A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson’s disease or dementia with Lewy bodies.
The first clinical trial to test a newly approved breast cancer drug specifically in African American patients is now enrolling at Georgetown Lombardi Comprehensive Cancer Center and will begin soon at five other institutions in Washington, DC, Maryland, Alabama and New Jersey.
You might not want to depend on your smartphone app alone to help you avoid or achieve pregnancy, say the authors of a new study. A review of nearly 100 fertility awareness apps finds that most don’t employ evidence-based methodology.
In what is believed to be the first study of its kind, researchers at Georgetown University Medical Center’s Institute for Reproductive Health (IRH) are recruiting as many as 1,200 women to study a smartphone app that calculates a woman’s chance for pregnancy on a daily basis.
What if private companies could obtain some coverage to protect their foreign investments in developing countries against crippling infectious disease outbreaks such as Ebola? The possible path to offering disease outbreak guarantees is an idea being posed by two global health researchers who suggest that a mechanism for establishing such an instrument could be tied to public health investments.
The manner in which pharmaceutical companies market their products to people who have hemophilia appears unprecedented and direct-to-consumer marketing should be examined by regulators, say researchers who reviewed documents, including consumer-oriented materials, produced by the makers of hemophilia treatment products.
Skilled readers can quickly recognize words when they read because the word has been placed in a visual dictionary of sorts which functions separately from an area that processes the sounds of written words, say Georgetown University Medical Center neuroscientists. The visual dictionary idea rebuts a common theory that our brain needs to “sound out” words each time we see them.
Georgetown University Medical Center and The Michael J. Fox Foundation for Parkinson’s Research announce a fellowship in regulatory science that will promote postgraduate training in the Parkinson’s research field to optimize clinical trial design and support approval of novel therapies.
A team of Georgetown University experts — a physician, a lawyer and an ethicist — are taking on an issue that occasionally confounds clinicians in the delivery room: should a physician, after helping deliver a child to a women whose genitals had been cut and vulva stitched together — an outlawed procedure generally called female genital mutilation or FGM — close her up again?
A growing body of research is revealing associations between birth defects and a father’s age, alcohol use and environmental factors, say researchers at Georgetown University Medical Center. They say these defects result from epigenetic alterations that can potentially affect multiple generations.
Georgetown University researchers are reporting the first case of Alzheimer’s disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer’s risk begins to escalate.
Safe levels of electrical stimulation can enhance your capacity to think more creatively, according to a new study by Georgetown researchers.
Rapid testing for the Zika virus is a critical need in the recent Ebola-affected countries of Liberia, Sierra Leone and Guinea, says a Georgetown University professor, because of the recent Zika outbreak on nearby Cape Verde and the similarity in symptoms between Zika and early Ebola.
Can we say goodbye to unreliable food diaries and diet recall in exchange for a urine test that will better aid researchers in figuring out what foods might help prevent cancer? Georgetown researchers have developed a method that can quickly evaluate specific food compounds in human urine.
The Huntington’s Disease Society of America has designated the Huntington Disease Care, Education and Research Center at Georgetown as an HDSA Center of Excellence for 2016. The designation comes with a grant to support services for Huntington disease patients and their families at the center, a collaboration between Georgetown University Medical Center (GUMC) and MedStar Georgetown University Hospital with generous support from the Griffin Foundation.
Two drugs that mimic a common plant hormone effectively cause DNA damage and turn off a major DNA repair mechanism, suggesting their potential use as an anti-cancer therapy.
Viewing graphic anti-smoking images on cigarette packs triggers activity in brain areas involved in emotion, decision-making and memory as observed via brain scans. Researchers from Georgetown University Medical Center and Truth Initiative reported their findings online this week in Addictive Behaviors Reports.
The Patient-Centered Outcomes Research Institute (PCORI), established under the Affordable Care Act, is charged with funding research that ultimately helps patients make better-informed health care decisions. But some at the forefront of such research — primary care physicians — say the grant money is not supporting the PCORI mission.
PINKconcussions and Georgetown University Medical Center are hosting the first summit to explore gender differences of female brain injuries including symptoms, treatment and recovery to develop a better model of care. The International Summit on Female Concussion and Traumatic Brain Injury will be held Saturday, Jan. 27 at Georgetown University.
When physicians, researchers and scientists gather at Georgetown University later this month, they will tackle what they say is an under-appreciated medical issue: brain concussions in girls and women. Former college athlete Melissa Coyne knows what a sports-related concussion can do.
Georgetown University Medical Center neuroscientists say rest — for more than a day — is critical for allowing the brain to reset neural networks and repair any short-term injury. The new study in mice also shows that repeated mild concussions with only a day to recover between injuries leads to mounting damage and brain inflammation that remains evident a year after injury.
The 10-question true or false digital quiz, produced by the Institute for Reproductive Health (IRH) at Georgetown University, probes the user’s understanding of fertility awareness. “If we could lift the taboos and improve fertility awareness, would people be informed and empowered to make better sexual and reproductive health decisions? At IRH, we believe the answer to this question is ‘yes.’”
Two Georgetown University professors say a section of the recently passed Congressional spending bill effectively undermines science and the health of women. Their JAMA Viewpoint, “A Public Health Framework for Screening Mammography: Evidence-Based Versus Politically Mandated Care,” will be published online Tuesday.
New and comprehensive analyses from six independent research teams examining breast cancer screening intervals have produced a unanimous finding — that mammography screening every two years for average risk women ages 50 to 74 offers a favorable balance of benefits to harm.
Even as the global malarial pandemic appears to be on a decline, drug resistant malarial parasites are on the rise, says an infectious disease researcher at Georgetown University Medical Center, who is taking the lead on a multi-institutional effort to investigate the causes of this growing concern.
An investigation into how often wheelchair users are killed in car-pedestrian crashes finds they are a third more likely to die than non-wheelchair users; more than half of those deaths occur at intersections.
WASHINGTON (Nov. 18, 2015) – The Ruesch Center for the Cure of Gastrointestinal Cancers at Georgetown Lombardi Comprehensive Cancer Center hosts “Fighting a Smarter War Against Cancer,” a symposium for medical professionals, patients and advocates, Dec. 3-5, 2015 at Georgetown University.
After a debate that has lasted more than 130 years, researchers at Georgetown University Medical Center have found that loss of speech from a stroke in the left hemisphere of the brain can be recovered on the back, right side of the brain. This contradicts recent notions that the right hemisphere interferes with recovery.
The results of common medical tests are sometimes delivered to patients by email, letters or voice mail, but are these the most preferred methods? According to one of the first studies to look at this question, the answer is no.
Little can be done to help the hundreds of thousands of people whose severe strokes have left them with one arm stuck close to the sides of their bodies like a broken wing. A 30-patient study by Washington researchers, however, has found that magnetically stimulating a specific part of their brains can affect arm movements — raising hope that, in the future, a short course of therapy targeting this area could help to free the arm and restore some use of the stroke-affected limb.
An FDA-approved drug for leukemia improved cognition, motor skills and non-motor function in patients with Parkinson’s disease and Lewy body dementia in a small phase I clinical trial, report researchers at Georgetown University Medical Center in Washington. In addition, the drug, nilotinib (Tasigna® by Novartis), led to statistically significant and encouraging changes in toxic proteins linked to disease progression (biomarkers).
A compound discovered and developed by a team of Georgetown Lombardi Comprehensive Cancer Center researchers that halts cancer in animals with Ewing sarcoma and prostate cancer appears to work against some forms of leukemia, too. That finding and the team’s latest work was published in Oncotarget.
One Team For The Cure shirts benefitting the Georgetown Lombardi Comprehensive Cancer Center in Washington, D.C. are now on sale online through One Team Shop (www.oneteamshop.com), the NFLPA’s e-commerce store featuring officially licensed player merchandise of more than 1,800 NFL players.
Neuroscientists have uncovered the brain malady responsible for tinnitus and for chronic pain — the uncomfortable, sometimes agonizing sensations that persist long after an initial injury.
A new animal study shows that traumatic brain injury (TBI) affects the body as well as the brain and that treatment with hypertension drugs blocks the production of proteins related to inflammation.
Identifying emerging infectious disease threats and incorporating biosecurity and bioethics in the development of medical technology are the foci of a new grant from the U.S. Department of State awarded to Georgetown’s Irene Jillson, PhD.
The largest nationwide clinical trial to study high-dose resveratrol long-term in people with mild to moderate Alzheimer’s disease found that a biomarker that declines when the disease progresses was stabilized in people who took the purified form of resveratrol.
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