UC San Diego Health and the Altman Clinical and Translational Research Institute will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the coronavirus that causes COVID-19.
Recent animal experiments showed that LEAPS COVID 19 conjugates induced faster and much higher than expected antibody responses against a non-mutating region of the virus that causes COVID 19, after only one injection.
In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease. The research is the latest example of a decoy strategy researchers at Rensselear Polytechnic Institute are developing against viruses like the novel coronavirus that spawned the current global health crisis.
At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying to fight the disease can end up increasing inflammation and making atherosclerosis cases even worse.
Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research. Suggesting phage therapy could provide a potential treatment for managing such infections, including those involving antibiotic-resistant microbes.
CAR-T cell therapy, which attacks cancer cells using a person’s reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial.
• Studies conducted in mouse models, patients with cystic fibrosis, and different types of cells have helped to define how cystic fibrosis affects the kidneys.
• A urine test may help to assess aspects of cystic fibrosis in patients, which may be useful for testing the effectiveness of new medications.
As several Neandertal genomes of high quality are now available researchers can identify genetic changes that were present in many or all Neandertals, investigate their physiological effects and look into their consequences when they occur in people today.
Researchers from BIDMC report on the decline of emergent medical, surgical and obstetric hospitalizations at the medical center during the six-week period following the week of the declaration of the COVID-19 public health emergency in Boston in mid-March 2020.
Many Black men suffer symptoms of traumatic stress in the aftermath of traumatic injury, and they also often carry social concerns, including experiences of discrimination and stigma. Yet despite their significant needs, underserved populations often have limited access to behavioral health care as well as a lack of financial resources to pay for such care. Because of these barriers, many trauma survivors do not seek professional behavioral health care and instead rely on informal or alternative sources of care.
Advanced Urology proudly announces the opening of new satellite offices in Buckhead, Canton, Braselton, and Cumming to provide more patients with the opportunity to receive the best possible urological care from top-notch, board-certified physicians.
According to an open-access article published in ARRS' American Journal of Roentgenology (AJR), lung ultrasound (US) was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features.
NYU School of Global Public Health is embarking on a series of studies to evaluate the risks and impact of the COVID-19 pandemic on one of the city’s essential workforces: transit workers. This research will be conducted in coordination with the Transport Workers Union (TWU) Local 100, representing more than 40,000 New York City bus and subway workers.
The Rutgers Center for Advanced Biotechnology and Medicine and DuPont Nutrition & Biosciences have announced a new collaboration in the field of microbiome science they hope will improve cancer treatment.
DALLAS – July 23, 2020 – Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows. The findings, reported in a recent issue of PNAS, could shed light on Type 2 diabetes and other insulin resistance disorders, which remain poorly understood despite decades of study.
Researchers at Washington University School of Medicine in St. Louis have combined two immunotherapy strategies into a single therapy and found, in studies in human cells and in mice, that the two together are more effective than either alone in treating certain blood cancers, such as leukemia.
Researchers at UC San Diego Health have joined a national research study called Hyperbaric Oxygen Brain Injury Treatment (HOBIT) to assess whether therapy involving 100 percent oxygen under pressure might also benefit patients with severe brain injuries.
A new cell profiling technology combines high throughput imaging and machine learning to provide a rapid, cost-effective way to determine how specific compounds act to destroy the bacterium that causes tuberculosis. It could speed discovery of anti-TB drugs and be applied to other pathogens.
Texas Biomedical Research Institute (Texas Biomed) scientists have added another tool to the COVID-19 toolbelt, validating a new small animal model for studying SARS-CoV-2, the virus that causes COVID-19.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Copper, a metal commonly used throughout history for its antibacterial properties, is being utilized by researchers at IUPUI to solve a problem very relevant today: making reusable face masks safer and more comfortable for daily use.
People age 80 and older account for 19% of patients at Cedars-Sinai, a figure that is expected to increase in the coming years as the general U.S. population ages. The proportion of these patients who are low-income also is growing. Nurse scientists from the Nursing Research Department at Cedars-Sinai are now studying how best to address preventive health services among older patients like these while reducing the potential strain on long-term care, hospitals and the healthcare system.
Although rates of surgery for Crohn’s disease have decreased over the years, many patients still require surgical treatment – due to inadequate responses to medical therapy, severe attacks of acute colitis, and many other situations. Reflecting the latest research evidence and clinical practice, an updated set of recommendations for surgery in patients with Crohn’s disease have been published in Diseases of the Colon & Rectum (DC&R), the official journal of the American Society of Colon and Rectal Surgeons (ASCRS). The journal is published by Wolters Kluwer.
Friends’ drinking behaviors may be key to risky drinking among pregnant teens and young adults, according to a new study. Researchers used a previously untried approach to examine the ways that adolescents’ and young adults’ alcohol use and beliefs before they become pregnant related to their drinking as they entered into motherhood. Young mothers may be particularly vulnerable to moderate or heavy drinking during pregnancy, with adverse outcomes for their babies. Understanding the factors that influence risky alcohol use in pregnancy (3+ drinks per occasion) is important for identifying and supporting at-risk teens and young adults. The study in Alcoholism: Clinical & Experimental Research may be the first to use data collected before pregnancy, minimizing inaccurate recall.
Long-term heavy drinking and alcohol dependence are linked to multiple health problems, including premature death. The risk of serious harm is higher for women than men, and also depends on the person’s current level of drinking. However, it is not known if other factors, such as previous drinking history and co-existing psychiatric conditions, might also contribute to early death in people with alcohol dependence. One way to evaluate the impact of these factors is to group patients based on clusters of characteristics and assess outcomes in each group. Alcohol dependence ‘subtypes’ have previously been used to group patients for treatment planning purposes, but have not been assessed for their role in predicting long-term outcomes of alcohol dependence. A new study, reported in Alcoholism: Clinical and Experimental Research, has evaluated four alcohol dependence subtypes as predictors of relapse in the year after treatment, and as predictors of mortality over 36 years of follow-up.
Hackensack Meridian Jersey Shore University Medical Center was named to Newsweek’s 2020 list of Best Maternity Care Hospitals. The distinction recognizes facilities that have excelled in providing care to mothers, newborns, and their families, as verified by the 2019 Leapfrog Hospital Survey.
The NCCN Oncology Research Program (ORP) today announced four projects selected to receive funding for clinical and pre-clinical evaluation of futibatinib (TAS-120) in collaboration with Taiho Oncology.
The American Society for Radiation Oncology (ASTRO) has selected 19 distinguished members to receive the ASTRO Fellow (FASTRO) designation. The 2020 class of Fellows will be recognized at a virtual awards ceremony on October 27 during ASTRO’s 62nd Annual Meeting.
Feeling sleepy, bookworms? Chances are you’re not alone. A new survey from the American Academy of Sleep Medicine (AASM) reveals that a majority (66%) of U.S. adults report losing sleep due to reading “past their bedtime.”
A new study suggests that communication between skeletal muscle cells and muscle fibers promotes muscle growth. Adult muscle stem cells, called satellite cells, release extracellular vesicles that are delivered to muscle fibers responsible for contraction, to promote this muscle growth. The first-of-its-kind study is published ahead of print in the journal Function.