health Promotion and Disease Prevention (HPDP) at the University of North Carolina at Chapel Hill has received a five-year, $3.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) to fund research that will address the challenge of achieving long-term weight loss among patients with obesity cared for at primary care practices.
Researchers found just 15 percent of a group of men with early-stage prostate cancer received biopsies and other tests according to active surveillance guidelines from the National Comprehensive Cancer Network.
Findings published in the Journal of Clinical Oncology could help define strategies to more effectively treat colorectal cancer, the second leading cause of cancer death in the United States.
Findings published in Nature Medicine lead to clinical trials
The United States Agency for International Development, in partnership with the U.S. National Academies of Science, Engineering, and Medicine, will fund two new programs to prevent cervical cancer in sub-Saharan Africa, including a project led by UNC scientists and physicians in Malawi.
A collaborative group of researchers co-led by a UNC Lineberger Comprehensive Cancer Center scientist found that, in women 55 years and younger, breast cancer risk peaked about five years after they gave birth, with risk for mothers 80 percent higher compared with women who did not give birth.
At the 60th Annual American Society of Hematology Annual Meeting in San Diego on Monday, UNC Lineberger researchers revealed preliminary results from a clinical study of an investigational cellular immunotherapy for Hodgkin lymphoma and non-Hodgkin lymphoma expressing the CD30 protein marker.
In a study published in the journal NPJ Breast Cancer, researchers reported they used a form of artificial intelligence called machine learning, or deep learning, to train a computer to identify certain features of breast cancer tumors from images.
In the journal Obstetrics & Gynecology, researchers published the results of mailing at-home, HPV self-collection kits to 193 low-income women in North Carolina who were overdue for screening according to national guidelines.
Researchers will present preliminary findings at the 60th Annual Meeting of the American Society for Radiation Oncology in San Antonio on Tuesday, Oct. 23, from a study evaluated a blood test for HPV-linked oropharyngeal squamous cell carcinoma.
A UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient’s airway is inflamed. This is the first study to evaluate the efficacy of these drugs under inflammatory conditions relevant to CF airways.
A study led by University of North Carolina Lineberger Comprehensive Cancer Center researchers investigated the extent and severity of negative financial effects of cancer among women with breast cancer that has spread in the body. The preliminary results were presented at the American Society of Clinical Oncology’s Quality Care Symposium, held Sept. 28-29 in Phoenix.
UNC researchers led by Arlene Chung, MD, MHA, reviewed more than 300 apps in the health and fitness categories of app stores for hands-free, voice-activated assistants, including Amazon’s Alexa and Google Assistant; they found very few had a clear health focus.
A UNC Lineberger Comprehensive Cancer Center researcher and his colleagues have been awarded a five-year, $3.2 million grant from the National Cancer Institute to investigate how to improve radiation treatment for dogs undergoing treatment for sarcoma.
The NIH has given a $2.7 million R01 award to researchers at the University of North Carolina at Chapel Hill and their colleagues in Nicaragua to study maternal-fetal transmission of Zika and its impact on infant neurodevelopment.
A new study published in the Journal of the American Heart Association shows disparities between the care given to black and white patients seeking treatment for a type of heart attack called NSTEMI (Non-ST-elevation myocardial infarction).
A new study led by UNC School of Medicine researchers indicates that ozone has a greater impact on asthma patients than previously thought.
CHAPEL HILL, N.C. – Sept. 17, 2018 – In the aftermath of Hurricane Florence and continued challenging conditions across much of the state, UNC Health Care has extended its offer of free access to its virtual care service, UNC Urgent Care 24/7. Free access will be available for persons physically located in the State of North Carolina through Sunday, September 23rd at 11:59 pm.
Researchers examined the costs associated with screening for prostate cancer, including treatment, for three years after diagnosis. They estimated that for men diagnosed in each of 2004, 2005, 2006, and 2007, the total cost for treating and screening for each group would be $1.2 billion for three years after diagnosis.
Hurricane Florence victims in North Carolina can access medical care around-the-clock
Researchers from St. Jude Children’s Research Hospital and the University of North Carolina Lineberger Comprehensive Cancer Center have made important discoveries that could lead to better treatment for a rare blood cancer in children that has features of both acute myeloid leukemia and acute lymphoblastic leukemia.
The NIH has awarded the UNC HIV Cure Center and Cell Microsystems a Small Business Innovation and Research contract to develop an automated platform to quantify the latent HIV reservoir, a key step in finding a cure for the virus.
UNC researchers say the results from the multi-site phase 2 and 3 trials of brexanolone injection are not only promising, but could change the way postpartum depression is treated.
UNC Lineberger Comprehensive Cancer Center researchers showed they could shrink tumors in laboratory models of medulloblastoma. The study, published in PLOS ONE, is a necessary step toward developing clinical trials that would see if the approach works for children.
Researchers at the University of North Carolina at Chapel Hill have found that crowdsourced campaigns can motivated men at-risk of HIV infection in China to get tested.
Blue Cross and Blue Shield of North Carolina (Blue Cross NC) and UNC Health Care’s UNC Health Alliance announced today a partnership that reduces premium costs for Affordable Care Act (ACA) customers in the Triangle by more than $1,680 a year on average, before subsidies. The North Carolina Department of Insurance (NCDOI) today approved an average rate decrease of more than 21 percent for these customers.
Scientists discovered why some drugs activate serotonin receptor 5-HT2B to cause serious heart problems while other very similar drugs don’t. This research, led by UNC School of Medicine scientists, provides drug developers with insights that should help them create safer more effective drugs.
Researchers discovered a gene mutation underlying hydrops fetalis – a fatal condition to fetuses. The proteins at the center of this finding are implicated in a number of diseases, opening avenues of potential drug discovery related to migraines, diabetes, osteoporosis, and other conditions.
Although national guidelines advise doctors to discuss the benefits and harms of lung cancer screening with high-risk patients because of a high rate of false positives and other factors, those conversations aren’t happening the way they should be, according to a study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center.
A new systematic review provides the most comprehensive assessment to date on the scientific evidence estimating the effectiveness of various fertility awareness-based methods (FABMs) for contraception.
All living things use the genetic code to “translate” DNA-based genetic information into proteins. Precisely how the process of translation arose in the earliest stages of life on Earth has long been mysterious, but two theoretical biologists have now made a significant advance in this field.
A small population of brain cells called "mossy cells" deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.
In a study published in the journal Science, researchers suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.
Researchers with UNC Lineberger’s Carolina Cancer Screening Initiative, in collaboration with the Mecklenburg County Health Department in Charlotte, examined the impact of mailing tests to more than 2,100 people insured by Medicaid who were not up-to-date with colorectal cancer screening.
In late June, UNC Health Care became the first organization in North Carolina to integrate its Epic Electronic Health Record (EHR) system with the NC Controlled Substance Reporting System, a giant step forward in empowering the system’s physicians to address the opioid epidemic.
Researchers investigated whether the location of the mutation within the sequence of the PIK3CA gene affected the mutation’s ability to help drive glioblastoma growth. They also tested whether mutations within certain sequences of the gene were linked to better responses to particular drugs. They found mutational status was not linked to a response to a single targeted drug, but it was to a combination of treatments.
University of North Carolina School of Medicine researchers have discovered that a protein called Spt6 facilitates RNA degradation so that cells have just the right amount of RNA for the creation of proteins, a key component to human health and the avoidance of disease.
A study led by UNC’s Sylvia Becker-Dreps, MD, MPH, reviewed more than 675,000 pregnancies in the U.S. to determine if the Tdap vaccine given to a mother will reduce the chances of her child developing pertussis during the first 18 months of life. The results show a decrease in overall cases of pertussis, and most notably, in pertussis hospitalization in infants whose mothers were immunized during pregnancy.
Parents ranked cancer prevention as the most compelling reason health care providers can give for recommending the human papillomavirus (HPV) vaccine, according to a survey led by University of North Carolina Lineberger Comprehensive Cancer Center researchers.
The Chronic Pancreatitis and Autologous Islet Cell Transplant Program, created by Chirag S. Desai, MD, is helping patients improve their quality of life by eliminating severe pain and reducing or ending the use of narcotic pain medications, while preventing brittle diabetes.
In a collaborative, multi-institution effort to map the genetic and genomic changes in cancer, researchers led by UNC Lineberger's Katherine Hoadley, PhD, analyzed 137 testicular germ cell tumors for potential mutations and other molecular changes. They identified molecular features of testicular germ cell cancers that could inform future efforts to improve treatment decisions, and help monitor patients to see if their cancer has come back. Their findings were published in Cell Reports.
Heart defects are the most common type of birth defect, and can be caused by mutations in the gene CHD4. Researchers at the University of North Carolina School of Medicine have now revealed key molecular details of how CHD4 mutations lead to heart defects.
A study by UNC Lineberger Comprehensive Cancer Center's Ronald Chen, MD, MPH, and colleagues assessed whether monitoring prostate cancer patients following treatment with a PSA test every three months versus once a year would provide a long-term survival benefit.
The UNC AFib Care Network has launched a new clinic that coordinates all of the services needed by patients with atrial fibrillation (AFib) in one convenient location.
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