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Released: 22-May-2013 5:10 PM EDT
Depression Linked to Telomere Enzyme, Aging, Chronic Disease
University of California, San Francisco (UCSF)

The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain.

14-May-2013 4:00 PM EDT
Stem-Cell-Based Strategy Boosts Immune System in Mice
University of California, San Francisco (UCSF)

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

8-May-2013 3:00 PM EDT
Early Formula Use Helps Some Mothers Breastfeed Longer
University of California, San Francisco (UCSF)

Recent public health efforts have focused extensively on reducing the amount of formula babies are given in the hospital after birth. But in the first randomized trial of its kind, researchers at UC San Francisco have found that giving small amounts of formula in the first few days of life to infants experiencing high levels of early weight loss actually can increase the length of time their mothers end up breastfeeding.

Released: 8-May-2013 12:05 AM EDT
New Prostate Cancer Test Improves Risk Assessment
University of California, San Francisco (UCSF)

A new genomic test for prostate cancer can help predict whether men are more likely to harbor an aggressive form of the disease, according to a new UC San Francisco study. The test, which improves risk assessment when patients are first diagnosed, can also aid in determining which men are suitable for active surveillance – a way of managing the disease without direct treatment.

Released: 3-May-2013 5:15 PM EDT
Human Brain Cells Developed in Lab, Grow in Mice
University of California, San Francisco (UCSF)

A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat people with Parkinson’s disease, epilepsy, and possibly even Alzheimer’s disease, as well as and complications of spinal cord injury such as chronic pain and spasticity.

Released: 3-May-2013 5:00 PM EDT
Epilepsy Cured in Mice Using Brain Cells
University of California, San Francisco (UCSF)

Epilepsy that does not respond to drugs can be halted in adult mice by transplanting a specific type of cell into the brain, UC San Francisco researchers have discovered, raising hope that a similar treatment might work in severe forms of human epilepsy.

Released: 2-May-2013 5:00 PM EDT
Tick-Borne Lone Star Virus Identified through New Super-Fast Gene Sequencing
University of California, San Francisco (UCSF)

The tick-borne Lone Star virus has been conclusively identified as part of a family of other tick-borne viruses called bunyaviruses, which often cause fever, respiratory problems and bleeding, according to new research led by scientists at UC San Francisco (UCSF).

29-Apr-2013 4:00 PM EDT
Genetic Mutation Linked with Typical Form of Migraine
University of California, San Francisco (UCSF)

A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.

29-Apr-2013 3:00 PM EDT
Antidepressants Linked with Increased Risks After Surgery
University of California, San Francisco (UCSF)

Selective serotonin reuptake inhibitors (SSRIs) – among the most widely prescribed antidepressant medications – are associated with increased risk of bleeding, transfusion, hospital readmission and death when taken around the time of surgery, according to an analysis led by researchers at UC San Francisco and Baystate Medical Center in Springfield, Mass.

29-Apr-2013 3:30 PM EDT
Surgery for Nonfatal Skin Cancers Might Not Be Best for Elderly Patients
University of California, San Francisco (UCSF)

Surgery is often recommended for skin cancers, but older, sicker patients can endure complications as a result and may not live long enough to benefit from the treatment.

Released: 19-Apr-2013 4:55 PM EDT
Muscle Repair After Injury Helped by Fat-Forming Cells
University of California, San Francisco (UCSF)

UC San Francisco scientists have discovered that muscle repair requires the action of two types of cells better known for causing inflammation and forming fat. 

Released: 18-Apr-2013 2:30 PM EDT
Smoking from Hookah Not a Harmless Alternative to Cigarettes
University of California, San Francisco (UCSF)

Smoking tobacco through a hookah is a pastime gaining popularity among the college crowd, but many of them mistakenly believe that using the fragrant water pipe is less harmful than smoking cigarettes.

12-Apr-2013 5:00 PM EDT
Genetic Markers Linked To the Development of Lymphedema in Breast Cancer Survivors
University of California, San Francisco (UCSF)

A new UCSF study has found a clear association between certain genes and the development of lymphedema, a painful and chronic condition that often occurs after breast cancer surgery and some other cancer treatments.

11-Apr-2013 12:00 PM EDT
Routine EKG Finding Could Signal Serious Heart Problem
University of California, San Francisco (UCSF)

A common test that records the heart’s electrical activity could predict potentially serious cardiovascular illness, according to a UC San Francisco-led study.

12-Apr-2013 11:35 AM EDT
Autism Model in Mice Linked With Genetics
University of California, San Francisco (UCSF)

For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals’ chromosomes.

Released: 15-Apr-2013 4:40 PM EDT
Brain Development Is Guided by Junk DNA that Isn’t Really Junk
University of California, San Francisco (UCSF)

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

1-Apr-2013 7:00 PM EDT
Will Cell Therapy Become a “Third Pillar” of Medicine?
University of California, San Francisco (UCSF)

Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. They outlined their vision of cell-based therapeutics as a “third pillar of medicine” in an article published online April 3 in Science Translational Medicine.

2-Apr-2013 4:00 PM EDT
Laser Light Zaps Away Cocaine Addiction
University of California, San Francisco (UCSF)

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they can wipe away addictive behavior in rats – or conversely turn non-addicted rats into compulsive cocaine seekers.

Released: 22-Mar-2013 4:15 PM EDT
Li Ka Shing Gift Supports UCSF Quest for Precision Medicine
University of California, San Francisco (UCSF)

The Li Ka Shing Foundation has pledged $2 million to support UC San Francisco’s efforts to advance Precision Medicine, an emerging field aimed at revolutionizing medical research and patient care.

Released: 21-Mar-2013 12:50 PM EDT
UCSF Appoints New Dean of Nation’s Top Pharmacy School
University of California, San Francisco (UCSF)

UC San Francisco has named a highly accomplished pharmacist and clinical scientist, B. Joseph Guglielmo, PharmD, to lead the nation’s premier School of Pharmacy, continuing the school’s focus on shaping the course of the therapeutic sciences, pharmacy education, patient care, and health policy.

Released: 20-Mar-2013 4:00 PM EDT
Brain Mapping Reveals Neurological Basis of Decision-Making in Rats
University of California, San Francisco (UCSF)

Scientists at UC San Francisco have discovered how memory recall is linked to decision-making in rats, showing that measurable activity in one part of the brain occurs when rats in a maze are playing out memories that help them decide which way to turn. The more they play out these memories, the more likely they are to find their way correctly to the end of the maze.

Released: 20-Mar-2013 2:00 PM EDT
Charges For Emergency Room Visits Often Based On Incorrect Assumptions
University of California, San Francisco (UCSF)

Visits to the ER are not always for true medical emergencies – and some policymakers have been fighting the problem by denying or limiting payments if the patient’s diagnosis upon discharge is for “nonemergency” conditions.

Released: 19-Mar-2013 7:00 PM EDT
Online Cardiovascular Study to Help Predict and Prevent Heart Disease
University of California, San Francisco (UCSF)

A UC San Francisco team has developed an ambitious online cardiovascular study using mobile smartphones, with the goal of enrolling one million people from all over the world to improve heart health.

Released: 19-Mar-2013 2:30 PM EDT
Biennial Mammograms Best After 50, Even For Women with Dense Breasts
University of California, San Francisco (UCSF)

Screening for breast cancer every two years appears just as beneficial as yearly mammograms for women ages 50 to 74, with significantly fewer “false positives” – even for women whose breasts are dense or who use hormone therapy for menopause.

Released: 13-Mar-2013 1:15 PM EDT
Immune Cells Cluster And Communicate ‘Like Bees,’ Researcher Says
University of California, San Francisco (UCSF)

The immune system’s T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new study by scientists at UC San Francisco.

   
Released: 12-Mar-2013 2:00 PM EDT
UCSF Ranked Among Top Medical Schools In Nation By U.S. News
University of California, San Francisco (UCSF)

UC San Francisco’s School of Medicine ranked fourth nationwide in both research and primary care education this year, according to a new survey conducted by U.S. News & World Report.

Released: 7-Mar-2013 4:55 PM EST
Disease Knowledge May Advance Faster with CRISPR Gene Probing Tool
University of California, San Francisco (UCSF)

Scientists at UC San Francisco have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs and tissues.

Released: 5-Mar-2013 6:00 PM EST
Top Patient Safety Strategies Detailed In New AHRQ Report
University of California, San Francisco (UCSF)

The Agency for Healthcare Research and Quality (AHRQ) has released a new report, Making Health Care Safer II, which identifies the top 10, evidence-based patient safety strategies available to clinicians.

4-Mar-2013 1:10 PM EST
New Clinical Tool Assesses Health Risks for Older Adults
University of California, San Francisco (UCSF)

A UC San Francisco team has developed a tool that can help determine – and perhaps influence – senior citizens’ 10-year survivability rates.

1-Mar-2013 2:30 PM EST
Parkinson’s Disease Brain Rhythms Detected
University of California, San Francisco (UCSF)

A team of scientists and clinicians at UC San Francisco has discovered how to detect abnormal brain rhythms associated with Parkinson’s by implanting electrodes within the brains of people with the disease.

Released: 28-Feb-2013 4:20 PM EST
‘Rain Man’-like Brains Mapped at UCSF
University of California, San Francisco (UCSF)

Combining hospital MRIs with the mathematical tool known as network analysis, a group of researchers at UC San Francisco and UC Berkeley have mapped the three-dimensional global connections within the brains of seven adults who have genetic malformations that leave them without the corpus callosum, which connects the left and right sides of the brain.

26-Feb-2013 10:40 PM EST
How Much Will I Be Charged?
University of California, San Francisco (UCSF)

It’s a basic, reasonable question: How much will this cost me? For patients in the emergency room, the answer all too often is a mystery.

Released: 26-Feb-2013 2:40 PM EST
Electronic Health Communications Often Unavailable to Lower Income Patients
University of California, San Francisco (UCSF)

Lower-income patients want to communicate electronically with their doctors, but the revolution in health care technology often is not accessible to them, due to inadequate health information services within the health care clinics they frequent, according to a survey by UC San Francisco researchers.

Released: 20-Feb-2013 7:00 PM EST
New Website Helps Parents Manage Children’s Pain After Surgery
University of California, San Francisco (UCSF)

When a young child has surgery, parents rely on doctors and nurses for advice on how to prepare and support children during the procedure and immediately afterwards. But once that child gets home, parents are left with little guidance on how to best help their children cope with pain.

20-Feb-2013 12:00 PM EST
Secrets of Human Speech Uncovered
University of California, San Francisco (UCSF)

A team of researchers at UC San Francisco has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.

12-Feb-2013 8:00 PM EST
Gene Invaders Are Stymied by a Cell’s Genome Defense
University of California, San Francisco (UCSF)

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that helps protect a cell’s genes against these DNA interlopers.

12-Feb-2013 12:00 PM EST
California’s Tobacco Control Program Generates Huge Health Care Savings
University of California, San Francisco (UCSF)

Over a span of nearly 20 years, California’s tobacco control program cost $2.4 billion and reduced health care costs by $134 billion, according to a new study by UC San Francisco.

Released: 12-Feb-2013 11:00 AM EST
UCSF-Safeway Pharmacy Alliance Aims to Help Customers Quit Smoking
University of California, San Francisco (UCSF)

The UCSF School of Pharmacy has partnered with Safeway Inc. to help Safeway customers quit smoking, by connecting them with specially trained pharmacists to learn about smoking-cessation programs and other resources.

Released: 11-Feb-2013 7:00 PM EST
Parents of Teen Girls More Accepting of Birth Control Pills Than Other Contraceptive Methods
University of California, San Francisco (UCSF)

Parents are more accepting of their teenage daughters using birth control pills than any other form of contraception, including condoms, according to a recent study from UC San Francisco (UCSF). The most effective contraceptive methods, the implant – a matchstick-sized rod that is inserted in the arm to prevent pregnancy – and the intrauterine device (IUD), were acceptable to a minority of parents.

1-Feb-2013 3:15 PM EST
Maternal Exposure to Outdoor Air Pollution Associated with Low Birth Weights Worldwide
University of California, San Francisco (UCSF)

Mothers who are exposed to particulate air pollution of the type emitted by vehicles, urban heating and coal power plants are significantly more likely to bear children of low birth weight, according to an international study led by co-principal investigator Tracey J. Woodruff, PhD, MPH, professor of obstetrics and gynecology and reproductive sciences at UC San Francisco along with Jennifer Parker, PhD, of the National Center for Health Statistics, Centers for Disease Control and Prevention.

1-Feb-2013 5:00 PM EST
Mammogram Every Two Years Has Same Benefit As Yearly Mammogram for Older Women
University of California, San Francisco (UCSF)

Among older women, getting a mammogram every two years was just as beneficial as getting a mammogram annually, and led to significantly fewer false positive results, according to a study led by UC San Francisco.

25-Jan-2013 3:05 PM EST
Early Menopause May Occur In Women with BRCA Gene
University of California, San Francisco (UCSF)

Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even briefer reproductive window and possibly a higher risk of infertility, according to a study led by researchers at UC San Francisco.

25-Jan-2013 4:45 PM EST
In Breast Cancer Metastasis, Researchers Identify Possible Drug Target
University of California, San Francisco (UCSF)

The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries point to possible targets for therapy.

Released: 22-Jan-2013 5:00 PM EST
A Call to Prevent Unsafe High-Risk Medical Devices from Reaching the Marketplace
University of California, San Francisco (UCSF)

Technological advancements in medicine have allowed patients suffering from musculoskeletal conditions such as hip and knee pain to regain mobility and live relatively pain-free. But some “high risk” surgical devices that have been approved by the U.S. Food and Drug Administration (FDA) are not required to go through clinical trials, where a product is tested to determine its safety and effectiveness.

Released: 18-Jan-2013 2:35 PM EST
Complex Spinal Surgeries with Two Attending Physicians, Instead of One, Benefit Patients
University of California, San Francisco (UCSF)

Two heads are better than one, as the saying goes – and a new study by a duo at the University of California, San Francisco (UCSF) demonstrates how having two attending surgeons in the operating room during spinal surgeries can benefit patients in multiple ways.

Released: 18-Jan-2013 8:00 AM EST
Abortions Are Safe When Performed By Nurses Practitioners, Physician Assistants and Certified Nurse Midwives
University of California, San Francisco (UCSF)

First trimester abortions are just as safe when performed by trained nurse practitioners, physician assistants and certified nurse midwives as when conducted by physicians, according to a new six-year study led by UCSF.

Released: 17-Jan-2013 1:45 PM EST
Irregular Heart Beat Elevates Risk of Kidney Failure
University of California, San Francisco (UCSF)

Many people who suffer from chronic kidney disease progressively lose their kidney function over time and eventually develop a condition called end-stage renal disease – the complete failure of the kidneys – placing them in need of lifelong dialysis or a kidney transplant.

Released: 10-Jan-2013 12:10 PM EST
UCSF Teams Tackle Childhood Mortality and River Blindness
University of California, San Francisco (UCSF)

Two UCSF teams have received a total of $16 million from the Bill & Melinda Gates Foundation to study new ways to significantly reduce childhood mortality and disease in developing nations.

7-Jan-2013 3:00 PM EST
Drug-Resistant Melanoma Tumors Shrink When Therapy Is Interrupted
University of California, San Francisco (UCSF)

Researchers in California and Switzerland have discovered that melanomas that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf), also develop addiction to the drug, an observation that may have important implications for the lives of patients with late-stage disease.

Released: 9-Jan-2013 12:00 PM EST
UCSF Helen Diller Cancer Center Awarded $36 Million Grant
University of California, San Francisco (UCSF)

The National Cancer Institute has awarded the UCSF Helen Diller Family Comprehensive Cancer Center a $36 million grant to fund cutting edge research programs and clinical trials over five years.



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