A federally-funded study led by Johns Hopkins Medicine researchers discovered that communication among cells is altered in pregnant women who go on to develop postpartum depression (PPD) after giving birth.
In a study of more than 80 men and women from Baltimore, Maryland, Johns Hopkins researchers have added to evidence that COVID-19 booster shots are essential for maintaining long-term immunity against infection, particularly among older adults.
A new study focused on the immune system’s Th17 cells suggests that the shape and function of their mitochondria (the powerhouse of cells) is important in autoimmune and inflammatory disorders, such as multiple sclerosis.
It may soon be possible to identify Group 4 medulloblastomas—the most common malignant brain tumor in children--from more aggressive Group 3 tumors. Research based on a little-explored part of RNA, which creates proteins, could lead to the development of better-targeted cancer treating drugs, according to investigators at the Johns Hopkins Kimmel Cancer Center.
In a study using lab-grown cells, Johns Hopkins Medicine researchers specializing in aging report they have successfully delivered a common blood pressure drug directly to the inner membrane of mitochondria, the “power plants” in the cells of humans, animals, plants and most other organisms.
Johns Hopkins Medicine physicians and clinicians have conducted more than 1.5 million telemedicine visits with over 420,000 patients in Maryland, Washington, D.C., Florida and across the country since the start of the COVID-19 pandemic, according to the Johns Hopkins Office of Telemedicine.
Drew Pardoll, M.D., Ph.D., and Suzanne Topalian, M.D., leading cancer immunotherapy investigators in the Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy and Kimmel Cancer Center, have been named by the Society for Immunotherapy of Cancer (SITC) as Fellows of the Academy of Immuno-Oncology.
Thanks to two novel tools developed by a Johns Hopkins Medicine resident and a former resident, the traditionally difficult surgery to create a replacement ear from a patient’s rib cartilage may soon be done faster, more simply and accurately.
Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD).
Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson’s disease and halts movement problems in mice.
Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.
Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.
Johns Hopkins Medicine study suggests strategies may prevent dangerous post-surgery condition
In a survey study of more than 3,000 adults, Johns Hopkins Medicine researchers compared psychedelic experiences with near-death experiences that were not drug related and found notable similarities in people’s attitudes toward death.
As we approach the time of year when students switch from vacation mode to school mode, Johns Hopkins Children’s Center experts are available for interviews on a variety of back-to-school-related topics to share advice for a smooth start to the new school year.
In a multi-site study of medical records, researchers at Johns Hopkins Children’s Center and across the United States say they have documented a steep rise in type 2 diabetes among children during the COVID-19 pandemic.
Johns Hopkins Medicine researchers say they have evidence to potentially overturn a prevailing belief in a type of important signaling within cells. The mainstream idea is that a single protein receptor molecule — a kind of flag on the cell surface — spurs the activity of up to hundreds of downstream protein molecules to produce a signal.
In a lookback study of prescribing patterns among thousands of American ophthalmologists and optometrists, Johns Hopkins Medicine researchers concluded that eye doctors who receive even small financial incentives from pharmaceutical companies, such as free food, sponsored travel to attend meetings or consulting fees, are up to twice as likely to prescribe the companies’ brand name eyedrops for glaucoma instead of cheaper generic versions.
Johns Hopkins Medicine researchers say that an experimental dendrimer nanoparticle treatment called OP-101 substantially reduced the risk of death and need for a ventilator in a study of 24 severely ill adults hospitalized with COVID-19.
Older adults with atrial cardiopathy (a major, often undetected cardiac cause of stroke) may be at increased risk of developing dementia, according to new research led by Johns Hopkins Medicine.
In the pursuit of accurate diagnoses for illnesses, doctors have traditionally used multiple methods to try to identify the bacterium, virus, fungus or other pathogen responsible for an infection.
Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.
To address the global burden of tuberculosis (TB), one of humankind’s oldest scourges, an international collaboration led by Johns Hopkins Medicine has today been awarded up to $200 million in research funding over five years by the U.S. Agency for International Development (USAID) Supporting, Mobilizing and Accelerating Research for Tuberculosis Elimination (SMART4TB) project.
Early initiation of physical therapy (PT) for U.S. patients with acute lower back pain (LBP) was associated with less health care resource use in the first month and the first year after the initial onset of symptoms, according to a new study by Johns Hopkins Medicine.
Johns Hopkins Medicine researchers have helped develop a nanobody capable of getting through the tough exterior of brain cells and untangling misshapen proteins that lead to Parkinson’s disease, Lewy body dementia, and other neurocognitive disorders caused by the damaging protein.
In a new study, Johns Hopkins Medicine researchers tested more than 100 topical cannabidiol (CBD) products available online and at retail stores, and found significant evidence of inaccurate and misleading labeling of CBD content.
Johns Hopkins Medicine scientists report they have probed the atomic structure of proteins to add to evidence that the wobbles, shakes and quivers of proteins play a critical role in their ability to function. The findings of the research may help scientists design new drugs that can modify or disrupt the intricate “dances” of proteins to alter their functions.
In an analysis of medical information of more than 6,000 American adults with a history of cardiovascular disease (CVD), researchers at Johns Hopkins Medicine conclude that CVD risk “profiles” in secondary prevention have failed to improve over the last two decades.
Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing serious diarrheal infections, may also drive colorectal cancer.
In a Johns Hopkins Medicine study of patients who underwent adult spinal deformity (ASD) surgery, preoperative opioid use and pain duration of four or more years were independently associated with higher odds of chronic post-surgery opioid use.
Surveillance programs for people at high risk of developing pancreatic cancers can help detect precancerous conditions and cancers early, when they are most treatable, according to a new multicenter study directed by experts at the Johns Hopkins Kimmel Cancer Center.
Adults with abnormal heart metabolism are up to three times more likely to experience life-threatening arrhythmias (an irregular heart rhythm), and MRI techniques could be used to detect the condition and predict future sudden cardiac death (SCD), according to a small, but rigorous study led by Johns Hopkins Medicine researchers.
In a review of published research papers, investigators from the Johns Hopkins Medicine Hereditary Hemorrhagic Telangiectasia (HHT) Center have identified a substantial lack of racial and ethnic data that may be negatively impacting the treatment and diagnosis of this rare disorder in diverse patients.
As school ends, summer fun begins. Johns Hopkins Children’s Center experts say safety is the key to an enjoyable season for the whole family. Children’s Center experts are available to provide some top tips for the months ahead.
In a study of eye fluid from 38 patients, Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off the treatments.
The Mark Foundation for Cancer Research and the Bloomberg~Kimmel Institute for Cancer Immunotherapy (BKI) announced today a new $10 million commitment at The Johns Hopkins University to fund novel work and advance immunotherapy research to provide lifesaving breakthroughs to people with cancer.
Adult survivors of cancer have a higher risk of heart failure and other cardiovascular diseases (CVD) later in life than adults without cancer, according to results of a large study led by Johns Hopkins Medicine researchers.
A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.
Delivering a targeted immunotoxin into breast ducts via openings in the nipple wiped out all visible and invisible precancerous lesions in laboratory studies, led by researchers at the Johns Hopkins Kimmel Cancer Center, of very early stage breast cancers
A study analyzing prescription claims for a drug used to treat opioid addictions found that adolescents and young adults were less likely than usual to get treatment during the COVID-19 pandemic, especially if they were covered by private, commercial health insurance.
Researchers at Johns Hopkins Medicine have found that infertility is more common among women who are older, who are non-Hispanic Black and who have less income or education, and women without access to sexual and reproductive health services.
A common hormone disorder among women of reproductive age has been linked to an increased risk of adverse cardiovascular events and pregnancy outcomes at the time of birth, according to a new study led by Johns Hopkins Medicine researchers.
Among older adults with early stage — also known as preclinical — heart failure, uncontrolled diabetes can substantially increase the risk of heart failure progression, according to a new Johns Hopkins-led study.
A multi-institutional, international study, led by researchers at the Johns Hopkins Kimmel Cancer Center and WEHI in Melbourne, Australia, found that testing for ctDNA after surgery and directing chemotherapy to ctDNA-positive patients reduced the use of chemotherapy overall without compromising recurrence-free survival.
A recent study by Johns Hopkins Medicine researchers has revealed that consuming at least one cup of coffee a day may reduce the risk of acute kidney injury (AKI) when compared to those who do not drink coffee.
Scientists have long known that cocaine works by latching on to molecular connectors on the surface of brain cells, allowing dopamine, a chemical that promotes feelings of pleasure and reward, to accumulate in the space between brain cells. Now, Johns Hopkins Medicine scientists say they have found a molecular connector, known as the BASP1 receptor, that binds cocaine, even when the drug is present in very low doses.
New laboratory research directed by investigators at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins Bloomberg School of Public Health finds that secreted age-induced changes in distant sites such as the lung can effectively reactivate dormant cells and cause them to grow.
A retrospective analysis of over 7,000 patients with COVID-19 found that pulse oximeter devices — tools that measure oxygen levels in the blood and that are used in virtually every U.S. hospital — overestimated blood oxygen levels in non-White patients.
Johns Hopkins Medicine researchers say they discovered that a special sugar molecule could play a key role in the development of Alzheimer’s disease. If further research confirms the finding, the molecule, known as a glycan, could serve as a new target for early diagnostic tests, treatments and perhaps prevention of Alzheimer’s disease, say the researchers.
For a 14th year, the Johns Hopkins Institute for Basic Biomedical Sciences will gather journalists and science writers for the Science Writers’ Boot Camp — a free, daylong immersion in science and medicine that is focused on a particular area of interest.
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