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Released: 1-Mar-2017 3:05 PM EST
Gene Therapy to Fight a Blood Cancer Succeeds in Major Study
Yale Cancer Center/Smilow Cancer Hospital

An experimental gene therapy that turns a patient's own blood cells into cancer killers worked in a major study. Article by the Associated Press.

Released: 27-Feb-2017 12:05 PM EST
Limiting Lung Cancer’s Spread and Growth in the Brain
Yale Cancer Center/Smilow Cancer Hospital

Led by associate professor of pathology and Yale Cancer Center member Don Nguyen, PhD, the researchers analyzed RNA from patients with disease that was limited to the lungs as well as cancers that had spread.

Released: 27-Feb-2017 11:05 AM EST
Professor Susan Baserga Selected as Finalist for the 2017 Connecticut Technology Council Women of Innovation Program
Yale Cancer Center/Smilow Cancer Hospital

Susan Baserga selected as a finalist for the 2017 Connecticut Technology Council Women of Innovation program

Released: 27-Feb-2017 11:05 AM EST
When Cancer Treatments Do More Harm Than Good
Yale Cancer Center/Smilow Cancer Hospital

Dr. Cary Gross, a professor of medicine and cancer researcher at Yale University School of Medicine discusses his 80-year-old father's diagnosis with Hodgkin’s disease.

Released: 22-Feb-2017 12:05 PM EST
Four Faculty Elected to Connecticut Academy of Science and Engineering
Yale Cancer Center/Smilow Cancer Hospital

Four Yale School of Medicine researchers have been elected to the prestigious Connecticut Academy of Science and Engineering (CASE).

Released: 22-Feb-2017 12:05 PM EST
11 From Yale Elected to Connecticut Academy of Science and Engineering
Yale Cancer Center/Smilow Cancer Hospital

The Connecticut Academy of Science and Engineering has elected 24 of the state’s leading experts in science, engineering, and technology to membership in the academy, including 11 new members from Yale.

Released: 20-Feb-2017 10:05 AM EST
What Turns Benign Central Nervous System Tumors Deadly
Yale Cancer Center/Smilow Cancer Hospital

In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40% chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors.

Released: 15-Feb-2017 1:30 PM EST
Study Points to Potential New Brain Cancer Treatment
Yale Cancer Center/Smilow Cancer Hospital

A recent Yale study may have found a new way to fight brain cancer.

Released: 15-Feb-2017 1:05 PM EST
Genome Analysis Helps Keep Deadly Brain Cancer at Bay for Five Years
Yale Cancer Center/Smilow Cancer Hospital

An analysis of a patient’s deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.

Released: 15-Feb-2017 1:05 PM EST
'Explosive Growth’ of Interventional Oncology Prompts Formation of New Society
Yale Cancer Center/Smilow Cancer Hospital

The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission.

Released: 8-Feb-2017 11:05 AM EST
Immunotherapy May Need to Have Its Own Value Model
Yale Cancer Center/Smilow Cancer Hospital

Immunotherapy has been a game changer for the oncology field, but typical models used to assess the value of cancer treatments don’t take into account the unique characteristics of this therapy, according to experts at the 2016 annual meeting of the Society for Immunotherapy of Cancer (SITC).

Released: 6-Feb-2017 12:05 PM EST
Yale Study: 1 in 4 Teen E-Cigarette Users Have Tried 'Dripping'
Yale Cancer Center/Smilow Cancer Hospital

Yale researchers found in a study that one in four high schoolers who use electronic cigarettes are inhaling vapors produced by dripping e-liquids directly onto heating coils, instead of inhaling from the e-cigarette mouthpiece, possibly increasing exposure to toxins and nicotine.

Released: 3-Feb-2017 12:05 PM EST
Why Doctors May Keep a Patient Awake for Brain Surgery
Yale Cancer Center/Smilow Cancer Hospital

A rare look at brain surgery with the patient alert and awake at Smilow Cancer Hospital at Yale-New Haven.

Released: 2-Feb-2017 1:05 PM EST
Yale Scientists Identify Key Defect in Brain Tumor Cells
Yale Cancer Center/Smilow Cancer Hospital

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

Released: 30-Jan-2017 12:05 PM EST
Clue to How Cancer Cells Spread
Yale Cancer Center/Smilow Cancer Hospital

In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

Released: 26-Jan-2017 3:05 PM EST
Dr. Harold Tara Appointed Medical Director of Smilow Care Centers in Trumbull & Fairfield
Yale Cancer Center/Smilow Cancer Hospital

Dr. Harold Tara Appointed Medical Director of Smilow Care Centers in Trumbull & Fairfield

Released: 12-Jan-2017 12:05 PM EST
NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations
Yale Cancer Center/Smilow Cancer Hospital

Recognizing a critical need to improve national vaccination rates for the human papillomavirus (HPV), Yale Cancer Center has again united with each of the 69 National Cancer Institute (NCI)-designated cancer centers in issuing a joint statement in support of recently revised recommendations from the Centers for Disease Control and Prevention (CDC).

Released: 6-Jan-2017 2:05 PM EST
National Organization of Italian American Women Will Honor Dr. Pat LoRusso
Yale Cancer Center/Smilow Cancer Hospital

The Connecticut Region of the National Organization of Italian American Women (NOIAW) will honor three of Connecticut’s most prominent and pioneering women at its eighth annual Epiphany Celebration brunch and silent auction event, on Sunday, January 15, 2017, at the New Haven Lawn Club in New Haven, CT.

Released: 6-Jan-2017 10:05 AM EST
Unexpected Role for Epigenetic Enzymes in Cancer
Yale Cancer Center/Smilow Cancer Hospital

In a Yale-led study, Qin Yan and his co-authors focused on a family of enzymes — known as KDM5 — that have been shown in previous studies to be involved in cancer cell growth and spreading.

Released: 6-Jan-2017 10:05 AM EST
Aspirin Use Found to Lower Risk of Pancreatic Cancer
Yale Cancer Center/Smilow Cancer Hospital

The regular use of aspirin lowers the risk for pancreatic cancer by almost 50 percent, a new study in China led by the Yale School of Public Health finds.

Released: 6-Jan-2017 10:05 AM EST
Lung Cancer Patients May Benefit From Delayed Chemotherapy After Surgery
Yale Cancer Center/Smilow Cancer Hospital

A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers.

26-Dec-2016 4:00 PM EST
Reducing Radiation Successfully Treats HPV-Positive Oropharynx Cancers and Minimizes Side Effects
Yale Cancer Center/Smilow Cancer Hospital

Human papillomavirus-positive oropharynx cancers (cancers of the tonsils and back of the throat) are on rise. After radiation treatment, patients often experience severe, lifelong swallowing, eating, and nutritional issues. However, new clinical trial research shows reducing radiation for some patients with HPV-associated oropharyngeal squamous cell carcinomas can maintain high cure rates while sparing some of these late toxicities.

22-Dec-2016 9:00 AM EST
Researchers Identify Heterogeneity of Tissue Resident Memory T Cells as Targets of Checkpoint Therapies
Yale Cancer Center/Smilow Cancer Hospital

Researchers at Yale Cancer Center and Yale Medicine have identified the critical target of new immune-checkpoint therapies: subsets of immune cells called tissue resident memory (TRM) T cells. In the same research, scientists also found that individual metastatic cancer lesions contain unique sets of TRM cells.

Released: 20-Dec-2016 10:05 AM EST
Regular Aspirin Use May Reduce Risk for Pancreatic Cancer
Yale Cancer Center/Smilow Cancer Hospital

Regular use of aspirin by people living in Shanghai, China, was associated with decreased risk for developing pancreatic cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Released: 13-Dec-2016 2:00 PM EST
Study Identifies Subtype of Triple Negative Breast Cancer That Responds Better to Chemotherapy
Yale Cancer Center/Smilow Cancer Hospital

Researchers at Yale Cancer Center have identified a new subtype of triple negative breast cancer that shows significantly improved response to chemotherapy.

5-Dec-2016 7:30 PM EST
Alternative Option to Intensive Chemotherapy for Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)
Yale Cancer Center/Smilow Cancer Hospital

A Yale Cancer Center team has evaluated the use of hypomethylating agents in patients suffering from Acute Myeloid Leukemia (AML) who were resistant to treatment with intensive chemotherapy.

Released: 5-Dec-2016 2:05 PM EST
Immune System, Unleashed by Cancer Therapies, Can Attack Organs
Yale Cancer Center/Smilow Cancer Hospital

Doctors at Yale believe immunotherapy is causing a new type of acute-onset diabetes, with at least 17 cases so far.

Released: 5-Dec-2016 12:05 PM EST
The Economic Burden of Treatment for Diffuse Large B-Cell Lymphoma
Yale Cancer Center/Smilow Cancer Hospital

In a recent study, a Yale Cancer Center team confirmed expectations of higher healthcare utilization and costs with relapsed Diffuse Large B-Cell Lymphoma (DLBCL).

Released: 2-Dec-2016 11:05 AM EST
American Cancer Society Approves New Research and Training Grants at Yale University
Yale Cancer Center/Smilow Cancer Hospital

The American Cancer Society (ACS), the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding for three new research grants totaling over $1.7 million to investigators at Yale University.

Released: 2-Dec-2016 10:05 AM EST
New Drug for Patients with Late-Stage Lung Cancer
Yale Cancer Center/Smilow Cancer Hospital

A new drug has been approved by the FDA in the fight against lung cancer. Tecentriq is being used by patients like Cornelius Bresnan, who had late-stage cancer.

Released: 21-Nov-2016 10:05 AM EST
Lung-MAP Clinical Trial is helping Patients with Lung Cancer
Yale Cancer Center/Smilow Cancer Hospital

Lung-MAP (SWOG S1400) is a multi-drug, multi-sub-study, biomarker-driven squamous cell lung cancer clinical trial that uses state-of-the-art genomic profiling to match patients to sub-studies testing investigational treatments that may target the genomic alterations, or mutations, found to be driving the growth of their cancer.

Released: 21-Nov-2016 9:05 AM EST
Dr. Roy Herbst to Be Honored for Lifetime Achievement
Yale Cancer Center/Smilow Cancer Hospital

Professor Roy S. Herbst, M.D., Ph.D., Yale University, New Haven, will be recognized by The International Association for the Study of Lung Cancer with a Distinguished Award at the IASLC 17th World Conference on Lung Cancer in Vienna, Austria.

Released: 18-Nov-2016 11:05 AM EST
Optimizing Frontline Immunotherapy in NSCLC
Yale Cancer Center/Smilow Cancer Hospital

Immunotherapy continues to revolutionize the field of non–small cell lung cancer (NSCLC), with researchers now focusing on the optimal use of immune agents in the frontline setting.

Released: 18-Nov-2016 11:05 AM EST
Weight Loss Can Help Cancer Survivors Reduce Risk
Yale Cancer Center/Smilow Cancer Hospital

New data presented at a cancer conference suggests that more than three in five Australian breast cancer survivors are overweight or obese – and that it’s likely to increase their risk of cancer returning.

Released: 28-Oct-2016 9:05 AM EDT
FDA Approves Keytruda for First-Line Treatment of PD-L1–Expressing Metastatic NSCLC
Yale Cancer Center/Smilow Cancer Hospital

The FDA granted approval to pembrolizumab for the first-line treatment of patients with metastatic non–small cell lung cancer whose tumors express programmed death ligand-1 as determined by an FDA–approved test.

Released: 28-Oct-2016 9:05 AM EDT
Pembrolizumab in HNSCC Only Scratches the Surface of Immunotherapy Potential
Yale Cancer Center/Smilow Cancer Hospital

The recent approval of pembrolizumab (Keytruda) in recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) following progression on a platinum-based chemotherapy was a significant advancement for the disease. However, Barbara A. Burtness, MD, said, the approval of the PD-1 inhibitor only scratches the surface of the potential of immunotherapies in head and neck cancer.



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