Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.
In an article published in Nature on October 14, 2020, scientists at Princess Margaret Cancer Centre, University of Toronto, Stanford University, Johns Hopkins, Harvard School of Public Health, Massachusetts Institute of Technology, and others, challenge scientific journals to hold computational researchers to higher standards of transparency, and call for their colleagues to share their code, models and computational environments in publications.
One in five Canadian adults is currently living with arthritis, a disease causing inflammation of the joints, which can result in chronic, debilitating pain, reduced mobility and premature disability. Arthritis is the leading cause of disability globally. To address this growing crisis, the Schroeder Arthritis Institute, launched with a $25 million donation by philanthropists Walter and Maria Schroeder, will help UHN’s innovative arthritis program become a world-class hub for innovation in research, education and patient care.
The Ted Rogers Centre for Heart Research, at the Peter Munk Cardiac Centre (University Health Network) are collaborating with Apple, Inc., to give heart failure patients even more control over their health, and usher in a new era of remote monitoring possibilities.
An international, first-of-its-kind cardiology trial used personalized genetic testing to reduce by 34 per cent the number of serious adverse events following balloon angioplasty, a treatment for the most common form of heart disease.
Taking advantage of a cancer cell’s altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.
A test which detects changing levels of tumour fragments in the blood may be an easy, non-invasive and quick way to predict who will benefit from immunotherapy, a treatment option for advanced cancers.
Medical cannabis is finally being put under the microscope, in a first-of-its-kind real world evidence study led by Dr. Hance Clarke, Toronto General Hospital. In the Medical Cannabis Real-World Evidence trial patients using the online portal created by Medical Cannabis by Shoppers, will know exactly what is in their product and its effectiveness.
Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.
Dr. Eugene Chang was 25, recently engaged and halfway through a physical medicine and rehabilitation residency in Vancouver when he started feeling sick. Fatigue, dizziness and nausea took over his normally active lifestyle. Suddenly his bike to work was not so easy.
The Silver Tsunami will see an unprecedented number of seniors in Canada. Thanks to a $3-million investment from The Slaight Family Foundation, University Health Network (UHN) is one step closer to being able to design programs and supports to enable seniors to live and thrive in their communities.
More than 1,900 participants, making up 167 teams, faced off today at Woodbine Racetrack in Toronto and raised a record-breaking $3.1 million as part of the 9th annual Scotiabank Road Hockey to Conquer Cancer. This brings the annual event’s nine-year fundraising total to over $23 million raised.
Canada’s largest-ever concussion study, led by researchers at Toronto Rehab, has uncovered rates that are nearly double what has previously been recorded, showcasing the need for increased education about concussion and access to more specialized, best-in-practice concussion care.
With a $10-million donation, the University of Toronto is partnering with Princess Margaret Cancer Centre to launch the McCain Centre for Urological Innovation and Education.
A first of its kind study is reporting that millions of women in low- and middle-income countries will need life-saving radiotherapy to treat their cervical cancer, despite the growth of essential human papilloma virus (HPV) vaccination prevention programs.
An anonymous living liver donor helped the UHN Transplant Program achieve a North American first with an innovative living liver donor exchange, or “swap,” that saved the lives of two failing liver patients, with the potential to save many more.
New research from the laboratory of cancer scientist Dr. Tak Mak, renowned for cloning the human T-cell receptor, has demonstrated that immune cells make brain chemicals to fight off infections.
Dr. Bradly Wouters, Executive Vice President, Science and Research – University Health Network (UHN) announced today the appointment of Aaron Schimmer MD, PhD, FRCPC to the position of Research Director at Princess Margaret Cancer Centre, UHN.
A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis - a common side effect of radiotherapy affecting quality of life of cancer survivors.
Scientists at the Peter Munk Cardiac Centre, at the University Health Network, have identified the type of cell key to helping the heart repair and potentially regenerate following a heart attack.
Patients who experience disturbances in sleep, mobility, nutrition or mood while admitted in hospital may be more likely to be readmitted within 30 days after discharge, finds a new study co-led by St. Michael’s Hospital and the University Health Network (UHN) in Canada.
Cancer scientists led by principal investigator Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have combined “liquid biopsy”, epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages.
Scientists led by Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have discovered a gene signature biomarker that may predict which patients will respond – or not – to immune therapy.
A new study out of the Krembil Brain Institute, part of the Krembil Research Institute, suggests drinking coffee may protect you against developing both Alzheimer’s and Parkinson’s disease.
A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.
Declared “Officially Amazing” by Guinness World Record adjudicator Michael Empric last year, Rocket Ride for Rehab is returning to Nathan Phillips Square this Saturday, October 13th in support of Toronto Rehab Foundation.
A research team at the Krembil Research Institute in Toronto has developed an innovative strategy that could help to restore breathing following traumatic spinal cord injury.
Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks.
Media are invited to attend The Princess Margaret Cancer Foundation’s (PMCF) annual launch of their BREASTOBER program.
On September 29th, hockey legends, media personalities and passionate players will unite at the 8th annual Scotiabank Road Hockey to Conquer Cancer to defeat their toughest opponent yet.
In a remarkable new genetic discovery, researchers at the Peter Munk Cardiac Centre, University Health Network (UHN), Ted Rogers Centre for Heart Research and The Hospital for Sick Children (SickKids) have found strong evidence that rare DNA variations can lead to Tetralogy of Fallot (ToF).
An Ontario clinical study that shows adding PET imaging to conventional CT imaging to stage locally advanced cervix cancer can change treatment means newly diagnosed women in this province may also receive PET imaging.
The Princess Margaret Cancer Foundation announced today that Meaghan Stovel McKnight has been appointed Chief Operating Officer, a new position within the Foundation.
A study led by researchers at the Peter Munk Cardiac Centre (PMCC) at UHN suggests that the model used by the Canadian Institute for Health Information (CIHI) significantly underestimates mortality in specialized heart surgery centres. The findings show that CIHI's model does not capture all of the medical problems that patients at high risk for surgery have.
The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute (TGHRI) scientists.
A unique pain program is helping complex surgical patients wean off opioids safely and effectively, while offering alternative ways to cope with their pain and improve how they function.
An international team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia (AML), an aggressive and often deadly blood cancer.
A new study published in Circulation, a peer-reviewed journal of the American Heart Association and led by a cardiologist at the Peter Munk Cardiac Centre at Toronto General Hospital has found evidence that only one of the 21 genes normally associated with Brugada Syndrome is a definitive cause of the condition.
An age group analysis of data from the ADvance trial has shown that participants over the age of 65 continue to derive the most benefit from Deep Brain Stimulation of the fornix (DBS-f), as observed in the data from the phase 2 findings (12 – 24 months) of the Phase II trial.
Donor lungs from individuals infected with hepatitis C have been successfully transplanted into 10 patients at Toronto General Hospital (TG), University Health Network (UHN).
Dr. Davis has shown that individuals can be classified as one of two types depending on how pain affects their performance in doing a task. In P-type individuals, pain impedes their ability to perform a task; whereas, in A-type individuals, like Bobby Baun, pain enhances their performance.
Three Olympians and a pioneer in women’s hockey announce today that they are donating their brains to the Canadian Concussion Centre (CCC) to advance research on the effects of concussion in women.
Select adult patients born with a single functioning ventricle (pumping chamber of the heart), and who have undergone a surgical operation called the ‘Fontan procedure’ during childhood, are now being enrolled in a global first clinical trial, led by a multi-disciplinary team of heart and lung physicians, to examine the effects of a portable, non-invasive medical device never before tested on patients with this cardiac condition.
The Princess Margaret Cancer Foundation announces the launch of Colour Your Hair to Conquer Cancer, a bold and engaging new fundraising initiative benefiting the Princess Margaret Cancer Centre.
The Ted Rogers Centre for Heart Research today announces that Dr. Slava Epelman has accepted the brand new role of Loretta Rogers Chair in Immunobioengineering.
The Princess Margaret Cancer Foundation will announce the launch of Colour Your Hair to Conquer Cancer presented by Trade Secrets.
Mr. Peter Munk has been one of the hospital’s most influential and loyal supporters for many years, serving on the Board of Trustees of the hospital, acting as an advisor to many of the hospital’s leaders, and supporting the creation, evolution and growth of the Peter Munk Cardiac Centre.
Mr. Brian Porter, Chair of the Board of Trustees of University Health Network (UHN) today announced that Kevin Smith, DPhil. is UHN’s incoming President & CEO.
A simple dietary supplement (L-arginine) was found to improve birth outcomes, paving the way for future clinical trials to test this inexpensive and safe intervention.
UHN now largest adult transplant program in North America. University Health Network’s Multi-Organ Transplant Program reached a milestone of completing 639 adult transplants in 2017, ranking first in volume for adult transplants in North America.
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