Filters close
Released: 4-Feb-2020 4:55 PM EST
Researchers successfully test coin-sized smart insulin patch, potential diabetes treatment
University of North Carolina School of Medicine

UCLA bioengineers and colleagues at UNC School of Medicine and MIT have further developed a smart insulin-delivery patch that could one day monitor and manage glucose levels in people with diabetes and deliver the necessary insulin dosage.

   
28-Jan-2020 9:05 AM EST
Discovery would allow researchers to fine-tune CAR-T activity
University of North Carolina Health Care System

In a study published in Cancer Cell, researchers reported new findings about the regulation of co-stimulatory molecules that could be used to activate cancer-killing immune cells – chimeric antigen receptor T-cells, or CAR-T – or decrease their activity.

21-Jan-2020 11:10 AM EST
Researchers Reverse HIV Latency, Important Scientific Step Toward Cure
University of North Carolina School of Medicine

Overcoming HIV latency – activating HIV in CD4+ T cells that lay dormant – is a needed step toward a cure. Scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare – showed it’s possible to drive HIV out of latency in two animal models.

Released: 21-Jan-2020 3:35 PM EST
Improving Cardiovascular Health of the Most Vulnerable
University of North Carolina School of Medicine

Starting in 2016, a two-year partnership between the North Carolina Chapter of the American College of Cardiology (NCACC) and the North Carolina Association of Free and Charitable Clinics (NCAFCC) provided free lipid lowering therapy and clopidogrel to patients at seven free clinics in North Carolina. The results of this pilot study were recently published in the Journal of the American College of Cardiology.

Released: 8-Jan-2020 5:05 PM EST
Researchers Detail Academic Scholarships Offered by E-Cigarette Entities
University of North Carolina School of Medicine

UNC School of Medicine researchers conducted a systematic online review and found 21 vaping-related companies, including, websites, that promoted 40 scholarships to high school and college students in 2018 across the United States.

Released: 2-Jan-2020 7:05 AM EST
The Ultimate Telemedicine: UNC Expert Helps Treat Astronaut’s Blood Clot During NASA Mission
University of North Carolina School of Medicine

Moll was the only non-NASA physician NASA consulted when it was discovered that an astronaut aboard the ISS had a deep vein thrombosis (DVT) – or blood clot – in the jugular vein of their neck.

Released: 19-Dec-2019 3:30 PM EST
Which Is More Effective for Treating PTSD: Medication, or Psychotherapy?
University of North Carolina School of Medicine

A new study that sought to find out whether serotonin reuptake inhibitors or trauma-focused psychotherapy is more effective in treating posttraumatic stress disorder (PTSD) concluded there is insufficient evidence at present to make that determination.

Released: 17-Dec-2019 12:20 PM EST
First U.S. Study Shows Strong Results for Minimally Invasive Procedure to Treat Knee Pain from Osteoarthritis
University of North Carolina School of Medicine

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis (OA). Principal investigator of the study, Ari Isaacson, MD, clinical associate professor of vascular and interventional radiology in the UNC School of Medicine, says the results are positive.

Released: 16-Dec-2019 1:10 PM EST
Scientists Show How Tiny, Mutated Neuron Antennae Impair Brain Connectivity
University of North Carolina School of Medicine

Even before we’re born, we need axons to grow in tracts throughout gray matter and connect properly as our brains develop. UNC School of Medicine researchers have now found a key reason why connectivity goes awry and leads to rare but debilitating neurodevelopmental conditions.

Released: 10-Dec-2019 3:35 PM EST
Lily and Yuh-Nung Jan Named 20th Perl-UNC Neuroscience Prize Recipients
University of North Carolina School of Medicine

The UNC School of Medicine has awarded the 20th Perl-UNC Neuroscience Prize to Lily Jan, PhD, and Yuh-Nung Jan, PhD, both at UC San Francisco, for the “discovery and functional characterization of potassium channels.”

Released: 25-Nov-2019 4:45 PM EST
Scientists Identify Underlying Molecular Mechanisms of Alexander Disease
University of North Carolina School of Medicine

This research marks the first time scientists have been able to model very specific chemical changes to the protein GFAP that occur inside the Alexander disease brain using an in vitro system derived from patient cells. This is allowing researchers to probe the details of how GFAP misfolding and accumulation alters cellular mechanics to lead to disease progression and death.

Released: 14-Nov-2019 11:05 AM EST
Findings could help identify aggressive breast cancers that will respond to immunotherapy
University of North Carolina Health Care System

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

11-Nov-2019 1:10 PM EST
Polygenic risk score improves psychosis risk prediction
University of North Carolina School of Medicine

A new study led by researchers at the University of North Carolina at Chapel Hill has found that that using a polygenic risk score (PRS) based on data from genome-wide association studies (GWAS) improves psychosis risk prediction in persons meeting clinical high-risk criteria.

4-Nov-2019 4:05 PM EST
CBD, THC Use During Early Pregnancy Can Disrupt Fetal Development
University of North Carolina School of Medicine

A new study published in Scientific Reports, a Nature Research journal, shows how a one-time exposure during early pregnancy to cannabinoids (CBs) – both synthetic and natural – can cause growth issues in a developing embryo. This is the first research to show such a connection in mammals.

Released: 24-Oct-2019 4:45 PM EDT
E-cigarette Flavors Decrease Perception of Harm Among Youth
University of North Carolina School of Medicine

University of North Carolina-Chapel Hill researchers found that non-menthol flavored e-cigarettes attract youth and adults to vape and that the use of flavored e-cigarettes contributes to multiple pathways linked to higher vaping rates among youth.

Released: 24-Oct-2019 12:40 PM EDT
Researchers Identify Possible Approach to Block Medulloblastoma Growth
University of North Carolina Health Care System

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.

Released: 14-Oct-2019 1:05 PM EDT
NCI grant to help patients navigate costs of cancer care
University of North Carolina Health Care System

The National Cancer Institute has awarded a four-year, more than $1.87 million grant to University of North Carolina Lineberger Comprehensive Cancer Center researchers to study the impact of implementing financial navigation services at five rural cancer centers in North Carolina to help patients cope with the financial burden, or financial toxicity, related to cancer care.

Released: 14-Oct-2019 10:05 AM EDT
New Heart Attack Registry to Provide Unprecedented Insight into STEMI Occurrence, Treatment in North India
University of North Carolina School of Medicine

A new study published in Clinical Cardiology introduces the North Indian (NORIN) ST‐Segment Elevation Myocardial Infarction (STEMI) Registry and provides preliminary data collected since its start in January of this year. The prospective cohort study’s first author, Sameer Arora, MD, UNC School of Medicine cardiology fellow and preventive medicine resident

9-Oct-2019 11:45 AM EDT
Scientists Make Surprising Discovery About Latent HIV Reservoir
University of North Carolina School of Medicine

HIV antiretroviral (ART) meds cannot completely eradicate the virus; it persists in immune cell “reservoirs.” Now scientists have discovered evidence that the initial use of ART alters the host environment to allow the formation or stabilization of most of the long-lived HIV reservoir.

Released: 9-Oct-2019 10:55 AM EDT
Goldstein to Use $2.7M NCI Grant to Develop, Test Warnings for Little Cigars, Cigarillos
University of North Carolina Health Care System

The National Cancer Institute has awarded a University of North Carolina Lineberger Comprehensive Cancer Center researcher a five-year, $2.7 million grant to develop more effective health warnings for little cigars and cigarillos.

3-Oct-2019 2:50 PM EDT
Restrictive Housing Is Associated with Increased Risk of Death After Release From Prison
University of North Carolina School of Medicine

A new study led by researchers at the University of North Carolina at Chapel Hill has found that being held in restrictive housing (i.e., solitary confinement) is associated with an increased risk of death after a person is released from prison.

Released: 30-Sep-2019 4:30 PM EDT
Researchers Publish Comprehensive Review on Respiratory Effects of Vaping
University of North Carolina School of Medicine

Studies show measurable adverse biologic effects on lung health and cells in humans, in animals, and in tissue samples studied in the lab. The effects of e-cigarettes have similarities to those seen in traditional cigarettes and important differences

Released: 20-Sep-2019 12:05 PM EDT
Long-Acting Injectable Multi-Drug Implant Shows Promise for HIV Prevention and Treatment
University of North Carolina School of Medicine

A new study published today in Nature Communications shows a promising alternative for those who have to take a daily pill regimen.

Released: 12-Sep-2019 11:05 AM EDT
Can scientists predict which cancer markers are likely to trigger an immune response?
University of North Carolina Health Care System

In a study published in the journal Cancer Immunology Research, University of North Carolina Lineberger Comprehensive Cancer Center researchers reported on the discovery of a method for predicting whether abnormal proteins produced by cancer cells could trigger an immune response.

Released: 11-Sep-2019 12:05 PM EDT
Exercising While Restricting Calories Could be Bad for Bone Health
University of North Carolina School of Medicine

A new study published today in the Journal of Bone and Mineral Research shows how bones in mammals are negatively impacted by calorie restriction, and particularly by the combination of exercise and calorie restriction.

30-Aug-2019 11:30 AM EDT
New Peanut Allergy Treatment Shows Effectiveness and Safety
University of North Carolina School of Medicine

Sublingual immunotherapy (SLIT) trial participants tolerated substantially more peanut protein than is common through accidental exposure. UNC School of Medicine researchers say SLIT (a tiny bit of liquid under the tongue) provides a good cushion of protection and a strong safety signal.

Released: 22-Aug-2019 11:05 AM EDT
Researchers Find Combined Therapy for Rheumatoid Arthritis May Help Speed Remission
University of North Carolina School of Medicine

Researchers found that patients with early rheumatoid arthritis (RA) may see less disease activity and higher remission rates after biologic therapy plus methotrexate (MTX) rather than either treatment alone.

Released: 22-Aug-2019 9:40 AM EDT
E-cigs Can Trigger Same Lung Changes Seen in Smokers, Emphysema
University of North Carolina School of Medicine

UNC scientists found that the lungs of vapers – like the lungs of smokers – have elevated levels of protease enzymes, a condition known to cause emphysema in smokers. The researchers also found that the nicotine in vaping liquids is responsible for the increase in protease enzymes.

Released: 14-Aug-2019 12:05 PM EDT
Scientists Find Powerful Potential Weapon to Overcome Antibiotic Resistance
University of North Carolina School of Medicine

Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more susceptible to some common antibiotics.

Released: 5-Aug-2019 3:55 PM EDT
UNC Center for Aging and Health Receives $3.75 Million Grant to Integrate Geriatrics throughout NC Primary Care Practices
University of North Carolina School of Medicine

The UNC School of Medicine’s Center for Aging and Health has received a five-year, $3.75 million grant from the Health Resources and Services Administration (HRSA) to provide geriatrics training throughout North Carolina.

Released: 1-Aug-2019 9:50 AM EDT
UNC collaborates with NC Department of Public Safety, Durham County Sheriff’s Office on opioid addiction treatment
University of North Carolina School of Medicine

Researchers from the University of North Carolina School of Medicine will collaborate with the North Carolina Department of Public Safety and the Durham County Sheriff’s Office to implement and evaluate two new opioid addiction treatment programs for people in the criminal justice system.

Released: 29-Jul-2019 10:05 AM EDT
First Patient Receives Surgery in UNC-Led International Pivotal Trial for Repair of Thoracoabdominal and Pararenal Aortic Aneurysms
University of North Carolina School of Medicine

The pivotal trial to determine the safety and effectiveness of a modular device designed to be the first completely off-the-shelf endovascular solution for aortic aneurysms involving the visceral branch vessels is successfully underway with its first surgery at UNC Hospitals in Chapel Hill, NC.

Released: 22-Jul-2019 1:05 PM EDT
New International Study Will Explore Accessibility of Talk Therapy Treatment for New Mothers
University of North Carolina School of Medicine

This study, co-led by Samantha Meltzer-Brody, MD, MPH, director of the UNC Perinatal Psychiatry Program, and Daisy Singla, PhD, assistant professor of psychiatry at University of Toronto and clinician scientist at Sinai Health System, will investigate how to make talk therapy treatment – specifically behavioral activation – more accessible to all women.

11-Jul-2019 12:05 PM EDT
Researchers identify anorexia nervosa genetic variants, redefine disorder as metabolic and psychiatric
University of North Carolina School of Medicine

A new large-scale genome-wide association study published in Nature Genetics, has identified eight genetic variants significantly associated with anorexia nervosa; and the research shows that the origins of this serious disorder appear to be both metabolic and psychiatric.

3-Jul-2019 4:05 PM EDT
Scientists Invent Fast Method for ‘Directed Evolution’ of Molecules
University of North Carolina School of Medicine

Nobel Prize-winning Directed evolution is an artificial, sped up process to make a protein perform a specified task. UNC School of Medicine scientists created a powerful new directed evolution technique for the rapid development of scientific tools and new treatments for many diseases.

   
27-Jun-2019 6:00 PM EDT
The Neuroscience of Autism: New Clues to the Condition's Beginnings
University of North Carolina School of Medicine

UNC School of Medicine scientists unveiled how a particular gene helps organize the scaffolding of brain cells called radial progenitors necessary for the orderly formation of the brain. Previous studies have shown that this gene is mutated in people with autism.

Released: 25-Jun-2019 9:00 AM EDT
UNC Health Care Launches Innovative Fully Integrated Epic Telehealth Solution
University of North Carolina Health Care System

UNC Health Care leads the innovation of telehealth by developing a fully integrated solution that enables patients to easily access providers through enhanced functionality of their My UNC Chart patient portal. Partnering with American Well, UNC Health Care launched the Telehealth (clinical) app into its Epic electronic health record (EHR) workflow that now offers patients video visits and video consultations with one click.

19-Jun-2019 10:05 AM EDT
Scientists discover new method for developing tracers used for medical imaging
University of North Carolina Health Care System

Scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers used in PET imaging.

18-Jun-2019 11:05 AM EDT
Scientists Make Single-cell Map to Reprogram Scar Tissue into Healthy Heart Cells
University of North Carolina School of Medicine

To heal hearts after heart attack, UNC School of Medicine researchers developed a stable, reproducible, minimalistic platform to reprogram human fibroblast cells in scar tissue into functional cardiomyocytes, the cells of healthy heart tissue.

   
Released: 14-Jun-2019 3:05 PM EDT
Researchers identify traits linked to better outcomes in HPV-linked head and neck cancer
University of North Carolina Health Care System

University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection.

Released: 11-Jun-2019 8:05 AM EDT
UNC receives $3.8 million grant to study “Med-South” weight loss program
University of North Carolina Health Care System

The Center for Health Promotion and Disease Prevention (HPDP) at the University of North Carolina at Chapel Hill has received a five-year, $3.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) to fund research that will address the challenge of achieving long-term weight loss among patients with obesity cared for at primary care practices.

Released: 31-May-2019 4:30 PM EDT
Study: Men with Early-Stage Prostate Cancer Who Choose Active Surveillance Often Don’t Follow Monitoring Guidelines
University of North Carolina Health Care System

Researchers found just 15 percent of a group of men with early-stage prostate cancer received biopsies and other tests according to active surveillance guidelines from the National Comprehensive Cancer Network.

Released: 24-May-2019 9:50 AM EDT
If You Could Learn Every Disease Your Child Could Possibly Develop in Life, Would You?
University of North Carolina School of Medicine

Newborn screening is required in the U.S. and differs slightly depending on which state you live in. For the most part, it’s done before a newborn baby leaves the hospital and includes a blood test that screens for 30-50 serious health problems that usually arise in infancy or childhood, and could hinder normal development.

Released: 10-May-2019 4:00 PM EDT
UNC-Led ACCURE Trial Remedies Racial Disparities in Treatment for Early-Stage Lung and Breast Cancer Patients
University of North Carolina School of Medicine

Results from a study published in The Journal of the National Medical Association show that a pragmatic system-based intervention within cancer treatment centers can nearly eliminate existing disparities in treatment and outcomes for black patients with early-stage lung and breast cancer.

Released: 9-May-2019 4:00 PM EDT
UNC and Partners Receive Up To $10.7 Million to Research Chlamydia Vaccine
University of North Carolina School of Medicine

Chlamydia is the most prevalent bacterial STI in the world. University of North Carolina at Chapel Hill researchers, in partnership with colleagues at sites in the US, Europe and Australia, will receive up to $10.7 million over five years from the NIH to move closer to identifying a vaccine.

Released: 1-May-2019 7:00 AM EDT
UNC School of Medicine Geriatrics Initiative Providing Special Care to Patients with Dementia
University of North Carolina School of Medicine

The Dementia Friendly Hospital Initiative will reach a total of 3,900 employees in four hospitals across North Carolina to raise awareness of how patients with dementia experience care, and to meet their unique needs with strategic and compassionate treatment.

18-Apr-2019 3:00 PM EDT
The Neurobiology of Noshing: Why is it so easy to overeat calorie-rich tasty foods?
University of North Carolina School of Medicine

Ever wonder why you really don’t want to stop eating delicious food even though you know you’ve eaten enough? UNC School of Medicine researchers may have found the reason – a specific cellular network motivated mice to keep eating tasty food even though their basic energy needs had been met.

   
Released: 17-Apr-2019 4:05 PM EDT
U.S. and Malawian Partners Implement Malaria Vaccine for Children in Africa
University of North Carolina School of Medicine

The first malaria vaccine will be tested in a pilot study beginning this April in three countries with a high burden of the disease among children, according to researchers leading the trial from UNC Project-Malawi. There, malaria is the main cause of illness and death among children under age 5.

Released: 15-Apr-2019 11:00 AM EDT
U.S. and Japanese Researchers Identify How Liver Cells Protect Against Viral Attacks
University of North Carolina School of Medicine

Researchers in Chapel Hill, N.C., and Tokyo have discovered a mechanism by which liver cells intrinsic resistance to diverse RNA viruses is regulated. These results have implications for for cellular responses to hepatitis, dengue and Zika.

1-Apr-2019 12:30 PM EDT
Discovery Shows How Mucus Build-up, Not Infections, Triggers Cystic Fibrosis Lung Damage
University of North Carolina School of Medicine

– The build-up of abnormally thick mucus and the associated inflammation appear to be the initiating cause of damage to the lungs of children with cystic fibrosis (CF), rather than bacterial infections, according to a UNC School of Medicine study published in Science Translational Medicine.



close
0.24022