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Juan Robles, M.D., attending physician at Montefiore Health System and assistant professor of family and social medicine at Albert Einstein College of Medicine, has earned a $1 million grant from the Health Resources and Services Administration (HRSA) to support Bronx students pursuing healthcare careers and create a more inclusive workforce dedicated to underserved communities.

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In a study in today’s issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate. Their earlier research—which first implicated nerves in fueling prostate cancer—has prompted Montefiore-Einstein to conduct a pilot study testing whether beta blockers (commonly used for treating hypertension) can kill cancer cells in tumors of men diagnosed with prostate cancer.

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Scientists now believe that the Fountain of Youth flows from our genes, or at least from the genes of people who live healthy lives to age 100 or later. To discover what’s special about the genes of centenarians—and apply that knowledge to extend the healthy lives of the rest of us—the NIH has awarded researchers at Albert Einstein College of Medicine and The Scripps Research Institute (TSRI) a five-year, $9 million grant.

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Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells. The new treatment approach, described in today’s issue of Cancer Cell, was directed against acute myeloid leukemia (AML) cells but may also have potential for attacking other types of cancers.

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The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses—Ebola, Marburg and hantavirus. Research collaborations between Kartik Chandran, Ph.D., professor of microbiology & immunology and the Harold and Muriel Block Faculty Scholar in Virology, and Jonathan Lai, Ph.D., associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments.

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The National Institutes of Health (NIH) has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $3.8 million grant for the first long-term study to test whether medical marijuana reduces opioid use among adults with chronic pain, including those with HIV.

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Scientists at Albert Einstein College of Medicine have found that stem cells in the brain’s hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan. The paper was published online today in Nature.

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The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine, The Rockefeller University, The City University of New York Graduate School of Public Health and Health Policy (CUNY), a $7.5 million grant for the Center for AIDS Research focused on preventing HIV transmission and ending the AIDS epidemic.

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After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses. The findings, published online today in the journal Cell, could lead to the first broadly effective ebolavirus therapies and vaccines.

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Global health leader and former Centers for Disease Control and Prevention (CDC) Director Tom Frieden, M.D., M.P.H., will deliver the keynote address at the 2017 commencement ceremony for Albert Einstein College of Medicine. Dr. Frieden, who also led the New York City Department of Health and Mental Hygiene, has worked to combat tuberculosis, Ebola, and Zika, reduce tobacco use, and protect and improve health in the United States and around the world. Einstein’s 59th graduation ceremony will be held Wednesday, May 23 at 3 p.m. at Lincoln Center’s David Geffen Hall.

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On Monday, April 24, the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine will host its third Stem Cell Symposium, focusing on the importance of cell metabolism and epigenetics. Leading scientists from the U.S., Japan and Germany will present their latest research and describe the hurdles to translating new finding into therapeutics.

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Frequent soccer ball heading is a common and under recognized cause of concussion symptoms, according to a study of amateur players led by Albert Einstein College of Medicine researchers. The findings run counter to earlier soccer studies suggesting concussion injuries mainly result from inadvertent head impacts, such as collisions with other players or a goalpost. The study was published online today in Neurology®, the medical journal of the American Academy of Neurology.

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An international consortium of academic research institutions have been awarded a $21 million grant from the National Institutes of Health (NIH) to develop better ways to prevent epilepsy in patients who have suffered traumatic brain injuries.

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Investigators at Albert Einstein College of Medicine were awarded more than $160 million from the National Institutes of Health in federal fiscal year 2016. The grants provide critical support for major research projects in aging, intellectual and developmental disabilities, diabetes, cancer and infectious diseases. Other key areas for which Einstein received federal support include developmental brain research, neuroscience, advanced cellular imaging, cardiac disease and initiatives to reduce health disparities.

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The National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine a five-year, $6 million grant to fund the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (IDDRC). The grant will also support a new research program focused on 22q11.2 Deletion Syndrome (22q11.2DS), an incurable genetic disorder associated with delayed intellectual development and psychiatric conditions, and some forms of congenital heart disease as well as other medical problems.

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The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $2.9-million grant to launch a new center, one of only 8 in the country, for diabetes translation research. The center—the New York Regional Center for Diabetes Translation Research (NY Regional CDTR)—also includes faculty from the Icahn School of Medicine at Mt. Sinai and the New York Academy of Medicine.

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Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence. Now, researchers at Albert Einstein College of Medicine have found that measuring the brain activity of healthy older adults while they’re walking and talking can predict their risk of falling. Their research is published today in the online issue of Neurology®, the medical journal of the American Academy of Neurology.

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December 1, 2016 — (BRONX, NY) —The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Pennsylvania State University a five-year, $12.2 million grant to continue studies on the aging brain, Alzheimer’s disease and other dementias. More than five million Americans are living with Alzheimer’s disease—a number that is expected to double by 2040 as baby boomers age.

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The National Institutes of Health (NIH) has awarded Bernice Morrow, Ph.D., at Albert Einstein College of Medicine and collaborators at the Children’s Hospital of Philadelphia (CHOP) a five-year, $7.5 million grant to study the genetics of congenital heart abnormalities.

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Researchers, led by Steven Almo, Ph.D., and Chandan Guha, M.B.B.S., Ph.D., at Albert Einstein College of Medicine have received a five-year, $2.6 million NIH grant to make immunotherapy agents that are more precise and effective at treating various types of cancers.

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A study published online today in Nature by Albert Einstein College of Medicine scientists suggests that it may not be possible to extend the human life span beyond the ages already attained by the oldest people on record.

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Researchers at Albert Einstein College of Medicine have received a five-year, $3.9 million National Institutes of Health grant to investigate the role of the gut microbiome in the development of type 2 diabetes among Hispanics/Latinos, the fastest-growing segment of the U.S. population. Hispanics in the U.S. have a 66 percent higher rate of diabetes than non-Hispanic whites (11.8 percent versus 7.1 percent). Since therapies can alter the microbiome in the gut, the research could lead to strategies for preventing and treating diabetes. Einstein co-principal investigators on the grant are Robert C. Kaplan, Ph.D., and Robert D. Burk, M.D., Rob Knight, Ph.D. at University of California San Diego is also a co-principal investigator.

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In research published in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles’ heel shared by all known types of Ebola virus. Two antibodies developed with this strategy blocked the invasion of human cells by all five ebolaviruses. The team included scientists from Albert Einstein College of Medicine, U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Integrated Biotherapeutics, Vanderbilt University Medical Center, and The Scripps Research Institute.

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Tuberculosis (TB) is the leading cause of death worldwide among people infected with HIV. But as yet, no test can reliably show when latent (inactive) TB infections in people with HIV starts progressing to active—and potentially fatal—TB disease. Now, a researcher at Albert Einstein College of Medicine has received a five-year, $3.7 million National Institutes of Health grant to identify biomarkers that signal an increase in activity by Mycobacterium tuberculosis (Mtb), the bacterium that causes TB, in people with HIV.

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Albert Einstein College of Medicine and Montefiore, in collaboration with the City University of New York (CUNY), have received a $9.4 million grant from the National Institutes of Health (NIH) to lead research in Central Africa to improve clinical care and health outcomes for patients with HIV. The ongoing, five-country observational study, called Central Africa International Epidemiologic Databases to Evaluate AIDS (CA-IeDEA), involves more than 50,000 HIV-positive children and adults taking anti-retroviral therapy (ART).

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More than one-third of Bronx residents are born outside of the United States. Often separated from family, challenged by language barriers, unfamiliar with health resources, and burdened by poverty, they are at high risk for health problems. And these risks extend to their young children.

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In a study of nearly 3,000 people, Einstein researchers have found that those who live 95 years or more are able to stave off age-related disease, with serious sickness compressed into only a few years late in life.

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Cristina Gonzalez, M.D., M.Ed., associate professor of clinical medicine at Albert Einstein College of Medicine and attending physician at Montefiore, has been selected as a 2016 Macy Faculty Scholar. One of only five chosen nationally, Dr. Gonzalez will receive a $100,000 grant from the Josiah Macy Jr. Foundation to allow her to pursue her medical education research and curriculum development.

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Researchers, led by Michael Lipton, M.D., Ph.D., at Albert Einstein College of Medicine and Montefiore Health System, using an advanced imaging technique, have been able to predict which patients who’d recently suffered concussions were likely to fully recover.

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Many young adults with abdominal obesity exhibit a readily detectable risk factor for chronic kidney disease (CKD), yet the vast majority don’t know they’re at risk, according to a study of nationwide health data led by Albert Einstein College of Medicine researchers that was published online today in the journal PLOS ONE.

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Albert Einstein College of Medicine has named Kamran Khodakhah, Ph.D. chair of the Dominick P. Purpura Department of Neuroscience . Dr. Khodakhah, who has been interim chair of the department since 2013, will assume his new role on [Month Day], 2016.

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For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to “see” single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

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Luciano D’Adamio, M.D., Ph.D., professor of microbiology & immunology at Albert Einstein College of Medicine, has received a five-year, $3.6-million grant from the National Institutes of Health to continue his research into how APP is processed in the brain.

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Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person’s own tissue. But no “autoantigens”—the proteins triggering an immune attack—have been linked to JIA.

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Headlines about America’s worsening drug epidemic have focused on deaths from opioids—heroin and prescription painkillers such as OxyContin. But overdose deaths have also soared among the millions of Americans using benzodiazepine drugs, a class of sedatives that includes Xanax, Valium, and Klonopin, according to a study led by researchers at Albert Einstein College of Medicine, Montefiore Health System and the Perelman School of Medicine at University of Pennsylvania. Their findings appear online today in the American Journal of Public Health.

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Researchers, led by Ilir Agalliu, M.D., and Robert Burk, M.D., at Albert Einstein College of Medicine have found that when human papillomavirus (HPV)-16 is detected in peoples’ mouths, they are 22 times more likely than those without HPV-16 to develop a common type of head and neck cancer.

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Researchers at Albert Einstein College of Medicine and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) have engineered the first antibodies that can potently neutralize the two deadliest strains of the virus that causes Ebola hemorrhagic fever. The findings, made in mice, are a significant step toward immunotherapies that are effective against all strains of Ebola virus that cause human disease. The study was published online today in Scientific Reports.

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Ebola virus and bats have been waging a molecular battle for survival that may have started at least 25 million years ago, according to a study led by researchers at Albert Einstein College of Medicine, the University of Colorado-Boulder (CU-Boulder) and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) that published online today in the journal eLife. The findings shed light on the biological factors that determine which bat species may harbor the virus between outbreaks in humans and how bats may transmit the virus to people.

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Feeling stressed out increases the likelihood that elderly people will develop mild cognitive impairment—often a prelude to full-blown Alzheimer’s disease. In a new study, scientists at Albert Einstein College of Medicine and Montefiore Health System found that highly stressed participants were more than twice as likely to become impaired than those who were not. Because stress is treatable, the results suggest that detecting and treating stress in older people might help delay or even prevent the onset of Alzheimer’s. The findings were published online today in Alzheimer Disease & Associated Disorders.

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Investigators at Montefiore Einstein Center for Cancer Care (MECCC), Albert Einstein College of Medicine’s NCI–designated Albert Einstein Cancer Center and The Children’s Hospital at Montefiore will present their research findings at the American Society of Hematology’s (ASH) 57th Annual Meeting and Exposition. Presentations include the first report on a genetic risk factor for avascular necrosis associated with treatment of acute lymphoblastic leukemia (ALL) in children along with new insights into the molecular basis for acute myeloid leukemia (AML) and a novel approach to the treatment of this disease. ASH 2015 will take place December 5-8, 2015 at the Orange County Convention Center in Orlando, Florida.

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Investigators at Albert Einstein College of Medicine received $148 million in research funding from the National Institutes of Health during the federal fiscal year of 2015. Below are some highlights of those received between July 1 and September 30.

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Now that researchers have successfully sequenced the human genome, understanding how those genes operate is one of the next great challenges. To that end, Albert Einstein College of Medicine is taking the lead role in a five-year, $4.25 million grant awarded by the National Institutes of Health (NIH) to develop tools that can image genes and the proteins for which they code.

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Anne R. Bresnick, Ph.D., an acclaimed cancer researcher, has been named director of the Belfer Institute for Advanced Biomedical Studies at Albert Einstein College of Medicine, effective October 1. Dr. Bresnick, professor of biochemistry, succeeds Jonathan M. Backer, M.D., who was recently named chair of the department of molecular pharmacology at the College of Medicine.

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An estimated 25 to 50 percent of preschoolers do not get enough healthy sleep. Now, researchers at Albert Einstein College of Medicine have been awarded a five-year, $2.9 million grant from the National Institutes of Health to promote healthy sleep among these children. The investigators will partner with Head Start, the early childhood program for disadvantaged preschool children and their families.

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Jonathan M. Backer, M.D., an internationally acclaimed molecular pharmacologist and sought-after mentor to promising young scientists, will chair the department of molecular pharmacology at Albert Einstein College of Medicine, effective September 17, 2015. Dr. Backer is professor of molecular pharmacology and biochemistry. The department’s prior co-chairs were Susan B. Horwitz, Ph.D., and Charles S. Rubin, Ph.D.

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Steven C. Almo, Ph.D., an internationally recognized leader in the field of proteomics, has been named chair of the department of biochemistry at Albert Einstein College of Medicine. Dr. Almo is professor of biochemistry and of physiology & biophysics and holds the Wollowick Family Foundation Chair. Dr. Almo will assume the chair left vacant by Vern Schramm, Ph.D., who has led the biochemistry department for the past 28 years.

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New research on sickle cell disease (SCD) has found that using antibiotics to deplete the body’s microbiome may prevent acute sickle cell crisis and could offer the first effective strategy for warding off the disease’s long-term complications, such as organ failure. The study, conducted by scientists at Albert Einstein College of Medicine and Montefiore Health System, could also lead to better treatment for other inflammatory blood-vessel disorders including septic shock. The findings were published online today in Nature.

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Researchers at Albert Einstein College of Medicine (http://www.einstein.yu.edu/) and Montefiore Health System (http://www.montefiore.org/) have received a $1.2 million grant from New York State to advance their promising technology for treating paralysis and other effects of spinal cord injuries (SCI). The grant is one of nine totaling $5.7 million announced by Governor Cuomo. The funding will be administered by New York State Spinal Cord Injury Research program and represents the first round of competitive awards since funding was re-instated for the program in 2013.

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Using real-time, high-resolution imaging, scientists have identified how a “doorway” in the blood vessel wall allows cancer cells to spread from breast tumors to other parts of the body. The findings support emerging tests that better predict if breast cancer will spread, which could spare women from unnecessary treatments and lead to new anti-cancer therapies. The research from Albert Einstein Cancer Center and Montefiore Einstein Center for Cancer Care published today in Cancer Discovery.

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An innovative three-month elective course has helped make some first-year medical students at Albert Einstein College of Medicine more confident about dealing with health disparities they’ll likely encounter as physicians, according to a follow-up study published online today in the journal Academic Medicine.