Credit: Dr. Dana Graves Lab
In skin from mice with normal glucose levels (top row), more skin cells (red) migrate into damaged tissue in control mice (left) than in mice lacking FOXO1 (right). But in diabetic mice (bottom row), more skin cells migrate into the wound in animals lacking FOXO1 (right) than in controls (left). Blue marks cell nuclei, and the dotted line delineates the boundary between the epidermis and the dermis.