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Study results show pediatric patients with active Crohn’s disease and ulcerative colitis can reach remission with diet alone.

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Imagine conquering childhood cancer, only to find out that years down the road your heart may fail. Unfortunately, many children who have battled cancer face this reality. While often lifesaving, the effects of chemotherapy treatment (drugs that kill cancer cells) can take a toll on the developing body of a child, potentially resulting in life-threatening late side effects like cardiac damage.

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A new study in the Journal of Dental Research suggests that dental problems commonly associated with cleft lip and palate may be caused by abnormalities in salivary glands and an imbalance of immune compounds in the mouth.

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Sudden Infant Death Syndrome (SIDS) may be linked to the build up of carbon dioxide and existing inner ear damage according to a new study in the journal Neuroscience. Author Dr. Daniel Rubens, an anesthesiologist and researcher at Seattle Children’s Research Institute, says the finding could help researchers understand the sequence of events and risk factors that lead to SIDS deaths.

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In our digital age, it’s not uncommon to see a toddler on an iPad at the airport or a teenager at the mall fixated on a smartphone. To help families establish healthy habits for media use, the American Academy of Pediatrics (AAP) released new media and screen time policies for children. Co-authors of the policy, Drs. Megan Moreno and Dimitri Christakis of Seattle Children's Research Institute, share their insight.

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Shortly after Olivia Alva was born, doctors diagnosed her with biliary atresia, a rare disease of the liver that occurs in about 1 in every 15,000 babies. Olivia's mother, Patricia, became a living donor for her daughter by getting a portion of her liver removed to replace Olivia's diseased liver.

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A new $157 million initiative launched by the National Institutes of Health aims to create a comprehensive understanding of how chemicals and environmental factors like air pollution impact childhood development. Dr. Sheela Sathyanarayana, a pediatric environmental health researcher at Seattle Children’s Research Institute, was selected as one of the principle investigators whose focus is chemical exposures.

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Seattle Children’s Intensive Outpatient OCD Treatment Program is only one of six intensive programs in the country. Since the program opened in July 2016, it has seen tremendous success in treating patients like Eva Tomassini who was diagnosed with Obsessive-Compulsive Disorder (OCD) when she was 4 years old.

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Seattle Children’s Hospital has opened a new Gender Clinic for children, adolescents and young adults up to 21 years of age. The multidisciplinary clinic, which opened Oct. 4, 2016, offers services to youth whose gender does not match their sex at birth or who do not identify with traditional definitions of male or female.

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Dr. Lenna Liu, a pediatrician at Seattle Children’s explains mindful eating and give tips for how to create a warm, caring and supportive environment around food for your family.

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A team at Seattle Children’s Research Institute came up with an idea to make a life-changing moment feel a little more personal for patients undergoing immunotherapy. A teddy bear wearing a mask and purple cape, aptly named T-Bear, is given to patients as they receive their re-engineered T cells to help recognize and destroy their cancer.

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Hunter Coffman was diagnosed with a brain tumor at Seattle Children’s when he was 2-years-old. While preparing for the surgery to remove the tumor, Hunter’s parents were also presented with the opportunity to enroll Hunter in Seattle Children’s Phase 1 trial of BLZ-100 Tumor Paint, a drug that aims to improve surgical outcomes by acting as a molecular flashlight that allows surgeons to visibly distinguish a tumor from normal brain tissue. BLZ-100 Tumor Paint was invented by a team led by Dr. Jim Olson, pediatric neuro-oncologist at Seattle Children’s.

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Ever wonder what it’s like to walk in the ‘shoes’, or rather the ‘paw prints’, of a furry friend? Seattle Children's features one of the incredible canine and human companion pairs that bring joy and comfort to the hospital each week through their Visiting Dog Program.

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Researchers at Seattle Children’s Research Institute published a study in the journal Pediatrics showing a new intervention for adolescents with persistent post-concussive symptoms that improved health and wellness outcomes significantly. The approach combines cognitive behavioral therapy and coordinated care among providers, schools, patients and families.

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Depression can create a huge cost burden on patients and institutions, and for teenagers that includes issues like missed school and the costs of healthcare for families. A new study in JAMA Pediatrics, led by Seattle Children’s Research Institute and Group Health Cooperative, identifies a cost-effective treatment that yields promising results for depressed teens. “We used a collaborative care approach to treat teen depression, which included having a depression care manager who worked with the patient, family and doctors to develop a plan and support the teen in implementing that plan,” said Dr. Laura Richardson, an adolescent medicine physician and researcher at Seattle Children’s.

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Doctors and researchers know that man-made chemicals commonly found in plastics, foods, personal care products and building materials can interfere with how hormones like estrogen and testosterone work in the body.

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There are a couple strains of herpes so common that researchers estimate 90% of the human population have them. These strains, human herpes 6 and human herpes 7, usually do not cause severe symptoms when people acquire them. But researchers know that under certain circumstances, dormant herpes viruses in the body can unexpectedly come roaring back and cause complications not typically associated with herpes virus.

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Group B streptococcus (GBS) is the most common life-threatening bacterial infection in newborns worldwide. GBS typically resides in the lower genital tract but does not cause infections in healthy women. But if the infection is transmitted to an infant during pregnancy, it can lead to preterm birth or stillbirth. If the infection is transmitted to a newborn, it can cause pneumonia, sepsis or meningitis, all of which can occur within the first week of life or within 90 days of birth. The goal of my research is to prevent maternal to infant transmission of GBS.

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Summer is here and backyard barbecues, camping trips and youth camp sessions are in full swing. Amidst all of these fun activities is often a far less welcoming sign of summer: mosquitoes.

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A child with absence epilepsy may be in the middle of doing something—she could be dancing, studying, talking—when all of a sudden she stares off into space for a few moments. Then, as quickly as she drifted off, the child snaps back into whatever she was doing, unaware that the episode occurred.

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Subcranial rotation distraction is enabling children like Hannah Schow to breathe without a tracheostomy for the first time.

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Seattle Children’s is partnering on the launch of a study called the ‘Oto-Acoustic Signals in SIDS’ (OASIS) study that will investigate a possible association between Sudden Infant Death Syndrome (SIDS) and inner ear damage in newborns.

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The National Institutes of Health (NIH) has awarded $2 million to Seattle Children’s Research Institute to study a method that targets obesity using long-term interventions that provide children and parents with focused guidance and education to help them reach and sustain weight loss goals.

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Scientists at Seattle Children’s Research Institute have found a way to rapidly suppress epilepsy in mouse models by manipulating a known genetic pathway using a cancer drug currently in human clinical trials for the treatment of brain and breast cancer.

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Seattle Children's researchers discover method to prevent graft-versus-host disease, a dangerous and common complication of bone marrow transplants.

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Seattle Children’s, PATH and the University of Washington School of Dentistry announced today that they were recently nominated for a $250,000 validation award from Saving Lives at Birth: A Grand Challenge for Development – a partnership of the United States Agency for International Development (USAID), the Government of Norway, the Bill & Melinda Gates Foundation, Grand Challenges Canada, the U.K.’s Department for International Development (DFID), and the Korea International Cooperation Agency (KOICA) – to fund research and development of the Neonatal Intuitive Feeding TechnologY (NIFTY™ cup).

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A new collaboration between Seattle Children’s Research Institute and bluebird bio, Inc., a biotechnology company based in Cambridge, Massachusetts and Seattle, will allow researchers to develop potentially transformative gene therapies for severe genetic and rare diseases. The collaboration supports pediatric researchers in Seattle who will work with bluebird scientists and the company’s gene editing technology to research potential cures for genetic pediatric diseases.

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Results from clinical trials show that a new combination of medications can successfully treat the underlying cause of cystic fibrosis for patients 12 and older with two copies of the F508del gene mutation – the most common form of the life-threatening, genetic disease found in over half of the CF population.

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The Twitterbowl 2015 football and fundraising challenge, initiated by actors Chris Evans and Chris Pratt, has raised nearly $27,000 for Seattle Children’s and Christopher’s Haven since the contest was launched on Jan. 29.

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Preterm birth is the leading cause of death for children under 5 worldwide, and a new scientific paper reveals a startling lack of knowledge about what causes it and how to prevent it. Published in the November issue of Science Translational Medicine, “Prevention of Preterm Birth: Harnessing Science to Address the Global Epidemic” shines a light on the urgent need for a larger, coordinated research effort to discover how to identify women at risk of preterm birth and develop prevention interventions.

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Seattle Children’s today announced the opening of patient enrollment for its new cellular immunotherapy clinical research trial designed to induce remission in children suffering from neuroblastoma, one of the deadliest forms of childhood cancer.

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The U.S. Food and Drug Administration’s Office of Orphan Products Development has awarded Seattle Children’s Research Institute a $1.6 million grant to lead a 4-year, multi-site clinical trial aimed at improving long-term health in infants born with a heart defect.

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Scientists at Seattle Children’s Research Institute have discovered an area of the brain that could control a person’s motivation to exercise and participate in other rewarding activities – potentially leading to improved treatments for depression.

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The Global Coalition to Advance Preterm birth Research (GCAPR) is a partnership initiated by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the March of Dimes Foundation, the Bill & Melinda Gates Foundation, as well as the Global Alliance to Prevent Prematurity and Stillbirth, an initiative of Seattle Children’s. A total of 16 institutions are now members of the Coalition, which will advance needed research into the field of preterm birth, a blueprint of which was detailed in The Lancet Global Health in December 2013.

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HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children’s Research Institute, University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells. The study entitled “Center for Global Infectious Disease Research,” was published on July 10, 2014 in the online edition of the journal Science.

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A researcher at Seattle Children’s Hospital and Research Institute has found a genetic identifier for autism that includes physical features that may eventually allow clinicians to identify babies who are at risk for autism before they are born. This is the first time a genetic mutation has been linked to autism.

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Seattle Children’s Research Institute today announced that Tim Rose, PhD, co-director of the Center for Global Infectious Disease Research, in partnership with Micronics, Inc., a medical device development company in Redmond, Wash., has been awarded a $5.3 million five-year grant from the National Institute of Allergy and Infectious Diseases.

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Seattle Children's leukemia patient disease free after new cancer therapy.

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The Washington State Department of Health has designated the neonatal intensive care unit at Seattle Children’s Hospital as a Level IV regional NICU. Seattle Children’s is the first hospital in Washington state to receive this designation.

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Cancer and critical care patients move in April 21; emergency department opens April 23.

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International team finds genes associated with condition that causes premature skull fusion.

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• New surveys show research and funding is uncoordinated, lacking a cohesive agenda • Article in American Journal of Obstetrics and Gynecology provides strategic framework to save millions of lives.

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Five innovative research projects aiming to prevent premature birth were announced today by the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS), an initiative of Seattle Children’s.

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Funding Awarded to Seattle Children’s Hospital, Public Health - Seattle & King County and Healthy King County Coalition to Focus on Nutrition, Physical Activity and Tobacco Prevention in Partnership with Youth, Families and Communities.

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Leaders of prominent, international philanthropic and research organizations are convening in Seattle July 14-16 to address the global crisis of preterm birth and develop an action roadmap of research priorities and opportunities.

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Researchers shed light on molecular cause of childhood’s worst conditions as first step toward developing more effective treatments

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Access to science education increased for Washington State kids, families.

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Website may help curb healthcare costs, kids affected by chronic condition.

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Patients ages 13 to 24 given opioids for pain more than twice as likely to become addicted if they have mental health disorder, study finds.

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Children’s cancer, nephrology, urology and neurology/neurosurgery programs in nation’s top ten.