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Immunologists have uncovered new approaches to enhance protection from tumors and infections.

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UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science researchers investigated the associations of weight changes later in life with exceptional longevity and found that women who maintained their body weight after age 60 were more likely to reach exceptional longevity.

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Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

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New results from researchers at UC San Diego School of Medicine suggest that intermittent fasting could be an effective treatment approach for Alzheimer’s disease.

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While U.S. inflation has come down significantly from nearly 9% to 3% and unemployment continues to stay low, it will be challenging for the Federal Reserve to reduce inflation to its target of 2% without significantly raising the unemployment rate and possibly sinking the U.S. into a recession, according to a new working paper from the University of California of San Diego’s Rady School of Management.

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An international team of researchers led by UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science investigated the health and environmental impacts of a program in Ecuador that put induction stoves in 750,000 households.

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Creating new technologically advanced sensors, scientists from UC San Diego and Australia have engineered bacteria that detect the presence of tumor DNA in live organisms. Their innovation could pave the way to new biosensors capable of identifying various infections, cancers and other diseases.

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Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.

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New research from Q-MEEN-C shows that electrical stimuli passed between neighboring electrodes can also affect non-neighboring electrodes. Known as non-locality, this discovery is a crucial milestone toward creating brain-like computers with minimal energy requirements.

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Road safety is a critical issue in an era of increasing cannabis legalization. Cannabis is known to impair reaction time, decision-making, coordination and perception—skills necessary for safe driving. In the last three years, California has seen a 62% increase in the number of fatal crashes involving drug-related impairment.

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UC San Diego scientists debut Greengenes2, a massive reference database that could be used to reconcile years of microbiome studies.

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While composting and organic waste ban policies are gaining popularity across the United States, a new study from the University of California San Diego’s Rady School of Management finds dynamic pricing could be the most effective way for grocery chains to keep perishables out of landfills, reducing food waste by 21% or more.

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Researchers have created a resource for analyzing how viruses infect human cells. The fruit fly-based toolkit provides a shortcut for assessing SARS-CoV-2 genes and understanding how they interact with human proteins, offering researchers a resource for new COVID-related drug therapies.

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Superconductors - found in MRI machines, nuclear fusion reactors and magnetic-levitation trains - work by conducting electricity with no resistance at temperatures near absolute zero, or -459.67F. The search for a conventional superconductor that can function at room temperature has been ongoing for roughly a century, but research has sped up dramatically in the last decade because of new advances in machine learning (ML) using supercomputers such as Expanse at the San Diego Supercomputer Center (SDSC) at UC San Diego.

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UC San Diego scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria.

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A gift of $1.5 million from Eugene Jhong will help launch a new research program within the UC San Diego Psychedelic and Health Research Initiative to learn more about the biological and psychological effects of DMT in humans.

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Plant and animal stem cells both rely on the cytoskeleton to divide properly, but a new study finds that they use them in opposite ways—while animal cells pull on the cytoskeleton, plant cells push it away. Harnessing that action could help scientists engineer more resilient plants.

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Using CRISPR technology, scientists have engineered a new way to genetically suppress populations of Anopheles gambiae, the mosquitoes that primarily spread malaria in Africa and contribute to economic poverty in affected regions.

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Can you tell if what you’re reading right now was written by a human or generated by artificial intelligence? Do you care? Those are essentially the questions that University of California San Diego researchers asked in an experiment with ChatGPT at a regional high school.

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In a first of its kind comparison, UC San Diego scientists have shown that pollination by honey bees, which are not native to the Americas, produces offspring of considerably inferior quality (lower fitness) than offspring resulting from native pollinators.

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UC San Diego researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial.

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Adults who live in walkable neighborhoods are more likely to socialize and have a stronger sense of community, report researchers at the UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science.

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UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.

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Biologists have identified a previously unknown way that our immune system detects viruses. The immune protein CARD8 acts as a trip wire to detect a range of viruses, including the virus that causes COVID. They also found that CARD8 functions differently among species and varies between humans.

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Working with live squid hatchlings at Scripps Institution of Oceanography, UC San Diego scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.

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Researchers at UC San Diego have spent many years developing a biodegradable plastic alternative made from algae. This algae-based polymer has already been used to make surfboards, flip flops and walking shoes. A new book, published by Elsevier, details the basic science of creating bio-based polymers, lifecycle assessments and a techno-economic analysis.

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Applying imaging technology to plant roots, researchers have developed a new understanding of chemicals that are responsible for plant growth. The chemical “roadmap” identifies where key molecules are distributed along corn roots and how their placement factors into the plant’s maturation.

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A $2.5 million initiative supported by philanthropists Irwin and Joan Jacobs has created the Stuart and Barbara L. Brody Endowed Chair in Circadian Biology and Medicine, along with a supporting research fund, to target largely unexplored areas related to circadian biology and patient health.

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The University of California San Diego has been named No. 7 among U.S. public universities in the latest Center for World University Rankings (CWUR), rising one spot from the previous year.

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If viewers sometimes feel guilty about binge-watching television programing, they really shouldn’t. Though its name implies impulsive behavior, binge-watching TV is a common activity planned out by viewers, suggests new research from the University of California San Diego’s Rady School of Management and School of Global Policy and Strategy.

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The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.

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UC San Diego scientists develop an interactive software that enables scientists to better investigate the DNA damage response.

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Biologists have used machine learning, a type of AI, to identify “synthetic extreme” DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and found synthetic DNA sequences with activities that could be useful in biotechnology and medicine.

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In medicine and science, the term “pathogenesis” describes the origin and development of disease. There is not, however, a broadly accepted term to describe the other half of the equation: the process of healing and recovery.

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UC San Diego scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.

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Genome editing is used to modify the genes of living organisms to elicit certain traits, such as climate-resilient crops or treating human disease at the genetic level. It has become increasingly popular in agriculture, medicine and basic science research over the past decade, and will continue to be relevant and utilized well into the future.

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UC San Diego researchers describe how exposure to ambient air pollution, such as car exhaust and power plant emissions — is associated with a measurably greater risk of developing dementia over time.

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Jesse Driscoll, associate professor of political science at the UC San Diego School of Global Policy and Strategy, has authored a new book, “Ukraine's Unnamed War.” Driscoll traveled to Ukraine to begin researching the book in 2014. In this Q&A and video, Driscoll discusses how the current conflict emerged from the ragged settlement of 2014-2016 and shares insights on what to expect as the largest war in recent European history grinds forward.

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Researchers have developed a biosynthetic “clock” that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.

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Global space for Asian elephant habitats has been in rapid decline since the 1700s, a new report reveals. More than 3 million square kilometers of the Asian elephant’s historic habitat range has been lost in just three centuries and may underlie present-day conflicts between elephants and people.

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Graduate programs and professional schools at the University of California San Diego have once again been recognized for their excellence by U.S. News & World Report. The 2023-2024 Best Graduate Schools rankings, released today, named nine of the campus's graduate programs among the top 10 in the nation.

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UC San Diego researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little.

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Victor C. Shih has been appointed as the new director of the 21st Century China Center at the University of California San Diego School of Global Policy and Strategy, effective July 1, 2023. Shih, the Ho Miu Lam Chair in China and Pacific Relations at the School of Global Policy and Strategy, is a highly regarded scholar with expertise in a broad range of subjects related to China.

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Research led by UC San Diego and Harvard has traced the evolutionary adaptations of octopus and squid sensing capabilities. The researchers describe for the first time the structure of an octopus chemotactile receptor, which octopus arms use for taste-by-touch exploration of the seafloor.

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UC San Diego Researchers describe for the first time how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body’s ability to suppress it.

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Scientists have traced the origin of a unique protein key to vertebrate’s camera-like vision back 500 million years. Their analysis of more than 900 genomes across the tree of life revealed that the protein came through horizontal gene transfer from foreign bacterial genes.