A new study from UH Harrington Heart & Vascular Institute in Cleveland further proves that people living in areas that were subjected to housing discrimination decades ago now suffer from higher rates of poor health outcomes, including heart disease, kidney failure and diabetes.
Spicy foods are trending lately, with a booming hot sauce market and spicy food challenges happening across the world and our devices. From TikTok pepper-eating contests to “extreme” items on restaurant menus that require adventurous diners to sign liability waivers, it begs the question: Can consuming the spiciest peppers and hot sauces in the world be bad for your health? University Hospitals dietitian, Jayna Metalonis, MS, RD, LD, explores this hot topic and shares the surprising health benefits of spicy foods.
Cleveland's University Hospitals patients with strokes are being given tenecteplase, a faster-acting drug than alteplase (tPA), which has been a mainstay since the 1990s.
Announcement of renowned neurosurgeon Sepideh Amin-Hanjani, MD, joining University Hospitals Cleveland Medical Center as the new Director, Cerebrovascular and Skull Base Surgery. She also is Vice-Chair of the Department of Neurological Surgery at UH.
Researchers at UH Rainbow published new findings that COVID-19 is not equivalent to flu infection for children. Among 66 pediatric ICUs in the US, the number admitted each quarter with COVID-19 or MIS-C during the first 15 months of the pandemic was twice as high as that for flu pre-pandemic.
Harrington Discovery Institute® at University Hospitals in Cleveland, Ohio, and its registered UK charity Fund for Cures UK, Ltd. (Fund for Cures UK) have issued a call for proposals for the 2023 Harrington UK Rare Disease Scholar Award. In addition to grant funding, Harrington Discovery provides guidance and oversight in drug development, while intellectual property is retained by the scholar and their institution.
A drug currently used in just 1% of cancers has significant potential against the remaining 99%, according to a new study from UH Seidman Cancer Center and Case Western Reserve University, published in the prestigious journal Nature Cancer. Ivosidenib, or AG-120, is currently used against cancers that have a mutation in the IDH1 gene. However, study results show that Ivosidenib is also effective against unmutated, or “wild-type” IDH1. The protein coded by the IDH1 gene in cancers helps cancer cells survive in a stressful tumor environment, so any inhibitor medication that could weaken this defense mechanism is considered a promising therapy. UH and CWRU scientists discovered that under conditions present in the tumor microenvironment, drugs previously believed to be selective for the mutant enzyme have activity against the normal protein. Specifically, low glucose and magnesium levels enhance drug activity. The team has now tested Ivosidenib in mouse models of pancreatic, colorectal, o
Harrington Discovery Institute at University Hospitals and the Alzheimer's Drug Discovery Foundation (ADDF) announce a joint request for proposals for the 2022 ADDF-Harrington Scholar Award. The ADDF-Harrington Scholar Award is designed to accelerate the translation of innovative research that could treat, prevent, or slow Alzheimer's disease or related dementias. The Request for Proposal (RFP) is open to academic investigators at accredited medical centers, research institutions, and universities in the United States, Canada, and the United Kingdom. Researchers working on drug development programs that are relevant to, but not presently focused on, the Alzheimer’s field are also encouraged to apply. This award provides a combination of financial support and expert drug development guidance to provide the best chance to move research beyond the bench to the bedside.
Announcement of Koen van Besien, MD, PhD, being named leader of the new Wesley Center for Immunotherapy at University Hospitals Seidman Cancer Center in Cleveland, Ohio. He also will head the Division of Hematology.
University Hospitals opened a fourth Food for Life Market location at UH Conneaut Medical Center. The program will set patients up for success in nutrition and dietary education. The Market is part of a holistic approach to addressing food insecurity and the medical conditions, including chronic health conditions, that are impacted by nutrition and access to healthy food in rural areas and food deserts.
University Hospitals (UH) Connor Whole Health and Susan Samueli Integrative Health Institute (SSIHI) at University of California, Irvine have joined in collaboration to lead BraveNet -- the first and largest whole health, practice-based research network in the U.S.
An innovative program at University Hospitals is yielding notable results, creating shorter hospital stays, less use of opioids, fewer post-surgical infections and lower costs for patients. Enhanced Recovery After Surgery (ERAS) recently won the Patient Engagement Best Practice Award from the Ohio Patient Safety Institute for 2021.
University Hospitals’ Jonathan Shoag, MD, and a team of researchers from Case Western Reserve University and the Case Comprehensive Cancer Center, Weill Cornell Medical Center, the Fred Hutchinson Cancer Research Center, and others, set out to assess the tradeoffs of PSA screening using long-term epidemiologic data. “No matter the assumptions,” Shoag said, “the data showed lower numbers than prior estimates, many in the low single digits, for the number needed to treat to prevent a prostate-cancer death. This result was observed in all men, and especially for Black men.” The researchers presented their findings in a late-breaking abstract at the American Urological Association’s annual meeting this month and the study was published May 15 in The New England Journal of Medicine Evidence.
Following an extensive search, Robyn Strosaker, MD, FAAP, has been named President and Chief Operating Officer of University Hospitals (UH) Lake West, TriPoint and Beachwood Medical Centers. She will begin her new appointment June 1, 2022.
Relief™ Stent, a new urinary stent invented by Lee Ponsky, MD, in collaboration with Dean Secrest, secured FDA 510k clearance, which means it can be marketed in the U.S. for patients suffering from kidney stones and other issues causing difficulty with drainage of the kidney.
Harrington Discovery Institute at University Hospitals in Cleveland, Ohio, today announced the 2022 class of Harrington Scholar-Innovators. The scholar awards will support a diverse set of drug discovery projects including new treatments for pulmonary diseases, COVID-19, multiple cancers, corneal disease, hepatitis, and acquired spinal cord injuries.
University Hospitals (UH) is unveiling a new partnership with Unite Us, an organization that enables UH to better connect patients to the services they need. By working together, UH and Unite Us are able to securely connect UH patients in need with community-based resources that can be difficult to navigate. Patients benefit from a secure, central point of contact where health care providers, social service organizations, and individuals can access and refer people to needed services while monitoring progress and measuring outcomes.
Metabolic syndrome increases a person’s risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar. In a recent mouse-model study, published in Cell Metabolism, researchers at University Hospitals (UH), Harrington Discovery Institute at UH, and Case Western Reserve University have furthered their progress to develop a drug to treat metabolic syndrome by identifying a receptor that controls appetite and body weight.
Announcement of Stathis Antoniades, MPH, FABC, appointed as President of UH Cleveland Medical Center.
The ninth annual Harrington Prize for Innovation in Medicine has been jointly awarded to James E. Crowe, Jr., MD, Director, Vanderbilt Vaccine Center and Professor, Departments of Pediatrics and Pathology, Microbiology and Immunology, Vanderbilt School of Medicine, and Michel C. Nussenzweig, MD, PhD, Investigator, HHMI, and Zanvil A. Cohn and Ralph M. Steinman Professor, The Rockefeller University. The award recognizes their groundbreaking work, which has elucidated fundamental principles of the human immune response and enabled the use of human antibodies to treat COVID-19.
A new study, completed by researchers at University Hospitals Harrington Heart & Vascular Institute, found people living in socially-deprived areas of the United States are more likely to die prematurely from cardiovascular complications.
University Hospitals in Cleveland has been recognized by Ethisphere, a global leader in defining and advancing the standards of ethical business practices, as one of the 2022 World’s Most Ethical Companies. This is the tenth year University Hospitals has received this recognition and is one of only seven honorees in the health care providers’ category. In 2022, 136 honorees were recognized spanning 22 countries and 45 industries.
The NFL Physicians Society's mission is to provide excellence in the medical and surgical care to the athletes in the NFL and to provide direction and support for the athletic trainers in charge of the care for these athletes.
University Hospitals is the first health system in Greater Cleveland to add the Mazor X Stealth™ Edition Robotic Guidance Platform to its regional spinal surgery program. Acquiring the Mazor X Stealth™ Edition Surgical Robotic Guidance is part of a continuous commitment to delivering the highest quality care for patients, ensuring that they receive the best treatment possible.
In an opinion article appearing online Feb. 25 in the Journal of the American Medical Association, authors from University Hospitals and Case Western Reserve University write about the unexpected patient safety benefit resulting from remote monitoring of patients during the COVID-19 pandemic. One of the major lessons gained from the pandemic was that patients could now be monitored based on risks and needs rather than location in the hospital. Home monitoring and hospital at-home models offer the potential to transform care and potentially allow a substantial proportion of hospitalized patients to receive care from home.
Harrington Discovery Institute at University Hospitals is now accepting Letters of Intent for the 2023 Harrington Scholar-Innovator Award for physician-scientists. The award offers successful applicants financial resources and expertise to advance their discoveries toward clinical trials. Intellectual property rights are retained by the award recipient or their institution.
A $2.5 million gift from Jane Meyer of Hunting Valley, Ohio, has established the Jane and Henry Meyer Chief Executive Officer Distinguished Chair at University Hospitals (UH) in celebration of the Meyer family’s legacy of leadership and service to the health system. Jane is joined in dedicating this endowed position in memory of her late husband, Henry L. Meyer III, by their three sons, Patrick, Andrew, and Christopher. In commemoration of his first anniversary as CEO of University Hospitals, Cliff A. Megerian, MD, FACS, has been named the inaugural Meyer Distinguished Chair.
A new study from University Hospitals Connor Whole Health found patients with Sickle Cell Disease who participated in music therapy learned new self-management skills and improved their ability to cope with pain.
University Hospitals Cleveland Medical Center and UH Rainbow Babies and Children’s Hospital are participating in a Cochlear Americas’-sponsored clinical trial for an implantable hearing device in children 5 to 11 years of age who have been born with hearing loss that may be caused by craniofacial abnormalities. UH was the first site in the nation to kick off the trial.
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Researchers at University Hospitals Seidman Cancer Center and Case Western Reserve University have developed a novel approach to chimeric antigen receptor (CAR) T-cell therapy for B-cell cancers that triples the targeted antigens on cancer cells – a “back up” approach that promises to greatly reduce the potential for antigen escape currently found in CAR T therapies that solely target CD19.
Findings from a first-of-its-kind study conducted at University Hospitals Harrington Heart & Vascular Institute showed a novel system-wide interdisciplinary team assembled to evaluate alternative treatments to major amputation improved outcomes for patients with Critical Limb-Threatening Ischemia.
Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is one of the common forms of treatment. In a first-of-its kind meta-analysis, published today in The Lancet Oncology, researchers from University Hospitals (UH) and Case Western Reserve University show that there is consistent improvement in overall survival in men with intermediate- and high-risk prostate cancer with the addition of hormone therapy to radiotherapy treatments.
In its first investment as part of its new Community Health Investment Strategy, University Hospitals is committing a total of $1.2 million to the Lead Safe Cleveland Coalition, a public-private partnership formed to address and prevent the pernicious issue of lead poisoning. As part of this new strategy, UH will take a portion of assets that would traditionally have been invested in such vehicles as stocks and bonds and make them available for investments into the under-resourced parts of Cleveland.
The Healthy Business Council of Ohio (HBCO) has recognized UH for demonstrating a commitment to employee well-being through comprehensive worksite health promotion and well-being programs, bestowing its Healthy Worksite Gold Award.
University Hospitals Cleveland Medical Center has announced the appointment of Nicholas C. Bambakidis, MD, as Chair of the Department of Neurosurgery, effective Jan. 1, 2022. He has served as Vice President and Director of the UH Neurological Institute since 2016, roles he will continue.
A team of interventional cardiologists and cardiac surgeons at UH Harrington Heart & Vascular Institute are the first in the U.S. to report a safer, minimally invasive strategy for removing infections in the heart associated with right-sided infective endocarditis.
In a new review article, published today in The New England Journal of Medicine, researchers from University Hospitals (UH), Case Western Reserve University and Boston College discuss evidence linking pollution and cardiovascular disease. The research team highlights strategies for reducing individual exposure to pollution, and the importance of government-supported interventions encouraging clean energy.
A commentary, published in the Nov. 3 issue of the journal NEJM Catalyst Innovations in Care Delivery, highlights how defects in surgical care could be diminished or eliminated for the benefit of patients and to lower costs in American health care spending. Using colorectal surgery to provide examples and national estimates of the costs of defects in surgical care, the paper summarizes a holistic approach to eliminating defects in surgical care and offers a framework for centers of excellence for removing them. The paper estimates that defects in colorectal surgery cost the American health care system more than $12 billion. The authors discuss eight areas (or domains) of defects that waste money and/or contribute to lower value in care for colorectal surgery patients.
Harrington Discovery Institute at University Hospitals and Case Western Reserve University School of Medicine have issued a call for proposals for the 2022 Harrington-MSTP (Medical Scientist Training Program) Scholar Award to help the next generation of physician-scientists advance their discoveries towards clinical application.
Lucid Diagnostics Inc., a company that produces esophageal cancer tests based on Case Western Reserve University and University Hospitals research, has completed a $70 million initial public offering (IPO) on the Nasdaq Global Market; at the IPO price, the company’s estimated value would be $467 million.
Several hospitals in the University Hospitals (UH) system have been recognized by the American Heart Association/American Stroke Association’s Get With The Guidelines®-Stroke Quality Achievement Awards for their quality stroke care. Get With The Guidelines®-Stroke awards were developed to help healthcare professionals provide the most up-to-date, research-based guidelines for treating stroke patients.
Vicki Noble, MD, has been named Chair, Department of Emergency Medicine at University Hospitals Cleveland Medical Center, and Emergency Medicine Physician-in-Chief for the UH health system.
In their paper, published Aug. 24 in the Frontiers of Nutrition, Dr. Mahmoud Ghannoum and colleagues from CWRU, UH Cleveland Medical Center, BIOHM Health, and Louis Stokes Cleveland VA Medical Center, examined current literature about the microbiome and gut-brain axis to advance a potential complementary approach to address depression and depressive disorders that have increased during the COVID-19 pandemic.
Metabolic syndrome is a cluster of conditions and includes obesity, and can be dangerous as it increases the risk for heart disease, stroke, diabetes and other diseases.
A clinical trial found liraglutide, an injectable weight loss medication, reduced intra-abdominal and liver fat in participants more than placebo in addition to a low-calorie diet and increased physical activity.
A University Hospitals (UH) patient is the first in Northeast Ohio to undergo a new, innovative procedure called CCM® therapy.
At its Summer Summit 2021 on June 15, Plug and Play gave University Hospitals Ventures – the innovation and commercialization arm of University Hospitals Health System -- the Health Corporate Innovation Award for its demonstrated commitment to expanding its innovation culture.
The UH Vaccine Playbook serves as a guide for those who are not yet “vaccine ready.”
A new innovation that holds promise to fight lung cancer is now in use at University Hospitals Cleveland Medical Center.
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