A new study led by University of North Carolina School of Medicine researchers concluded that patterns of white matter microstructure present at birth and that develop after birth predict the cognitive function of children at ages 1 and 2.
Significant differences exist in the believability of specific cigar warnings, suggesting that more work is needed to establish the best warnings to dissuade youth from smoking cigars.
UNC Lineberger Comprehensive Cancer Center researchers and collaborators report Wednesday at the San Antonio Breast Cancer Symposium that they have identified biomarkers they believe can be used as part of a larger model to predict how patients with HER2-positive operative breast cancer will respond to the targeted treatment trastuzumab, commercially known as Herceptin, and chemotherapy.
A study presented Wednesday at the 2016 San Antonio Breast Cancer Symposium examined the incidence of brain metastasis after diagnosis for three groups of patients with HER2-positive breast cancer.
In a preliminary findings presented at the 2016 San Antonio Breast Cancer Symposium, researchers reported that older patients were as likely as younger patients to receive targeted therapy and enroll in therapeutic trials based on their sequencing results.
In a study presented at the 2016 San Antonio Breast Cancer Symposium, researchers report they developed a model that can predict which triple negative breast cancer patients will respond to chemotherapy.
Results from a new study show that online group therapy can be just as effective as face-to-face treatment, although the pace of recovery may be slower.
Lack of paid leave and outdated maternity care are barriers to breastfeeding that disproportionately impact families of color. This is the first study to show how these disparities translate into differences in health outcomes.
When Manda Miller called her parents to tell them she was pregnant, she knew it would be unexpected. But, starting a family was more than just a life detail on which Manda and Douglas Miller had been mum – Manda was a two-time survivor of Hodgkin’s Lymphoma. The aggressive treatment saved her life, but had taken her chance for children.
In the journal Tobacco Control, researchers report the results of a systematic review of 40 studies completed in the United States and internationally that looked at the impact of non-menthol tobacco flavors on consumers’ perceptions and tobacco use behaviors.
A malaria parasite in the Democratic Republic of the Congo is able to avoid rapid test detection through a gene deletion. In the first nationwide study, researchers at the University of North Carolina at Chapel Hill showed how the deletion prevents a positive test result in asymptomatic children.
We caught up with Qian, assistant professor of pathology and laboratory medicine at the UNC School of Medicine and member of the McAllister Heart Institute, to discuss her research in cardiac reprogramming, her goal to inspire young women to pursue careers in science, and how and why she chose the UNC School of Medicine. By Caroline Curran, caroline.
CHAPEL HILL, NC – Do you have questions about the Zika virus and how it spreads? If you’re traveling this holiday season, do you know how to protect yourself from Zika? Do you have questions about Zika and pregnancy? Do you know all the ways the virus can be transmitted? What about the likelihood of a Zika epidemic here in North Carolina?
Muscular dystrophies, congenital heart muscle defects, and other muscle disorders often arise for reasons that scientists don’t fully understand. Now researchers from the UNC School of Medicine and Baylor College of Medicine have discovered that alternative splicing could play an important role in these disorders.
Two researchers at the UNC School of Medicine have been named to a global consortium for Zika research and vaccine development.
During stroke or heart attack, tissue damage can be limited because “collateral” vessels connect the tissue to other arteries. Collateral vessels can vary greatly in size and number from one person to the next. Scientists have now implicated the Rabep2 gene as a major contributor to variation.
Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center report in the journal Cell Reports that certain short, repetitive sequences of DNA, or “junk,” play an important role in the development of Ewing sarcoma.
In the journal Cancer Epidemiology, Biomarkers & Prevention, researchers report that uninsured women under age 65 who received their mammogram at community screening clinics in North Carolina also were less likely to get follow-up within a year of a positive mammogram.
In a study in the journal Development, UNC Lineberger Comprehensive Cancer Center researchers report preclinical findings showing promise for targeting a gene linked to microcephaly in infants as a treatment for medulloblastoma.
A UNC School of Medicine dermatologist recently conducted a study to determine if the way a prescription was written – either traditionally or electronically – played a role in whether a patient filled and picked up the medication.
In a new study, researchers used a nationally-representative dataset to estimate the frequency with which emergency providers make a formal diagnosis of elder abuse. The answer: 1 in 7,700 visits.
Crohn’s disease can have devastating consequences and is notoriously hard to treat. Now, scientists have made a discovery that could explain why Crohn’s is so variable: the disease has at least two distinct subtypes, each with its own pattern of gene expression and mix of clinical features.
Doctors and public health officials differ on the potential long-term effects of vaping and the use of e-cigarettes as smoking cessation tools. But they agree the devices shouldn't explode in your face.
In the study published in the Journal of Clinical Oncology, UNC Lineberger researchers report that nearly a third of a group of patients with chronic myeloid leukemia, and who have federally-funded Medicare health insurance, did not start treatment within six months of diagnosis with any of three targeted drugs that have led to dramatic improvements in survival for the disease.
New research shows that breastfeeding is not only good for children, but also for their mothers, providing more health benefits and preventing more maternal diseases than previously known.
Findings of improved survival for patients with a type of head and neck cancer linked to HPV-16, and comparatively worse outcomes for other HPV strains, have treatment implications.
People under the age of 30 account for the majority of new HIV infections in the United States. This age group is also more likely than adults to own a smartphone. Recognizing adolescents’ connection with mobile technology, a research team at the University of North Carolina at Chapel Hill, along with colleagues at Emory University, has secured $18 million in funding over the next five years from the National Institutes of Health to form the UNC/Emory Center for Innovative Technology or iTech.
Researchers at the UNC School of Medicine announced the first evidence that stabilizing a protein called SOD1 can help reverse protein clumping in the types of neurons affected by the fatal neurodegenerative condition Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease.
In 2012, UNC Hospitals launched an initiative aimed at reducing the time it takes hospital staff to recognize when a patient is having a STEMI (ST elevation myocardial infarction) heart attack – the sudden and complete blockage of a heart artery – and to begin appropriate treatment. Now, encouraging results from that effort have been published as a research letter in JAMA Cardiology.
An analysis of the quality of life of several thousand breast cancer survivors in North Carolina found differences in how black and white women functioned and felt physically and spiritually during treatment and two years after diagnosis.
UNC School of Medicine scientists discover that a pair of large enzyme complexes attack each other in turn to form a molecular switch, which is essential for cell division.
For patients whose hearing is considered “too good” for traditional cochlear implants, but whose hearing loss is too advanced to benefit from hearing aids, there hasn’t been a device to meet their needs.
UNC investigators led by Stanley Lemon, MD, Professor of Medicine, discover how hepatitis A virus causes liver injury as well as how the virus could jump from primates to mice.
Researchers at the University of North Carolina (UNC) and the University of Minnesota (UMN) have been awarded a $4 million grant from the National Institutes of Health (NIH) to launch the Baby Connectome Project (BCP). The BCP aims to provide scientists with unprecedented information about how the human brain develops from birth through early childhood and will uncover factors contributing to healthy brain development.
University of North Carolina Lineberger Comprehensive Cancer Center researchers, by tracking a molecular marker that has been shown to increase in white blood cells as people age, have uncovered clues that suggest that stem cell transplant is linked to a marked increase in the “molecular age” of these immune cells in a group of patients with blood cancer.
Scientists discovered that the major developmental function of heterochromatin – a form of tight DNA packaging found in chromosomes – is likely the suppression of virus-like DNA elements known as transposons, which can copy and paste themselves throughout the genome, potentially causing diseases.
The U.S. Food and Drug Administration (FDA) on Friday issued an advisory that all U.S. blood banks screen donated blood for Zika virus.
In a paper published online by the Journal of the American Medical Association, UNC Lineberger Comprehensive Cancer Center physician-researchers raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.
University of North Carolina LIneberger Comprehensive Cancer Center researchers say the finding of a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States lays the foundation for future studies looking at whether payments influenced clinical practice or guideline recommendations.
Jason Katz, MD, MHS, associate professor of medicine at UNC School of Medicine and medical director of the cardiac intensive care unit, was the lead author of a recently published manuscript that examined the early growth and maturation of critical care cardiology, and the challenges and uncertainties that threaten to stymie the growth of this fledgling discipline.
UNC School of Medicine scientists mapped out a serotonin-driven anxiety brain circuit that may explain the acute anxiety side effect of antidepressant use.
With publications in prestigious medical journals and multimillion dollar federal grants, UNC faculty have shown they are committed to moving the fields of HIV prevention, treatment and cure research forward.
CHAPEL HILL, NC –UNC School of Medicine’s Anne Lyerly is addressing the urgent need for effective HIV prevention and treatment for the estimated 1.5 million women worldwide with HIV who give birth each year. Lyerly, associate director of the UNC Center for Bioethics and associate professor of social medicine at the UNC School of Medicine, is also an obstetrician/gynecologist who studies ethically complex clinical and policy issues related to women’s reproductive health.
UNC Lineberger researcher Carey Anders, MD, wants to understand why some breast cancer metastasize to the brain, and what drives them. She recently was awarded a three-year, $450,000 grant to study genetic features of breast cancer brain metastases to try to answer those questions.
Each year, 1.5 million women living with HIV become pregnant. Without effective treatment, up to 45 percent of HIV-infected mothers will transmit the virus to their child. In an effort to prevent HIV transmission to women and their children, researchers from the University of North Carolina at Chapel Hill demonstrated the effectiveness of a new anti-HIV medication, EFdA, in pre-clinical animal models.
Researchers at the University of North Carolina School of Medicine are conducting studies that utilize blood donations from individuals who have been diagnosed with or potentially exposed to mosquito-borne viruses as part of ongoing dengue and Zika research and vaccine development.
Researchers say breast reconstruction can help with self-esteem, sexuality and body image after mastectomy. But a University of North Carolina Lineberger Comprehensive Cancer Center study has found that the type of insurance a woman has as well as distance to a plastic surgeon's office can be barriers to the procedure.
For the first time, UNC School of Medicine scientists report using transcranial alternating current stimulation, or tACS, to target a specific kind of brain activity during sleep and strengthen memory in healthy people.
The study’s results will help improve health outcomes for mothers, their babies and future pregnancies.
A better understanding of HIV latency is the key to eradicating the virus researchers at the University of North Carolina and partner institutions write in a perspective in the journal Science.
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