Scientists at St. Jude Children’s Research Hospital have identified how metabolic signaling pathways influence key immune cells with implications for treating autoimmune disorders and cancer.
The St. Jude Children's Research Hospital inpatient Nurse Residency Program has been accredited by the American Nurses Credentialing Center (ANCC) as a Practice Transition Program.
Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors.
For the second time, St. Jude Children's Research Hospital has received the prestigious Magnet®️ designation by the American Nurses Credentialing Center (ANCC). Magnet®️ is the gold standard for nursing and represents the highest international recognition awarded by the ANCC.
St. Jude Children’s Research Hospital has been designated as a von Hippel-Lindau Clinical Care Center by the VHL Alliance. St. Jude is the first and only VHL Alliance-recognized Clinical Care Center dedicated solely to children.
The National Cancer Institute award provides extended support for researchers to pursue projects with groundbreaking cancer research potential
St. Jude researchers capture the structure of PARP enzymes at work, leading to a new understanding of DNA repair that may aid cancer treatments targeting the process.
St. Jude Children’s Research Hospital will begin constructing The Domino’s Village, a new housing facility for patients and their families, this fall at 361 N. Third Street in Memphis, Tennessee.
St. Jude researchers showed that an inherited variant of the GATA3 gene is tied to minimal residual disease levels and response to therapy for acute lymphoblastic leukemia.
The COVID-19 pandemic turned our society on its head. One of the changes was a strange new reality where parents became school teachers overnight.
Reducing neuroinflammation by disrupting a protein involved in recycling cellular components may provide a potential therapeutic approach for treating neurodegeneration and memory loss.
St. Jude nurse leader Belinda N. Mandrell, PhD, RN, named a fellow of the American Academy of Nursing
Scientists at St. Jude Children’s Research Hospital are studying how hearing loss can affect the neurocognitive abilities of childhood cancer survivors. Findings show that survivors with severe hearing loss are at a significant increased risk for neurocognitive deficits, independent of what type of therapy they receive.
Behavioral scientist will lead St. Jude community outreach and research programs focused on the prevention of HPV-associated cancers through vaccination
St. Jude Children’s Research Hospital scientists have developed software to identify cancer-causing mutations lurking in vast regions of the human genome
St. Jude Children’s Research Hospital develops the Childhood Solid Tumor Network data portal to speed discoveries and novel therapies for treatment of childhood solid tumors
Genomic research helps explain why some people with a common TP53 mutation widespread in Brazil get cancer while others do not.
Researchers worldwide can access orthotopic patient-derived xenograft models to speed discovery and test novel therapies for childhood brain tumors.
The American Association for Cancer Research honored St. Jude President and CEO James R. Downing, M.D., with its inaugural AACR-St. Baldrick’s Foundation Award for Outstanding Achievement in Pediatric Cancer Research.
Dylan Graetz, M.D., M.P.H., a pediatric hematology-oncology fellow at St. Jude, has received a Young Investigator Award from the American Society of Clinical Oncology.
St. Jude Children’s Research Hospital software enables detection of previously unknown cancer-causing gene fusions, pointing the way to new treatments.
Scientists at St. Jude Children’s Research Hospital, UCSF Benioff Children’s Hospitals and Baylor College of Medicine are investigating how to best treat hemophagocytic lymphohistiocytosis (HLH), a rare immune disorder. Their work, appearing as an advance online publication today in Blood, details how combining two drugs may be a good treatment for HLH.
St. Jude researchers look at the combined effect of cancer treatments and inherited mutations in DNA-repair genes.
St. Jude Children’s Research Hospital has received a National Science Foundation grant to integrate biology and engineering at the molecular level to tackle childhood disease.
A leading expert in pediatric neurologic disorders, Richard Finkel, M.D., will lead the new Center for Experimental Neurotherapeutics at St. Jude Children’s Research Hospital
Douglas R. Green, Ph.D., of St. Jude elected to the National Academy of Sciences for his contribution to understanding the mechanism of cell death and survival.
St. Jude Children’s Research Hospital, in partnership with the International Society of Paediatric Oncology (SIOP), today launched the Global COVID-19 Observatory and Resource Center for Childhood Cancer.
Researchers identified the mechanisms underlying the innate immune function of the enzyme caspase-6, offering ways to combat viral infection, inflammatory diseases and cancer.
Malaria is a leading killer of children worldwide, and new drugs are needed. New research reports encouraging early clinical results with a new compound.
Spending $20 billion per year for 30 years would yield a 3-to-1 productivity gain of almost $2 trillion to the global economy according to St. Jude Global director and Lancet Oncology Commission co-chair.
Collaboration co-led by researchers at St. Jude Children’s Research Hospital discovers a novel predisposition gene in pediatric medulloblastoma.
Scientists at St. Jude Children’s Research Hospital have identified a novel target for a type of pediatric brain tumor.
Scientists at St. Jude Children’s Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy.
Drug resistance is a leading cause of cancer death in children and adults with leukemia. St. Jude Children’s Research Hospital scientists have developed a novel strategy to find the genes responsible.
St. Jude Children's Research Hospital pediatrician and researcher is honored for significant contributions to the advancement and impact of global collective efforts to save more lives from childhood cancer.
Researchers have found that genetically defined subpopulations of leukemia cells present at diagnosis have distinct characteristics that lead to relapse.
Scientists at St. Jude Children’s Research Hospital have implicated two microRNAs in the biological processes that underlie the ventricle enlargement observed in models of schizophrenia.
The Together website by St. Jude offers information about diseases, diagnosis and treatment options, as well as supportive care resources and shared stories of hope, healing and experience.
Ten years ago this week St. Jude Children’s Research Hospital and Washington University School of Medicine unveiled an ambitious collaboration to identify the genetic changes that lead to some of the world’s deadliest childhood cancers. The researchers proposed a three-year, $65 million project to sequence the complete normal and cancer genomes of more than 600 childhood cancer patients.
一项合作临床试验得出了如何使用靶向疗法治疗费城染色体导致的白血病的最新重要发现。
Researchers from St. Jude Children’s Research Hospital and the Chinese Children’s Cancer Group led the first randomized, Phase III clinical trial comparing targeted therapies for acute lymphoblastic leukemia (ALL) driven by the Philadelphia chromosome. Results showed that the drug dasatinib provides more benefit than the standard of care, which led to changes in the way this leukemia is treated. The findings were reported today in JAMA Oncology.
The Public Relations Society of America, the nation’s leading professional organization serving the communications community, recently announced the election of Echelle Jobe Rutschman to its College of Fellows.
Akshay Sharma, MBBS, of St. Jude Children's Research Hospital, is the recipient of a 2020 Scholar Award from the American Society of Hematology (ASH). One of ASH’s most prestigious research award programs, the ASH Scholar Award provides financial support to an early career hematology researcher.
Scientists at St. Jude Children’s Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process. The findings appeared online today in the Journal of Experimental Medicine.
St. Jude Children’s Research Hospital announced today that Elizabeth Fox, M.D., has been named senior vice president of clinical trials research.
A study from St. Jude Children’s Research Hospital sheds light on the mechanisms governing feeding behavior in fruit flies and how skeletal muscle communicates energy needs to the brain.
Results from a study conducted by St. Jude Children’s Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.
Researchers from St. Jude Children’s Research Hospital will present their work at the 61st annual meeting of the American Society of Hematology.
The Guardian of Excellence Award recognizes top-performing health care organizations that have achieved the 95th percentile or above of performance in Patient Experience in Pediatrics.
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