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Released: 21-Oct-2014 5:00 PM EDT
Early Palliative Care Can Cut Hospital Readmissions for Cancer Patients
Duke Health

Doctors at Duke University Hospital have developed a new collaborative model in cancer care that reduced the rates at which patients were sent to intensive care or readmitted to the hospital after discharge. The Duke researchers shared their findings today at the Palliative Care in Oncology Symposium sponsored by the American Society of Clinical Oncology.

10-Oct-2014 10:00 AM EDT
Prostate Cancer’s Penchant for Copper May Be a Fatal Flaw
Duke Health

Like discriminating thieves, prostate cancer tumors scavenge and hoard copper that is an essential element in the body. But such avarice may be a fatal weakness.

Released: 13-Oct-2014 3:50 PM EDT
Stress May Be Harder on Women’s Hearts Than Men’s
Duke Health

Researchers have known for decades that stress contributes to heart disease. But a new analysis by researchers at Duke Medicine shows mental stress may tax women’s hearts more than men’s. The research appears online Oct. 13, 2014, in the Journal of the American College of Cardiology.

30-Sep-2014 9:00 AM EDT
Gene Interacts with Stress and Leads to Heart Disease in Some People
Duke Health

– A new genetic finding from Duke Medicine suggests that some people who are prone to hostility, anxiety and depression might also be hard-wired to gain weight when exposed to chronic stress, leading to diabetes and heart disease.

Released: 25-Sep-2014 10:00 AM EDT
Coping Techniques Help Patients With COPD Improve Mentally, Physically
Duke Health

Coaching patients with chronic obstructive pulmonary disease to manage stress, practice relaxation and participate in light exercise can boost a patient’s quality of life and can even improve physical symptoms, researchers at Duke Medicine report.

Released: 18-Sep-2014 2:00 PM EDT
New Insights on an Ancient Plague Could Improve Treatments for Infections
Duke Health

Dangerous new pathogens such as the Ebola virus invoke scary scenarios of deadly epidemics, but even ancient scourges such as the bubonic plague are still providing researchers with new insights on how the body responds to infections.

Released: 28-Aug-2014 12:00 PM EDT
New Analysis of Old HIV Vaccines Finds Potentially Protective Immune Response
Duke Health

Applying the benefit of hindsight, researchers at Duke Medicine have reanalyzed the findings of two historic pediatric HIV vaccine trials with encouraging results. The vaccines had in fact triggered an antibody response -- now known to be associated with protection in adults -- that was previously unrecognized in the infants studied in the 1990s.

22-Aug-2014 8:45 AM EDT
Surgical Complications of DBS No Higher Risk for Older Parkinson’s Patients
Duke Health

Implantating deep brain stimulation devices poses no greater risk of complications to older patients than it does to younger patients with Parkinson’s disease, researchers at Duke Medicine report.

6-Aug-2014 2:35 PM EDT
Gut Flora Influences HIV Immune Response
Duke Health

Normal microorganisms in the intestines appear to play a pivotal role in how the HIV virus foils a successful attack from the body’s immune system, according to new research from Duke Medicine.

30-Jul-2014 2:00 PM EDT
Molecule Enhances Copper’s Lethal Punch Against Microbes
Duke Health

Harnessing a natural process in the body that pumps lethal doses of copper to fungi and bacteria shows promise as a new way to kill infectious microbes, a team of scientists at Duke University report.

21-Jul-2014 1:00 PM EDT
Mechanism Found for Development of Protective HIV Antibodies
Duke Health

Scientists at Duke Medicine have found an immunologic mechanism that makes broadly neutralizing antibodies in people who are HIV-1 infected.

Released: 22-Jul-2014 9:35 AM EDT
Study Compares Cost-Effectiveness of Weight-Loss Programs and Drugs
Duke Health

In a cost-effectiveness analysis of commercial diet programs and pills, the Weight Watchers program and the drug Qsymia showed the best value for the money. The Jenny Craig regimen generated the greatest weight loss, but was also the most expensive option tested, according to researchers at Duke-National University of Singapore (NUS) Graduate Medical School.

Released: 11-Jul-2014 12:05 AM EDT
Omega 3 Fatty Acids Lessen Severity of Osteoarthritis in Mice
Duke Health

Mice consuming a supplement of omega 3 fatty acids had healthier joints than those fed diets high in saturated fats and omega 6 fatty acids, according to Duke Medicine researchers.

Released: 8-Jul-2014 4:00 PM EDT
New Technologies Fuel Patient Participation and Data Collection in Research
Duke Health

The changing dynamic of health studies driven by “big data” research projects will empower patients to become active participants who provide real-time information such as symptoms, side effects and clinical outcomes, according to researchers at Duke Medicine.

Released: 24-Jun-2014 8:05 AM EDT
DCRI and Industry Collaboration Promotes Open Data Access
Duke Health

Duke University, through its Duke Clinical Research Institute (DCRI), announced this week it has entered into a novel collaboration with Bristol-Myers Squibb (BMS) to promote open access to clinical information from company-sponsored studies.

Released: 23-Jun-2014 10:00 AM EDT
BPA Stimulates Growth of Breast Cancer Cells, Diminishes Effect of Treatment
Duke Health

Bisphenol A (BPA), a chemical commonly used in plastics, appears to increase the proliferation of breast cancer cells, according to Duke Medicine researchers presenting at an annual meeting of endocrine scientists.

16-Jun-2014 12:00 PM EDT
Air Pollution Controls Linked to Lower Death Rates in North Carolina
Duke Health

National and state air pollution controls that went into effect in the early 1990s coincide with decreasing death rates from emphysema, asthma and pneumonia among people in North Carolina, according to a study led by Duke University researchers.

19-Jun-2014 12:00 PM EDT
Architecture of Signaling Proteins Enhances Knowledge of Key Receptors
Duke Health

A team of scientists from Duke Medicine, the University of Michigan and Stanford University has determined the underlying architecture of a cellular signaling complex involved in the body’s response to stimuli such as light and pain.

   
11-Jun-2014 1:25 PM EDT
Heparin Derivative Suppresses Neuroblastoma Tumor Growth
Duke Health

Researchers at Duke Medicine have identified a new strategy for treating neuroblastoma using a modified version of heparin, a century-old injectable drug that thins the blood to prevent clots from forming. The study, conducted in mice and published June 17, 2014, in the Journal of Clinical Investigation, found that when heparin is altered to remove its blood-thinning properties, it can suppress and shrink neuroblastoma tumors without causing severe bleeding.

13-Jun-2014 8:00 AM EDT
Combining Treatments Boosts Some Smokers’ Ability to Quit
Duke Health

Combining two smoking cessation therapies is more effective than using just one for male and highly nicotine-dependent smokers who weren't initially helped by the nicotine patch, according to researchers at Duke Medicine.

Released: 9-Jun-2014 4:00 PM EDT
Lifetime Cancer Risk from Heart Imaging Low for Most Children, but Rises with More Complex Tests
Duke Health

Children with heart disease are exposed to low levels of radiation during X-rays, which do not significantly raise their lifetime cancer risk. However, children who undergo repeated complex imaging tests that deliver higher doses of radiation may have a slightly increased lifetime risk of cancer, according to researchers at Duke Medicine.

2-Jun-2014 9:30 AM EDT
One and Done: New Antibiotic Could Provide Single-Dose Option
Duke Health

In the battle against stubborn skin infections, including methicillin-resistant Staphylococcus aureus (MRSA), a new single-dose antibiotic is as effective as a twice-daily infusion given for up to 10 days, according to a large study led by Duke Medicine researchers.

Released: 4-Jun-2014 1:00 PM EDT
New Diagnostic Imaging Techniques Deemed Safe in Simulations
Duke Health

Gamma and neutron imaging offer possible improvements over existing techniques such as X-ray or CT, but their safety is not yet fully understood. Using computer simulations, imaging the liver and breast with gamma or neutron radiation was found to be safe, delivering levels of radiation on par with conventional medical imaging, according to researchers at Duke Medicine.

Released: 4-Jun-2014 10:00 AM EDT
Registry for Fatal Lung Disease Aims to Speed Improvements in Care
Duke Health

Duke Clinical Research Institute (DCRI) has launched a patient registry to help researchers and clinicians identify, manage and study people who have a progressive lung disease called idiopathic pulmonary fibrosis. The registry, a joint effort by DCRI and Boehringer Ingelheim Pharmaceuticals, Inc., is the first multi-center registry in the United States focused specifically on idiopathic pulmonary fibrosis.

29-May-2014 2:50 PM EDT
Implanted Heart Device Linked to Increased Survival
Duke Health

Implantable cardioverter defibrillators (ICDs) are associated with improved survival among heart failure patients whose left ventricles only pump 30 to 35 percent of blood out of the heart with each contraction, according to a study from the Duke Clinical Research Institute.

29-May-2014 10:00 AM EDT
Newly Identified Brain Cancer Mutation Will Aid Drug Development
Duke Health

A collaborative effort between Duke Medicine researchers and neurosurgeons and scientists in China has produced new genetic insights into a rare and deadly form of childhood and young adult brain cancer called brainstem glioma.

Released: 30-May-2014 2:00 PM EDT
Stopping Statins May Benefit Terminally Ill Patients
Duke Health

People in the late stages of cancer and other terminal illnesses are not only unharmed by discontinuing statins for cholesterol management, they may benefit, according to a study presented Friday by researchers at Duke Medicine representing a national research network.

14-May-2014 5:40 PM EDT
Non-Invasive Lithotripsy Leads to More Treatment for Kidney Stones
Duke Health

When it comes to treating kidney stones, less invasive may not always be better, according to new research from Duke Medicine. In a direct comparison of shock wave lithotripsy vs. ureteroscopy – the two predominant methods of removing kidney stones – researchers found that ureteroscopy resulted in fewer repeat treatments.

8-May-2014 10:00 AM EDT
Bullying May Have Long-Term Health Consequences
Duke Health

Bullied children may experience chronic, systemic inflammation that persists into adulthood, while bullies may actually reap health benefits of increasing their social status through bullying, according to researchers at Duke Medicine.

6-May-2014 2:00 PM EDT
ADHD Treatment Associated with Lower Smoking Rates
Duke Health

Treating attention deficit hyperactivity disorder (ADHD) with stimulant medication may reduce smoking risk, especially when medication is taken consistently, according to an analysis led by researchers at Duke Medicine.

2-May-2014 4:15 PM EDT
Duke-Led Team Clarifies Use of Anti-Fungal Drug for Premature Infants
Duke Health

In most circumstances, extremely premature babies should not be given a drug to prevent a potentially fatal fungal infection, according to findings by a Duke Medicine-led research team.

Released: 1-May-2014 3:00 PM EDT
Statin Use Associated with Reduced Risk of Prostate Cancer Recurrence
Duke Health

-- Men who begin taking statins after prostate cancer surgery are less likely to have a recurrence of their cancer, according to a retrospective analysis led by researchers at Duke Medicine.

25-Apr-2014 8:00 AM EDT
Complications From Kidney Stone Treatments Are Common And Costly
Duke Health

Despite their overall low risk, procedures to treat kidney stones lead to complications that require hospitalization or emergency care for one in seven patients, according to researchers at Duke Medicine.

Released: 24-Apr-2014 11:00 AM EDT
New Approach for Surgery Patients Cuts Hospital Stays and Costs
Duke Health

Changes in managing patients before, during and after colorectal surgery cut hospital stays by two days and reduced readmission rates, according to researchers who led a study of the approach at Duke University Hospital.

7-Apr-2014 2:00 PM EDT
A Bad Penny: Cancer’s Thirst For Copper Can Be Targeted
Duke Health

Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.

3-Apr-2014 10:00 AM EDT
Over a Lifetime, Childhood Obesity Costs $19,000 Per Child
Duke Health

Childhood obesity comes with an estimated price tag of $19,000 per child when comparing lifetime medical costs to those of a normal weight child, according to an analysis led by researchers at the Duke Global Health Institute and Duke-NUS Graduate Medical School in Singapore.

Released: 1-Apr-2014 12:00 PM EDT
Common Molecular Defect Offers Treatment Hope for Group of Rare Disorders
Duke Health

Duke Medicine researchers studying tiny, antennae-like structures called cilia have found a potential way to ease some of the physical damage of numerous genetic disorders that result when these essential cellular components are defective.

Released: 29-Mar-2014 5:00 PM EDT
High Blood Pressure Increases Risk of Stroke for Atrial Fibrillation Patients
Duke Health

Poor blood pressure control among patients with atrial fibrillation is associated with a 50-percent increased risk of stroke, according to an analysis presented by Duke Medicine researchers.

27-Mar-2014 11:20 AM EDT
Relaxed Blood Pressure Guidelines Cut Millions from Needing Medication
Duke Health

New guidelines that ease the recommended blood pressure could result in 5.8 million U.S. adults no longer needing hypertension medication, according to an analysis by Duke Medicine researchers.

18-Mar-2014 11:00 AM EDT
New Guidelines Deem 13 Million More Americans Eligible for Statins
Duke Health

New guidelines for using statins to treat high cholesterol and prevent cardiovascular disease are projected to result in 12.8 million more U.S. adults taking the drugs, according to a research team led by Duke Medicine scientists.

Released: 19-Mar-2014 4:00 PM EDT
Past HIV Vaccine Trials Reveal New Path to Success
Duke Health

A multi-national research team led by Duke Medicine scientists has identified a subclass of antibodies associated with an effective immune response to an HIV vaccine.

13-Mar-2014 1:00 PM EDT
One in Three Patients with Bloodstream Infections Given Inappropriate Therapy
Duke Health

Growing drug resistance, a high prevalence of S. aureus bacteria and ineffective antibiotics prescribed to one in three patients are among the challenges facing community hospitals in treating patients with serious bloodstream infections, according to researchers at Duke Medicine.

11-Mar-2014 2:00 PM EDT
Contagious Yawning May Not Be Linked to Empathy; Still Largely Unexplained
Duke Health

While previous studies have suggested a connection between contagious yawning and empathy, new research from the Duke Center for Human Genome Variation finds that contagious yawning may decrease with age and is not strongly related to variables like empathy, tiredness and energy levels.

5-Mar-2014 10:00 AM EST
Plaques Detected in Brain Scans Forecast Cognitive Impairment
Duke Health

Brain imaging using radioactive dye can detect early evidence of Alzheimer's disease that may predict future cognitive decline among adults with mild or no cognitive impairment, according to a 36-month follow-up study led by Duke Medicine.

6-Mar-2014 3:00 PM EST
Unique Individual Demonstrates Desired Immune Response to HIV Virus
Duke Health

One person’s unique ability to fight HIV has provided key insights into an immune response that researchers now hope to trigger with a vaccine, according to findings reported by a team that includes Duke Medicine scientists.

28-Feb-2014 4:40 PM EST
Blasts May Cause Brain Injury Even Without Symptoms
Duke Health

Veterans exposed to explosions who do not report symptoms of traumatic brain injury (TBI) may still have damage to the brain's white matter comparable to veterans with TBI, according to researchers at Duke Medicine and the U.S. Department of Veterans Affairs.

20-Feb-2014 11:00 AM EST
Duke Teams Set Treatment Priorities in New National Research Effort
Duke Health

Treatment regimens often evolve without strong scientific evidence of their benefits and drawbacks, particularly in comparison to other drugs or approaches. Now Duke Medicine is participating in a large national initiative aiming to fill in that missing information.

Released: 17-Feb-2014 2:00 PM EST
Natural Compound Attacks HER2 Positive Breast Cancer Cells
Duke Health

A common compound known to fight lymphoma and skin conditions actually has a second method of action that makes it particularly deadly against certain aggressive breast tumors, researchers at Duke Medicine report.

Released: 10-Feb-2014 11:45 AM EST
Young, Unvaccinated Adults Account for Severest Flu Cases
Duke Health

A snapshot of patients who required care at Duke University Hospital during this year’s flu season shows that those who had not been vaccinated had severe cases and needed the most intensive treatment.

Released: 5-Feb-2014 10:00 AM EST
Non-Traditional Risk Factors Illuminate Racial Disparities in Type 2 Diabetes
Duke Health

Two surprising risk factors – diminished lung function and low serum potassium levels - appear to have nearly the same impact as obesity in explaining why African-Americans are disproportionately prone to developing type 2 diabetes, researchers at Duke Medicine report.



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