An investigational drug that disrupts tumor blood vessels shows promise against a rare type of pancreatic cancer, scientists at Albert Einstein College of Medicine of Yeshiva University have found. Their results were presented October 20 during a poster session at an international cancer conference.
Gene mutations increase as people age, which helps explain why cancer usually strikes older people. But what other consequences of aging promote cancer development or protect against it? This is one of the 24 “Provocative Questions” that the National Cancer Institute (NCI) wants researchers to address. Now, a team of scientists at Albert Einstein College of Medicine of Yeshiva University has received a $2.8 million grant from NCI to investigate this question. The researchers will examine the role of epigenetics in causing lung cancer in people of different ages.
Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have received a $25 million grant from the National Institutes of Health (NIH) for the Harold and Muriel Block Institute for Clinical and Translational Research (ICTR) at Einstein and Montefiore. The two institutions received their initial Clinical and Translational Science Award (CTSA) from the NIH in 2008 to launch this joint collaboration.
Our ability to detect heat, touch, tickling and other sensations depends on our sensory nerves. Now, for the first time, researchers at Albert Einstein College of Medicine of Yeshiva University have identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell.
Findings from a study involving thousands of postmenopausal women suggest that women who develop invasive breast cancer may benefit from taking supplements containing both multivitamins and minerals. The new research, published today in Breast Cancer Research and Treatment, found that the risk of dying from invasive breast cancer was 30 percent lower among multivitamin/mineral users compared with nonusers.
The National Cancer Institute has awarded Albert Einstein Cancer Center at Albert Einstein College of Medicine a $16.7 million grant.
Behavioral abnormalities are traditionally thought to originate in the brain. But a new study by researchers at Albert Einstein College of Medicine of Yeshiva University has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity.
Scientists at Albert Einstein College of Medicine of Yeshiva University have shown that high-functioning autism spectrum disorder (ASD) children appear to outgrow a critical social communication disability. Younger children with ASD have trouble integrating the auditory and visual cues associated with speech, but the researchers found that the problem clears up in adolescence. The study was published today in the online edition of the journal Cerebral Cortex.
Researchers at Albert Einstein College of Medicine of Yeshiva University have found that community-based pharmacies can be effective locations for offering rapid HIV testing, diagnosing HIV, and connecting those who test positive with medical care quickly. The study publishes online today in the August issue of the journal AIDS Patient Care and STDs.
Researchers at Albert Einstein College of Medicine of Yeshiva University have found that nerves play a critical role in both the development and spread of prostate tumors. Their findings, using both a mouse model and human prostate tissue, may lead to new ways to predict the aggressiveness of prostate cancer and to novel therapies for preventing and treating the disease. The study published online today in the July 12 edition of Science.
Today, researchers at Albert Einstein College of Medicine of Yeshiva University convened a one-day conference on Jewish genetics designed to encourage collaboration and advance the field of research. Such research could help scientists identify causes and potential treatments for population-specific diseases as well as more common disorders afflicting the general population.
Researchers at Albert Einstein College of Medicine of Yeshiva University have shown that soccer players who frequently head the ball have brain abnormalities resembling those found in patients with concussion (mild traumatic brain injury). The study, which used advanced imaging techniques and cognitive tests that assessed memory, published online today in the journal Radiology.
Philip O. Ozuah, M.D., Ph.D., will deliver the keynote address at Albert Einstein College of Medicine’s 2013 commencement ceremony.
In a striking, unexpected discovery, researchers at Albert Einstein College of Medicine of Yeshiva University have determined that vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory culture. The finding suggests that vitamin C added to existing TB drugs could shorten TB therapy, and it highlights a new area for drug design. The study was published today in the online journal Nature Communications.
Albert Einstein College of Medicine researchers have discovered that chemo induces a type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation. The findings suggest that combining chemotherapy with nerve-protecting agents may prevent long-term bone marrow injury.
Two faculty members at Albert Einstein College of Medicine of Yeshiva University have been elected to the National Academy of Sciences. Robert Singer, Ph.D., and William Jacobs, Jr., Ph.D., were among the select scientists who will be inducted into the Washington-based organization at a ceremony in April 2014.
While the search continues for the Fountain of Youth, researchers may have found the body’s “fountain of aging”: the brain region known as the hypothalamus. For the first time, scientists at Albert Einstein College of Medicine of Yeshiva University report that the hypothalamus of mice controls aging throughout the body. Their discovery of a specific age-related signaling pathway opens up new strategies for combating diseases of old age and extending lifespan. The paper was published today in the online edition of Nature.
Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them. The experimental treatment dramatically decreased the number of metastases (cancers that have spread to other parts of the body) in a mouse model of highly aggressive pancreatic cancer without harming healthy tissue. The study was published today in the online edition of the Proceedings of the National Academy of Sciences.
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated. HIV-1 is the virus that causes AIDS, and the discovery could lead to novel approaches for addressing HIV-1 “in hiding” – namely eliminating reservoirs of HIV-1 that persist in patients undergoing antiretroviral therapy. The study was published today in the online edition of the journal Cell Host & Microbe.
Allen M. Spiegel, M.D., the Marilyn and Stanley M. Katz Dean of Albert Einstein College of Medicine of Yeshiva University, tonight publicly announced the College of Medicine’s largest fundraising effort—a capital campaign to raise at least $500 million, known as “The Campaign to Transform Einstein.”
Albert Einstein College of Medicine of Yeshiva University will join the New York Genome Center as its twelfth Institutional Founding Member. A collaboration among leading academic medical centers, research universities and commercial organizations, NYGC aims to transform medical research and clinical care by creating one of the largest genomics research facilities in North America.
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1). The finding, published online by The FASEB Journal, could lead to new drugs for treating or suppressing herpes virus infections.
Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages – white blood cells that play a key role in the immune response – also help to both produce and eliminate the body’s red blood cells (RBCs). The findings could lead to novel therapies for diseases or conditions in which the red blood cell production is thrown out of balance. The study, conducted in mice, is published today in the online edition of the journal Nature Medicine.
Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded a $12 million grant from the National Institutes of Health (NIH) to develop a drug-impregnated intravaginal ring to prevent HIV infection in women.
Researchers at Albert Einstein College of Medicine have discovered how the most common genetic mutations in familial Parkinson’s disease damage brain cells.
Sports-related concussion is an increasingly recognized public health problem. At least 1.6 million sports- and recreation-related traumatic brain injuries occur in the United States annually. While the primary focus has been on football, soccer has come under greater scrutiny. “Heading” in soccer may be largely safe, but in light of wide concern for repetitive mild brain injury, further investigation is required to determine if – and how much – “heading” can be done with little or no harm to the player.
John Condeelis, Ph.D., and Robert Singer, Ph.D., of Albert Einstein College of Medicine, will describe their imaging research at the AAAS Annual Meeting.
Male scientists are far more likely to commit fraud than females and the fraud occurs across the career spectrum, from trainees to senior faculty. The analysis of professional misconduct was co-led by a researcher at Albert Einstein College of Medicine of Yeshiva University and was published today in the online journal mBio.
U.S. News & World Report released today its Best Diets 2013 rankings, featuring a variety of weight loss programs. Among the experts tapped to evaluate the diets was Yasmin Mossavar-Rahmani, Ph.D., R.D., associate professor of clinical epidemiology & population health at Albert Einstein College of Medicine of Yeshiva University.
Children with sleep-related breathing problems (such as snoring or apnea) frequently have concurrent behavioral sleep problems (such as waking repeatedly).
Scientists at Albert Einstein College of Medicine of Yeshiva University have been awarded two Grand Challenges Explorations grants from the Bill & Melinda Gates Foundation for their innovative global health and development research projects.
Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that a special magnetic resonance imaging (MRI) technique may be able to predict which patients who have experienced concussions will improve. The results, which were presented today at the annual meeting of the Radiological Society of North America (RSNA), suggest that, in some patients, the brain may change to compensate for the damage caused by the injury.
During embryonic development, the all-important coronary arteries arise from cells previously considered incapable of producing them, according to scientists at Albert Einstein College of Medicine (http://einstein.yu.edu/) of Yeshiva University. The research, carried out in mice and published today in the online edition of the journal Cell, may speed development of regenerative therapies for heart disease.
Leading neurobiologist Michael Aschner, Ph.D., known for his research on the effect of heavy metals on the brain, will join the faculty of Albert Einstein College of Medicine of Yeshiva University. Dr. Aschner will be named professor of molecular pharmacology and of pediatrics.
Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University today named Judy Aschner, M.D., chair of the pediatrics department at The Children’s Hospital at Montefiore and professor and university chair of pediatrics at Einstein. Aschner joins from Monroe Carell Jr. Children’s Hospital at Vanderbilt University School of Medicine, where she has served as director of neonatology and the Julia Carell Stadler professor of pediatrics. She will assume her new position in April 2013.
A study by researchers at Albert Einstein College of Medicine of Yeshiva University suggests that body mass index (BMI)—the most commonly used weight-for-height formula for estimating fatness—may not be the best measure for estimating disease risk, and particularly the risk of certain types of cancer. The study was published today in the online edition of the American Journal of Epidemiology.
Albert Einstein College of Medicine of Yeshiva University has received a $3 million grant from the Glenn Foundation for Medical Research to establish the Paul F. Glenn Center for the Biology of Human Aging Research. The grant will fund research to translate recent laboratory and animal discoveries into therapies to slow human aging.
A team of researchers including Arturo Casadevall, M.D., Ph.D., of Albert Einstein College of Medicine, has found that misconduct is responsible for two-thirds of all scientific paper retractions.
The promise of stem cells seems limitless. If they can be coaxed into rebuilding organs, repairing damaged spinal cords and restoring ravaged immune systems, these malleable cells would revolutionize medical treatment. But stem cell research is still in its infancy, as scientists seek to better understand the role of these cells in normal human development and disease.
A team of researchers, led by Martha Grayson, M.D., at Albert Einstein College of Medicine, have found that debt and income expectations deter med school students from entering into primary care.
Why does cancer arise in certain parts of the body and not others? How exactly does it spread? These are critical questions that cannot be answered clearly despite decades of cancer research. Answers to complex but central questions about cancer have long stymied efforts to “win the war” on the disease.
The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, has awarded nearly $11 million to Albert Einstein College of Medicine of Yeshiva University to carry out a five-year multi-institutional study of hemoglobin toxicity that may complicate blood transfusions and reduce the effectiveness of blood substitutes. The long-term goals include making blood transfusions safer and more effective and better matching patients with the transfusion strategy best suited to them
Social media is increasingly popular but engaging in its proper use can prove confusing and challenging – especially in the medical and healthcare arenas. Albert Einstein College of Medicine (http://www.einstein.yu.edu/) of Yeshiva University has been awarded a two-year grant to educate faculty members and medical students on using social media appropriately and effectively. Einstein is one of four medical schools in the United States to be selected for the 2012 Education and Training to Professionalism Initiative by the Institute on Medicine as a Profession (IMAP) and the Josiah Macy Jr. Foundation.
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a new “first response” mechanism that the immune system uses to respond to infection. The findings challenge the current understanding of immunity and could lead to new strategies for boosting effectiveness of all vaccines. The study, conducted in mice, published online today in the journal Immunity.
Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a usually fatal cancer, are a step closer to new treatment options. Their study results were published online today in Cancer Cell.
A new genetic analysis focusing on Jews from North Africa has provided an overall genetic map of the Jewish Diasporas. The findings support the historical record of Middle Eastern Jews settling in North Africa during Classical Antiquity, proselytizing and marrying local populations, and, in the process, forming distinct populations that stayed largely intact for more than 2,000 years. The study, led by researchers at Albert Einstein College of Medicine of Yeshiva University, was published online today in the Proceedings of the National Academy of Sciences.
In a study published online in Science, researchers at Albert Einstein College of Medicine of Yeshiva University have determined the complete wiring diagram for the part of the nervous system controlling mating in the male roundworm Caenorhabditis elegans, an animal model intensively studied by scientists worldwide.
Compared to the general population, HIV-positive women have a high risk of cervical cancer and thus are advised to undergo more frequent screening tests. This creates a burden for HIV-positive patients and the health care system, leading to frequent biopsies, which often do not reveal clinically relevant disease.
Researchers at Albert Einstein College of Medicine (http://www.einstein.yu.edu/) of Yeshiva University have uncovered one of the mechanisms by which aging may compromise the ability of the immune system to fight infections and respond to vaccines. The study, conducted in aging mice, shows that administering antioxidants may help reverse this loss of immune function. The findings were published online this month in the journal Cell Reports.
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